Plasma urate and risk of Parkinson's disease.

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Published in Am J Epidemiol on June 20, 2007

Authors

M G Weisskopf1, E O'Reilly, H Chen, M A Schwarzschild, A Ascherio

Author Affiliations

1: Department of Environmental Health, Harvard School of Public Health, Boston, MA 02215, USA. mweissko@hsph.harvard.edu

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Hemiballismus. AJNR Am J Neuroradiol (1994) 2.16

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