PubRank

K O'Rourke

Author PubWeight™ 186.96‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex. Cell 1996 12.07
2 Conflict of interest in the debate over calcium-channel antagonists. N Engl J Med 1998 11.14
3 FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 1995 9.81
4 Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 1995 9.22
5 The receptor for the cytotoxic ligand TRAIL. Science 1997 6.39
6 Meta-analysis in clinical research. Ann Intern Med 1987 5.16
7 Incorporating variations in the quality of individual randomized trials into meta-analysis. J Clin Epidemiol 1992 4.86
8 Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma. Mol Cell 2000 4.19
9 Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases. J Biol Chem 1996 3.97
10 On the bias produced by quality scores in meta-analysis, and a hierarchical view of proposed solutions. Biostatistics 2001 3.83
11 FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis. J Biol Chem 1996 3.72
12 Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis. Ann Intern Med 1993 3.53
13 Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death. Science 1997 3.51
14 A novel RING finger protein interacts with the cytoplasmic domain of CD40. J Biol Chem 1994 3.13
15 Parenteral nutrition with branched-chain amino acids in hepatic encephalopathy. A meta-analysis. Gastroenterology 1989 2.88
16 Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 1996 2.87
17 Role of CED-4 in the activation of CED-3. Nature 1997 2.76
18 Intravenous immunoglobulin therapy for streptococcal toxic shock syndrome--a comparative observational study. The Canadian Streptococcal Study Group. Clin Infect Dis 1999 2.69
19 Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin. J Biol Chem 1990 2.37
20 Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex. J Biol Chem 1998 2.25
21 Randomized, controlled trial of an interactive videodisc decision aid for patients with ischemic heart disease. J Gen Intern Med 2000 2.21
22 Asymptomatic primary biliary cirrhosis: a study of its natural history and prognosis. Am J Gastroenterol 1999 2.19
23 A randomized crossover trial of Quick Medical Reference (QMR) as a teaching tool for medical interns. J Gen Intern Med 1994 2.10
24 A role for FADD in T cell activation and development. Immunity 1998 2.09
25 Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B. Proc Natl Acad Sci U S A 1996 1.90
26 Prophylactic mesalamine treatment decreases postoperative recurrence of Crohn's disease. Gastroenterology 1995 1.90
27 Age distribution of Helicobacter pylori seroprevalence among young children in a United States/Mexico border community: evidence for transitory infection. Am J Epidemiol 1999 1.68
28 Perioperative parenteral nutrition: a meta-analysis. Ann Intern Med 1987 1.62
29 Direct costs of coronary artery bypass grafting in patients aged 65 years or more and those under age 65. CMAJ 1999 1.61
30 Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases. J Biol Chem 1996 1.57
31 Cost induced by hip fractures. Ir Med J 2008 1.46
32 Preoperative fasting for preventing perioperative complications in children. Cochrane Database Syst Rev 2005 1.45
33 Autoimmune encephalopathy presenting as a 'posterior circulation stroke'. J Neurol 2010 1.45
34 OAS1: a multiple sclerosis susceptibility gene that influences disease severity. Neurology 2010 1.45
35 Identification of an epitope in the C terminus of normal prion protein whose expression is modulated by binding events in the N terminus. J Mol Biol 2000 1.44
36 Improving prevention in primary care: evaluating the effectiveness of outreach facilitation. Fam Pract 2008 1.40
37 Thrombospondin-induced adhesion of human keratinocytes. J Clin Invest 1988 1.33
38 Predicting nutrition-associated complications for patients undergoing gastrointestinal surgery. JPEN J Parenter Enteral Nutr 1987 1.32
39 Residential mobility and risk of childhood acute lymphoblastic leukaemia: an ecological study. Br J Cancer 2007 1.30
40 Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development. J Biol Chem 1992 1.27
41 Cost-effectiveness analysis of potential improvements to emergency medical services for victims of out-of-hospital cardiac arrest. Ann Emerg Med 1996 1.21
42 A second, expressed thrombospondin gene (Thbs2) exists in the mouse genome. J Biol Chem 1991 1.15
43 Effectiveness of emergency medical services for victims of out-of-hospital cardiac arrest: a metaanalysis. Ann Emerg Med 1996 1.15
44 Synthesis of wild type and mutant human hemoglobins in Saccharomyces cerevisiae. Biotechnology (N Y) 1991 1.14
45 High level thrombospondin 1 expression in two NIH 3T3 cloned lines confers serum- and anchorage-independent growth. J Biol Chem 1993 1.09
46 Lymphocyte function-associated antigen 1 overexpression and T cell autoreactivity. Arthritis Rheum 1994 1.09
47 Stability of treatment preferences: although most preferences do not change, most people change some of their preferences. J Clin Ethics 1997 1.07
48 "Sixteen and a half": a novel pontine neuro-ophthalmological syndrome. J Neurol 2011 1.07
49 Inhibition of platelet aggregation by a monoclonal antibody against human fibronectin. Proc Natl Acad Sci U S A 1985 1.06
50 The anterolateral approach leads to less disruption of the femoral head-neck blood supply than the posterior approach during hip resurfacing. J Bone Joint Surg Br 2007 1.03
51 A randomized trial of a decisional aid for mental capacity assessments. J Clin Epidemiol 1993 1.02
52 Anti-NMDA receptor encephalitis with associated catatonia during pregnancy. J Neurol 2012 1.02
53 Is the Mayo model for predicting survival useful after the introduction of ursodeoxycholic acid treatment for primary biliary cirrhosis? Hepatology 1996 0.98
54 A prospective study of peri-diagnostic and surgical wait times for patients with presumptive colorectal, lung, or prostate cancer. Br J Cancer 2008 0.93
55 Elevated levels of syndecan-1 expression confer potent serum-dependent growth in human 293T cells. Cancer Res 1995 0.93
56 Hepatitis A among schoolchildren in a US-Mexico border community. Am J Public Health 1997 0.92
57 APC I1307K increases risk of transition from polyp to colorectal carcinoma in Ashkenazi Jews. Gastroenterology 2001 0.92
58 Parenteral nutrition in cancer patients undergoing chemotherapy: a meta-analysis. Nutrition 1992 0.92
59 A comparison of three rapid D-dimer methods for the diagnosis of venous thromboembolism. Br J Haematol 2001 0.92
60 Thrombospondin binding by human squamous carcinoma and melanoma cells: relationship to biological activity. Exp Cell Res 1988 0.91
61 Elevated hepatitis A and E seroprevalence rates in a Texas/Mexico border community. Tex Med 1998 0.91
62 Anti-glycolipid GM2-positive Guillain-Barre syndrome due to hepatitis E infection. Ir J Med Sci 2010 0.91
63 Postoperative analgesia after lumbar laminectomy: epidural fentanyl infusion versus patient-controlled intravenous morphine. Anesth Analg 1995 0.89
64 Age-specific incidence of hip fracture in the elderly: a healthy decline. Surgeon 2010 0.89
65 A review of antigenic variation by the equine infectious anemia virus. Contrib Microbiol Immunol 1987 0.89
66 Expression and analysis of COOH-terminal deletions of the human thrombospondin molecule. J Cell Biol 1989 0.88
67 An analysis of skin perfusion over the achilles tendon in varying degrees of plantarflexion. Foot Ankle Int 2001 0.88
68 The Brophy case: the use of artificial hydration and nutrition. Linacre Q 1987 0.87
69 The longitudinal relationship between the patient-reported Multiple Sclerosis Impact Scale and the clinician-assessed Multiple Sclerosis Functional Composite. Mult Scler 2007 0.86
70 Risk factor analysis of peri-neonatal mortality in rural Guatemala. Bull Pan Am Health Organ 1994 0.86
71 Evaluation of short-course therapy with cefixime or rifampin for eradication of pharyngeally carried group A streptococci. The Ontario GAS Study Group. Clin Infect Dis 1995 0.86
72 Containing Ontario's hospital costs under universal insurance in the 1980s: what was the record? CMAJ 1990 0.85
73 Primary biliary cirrhosis, sicca complex, and dysphagia. Dysphagia 1997 0.85
74 The association of hepatitis C viral infection with porphyria cutanea tarda in the Lothian region of Scotland. Clin Exp Dermatol 1996 0.84
75 Risk and significance of endoscopic/radiological evidence of recurrent Crohn's disease. Gastroenterology 1997 0.84
76 Increased prevalence and analysis of risk factors for indinavir nephrolithiasis. J Urol 2000 0.84
77 Age as a determinant of cardiopulmonary resuscitation outcome in the coronary care unit. J Am Geriatr Soc 1995 0.84
78 The death inhibitory molecules CED-9 and CED-4L use a common mechanism to inhibit the CED-3 death protease. J Biol Chem 1998 0.84
79 Functional status is well maintained in older women during adjuvant chemotherapy for breast cancer. Ann Oncol 2003 0.83
80 The interaction of human immunodeficiency virus infection and hepatitis B virus infection in infected homosexual men. J Clin Gastroenterol 1996 0.83
81 Does treatment with essential amino acids and hypertonic glucose improve survival in acute renal failure?: A meta-analysis. Ren Fail 1988 0.82
82 First identified case of VIM-producing carbapenem-resistant Klebsiella pneumoniae in the Republic of Ireland associated with fatal outcome. Euro Surveill 2010 0.81
83 Assisted suicide: an evaluation. J Pain Symptom Manage 1991 0.80
84 The Face-Symbol Test and the Symbol-Digit Test are not reliable surrogates for the Paced Auditory Serial Addition Test in multiple sclerosis. Mult Scler 2006 0.80
85 Purpura fulminans in a patient with paroxysmal nocturnal haemoglobinuria. Intern Med J 2013 0.80
86 Predictive value of cytomegalovirus (CMV) antigenemia and digene hybrid capture DNA assays for CMV disease in human immunodeficiency virus-infected patients. Clin Infect Dis 1998 0.79
87 Mechanisms of changes in renal handling of sodium following transjugular intrahepatic portal systemic stent-shunt (TIPSS). Eur J Gastroenterol Hepatol 1996 0.79
88 The histologic estimation of coronary artery stenoses: accuracy and the effect of lumen shape. Cardiovasc Pathol 2001 0.79
89 Regulatory intensity, hospital size and the formalization of medical staff organization in hospitals. Health Serv Manage Res 1992 0.79
90 Pain relief: the perspective of Catholic tradition. J Pain Symptom Manage 1992 0.79
91 Expression and chromosomal localization of cDNA clones from an enriched human retinal pigment epithelial (RPE) cell line library: identification of two RPE-specific genes. Cytogenet Cell Genet 1995 0.79
92 Participation rates of Ashkenazi Jews in a colon cancer community-based screening/prevention study. Clin Genet 2002 0.78
93 Job satisfaction among nursing staff in a military health care facility. Mil Med 2000 0.78
94 Reflex sympathetic dystrophy associated with extraforaminal disc herniation at the L5-S1 level. J Spinal Disord 1998 0.77
95 Development of a model for occipital fixation--validation of an analogue bone material. Proc Inst Mech Eng H 2002 0.77
96 Evidence for redundancy in cysteine biosynthesis in Rhizobium leguminosarum RL3841: analysis of a cysE gene encoding serine acetyltransferase. Microbiology 2001 0.76
97 The hazards of using active clinic patients as a source of subjects for clinical studies. J Gen Intern Med 1988 0.76
98 Meta-analysis of highly selective vagotomy versus truncal vagotomy and pyloroplasty in the surgical treatment of uncomplicated duodenal ulcer. Can J Surg 1994 0.76
99 Accuracy of substituted judgments in patients with terminal diagnoses. Ann Intern Med 1998 0.75
100 Two cheers for Bayes. Control Clin Trials 1996 0.75
101 Deciding life and death in the courtroom: debate and clarification. JAMA 1998 0.75
102 Trust and the patient-physician relationship. Am J Kidney Dis 1993 0.75
103 Immunocytochemical colocalization of clusterin in apoptotic photoreceptor cells in retinal degeneration slow rds mutant mouse retinas. Biochem Biophys Res Commun 1996 0.75
104 An exchange on Directive 58. Health Prog 2000 0.75
105 On the alleged protective effect of stratification against "type I" error. J Clin Epidemiol 1999 0.75
106 Laparoscopic diagnosis and resection of a bleeding Meckel's diverticulum in a thirteen year old female. Ir J Med Sci 1996 0.75
107 An ethical perspective on investor-owned medical care corporations. Front Health Serv Manage 1984 0.75
108 Application of a stopping rule based on total treatment failures: the postoperative Crohn's disease trial. J Clin Epidemiol 1992 0.75
109 Should nutrition and hydration be provided to permanently unconscious and other mentally disabled persons? Issues Law Med 1989 0.75
110 Amnestic syndrome due to meningovascular neurosyphilis. J Neurol 2009 0.75
111 The anthrax detectives. J Am Vet Med Assoc 2001 0.75
112 Ethical, legal, and psychodynamic considerations in intervention of a possible cult member. J Am Acad Child Adolesc Psychiatry 1990 0.75
113 Long-term follow-up of a randomized trial of interferon therapy for chronic hepatitis B in a predominantly homosexual male population. J Hepatol 1999 0.75
114 Do geriatric programs decrease long-term use of acute care beds? J Am Geriatr Soc 1995 0.75
115 Müller and retinal pigment epithelial (RPE) cell expression of NGFI-A and c-fos mRNA in response to medium conditioned by the RPE. Brain Res Mol Brain Res 1995 0.75
116 Hemispheric stroke following cardiac surgery: a case-control estimate of the risk resulting from ipsilateral asymptomatic carotid artery stenosis. Ann Vasc Surg 2000 0.75
117 Hepatitis B and C among adolescents at an STD clinic on the US-Mexico border. Tex Med 2001 0.75
118 Evolution of Church teaching on prolonging life. Health Prog 1988 0.75
119 Fight unions, not unity. Favor unions and unity. Nursing 1985 0.75
120 Do low observed error rates lessen the need for study-specific data quality audits? Control Clin Trials 1996 0.75
121 Case of the month: atlanto-axial rotatory fixation. Br J Radiol 1995 0.75
122 Granulomatosis with polyangiitis masquerading as giant cell arteritis. J Neurol 2013 0.75
123 Kidney transplantation from anencephalic donors. N Engl J Med 1987 0.75
124 The clinical utility of CMV surveillance cultures and antigenemia following bone marrow transplantation. Bone Marrow Transplant 1999 0.75
125 The role of a movement disorders clinic. Ir Med J 2012 0.75
126 Catholic hospitals and unions. Health Care Ethics USA 2000 0.75
127 Histologic estimation of coronary artery stenoses: reproducibility and the effect of training. Cardiovasc Pathol 2000 0.75
128 Drug rehabilitation in the combat zone. Mil Med 1974 0.75