Published in J Biol Chem on February 15, 1990
Frequent inactivation of A20 in B-cell lymphomas. Nature (2009) 4.22
A20: central gatekeeper in inflammation and immunity. J Biol Chem (2008) 2.83
Encoding NF-kappaB temporal control in response to TNF: distinct roles for the negative regulators IkappaBalpha and A20. Genes Dev (2008) 2.29
Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis. Am J Pathol (1991) 2.24
Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells. J Exp Med (1992) 2.15
A20: from ubiquitin editing to tumour suppression. Nat Rev Cancer (2010) 2.08
Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene. J Virol (1996) 2.03
An NF kappa B-like factor is essential but not sufficient for cytokine induction of endothelial leukocyte adhesion molecule 1 (ELAM-1) gene transcription. Nucleic Acids Res (1991) 1.94
Molecular basis for the unique deubiquitinating activity of the NF-kappaB inhibitor A20. J Mol Biol (2007) 1.82
Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors. J Biol Chem (2008) 1.80
Expression of monocyte chemoattractant protein 1 mRNA in human idiopathic pulmonary fibrosis. Proc Natl Acad Sci U S A (1992) 1.78
Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2. Cancer Res (2009) 1.61
Elevated expression of monocyte chemoattractant protein 1 by vascular smooth muscle cells in hypercholesterolemic primates. Proc Natl Acad Sci U S A (1992) 1.42
The cysteine-cysteine family of chemokines RANTES, MIP-1alpha, and MIP-1beta induce trypanocidal activity in human macrophages via nitric oxide. Infect Immun (1998) 1.39
Shiga toxin-associated hemolytic uremic syndrome: interleukin-1 beta enhancement of Shiga toxin cytotoxicity toward human vascular endothelial cells in vitro. Infect Immun (1993) 1.31
A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein. Mol Cell Biol (1990) 1.25
Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases. Genes Immun (2011) 1.24
Modulation of keratinocyte-derived interleukin-8 which is chemotactic for neutrophils and T lymphocytes. Am J Pathol (1991) 1.24
Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors. EMBO J (1994) 1.24
Genome-wide transcriptional response of primary alveolar macrophages following infection with porcine reproductive and respiratory syndrome virus. J Gen Virol (2008) 1.17
Expression of monocyte chemotactic protein-1 in human melanoma in vivo. Am J Pathol (1992) 1.17
Rous-Whipple Award Lecture. Atherosclerosis: a defense mechanism gone awry. Am J Pathol (1993) 1.15
Interleukin 8 secretion by colonic crypt cells in vitro: response to injury suppressed by butyrate and enhanced in inflammatory bowel disease. Gut (1995) 1.15
Hydrogen peroxide-mediated toxicity for Leishmania donovani chagasi promastigotes. Role of hydroxyl radical and protection by heat shock. J Clin Invest (1991) 1.13
Dendritic cells for active anti-cancer immunotherapy: targeting activation pathways through genetic modification. Endocr Metab Immune Disord Drug Targets (2009) 1.01
Lipopolysaccharide-inducible and salicylate-sensitive nuclear factor(s) on human tumor necrosis factor alpha promoter. Infect Immun (1995) 1.00
TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions. PLoS One (2011) 0.98
Expression of tumor necrosis factor by different tumor cell lines results either in tumor suppression or augmented metastasis. J Exp Med (1993) 0.96
Genome-wide analysis of the stress associated protein (SAP) gene family containing A20/AN1 zinc-finger(s) in rice and their phylogenetic relationship with Arabidopsis. Mol Genet Genomics (2006) 0.90
Receptor tyrosine kinase EphA2 mediates thrombin-induced upregulation of ICAM-1 in endothelial cells in vitro. Thromb Res (2008) 0.90
A novel stress-associated protein 'AtSAP10' from Arabidopsis thaliana confers tolerance to nickel, manganese, zinc, and high temperature stress. PLoS One (2011) 0.88
The role of A20 in the pathogenesis of lymphocytic malignancy. Cancer Cell Int (2012) 0.87
Characterization of the molecular interplay between Moraxella catarrhalis and human respiratory tract epithelial cells. PLoS One (2013) 0.87
The zinc finger transcription factor EGR-1 impedes interleukin-1-inducible tumor growth arrest. Mol Cell Biol (1995) 0.86
Regulatory roles of tumor necrosis factor-alpha and interleukin-1 beta in monocyte chemoattractant protein-1-mediated pulmonary granuloma formation in the rat. Am J Pathol (1995) 0.85
Induction of protective genes leads to islet survival and function. J Transplant (2011) 0.85
Involvement of A20 in the molecular switch that activates the non-canonical NF-кB pathway. Sci Rep (2013) 0.85
A20 is induced by Kaposi sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 and blocks K13-induced nuclear factor-kappaB in a negative feedback manner. J Biol Chem (2011) 0.84
A20 suppresses hepatocellular carcinoma proliferation and metastasis through inhibition of Twist1 expression. Mol Cancer (2015) 0.84
Role of A20 in interferon-α-mediated functional restoration of myeloid dendritic cells in patients with chronic hepatitis C. Immunology (2014) 0.83
Human growth factor (huGRO), interleukin-8 (IL-8) and interferon-gamma-inducible protein (gamma-IP-10) gene expression in cultured normal human keratinocytes. Arch Dermatol Res (1994) 0.83
Escape from transcriptional shutoff during poliovirus infection: NF-κB-responsive genes IκBa and A20. J Virol (2011) 0.82
Immunoregulatory Effects Triggered by Lactic Acid Bacteria Exopolysaccharides: New Insights into Molecular Interactions with Host Cells. Microorganisms (2016) 0.81
Upregulated Expression of A20 on Monocytes is Associated With Increased Severity of Acute-on-Chronic Hepatitis B Liver Failure: A Case-Control Study. Medicine (Baltimore) (2015) 0.81
Genetics of SLE: functional relevance for monocytes/macrophages in disease. Clin Dev Immunol (2012) 0.81
Characterization and phylogenetic analysis of environmental stress-responsive SAP gene family encoding A20/AN1 zinc finger proteins in tomato. Mol Genet Genomics (2009) 0.81
Alternative expression pattern of MALT1-A20-NF-κB in patients with rheumatoid arthritis. J Immunol Res (2014) 0.80
Targeting lentiviral vectors for cancer immunotherapy. Curr Cancer Ther Rev (2011) 0.80
Aberrant expression of the dendritic cell marker TNFAIP2 by the malignant cells of Hodgkin lymphoma and primary mediastinal large B-cell lymphoma distinguishes these tumor types from morphologically and phenotypically similar lymphomas. Am J Surg Pathol (2011) 0.79
Endothelial cell regulation of leukocyte infiltration in inflammatory tissues. Mediators Inflamm (1995) 0.79
A20 is critical for the induction of Pam3CSK4-tolerance in monocytic THP-1 cells. PLoS One (2014) 0.79
Identification of the NF-κB inhibitor A20 as a key regulator for human adipogenesis. Cell Death Dis (2013) 0.79
Effect of pulsed electromagnetic field on inflammatory pathway markers in RAW 264.7 murine macrophages. J Inflamm Res (2013) 0.78
Epigenetics in myeloid derived suppressor cells: a sheathed sword towards cancer. Oncotarget (2016) 0.78
Role of A20 in cIAP-2 protection against tumor necrosis factor α (TNF-α)-mediated apoptosis in endothelial cells. Int J Mol Sci (2014) 0.78
Altered expression of A20 gene in peripheral blood mononuclear cells is associated with the progression of chronic hepatitis B virus infection. Oncotarget (2016) 0.78
Novel heterozygous C243Y A20/TNFAIP3 gene mutation is responsible for chronic inflammation in autosomal-dominant Behçet's disease. RMD Open (2016) 0.77
Gene expression profiling of porcine mammary epithelial cells after challenge with Escherichia coli and Staphylococcus aureus in vitro. Vet Res (2015) 0.77
Design of a zinc finger protein binding a sequence upstream of the A20 gene. BMC Biotechnol (2008) 0.77
EphA2-receptor deficiency exacerbates myocardial infarction and reduces survival in hyperglycemic mice. Cardiovasc Diabetol (2014) 0.77
Limiting inflammation-the negative regulation of NF-κB and the NLRP3 inflammasome. Nat Immunol (2017) 0.76
Inhibition of A20 expression in tumor microenvironment exerts anti-tumor effect through inducing myeloid-derived suppressor cells apoptosis. Sci Rep (2015) 0.76
Upregulation of neuronal zinc finger protein A20 expression is required for electroacupuncture to attenuate the cerebral inflammatory injury mediated by the nuclear factor-kB signaling pathway in cerebral ischemia/reperfusion rats. J Neuroinflammation (2016) 0.75
The nuclear factor-κB pathway down-regulates expression of the NKG2D ligand H60a in vitro: implications for use of nuclear factor-κB inhibitors in cancer therapy. Immunology (2013) 0.75
Does antigen masking by ubiquitin chains protect from the development of autoimmune diseases? Front Immunol (2014) 0.75
A20 deficiency leads to angiogenesis of pulmonary artery endothelial cells through stronger NF-κB activation under hypoxia. J Cell Mol Med (2016) 0.75
A20 targets caspase-8 and FADD to protect HTLV-I-infected cells. Leukemia (2015) 0.75
Charactering the ZFAND3 gene mapped in the sex-determining locus in hybrid tilapia (Oreochromis spp.). Sci Rep (2016) 0.75
Stimulus-Dependent Inhibitor of Apoptosis Protein Expression Prolongs the Duration of B Cell Signalling. Sci Rep (2016) 0.75
Functional effect of polymorphisms in the promoter of TNFAIP3 (A20) in acute pancreatitis in the Han Chinese population. PLoS One (2014) 0.75
Novel A20-gene-eluting stent inhibits carotid artery restenosis in a porcine model. Drug Des Devel Ther (2016) 0.75
Transcriptomics and methylomics of CD4-positive T cells in arsenic-exposed women. Arch Toxicol (2016) 0.75
Downregulation of A20 increases the cytotoxicity of IFN-γ in hepatocellular carcinoma cells. Drug Des Devel Ther (2017) 0.75
Transcriptome wide identification, phylogenetic analysis, and expression profiling of zinc-finger transcription factors from Crocus sativus L. Mol Genet Genomics (2017) 0.75
Genome-wide identification and expression analysis of stress-associated proteins (SAPs) containing A20/AN1 zinc finger in cotton. Mol Genet Genomics (2016) 0.75
An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci U S A (1975) 23.42
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex. Cell (1996) 12.07
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature (1990) 11.92
Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity. J Infect Dis (2000) 11.44
Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature (1986) 11.35
Conflict of interest in the debate over calcium-channel antagonists. N Engl J Med (1998) 11.14
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell (1995) 9.81
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell (1995) 9.22
Further studies on the chemotactic factor of complement and its formation in vivo. Immunology (1966) 7.59
MYC oncogenes and human neoplastic disease. Oncogene (1999) 7.28
Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate. Nat Med (1997) 6.57
Functional domains of the human estrogen receptor. Cell (1987) 6.52
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40. Science (1995) 6.41
The receptor for the cytotoxic ligand TRAIL. Science (1997) 6.39
Undertreatment of medical inpatients with narcotic analgesics. Ann Intern Med (1973) 6.24
Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor. EMBO J (1986) 6.08
Nuclear receptors enhance our understanding of transcription regulation. Trends Genet (1988) 5.95
Bacterial factors chemotactic for polymorphonuclear leukocytes. Am J Pathol (1968) 5.77
Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor. Nature (1987) 5.47
Meta-analysis in clinical research. Ann Intern Med (1987) 5.16
Dengue in the early febrile phase: viremia and antibody responses. J Infect Dis (1997) 5.13
Early clinical and laboratory indicators of acute dengue illness. J Infect Dis (1997) 5.00
Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-alpha, LPS, and IL-1 beta. Science (1989) 4.99
A plasmin-split fragment of C'3 as a new chemotactic factor. J Exp Med (1967) 4.94
Maintaining low HIV seroprevalence in populations of injecting drug users. JAMA (1995) 4.88
Incorporating variations in the quality of individual randomized trials into meta-analysis. J Clin Epidemiol (1992) 4.86
The deactivation of rabbit neutrophils by chemotactic factor and the nature of the activatable esterase. J Exp Med (1968) 4.79
Cloning of the human estrogen receptor cDNA. Proc Natl Acad Sci U S A (1985) 4.58
The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors. EMBO J (1986) 4.47
A neutrophil chemotactic factor from human C'5. J Immunol (1969) 4.46
Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions. Am J Pathol (1982) 4.38
The yeast UASG is a transcriptional enhancer in human HeLa cells in the presence of the GAL4 trans-activator. Cell (1988) 4.22
Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma. Mol Cell (2000) 4.19
The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function. Cell (1988) 4.17
Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases. J Biol Chem (1996) 3.97
Leukotactic factor produced by sensitized lymphocytes. Science (1969) 3.95
The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking sequence of the rat acyl CoA oxidase gene. EMBO J (1992) 3.92
Mechanisms of the inhibition of chemotaxis by phosphonate esters. J Exp Med (1967) 3.87
On the bias produced by quality scores in meta-analysis, and a hierarchical view of proposed solutions. Biostatistics (2001) 3.83
The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell (1996) 3.82
C5 chemotactic fragments produced by an enzyme in lysosomal granules of neutrophils. J Immunol (1970) 3.75
FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis. J Biol Chem (1996) 3.72
Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxifylline. Biochem Biophys Res Commun (1988) 3.63
Adhesion molecules and inflammatory injury. FASEB J (1994) 3.53
Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis. Ann Intern Med (1993) 3.53
Acute immunologic pulmonary alveolitis. J Clin Invest (1974) 3.53
Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death. Science (1997) 3.51
The isolation and partial characterization of neutrophil chemotactic factors from Escherichia coli. J Immunol (1975) 3.50
Intravascular activation of complement and acute lung injury. Dependency on neutrophils and toxic oxygen metabolites. J Clin Invest (1982) 3.49
Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo. Proc Natl Acad Sci U S A (1999) 3.49
Screening for prostate cancer. Cochrane Database Syst Rev (2006) 3.46
Purification and identification of formyl-methionyl-leucyl-phenylalanine as the major peptide neutrophil chemotactic factor produced by Escherichia coli. J Biol Chem (1984) 3.32
Length of uninterrupted CGG repeats determines instability in the FMR1 gene. Nat Genet (1994) 3.22
Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin. J Clin Invest (2001) 3.22
The production by antigen-stimulated lymphocytes of a leukotactic factor distinct from migration inhibitory factor. Cell Immunol (1970) 3.17
Partial biochemical characterization of the activated esterase required in the complement-dependent chemotaxis of rabbit polymorphonuclear leukocytes. J Exp Med (1967) 3.15
A novel RING finger protein interacts with the cytoplasmic domain of CD40. J Biol Chem (1994) 3.13
Genetic locus (ompB) affecting a major outer-membrane protein in Escherichia coli K-12. J Bacteriol (1977) 3.10
ELAM-1--dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA. Cell (1990) 2.97
The phlogistic role of C3 leukotactic fragments in myocardial infarcts of rats. J Exp Med (1971) 2.95
Chemotoxis of mononuclear cells. J Exp Med (1968) 2.95
Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis. Science (1995) 2.88
Parenteral nutrition with branched-chain amino acids in hepatic encephalopathy. A meta-analysis. Gastroenterology (1989) 2.88
Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science (1996) 2.87
Role of CED-4 in the activation of CED-3. Nature (1997) 2.76
Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. Science (1993) 2.71
Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation. Mol Cell Biol (1988) 2.70
Intravenous immunoglobulin therapy for streptococcal toxic shock syndrome--a comparative observational study. The Canadian Streptococcal Study Group. Clin Infect Dis (1999) 2.69
Genomic organization of the human oestrogen receptor gene. EMBO J (1988) 2.65
The chemosuppression of chemotaxis. J Exp Med (1966) 2.62
Deregulated expression of c-myc by murine erythroleukaemia cells prevents differentiation. Nature (1986) 2.54
Short course prednisolone for adhesive capsulitis (frozen shoulder or stiff painful shoulder): a randomised, double blind, placebo controlled trial. Ann Rheum Dis (2004) 2.54
Evidence for role of hydroxyl radical in complement and neutrophil-dependent tissue injury. J Clin Invest (1983) 2.52
Isolation of type C virions from a normal human fibroblast strain. Science (1975) 2.52
Protective effects of C5a blockade in sepsis. Nat Med (1999) 2.50
Chemical generation of nitric oxide in the mouth from the enterosalivary circulation of dietary nitrate. Nat Med (1995) 2.50
Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats. J Clin Invest (1991) 2.50
A new method of estimating prevalence of injecting drug use in an urban population: results from a Scottish city. Int J Epidemiol (1991) 2.49
Tissue injury caused by deposition of immune complexes is L-arginine dependent. Proc Natl Acad Sci U S A (1991) 2.49
The 40K activity of one gram of potassium. Phys Med Biol (1997) 2.48
Neutrophil-dependent acute lung injury. Requirement for P-selectin (GMP-140). J Clin Invest (1992) 2.47
Effect of tumour necrosis factor on cultured human melanoma cells. Nature (1975) 2.46
Monokine-induced neutrophil chemotactic factor gene expression in human fibroblasts. J Biol Chem (1989) 2.43
Partial purification of a serum factor that causes necrosis of tumors. Proc Natl Acad Sci U S A (1976) 2.42
A superfamily of potentially oncogenic hormone receptors. Nature (1987) 2.40
Role of oxygen metabolites in immune complex injury of lung. J Immunol (1981) 2.39
In vitro and in vivo activity of a lymphocyte and immune complex-dependent chemotactic factor for eosinophils. J Exp Med (1971) 2.36
Complement-derived leukotactic factors in inflammatory synovial fluids of humans. J Clin Invest (1971) 2.35
Neutrophil aggregation and swelling induced by chemotactic agents. J Immunol (1977) 2.26
Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex. J Biol Chem (1998) 2.25
Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis. Am J Pathol (1991) 2.24
Corticosteroid injections for shoulder pain. Cochrane Database Syst Rev (2003) 2.23
Evidence for soluble immune complexes in the pathogenesis of the glomerulonephritis of quartan malaria. Lancet (1969) 2.22
Randomized, controlled trial of an interactive videodisc decision aid for patients with ischemic heart disease. J Gen Intern Med (2000) 2.21
Asymptomatic primary biliary cirrhosis: a study of its natural history and prognosis. Am J Gastroenterol (1999) 2.19
C3 leukotactic factors produced by a tissue protease. J Exp Med (1969) 2.19
HLA-A and -B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais. Tissue Antigens (2002) 2.18
Mortality among injecting drug users: a critical reappraisal. J Epidemiol Community Health (1993) 2.17