Published in Gastroenterology on August 01, 1995
Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo. Am J Pathol (2005) 3.88
KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors. Am J Pathol (2000) 2.99
Gastrointestinal stromal tumors. Virchows Arch (2010) 2.28
Gastrointestinal stromal tumor. J Gastrointest Oncol (2012) 1.57
The T3R alpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production. EMBO J (1997) 1.54
Pathophysiology, diagnosis, and treatment of gastrointestinal stromal tumors. J Gastroenterol (2005) 1.44
Interstitial Cajal-like cells in human gallbladder. J Mol Histol (2007) 1.38
Mounting evidence against the role of ICC in neurotransmission to smooth muscle in the gut. Am J Physiol Gastrointest Liver Physiol (2009) 1.26
Embryonic form of smooth muscle myosin heavy chain (SMemb/MHC-B) in gastrointestinal stromal tumor and interstitial cells of Cajal. Am J Pathol (1999) 1.23
Pyloric sphincter dysfunction in nNOS-/- and W/Wv mutant mice: animal models of gastroparesis and duodenogastric reflux. Gastroenterology (2008) 1.10
Gastrointestinal stromal tumors: past, present, and future. J Gastroenterol (2008) 1.09
Molecular basis for primary and secondary tyrosine kinase inhibitor resistance in gastrointestinal stromal tumor. Cancer Chemother Pharmacol (2010) 1.08
Expression of protooncogene c-kit and its ligand stem cell factor (SCF) in gastric carcinoma cell lines. Dig Dis Sci (1998) 1.02
The significance of interstitial cells in neurogastroenterology. J Neurogastroenterol Motil (2014) 1.01
C-Kit receptor (CD117) in the porcine urinary tract. Pediatr Surg Int (2008) 1.00
The reappraisal of gastrointestinal stromal tumors: from Stout to the KIT revolution. Virchows Arch (2003) 0.99
Interstitial cells of Cajal in the normal human gut and in Hirschsprung disease. Pediatr Surg Int (2013) 0.96
Cajal-like cells in the upper urinary tract: comparative study in various species. Pediatr Surg Int (2005) 0.96
Interstitial cells of Cajal in the normal gut and in intestinal motility disorders of childhood. Pediatr Surg Int (2007) 0.94
Gain-of-Function Mutations of Receptor Tyrosine Kinases in Gastrointestinal Stromal Tumors. Curr Genomics (2006) 0.93
Multiple solid pancreatic hamartomas: A case report and review of the literature. World J Gastrointest Oncol (2012) 0.91
Mutation assay of the novel gene DOG1 in gastrointestinal stromal tumors (GISTs). J Gastroenterol (2008) 0.87
Role of KIT-Positive Interstitial Cells of Cajal in the Urinary Bladder and Possible Therapeutic Target for Overactive Bladder. Adv Urol (2011) 0.86
Restoration of gut motility in Kit-deficient mice by bone marrow transplantation. J Gastroenterol (2009) 0.83
Expression of c-kit receptor in human cholangiocarcinoma and in vivo treatment with imatinib mesilate in chimeric mice. World J Gastroenterol (2006) 0.83
In vivo recording of colonic motility in conscious rats with deficiency of interstitial cells of Cajal, with special reference to the effects of nitric oxide on colonic motility. J Gastroenterol (2005) 0.79
Therapy-refractory gastrointestinal motility disorder in a child with c-kit mutations. World J Gastroenterol (2010) 0.79
Constipation and lack of colonic interstitial cells of Cajal. Dig Dis Sci (2003) 0.78
The identification of specialized pacemaking cells in the anal sphincters. Int J Colorectal Dis (2005) 0.77
Is Interstitial Cells of Cajal‒opathy Present in Gastroparesis? J Neurogastroenterol Motil (2015) 0.75
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science (1998) 21.13
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell (1997) 18.91
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun (1999) 14.25
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature (1995) 11.06
Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature (1996) 10.67
Lethal effect of the anti-Fas antibody in mice. Nature (1993) 9.20
The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature (1998) 7.38
A novel murine oncornavirus with dual eco- and xenotropic properties. Proc Natl Acad Sci U S A (1975) 5.91
Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation. Blood (1978) 5.18
A novel subtype of type 1 diabetes mellitus characterized by a rapid onset and an absence of diabetes-related antibodies. Osaka IDDM Study Group. N Engl J Med (2000) 4.73
Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease. Science (2000) 4.22
Early health effects of the emerging tobacco epidemic in China. A 16-year prospective study. JAMA (1997) 4.09
Identification of the SV40 agnogene product: a DNA binding protein. Nature (1981) 3.80
Proposal for a new clinical entity, IgG4-positive multiorgan lymphoproliferative syndrome: analysis of 64 cases of IgG4-related disorders. Ann Rheum Dis (2008) 3.77
Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus. J Neurosci (1997) 3.49
Distinct actions of cis and trans ATP within the double ring of the chaperonin GroEL. Nature (1997) 3.48
Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia. J Med Genet (2004) 3.45
1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells. Proc Natl Acad Sci U S A (1994) 3.37
Maturational disturbance of chondrocytes in Cbfa1-deficient mice. Dev Dyn (1999) 3.33
Structure and function in GroEL-mediated protein folding. Annu Rev Biochem (1998) 3.18
Colorectal tumours and pit pattern. J Clin Pathol (1994) 3.01
Cloning of integrated Moloney sarcoma proviral DNA sequences in bacteriophage lambda. Proc Natl Acad Sci U S A (1979) 2.98
Simple, quantitative assay for both xenotropic murine leukemia and ecotropic feline leukemia viruses. J Virol (1974) 2.84
Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling. EMBO J (1994) 2.81
Familial gastrointestinal stromal tumours with germline mutation of the KIT gene. Nat Genet (1998) 2.80
Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication. J Virol (1996) 2.68
American ginseng (Panax quinquefolius L) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus. Arch Intern Med (2000) 2.67
Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients. J Clin Invest (1993) 2.64
Isolation of RD-114-like oncornavirus from a cat cell line. J Virol (1973) 2.61
Effect of c-kit mutation on prognosis of gastrointestinal stromal tumors. Cancer Res (1999) 2.61
Measuring circulating cell-derived microparticles. J Thromb Haemost (2004) 2.61
IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector. Mol Ther (2000) 2.59
An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls. Horm Metab Res (2000) 2.59
Decreased production of mast cells in S1/S1d anemic mice. Blood (1979) 2.53
Lipid-binding proteins: a family of fatty acid and retinoid transport proteins. Adv Protein Chem (1994) 2.53
Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. J Neurosci (1998) 2.48
Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity. Diabetes (1999) 2.47
Long-term results of balloon-occluded retrograde transvenous obliteration for the treatment of gastric varices and hepatic encephalopathy. J Vasc Interv Radiol (2001) 2.43
Cbfa1 is a positive regulatory factor in chondrocyte maturation. J Biol Chem (2000) 2.38
Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt. Mol Cell Biol (1999) 2.37
Interleukin 6 plays a key role in the development of antigen-induced arthritis. Proc Natl Acad Sci U S A (1998) 2.37
Biological and clinical review of stromal tumors in the gastrointestinal tract. Histol Histopathol (2000) 2.36
Enzymatic properties of de novo-type mouse DNA (cytosine-5) methyltransferases. Nucleic Acids Res (2001) 2.36
Transformation of mouse 3T3 cells by murine sarcoma virus: release of virus-like particles in the absence of replicating murine leukemia helper virus. Proc Natl Acad Sci U S A (1971) 2.26
A dynamic model for the allosteric mechanism of GroEL. J Mol Biol (2000) 2.20
Saxagliptin given in combination with metformin as initial therapy improves glycaemic control in patients with type 2 diabetes compared with either monotherapy: a randomized controlled trial. Diabetes Obes Metab (2009) 2.19
Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules. J Biol Chem (2001) 2.18
Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer. Br J Cancer (2008) 2.13
Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Proc Natl Acad Sci U S A (1995) 2.12
Predominance of T lymphocytes in pancreatic islets and spleen of pre-diabetic non-obese diabetic (NOD) mice: a longitudinal study. Clin Exp Immunol (1985) 2.12
Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain. Neurosci Lett (1993) 2.10
Genetically mast-cell-deficient W/Wv and Sl/Sld mice. Their value for the analysis of the roles of mast cells in biologic responses in vivo. Am J Pathol (1987) 2.05
Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn's disease. Gut (2005) 2.03
An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity. Cell (2000) 2.00
Interleukin 4 as an essential factor for in vitro clonal growth of murine connective tissue-type mast cells. J Exp Med (1987) 1.96
Upregulation of two death pathways of perforin/granzyme and FasL/Fas in septic acute respiratory distress syndrome. Am J Respir Crit Care Med (2000) 1.94
Role of alveolar macrophages in initiation and regulation of inflammation in Pseudomonas aeruginosa pneumonia. Infect Immun (1998) 1.92
Role of osteopontin in bone remodeling caused by mechanical stress. J Bone Miner Res (1999) 1.92
High incidence of ultraviolet-B-or chemical-carcinogen-induced skin tumours in mice lacking the xeroderma pigmentosum group A gene. Nature (1995) 1.91
High Fas ligand expression on lymphocytes in lesions of ulcerative colitis. Gut (1998) 1.88
Reactions of electron-deficient alkynes and allenes under phosphine catalysis. Acc Chem Res (2001) 1.86
Neurofilaments are obligate heteropolymers in vivo. J Cell Biol (1993) 1.82
Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer. Oncogene (2007) 1.81
Cell proliferative activity in intraductal papillary-mucinous neoplasms and invasive ductal adenocarcinomas of the pancreas: an immunohistochemical study. Arch Pathol Lab Med (1998) 1.81
Perceptual correlates of neural representations evoked by odorant enantiomers. J Neurosci (2001) 1.81
Impairment of hippocampal mossy fiber LTD in mice lacking mGluR2. Science (1996) 1.81
Distribution of targets for avian retrovirus DNA integration in vivo. Genes Dev (1994) 1.80
Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites. Neuroscience (2001) 1.80
Development of mast cells from grafted bone marrow cells in irradiated mice. Nature (1977) 1.78
A mouse model of a human multiple GIST family with KIT-Asp820Tyr mutation generated by a knock-in strategy. J Pathol (2008) 1.78
Reduced uptake of oxidized low density lipoproteins in monocyte-derived macrophages from CD36-deficient subjects. J Clin Invest (1995) 1.77
Depressed type of colorectal cancer. Endoscopy (1995) 1.77
bcl-2 deficiency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine. Cancer Res (1995) 1.75
Transcriptional regulation of osteopontin gene in vivo by PEBP2alphaA/CBFA1 and ETS1 in the skeletal tissues. Oncogene (1998) 1.70
DRBP76, a double-stranded RNA-binding nuclear protein, is phosphorylated by the interferon-induced protein kinase, PKR. J Biol Chem (1999) 1.70
Synergistic actions of antibacterial neutrophil defensins and cathelicidins. Inflamm Res (2000) 1.67
A truncated isoform of the PP2A B56 subunit promotes cell motility through paxillin phosphorylation. EMBO J (2000) 1.67
Genetic analysis of double-strand break repair in Escherichia coli. J Bacteriol (1993) 1.65
Peroxisome proliferator-activated receptor gamma induces growth arrest and differentiation markers of human colon cancer cells. Jpn J Cancer Res (1999) 1.63
Preoperative drainage using a transanal tube enables elective laparoscopic colectomy for obstructive distal colorectal cancer. Endoscopy (2013) 1.60
Non-invasive pulsed cavitational ultrasound for fetal tissue ablation: feasibility study in a fetal sheep model. Ultrasound Obstet Gynecol (2011) 1.59
Expression of inducible nitric oxide synthase and inflammatory cytokines in alveolar macrophages of ARDS following sepsis. Chest (1998) 1.59
Revertants of mouse cells transformed by murine sarcoma virus. I. Characterization of flat and transformed sublines without a rescuable murine sarcoma virus. Virology (1972) 1.59
Deficiency of c-kit+ cells in patients with a myopathic form of chronic idiopathic intestinal pseudo-obstruction. Am J Gastroenterol (1997) 1.58
PapD chaperone function in pilus biogenesis depends on oxidant and chaperone-like activities of DsbA. Proc Natl Acad Sci U S A (1994) 1.58