Published in Gut on June 01, 2005
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature (2008) 10.84
Mesenteric fat as a source of C reactive protein and as a target for bacterial translocation in Crohn's disease. Gut (2011) 2.87
A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease. Autophagy (2009) 1.81
Mesenteric fat in Crohn's disease: a pathogenetic hallmark or an innocent bystander? Gut (2006) 1.34
Pathophysiological significance of adiponectin. Med Mol Morphol (2007) 1.18
The peroxisome proliferator-activated receptor gamma agonist rosiglitazone ameliorates murine lupus by induction of adiponectin. J Immunol (2009) 1.17
Creeping fat in Crohn's disease: travelling in a creeper lane of research? Gut (2005) 1.09
Where are all the Mycobacterium avium subspecies paratuberculosis in patients with Crohn's disease? PLoS Pathog (2009) 1.02
Adipose tissue and inflammatory bowel disease pathogenesis. Inflamm Bowel Dis (2012) 0.98
T-lymphocyte responses to intestinally absorbed antigens can contribute to adipose tissue inflammation and glucose intolerance during high fat feeding. PLoS One (2010) 0.93
Association of low serum adiponectin levels with erosive esophagitis in men: an analysis of 2405 subjects undergoing physical check-ups. J Gastroenterol (2011) 0.91
Extraluminal factors contributing to inflammatory bowel disease. World J Gastroenterol (2011) 0.87
Serum levels and mesenteric fat tissue expression of adiponectin and leptin in patients with Crohn's disease. Clin Exp Immunol (2012) 0.86
The role of physical exercise in inflammatory bowel disease. Biomed Res Int (2014) 0.84
Predictors of Thiopurine Treatment Failure in Biologic-Naïve Ulcerative Colitis Patients. Dig Dis Sci (2015) 0.84
Serum adipokines in inflammatory bowel disease. World J Gastroenterol (2014) 0.84
Metabolic syndrome frequency in inflammatory bowel diseases. Saudi J Gastroenterol (2011) 0.84
Prevalence of metabolic syndrome is comparable between inflammatory bowel disease patients and the general population. J Gastroenterol (2010) 0.83
Adiponectin deficiency does not affect development and progression of spontaneous colitis in IL-10 knockout mice. Am J Physiol Gastrointest Liver Physiol (2008) 0.83
Dysregulation of maternal serum adiponectin in preterm labor. J Matern Fetal Neonatal Med (2009) 0.83
Toll-like receptor 4, F4/80 and pro-inflammatory cytokines in intestinal and mesenteric fat tissue of Crohn's disease. Int J Clin Exp Med (2013) 0.82
Neuropeptides, mesenteric fat, and intestinal inflammation. Ann N Y Acad Sci (2008) 0.82
Adiponectin deficiency modulates adhesion molecules expression and cytokine production but does not affect disease severity in the transfer model of colitis. Cytokine (2009) 0.81
Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1. Am J Physiol Gastrointest Liver Physiol (2015) 0.81
Circulating ghrelin levels and obestatin/ghrelin ratio as a marker of activity in ulcerative colitis. Intest Res (2015) 0.81
Differential effects of energy balance on experimentally-induced colitis. World J Gastroenterol (2012) 0.80
Study of adiponectin in chronic liver disease and cholestasis. Hepatol Int (2010) 0.80
Visceral fat as a useful parameter in the differential diagnosis of Crohn's disease and intestinal tuberculosis. Intest Res (2014) 0.80
Substance P, obesity, and gut inflammation. Curr Opin Endocrinol Diabetes Obes (2009) 0.80
'Nodophagy': New crossroads in Crohn disease pathogenesis. Gut Microbes (2010) 0.79
Body Mass Index, Genetic Susceptibility, and Risk of Complications Among Individuals with Crohn's Disease. Inflamm Bowel Dis (2015) 0.78
Apoptosis and inflammation: role of adipokines in inflammatory bowel disease. Clin Transl Gastroenterol (2010) 0.78
Bacterial translocation - impact on the adipocyte compartment. Front Immunol (2014) 0.78
Inflammatory cytokine gene expression in mesenteric adipose tissue during acute experimental colitis. PLoS One (2013) 0.78
Subcutaneous adipose tissue fatty acid desaturation in adults with and without rare adipose disorders. Lipids Health Dis (2012) 0.78
Adipokines and the role of visceral adipose tissue in inflammatory bowel disease. Ann Gastroenterol (2016) 0.78
Interaction of obesity and inflammatory bowel disease. World J Gastroenterol (2016) 0.77
Defective apoptosis in intestinal and mesenteric adipose tissue of Crohn's disease patients. PLoS One (2014) 0.77
Transcriptional and Molecular Pathways Activated in Mesenteric Adipose Tissue and Intestinal Mucosa of Crohn's Disease Patients. Int J Inflam (2017) 0.76
Melatonin modulates adiponectin expression on murine colitis with sleep deprivation. World J Gastroenterol (2016) 0.76
Blockade of Sphingosine 1-Phosphate Receptor 2 Signaling Attenuates High-Fat Diet-Induced Adipocyte Hypertrophy and Systemic Glucose Intolerance in Mice. Endocrinology (2016) 0.76
Obesity in IBD: epidemiology, pathogenesis, disease course and treatment outcomes. Nat Rev Gastroenterol Hepatol (2016) 0.75
Beneficial Effect of Voluntary Exercise on Experimental Colitis in Mice Fed a High-Fat Diet: The Role of Irisin, Adiponectin and Proinflammatory Biomarkers. Nutrients (2017) 0.75
Obesity is Associated With Poor Surgical Outcome in Crohn's Disease. Gastroenterology Res (2013) 0.75
Obesity and Outcome of Crohn's Associated Perianal Fistula Surgery: A Case-Control Study. Gastroenterology Res (2015) 0.75
Association of medications for lifestyle-related diseases with reflux esophagitis. Ther Clin Risk Manag (2016) 0.75
Body Mass Index Is Associated With Mucosal Disease in Crohn's: Results of a Case-Control Study. Gastroenterology Res (2014) 0.75
Retinol Binding Protein 4 in children with Inflammatory Bowel Disease: a negative correlation with the disease activity. Hippokratia (2012) 0.75
Are adipocytokines inflammatory or metabolic mediators in patients with inflammatory bowel disease? Ther Clin Risk Manag (2017) 0.75
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med (2001) 16.51
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun (1999) 14.25
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell (1995) 11.72
Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab (2001) 9.53
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat Med (2002) 8.95
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell (1995) 7.99
Interleukin-6 and the acute phase response. Biochem J (1990) 7.97
Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation (2000) 6.96
cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). Biochem Biophys Res Commun (1996) 5.40
Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation (2000) 5.36
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest (2003) 5.32
PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes (2001) 5.18
Adipogenesis and obesity: rounding out the big picture. Cell (1996) 5.15
Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation (2001) 4.82
Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis. J Biol Chem (2002) 4.16
Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation (2002) 3.81
Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J Clin Invest (1998) 3.76
Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue. Circulation (2003) 3.73
Collectins: collagenous C-type lectins of the innate immune defense system. Immunol Today (1994) 2.81
Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization. Endocrinology (2002) 2.72
The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance. J Biol Chem (2001) 2.69
Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages. Circulation (2004) 2.58
Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin. Gastroenterology (2003) 2.53
Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell. Circulation (2002) 2.40
Adiponectin differentially regulates cytokines in porcine macrophages. Biochem Biophys Res Commun (2004) 2.32
Overexpression of leptin mRNA in mesenteric adipose tissue in inflammatory bowel diseases. Gastroenterol Clin Biol (2003) 2.26
15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes. J Biol Chem (2002) 2.04
Inflammatory alterations in mesenteric adipose tissue in Crohn's disease. Gastroenterology (1999) 1.68
The collectins in innate immunity. Curr Opin Immunol (1996) 1.46
Fat-wrapping in Crohn's disease: pathological basis and relevance to surgical practice. Br J Surg (1992) 1.36
C-reactive protein levels as a direct indicator of interleukin-6 levels in humans in vivo. Arthritis Rheum (1992) 1.29
Vascular changes in Crohn's disease. Am J Roentgenol Radium Ther Nucl Med (1968) 1.18
Intraoperative enteroscopy in Crohn's disease. Br J Surg (1993) 1.14
Regulation of tumour necrosis factor-alpha release from human adipose tissue in vitro. J Endocrinol (1999) 1.04
Fibrofatty proliferation of the mesentery in Crohn disease. Abdom Imaging (1998) 0.94
Peroxisome proliferator-activated receptor gamma and the control of adipogenesis. Curr Opin Lipidol (1997) 0.92
The relationship between inflammatory and serosal connective tissue changes in ileal Crohn's disease: evidence for a possible causative link. J Pathol (2000) 0.92
Collectins: collectors of microorganisms for the innate immune system. Bioessays (1997) 0.92
Recognition of regional ileitis in the operating room. Dis Colon Rectum (1971) 0.89
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science (1998) 21.13
Whole genome sequencing of meticillin-resistant Staphylococcus aureus. Lancet (2001) 18.55
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun (1999) 14.25
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med (1996) 13.49
Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc Natl Acad Sci U S A (1996) 12.92
Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy (2008) 12.35
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol (2000) 9.85
A new class of genetic element, staphylococcus cassette chromosome mec, encodes methicillin resistance in Staphylococcus aureus. Antimicrob Agents Chemother (2000) 9.84
Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab (2001) 9.53
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. Genes Dev (2000) 9.09
Characterization of avian H5N1 influenza viruses from poultry in Hong Kong. Virology (1998) 7.99
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J Clin Invest (1996) 7.93
The emergence and evolution of methicillin-resistant Staphylococcus aureus. Trends Microbiol (2001) 7.73
Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1. DNA Res (1999) 7.39
Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation (2000) 6.96
Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3. DNA Res (1998) 6.79
Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J Clin Invest (1997) 6.16
cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). Biochem Biophys Res Commun (1996) 5.40
Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation (2000) 5.36
Biological heterogeneity, including systemic replication in mice, of H5N1 influenza A virus isolates from humans in Hong Kong. J Virol (1999) 5.21
PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes (2001) 5.18
Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice. Proc Natl Acad Sci U S A (1998) 4.89
Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation (2001) 4.82
Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2. J Clin Invest (1998) 4.78
Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene. J Clin Invest (1997) 4.75
A novel subtype of type 1 diabetes mellitus characterized by a rapid onset and an absence of diabetes-related antibodies. Osaka IDDM Study Group. N Engl J Med (2000) 4.73
A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations. Br J Cancer (2006) 4.46
Diagnosis of colorectal tumorous lesions by magnifying endoscopy. Gastrointest Endosc (1996) 4.33
Standard steroid treatment for autoimmune pancreatitis. Gut (2009) 4.33
Abdominal fat: standardized technique for measurement at CT. Radiology (1999) 4.25
Potential for transmission of avian influenza viruses to pigs. J Gen Virol (1994) 4.24
Affective picture processing: the late positive potential is modulated by motivational relevance. Psychophysiology (2000) 3.84
CD36 deficiency associated with insulin resistance. Lancet (2001) 3.82
Proposal for a new clinical entity, IgG4-positive multiorgan lymphoproliferative syndrome: analysis of 64 cases of IgG4-related disorders. Ann Rheum Dis (2008) 3.77
Generalized-ensemble algorithms for molecular simulations of biopolymers. Biopolymers (2001) 3.69
Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes (2001) 3.61
SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation. Genes Dev (2001) 3.52
Embolization of arteriovenous malformations with Onyx: clinicopathological experience in 23 patients. Neurosurgery (2001) 3.49
Genetic organization of the chromosome region surrounding mecA in clinical staphylococcal strains: role of IS431-mediated mecI deletion in expression of resistance in mecA-carrying, low-level methicillin-resistant Staphylococcus haemolyticus. Antimicrob Agents Chemother (2001) 3.39
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc Natl Acad Sci U S A (1998) 3.35
Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity. Metabolism (1987) 3.32
The role of influenza A virus hemagglutinin residues 226 and 228 in receptor specificity and host range restriction. J Virol (1998) 3.25
Sialic acid species as a determinant of the host range of influenza A viruses. J Virol (2000) 3.10
Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide. Leukemia (2012) 3.04
Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat Med (1996) 3.02
A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel. J Biol Chem (1996) 2.99
Epidemiology, enteropathogenicity, and classification of Vi.rio parahaemolyticus. J Infect Dis (1965) 2.84
Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase. Nat Genet (1999) 2.81
Atypical adenomatous hyperplasia of the lung. Implications for the pathogenesis of peripheral lung adenocarcinoma. Am J Clin Pathol (1999) 2.81
Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. J Clin Endocrinol Metab (2001) 2.73
Expression of immunoreactive E-cadherin adhesion molecules in human cancers. Am J Pathol (1991) 2.71
Demonstration of diastolic and presystolic Purkinje potentials as critical potentials in a macroreentry circuit of verapamil-sensitive idiopathic left ventricular tachycardia. J Am Coll Cardiol (2000) 2.67
Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients. J Clin Invest (1993) 2.64
Effect of c-kit mutation on prognosis of gastrointestinal stromal tumors. Cancer Res (1999) 2.61
Transmission of bacteriocinogenicity by conjugation in group D streptococci. Jpn J Microbiol (1973) 2.60
An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls. Horm Metab Res (2000) 2.59
Sterol regulatory element-binding proteins: activators of cholesterol and fatty acid biosynthesis. Curr Opin Lipidol (1999) 2.54
Impact of sarcopenia on survival in patients undergoing living donor liver transplantation. Am J Transplant (2013) 2.51
Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity. Diabetes (1999) 2.47
Molecular mechanism of metabolic syndrome X: contribution of adipocytokines adipocyte-derived bioactive substances. Ann N Y Acad Sci (1999) 2.44
Natural history of the neck remnant of a cerebral aneurysm treated with the Guglielmi detachable coil system. J Neurosurg (2000) 2.38
CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins. Blood (1997) 2.37
New retraction technique to allow better visualization of Calot's triangle during laparoscopic cholecystectomy. Surg Endosc (1998) 2.35
Cross-coupling reactions of potassium alkyltrifluoroborates with aryl and 1-alkenyl trifluoromethanesulfonates. Org Lett (2001) 2.28
Angiographic no-reflow phenomenon as a predictor of adverse long-term outcome in patients treated with percutaneous transluminal coronary angioplasty for first acute myocardial infarction. J Am Coll Cardiol (2000) 2.20
Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. J Allergy Clin Immunol (2012) 2.17
A recombinant hepatitis C virus RNA-dependent RNA polymerase capable of copying the full-length viral RNA. J Virol (1999) 2.16
Ectodomain shedding of epidermal growth factor receptor ligands is required for keratinocyte migration in cutaneous wound healing. J Cell Biol (2000) 2.14
Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer. Br J Cancer (2008) 2.13