S J Parsons

Author PubWeight™ 84.74‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function. J Biol Chem 1999 3.91
2 Mechanism of biological synergy between cellular Src and epidermal growth factor receptor. Proc Natl Acad Sci U S A 1999 3.43
3 Monoclonal antibodies to Rous sarcoma virus pp60src react with enzymatically active cellular pp60src of avian and mammalian origin. J Virol 1984 3.18
4 A 42-kD tyrosine kinase substrate linked to chromaffin cell secretion exhibits an associated MAP kinase activity and is highly related to a 42-kD mitogen-stimulated protein in fibroblasts. J Cell Biol 1990 2.41
5 Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers. Proc Natl Acad Sci U S A 1995 2.29
6 Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer. Breast Cancer Res 2000 2.14
7 c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation. J Cell Biol 1995 2.06
8 Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways. Curr Opin Cell Biol 1997 1.97
9 Src family kinases and HER2 interactions in human breast cancer cell growth and survival. Oncogene 2001 1.89
10 Transmission of hepatitis C within Australian prisons. Med J Aust 1999 1.89
11 A strategy for reducing blood-transfusion requirements in elective orthopaedic surgery. Audit of an algorithm for arthroplasty of the lower limb. J Bone Joint Surg Br 2003 1.78
12 c-Src, receptor tyrosine kinases, and human cancer. Adv Cancer Res 1999 1.71
13 c-Src modulates ErbB2 and ErbB3 heterocomplex formation and function. Oncogene 2006 1.69
14 p60c-src activity detected in the chromaffin granule membrane. Biochem Biophys Res Commun 1986 1.62
15 Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src. Mol Cell Biol 1988 1.59
16 pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src. Mol Cell Biol 1989 1.56
17 Local degradation of fibronectin at sites of expression of the transforming gene product pp60src. Nature 1985 1.55
18 Characterization of human epidermal growth factor receptor and c-Src interactions in human breast tumor cells. Mol Carcinog 1998 1.54
19 Purification and properties of beta-isopropylmalate dehydrogenase. J Biol Chem 1969 1.41
20 Interleukin-6- and cyclic AMP-mediated signaling potentiates neuroendocrine differentiation of LNCaP prostate tumor cells. Mol Cell Biol 2001 1.41
21 Acquisition of neuroendocrine characteristics by prostate tumor cells is reversible: implications for prostate cancer progression. Cancer Res 1999 1.37
22 Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation. Mol Cell Biol 1998 1.32
23 Isolation and partial characterization of a monoclonal antibody to the Rous sarcoma virus transforming protein pp60src. J Virol 1983 1.31
24 Role of c-Src tyrosine kinase in EGF-induced mitogenesis. Front Biosci 1997 1.28
25 Identification of chromaffin granule-binding proteins. Relationship of the chromobindins to calelectrin, synhibin, and the tyrosine kinase substrates p35 and p36. J Biol Chem 1987 1.27
26 Overexpression of cellular Src in fibroblasts enhances endocytic internalization of epidermal growth factor receptor. J Biol Chem 1997 1.22
27 Effect of butyrolactone I on the producing fungus, Aspergillus terreus. Appl Environ Microbiol 1998 1.21
28 Localization of conserved and nonconserved epitopes within the Rous sarcoma virus-encoded src protein. J Virol 1986 1.19
29 Phosphorylation of p190 on Tyr1105 by c-Src is necessary but not sufficient for EGF-induced actin disassembly in C3H10T1/2 fibroblasts. J Cell Sci 2001 1.14
30 Neurotensin stimulates mitogenesis of prostate cancer cells through a novel c-Src/Stat5b pathway. Oncogene 2006 1.14
31 Identification and characterization of a cytoskeleton-associated, epidermal growth factor sensitive pp60c-src substrate. Oncogene 1992 1.14
32 Partial purification of a mitogen-activated protein kinase kinase activator from bovine brain. Identification as B-Raf or a B-Raf-associated activity. J Biol Chem 1994 1.12
33 Increased levels of p21ras-GTP and enhanced DNA synthesis accompany elevated tyrosyl phosphorylation of GAP-associated proteins, p190 and p62, in c-src overexpressors. Oncogene 1993 1.12
34 Immune response to the src gene product in mice bearing tumors induced by injection of avian sarcoma virus-transformed mouse cells. J Virol 1979 1.11
35 Activation of pp60c-src tyrosine kinase specific activity in tumor-derived Syrian hamster embryo cells. Oncogene 1988 1.10
36 Tyrosine phosphorylation of G protein alpha subunits by pp60c-src. Proc Natl Acad Sci U S A 1992 1.10
37 The sites of phosphorylation by protein kinase C and an intact SH2 domain are required for the enhanced response to beta-adrenergic agonists in cells overexpressing c-src. Mol Cell Biol 1993 1.06
38 A protein that is highly related to GTPase-activating protein-associated p62 complexes with phospholipase C gamma. Mol Cell Biol 1994 1.05
39 Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferation. Oncogene 2011 1.02
40 Overexpression of c-src enhances beta-adrenergic-induced cAMP accumulation. Proc Natl Acad Sci U S A 1990 1.01
41 Two SH2 domains of p120 Ras GTPase-activating protein bind synergistically to tyrosine phosphorylated p190 Rho GTPase-activating protein. J Biol Chem 1995 0.96
42 Electroconvulsive treatment induces a rapid and transient increase in tyrosine phosphorylation of a 40-kilodalton protein associated with microtubule-associated protein 2 kinase activity. J Neurochem 1991 0.96
43 c-Src tyrosine phosphorylation of epidermal growth factor receptor, P190 RhoGAP, and focal adhesion kinase regulates diverse cellular processes. Chem Rev 2001 0.95
44 Activated 3',5'-cyclic AMP-dependent protein kinase is sufficient to induce neuroendocrine-like differentiation of the LNCaP prostate tumor cell line. J Biol Chem 2000 0.94
45 Gonadotropin-releasing hormone pulses are required to maintain activation of mitogen-activated protein kinase: role in stimulation of gonadotrope gene expression. Endocrinology 1998 0.93
46 Enhanced EGF mitogenic response is associated with enhanced tyrosine phosphorylation of specific cellular proteins in fibroblasts overexpressing c-src. Oncogene 1990 0.93
47 Analysis of P210bcr-abl tyrosine protein kinase activity in various subtypes of Philadelphia chromosome-positive cells from chronic myelogenous leukemia patients. Cancer Res 1987 0.93
48 Monoclonal antibodies to oncoproteins. Methods Enzymol 1995 0.92
49 Monoclonal antibodies specific for the virion polypeptide, p27, of avian retroviruses. Hybridoma 1984 0.87
50 Matrix mineralization in hypertrophic chondrocyte cultures. Beta glycerophosphate increases type X collagen messenger RNA and the specific activity of pp60c-src kinase. Bone Miner 1992 0.87
51 Tyrosine kinases are required for catecholamine secretion and mitogen-activated protein kinase activation in bovine adrenal chromaffin cells. J Neurochem 1996 0.87
52 Modulation of pp60c-src tyrosine kinase activity during secretion in stimulated bovine adrenal chromaffin cells. J Neurosci Res 1989 0.86
53 Reduced tyrosine kinase specific activity is associated with hypophosphorylation of pp60c-src in cells infected with avian erythroblastosis virus. Proc Natl Acad Sci U S A 1987 0.85
54 Roles for protein kinase C and mitogen-activated protein kinase in nicotine-induced secretion from bovine adrenal chromaffin cells. J Neurochem 1997 0.84
55 Inhibition of the tyrosine kinase activity of v-src, v-fgr, and v-yes gene products by a monoclonal antibody which binds both amino and carboxy peptide fragments of pp60v-src. J Virol 1987 0.84
56 Overexpression of pp60c-src is associated with altered regulation of adenylyl cyclase. Cell Signal 1992 0.84
57 Tyrosine 807 of the v-Fms oncogene product controls cell morphology and association with p120RasGAP. J Virol 1995 0.83
58 Activation of Fyn tyrosine kinase upon secretagogue stimulation of bovine chromaffin cells. J Neurosci Res 1996 0.83
59 pp60c-src enhances the acetylcholine receptor-dependent catecholamine release in vaccinia virus-infected bovine adrenal chromaffin cells. J Neurochem 1994 0.81
60 Structural and functional motifs of the Rous sarcoma virus src protein. Gene Amplif Anal 1986 0.80
61 Phosphorylation of the p190 RhoGAP N-terminal domain by c-Src results in a loss of GTP binding activity. FEBS Lett 2000 0.80
62 Phosphotyrosine phosphatase activity associated with c-Src in large multimeric complexes isolated from adrenal medullary chromaffin cells. Biochem J 1997 0.79
63 Insulin and phorbol ester induce distinct phosphorylations of pp60c-src in the BC3H-1 murine myocyte cell line. Oncogene 1989 0.78
64 Identification of the in vitro phosphorylation sites on Gs alpha mediated by pp60c-src. Biochem J 1995 0.76
65 Fidelity of initiation of protein synthesis after premature chain termination in polarity mutants. J Bacteriol 1969 0.75
66 A novel negative imaging technique for accurate localization of stainable proteins on complex two-dimensional autoradiograms. Electrophoresis 1997 0.75
67 Protein-tyrosine kinases, oncogenes, and cancer. Important Adv Oncol 1993 0.75