Published in Biophys J on June 01, 1995
Gating and regulation of connexin 43 (Cx43) hemichannels. Proc Natl Acad Sci U S A (2003) 2.79
Gap junction channel gating. Biochim Biophys Acta (2004) 2.34
Gap junctions. Cold Spring Harb Perspect Biol (2009) 2.27
New roles for astrocytes: gap junction hemichannels have something to communicate. Trends Neurosci (2003) 2.25
Stoichiometry of transjunctional voltage-gating polarity reversal by a negative charge substitution in the amino terminus of a connexin32 chimera. J Gen Physiol (2000) 2.23
The first extracellular loop domain is a major determinant of charge selectivity in connexin46 channels. Biophys J (2000) 2.20
Molecular determinants of electrical rectification of single channel conductance in gap junctions formed by connexins 26 and 32. J Gen Physiol (1999) 2.16
Gating properties of gap junction channels assembled from connexin43 and connexin43 fused with green fluorescent protein. Biophys J (2001) 2.15
The permeability of gap junction channels to probes of different size is dependent on connexin composition and permeant-pore affinities. Biophys J (2004) 1.98
Coupling asymmetry of heterotypic connexin 45/ connexin 43-EGFP gap junctions: properties of fast and slow gating mechanisms. Proc Natl Acad Sci U S A (2002) 1.71
Quinine blocks specific gap junction channel subtypes. Proc Natl Acad Sci U S A (2001) 1.67
Two distinct gating mechanisms in gap junction channels: CO2-sensitive and voltage-sensitive. Biophys J (1997) 1.61
Gap junctions. Compr Physiol (2012) 1.59
Intercellular communication in spinal cord astrocytes: fine tuning between gap junctions and P2 nucleotide receptors in calcium wave propagation. J Neurosci (2000) 1.56
Functional properties of mouse connexin30.2 expressed in the conduction system of the heart. Circ Res (2005) 1.54
Formation of heteromeric gap junction channels by connexins 40 and 43 in vascular smooth muscle cells. Proc Natl Acad Sci U S A (1999) 1.53
Properties of two cataract-associated mutations located in the NH2 terminus of connexin 46. Am J Physiol Cell Physiol (2013) 1.46
Biophysical properties of connexin-45 gap junction hemichannels studied in vertebrate cells. J Gen Physiol (2002) 1.46
Voltage dependence of macroscopic and unitary currents of gap junction channels formed by mouse connexin50 expressed in rat neuroblastoma cells. J Physiol (1999) 1.46
Differentially altered Ca2+ regulation and Ca2+ permeability in Cx26 hemichannels formed by the A40V and G45E mutations that cause keratitis ichthyosis deafness syndrome. J Gen Physiol (2010) 1.45
Conductance and permeability of the residual state of connexin43 gap junction channels. J Gen Physiol (2002) 1.41
Gating properties of heterotypic gap junction channels formed of connexins 40, 43, and 45. Biophys J (2006) 1.40
Amino terminal glutamate residues confer spermine sensitivity and affect voltage gating and channel conductance of rat connexin40 gap junctions. J Physiol (2004) 1.37
Loop gating of connexin hemichannels involves movement of pore-lining residues in the first extracellular loop domain. J Biol Chem (2008) 1.36
Gap junction channels and cardiac impulse propagation. J Membr Biol (2007) 1.29
Properties of gap junction channels formed by Cx46 alone and in combination with Cx50. Biophys J (2000) 1.24
Functional role of the carboxyl terminal domain of human connexin 50 in gap junctional channels. J Membr Biol (2002) 1.24
Biophysical properties of mouse connexin30 gap junction channels studied in transfected human HeLa cells. J Physiol (1999) 1.20
Connexin30.2 containing gap junction channels decelerate impulse propagation through the atrioventricular node. Proc Natl Acad Sci U S A (2006) 1.17
Permeability of homotypic and heterotypic gap junction channels formed of cardiac connexins mCx30.2, Cx40, Cx43, and Cx45. Am J Physiol Heart Circ Physiol (2007) 1.17
Mathematical model of vertebrate gap junctions derived from electrical measurements on homotypic and heterotypic channels. J Physiol (1998) 1.16
Interstitial volume modulates the conduction velocity-gap junction relationship. Am J Physiol Heart Circ Physiol (2011) 1.16
A stochastic four-state model of contingent gating of gap junction channels containing two "fast" gates sensitive to transjunctional voltage. Biophys J (2009) 1.14
Influence of dynamic gap junction resistance on impulse propagation in ventricular myocardium: a computer simulation study. Biophys J (2001) 1.12
Gap junction channel gating modulated through protein phosphorylation. Prog Biophys Mol Biol (2007) 1.12
Regulation of ventral surface CO2/H+-sensitive neurons by purinergic signalling. J Physiol (2012) 1.12
Connexin-mediated cardiac impulse propagation: connexin 30.2 slows atrioventricular conduction in mouse heart. Trends Cardiovasc Med (2006) 1.10
Effect of membrane tension on gap junctional conductance of supporting cells in Corti's organ. J Gen Physiol (1998) 1.06
Electrophysiological remodeling in heart failure. J Mol Cell Cardiol (2010) 1.05
A transient diffusion model yields unitary gap junctional permeabilities from images of cell-to-cell fluorescent dye transfer between Xenopus oocytes. Biophys J (2004) 1.05
Determinants of myocardial conduction velocity: implications for arrhythmogenesis. Front Physiol (2013) 1.01
Functional alterations in gap junction channels formed by mutant forms of connexin 32: evidence for loss of function as a pathogenic mechanism in the X-linked form of Charcot-Marie-Tooth disease. Brain Res (2001) 1.00
Structural basis for the selective permeability of channels made of communicating junction proteins. Biochim Biophys Acta (2012) 0.97
Stochastic 16-state model of voltage gating of gap-junction channels enclosing fast and slow gates. Biophys J (2012) 0.97
Autocrine ATP release coupled to extracellular pyrophosphate accumulation in vascular smooth muscle cells. Am J Physiol Cell Physiol (2009) 0.93
Electrophysiological properties of electrical synapses between rat sympathetic preganglionic neurones in vitro. J Physiol (1999) 0.93
Nature of plasmalemmal functional "hemichannels". Biochim Biophys Acta (2011) 0.93
Biophysical properties of heterotypic gap junctions newly formed between two types of insect cells. J Physiol (1997) 0.93
The role of amino terminus of mouse Cx50 in determining transjunctional voltage-dependent gating and unitary conductance. Biophys J (2010) 0.90
Selective inhibition of gap junction channel activity by synthetic peptides. J Physiol (1999) 0.86
Aberrant Cx26 hemichannels and keratitis-ichthyosis-deafness syndrome: insights into syndromic hearing loss. Front Cell Neurosci (2014) 0.86
The electrical behaviour of rat connexin46 gap junction channels expressed in transfected HeLa cells. Pflugers Arch (2003) 0.85
Aspartic acid residue D3 critically determines Cx50 gap junction channel transjunctional voltage-dependent gating and unitary conductance. Biophys J (2012) 0.83
Do connexin channels have a residual conductance state? Biophys J (1996) 0.81
Residual Cx45 and its relationship to Cx43 in murine ventricular myocardium. Channels (Austin) (2011) 0.79
Distribution and functional relevance of connexins in renin-producing cells. Pflugers Arch (2012) 0.78
Subconductance states of Cx30 gap junction channels: data from transfected HeLa cells versus data from a mathematical model. Biophys J (2006) 0.78
Charge at the 46th residue of connexin 50 is crucial for the gap-junctional unitary conductance and transjunctional voltage-dependent gating. J Physiol (2014) 0.78
Heterotypic connexin50/connexin50 mutant gap junction channels reveal interactions between two hemichannels during transjunctional voltage-dependent gating. J Physiol (2012) 0.78
CO(2) sensitivity of voltage gating and gating polarity of gapjunction channels--connexin40 and its COOH-terminus-truncated mutant. J Membr Biol (2004) 0.78
Non-stationary fluctuation analysis of macroscopic gap junction channel records. J Membr Biol (2005) 0.76
The connexin46 mutant, Cx46T19M, causes loss of gap junction function and alters hemi-channel gating. J Membr Biol (2014) 0.76
Stochastic Model of Gap Junctions Exhibiting Rectification and Multiple Closed States of Slow Gates. Biophys J (2016) 0.76
Reverberation of excitation in neuronal networks interconnected through voltage-gated gap junction channels. J Gen Physiol (2016) 0.76
Altered conductance and permeability of Cx40 mutations associated with atrial fibrillation. J Gen Physiol (2015) 0.75
Regulation of Cx45 hemichannels mediated by extracellular and intracellular calcium. Pflugers Arch (2012) 0.75
Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications. Pharmacol Rev (2017) 0.75
Differential phosphorylation of the gap junction protein connexin43 in junctional communication-competent and -deficient cell lines. J Cell Biol (1990) 3.32
Hemi-gap-junction channels in solitary horizontal cells of the catfish retina. J Physiol (1992) 2.40
Connexin40, a component of gap junctions in vascular endothelium, is restricted in its ability to interact with other connexins. Mol Biol Cell (1993) 2.14
Gap junction channels: distinct voltage-sensitive and -insensitive conductance states. Biophys J (1994) 1.99
Connexin37 forms high conductance gap junction channels with subconductance state activity and selective dye and ionic permeabilities. Biophys J (1994) 1.95
Identification of a proline residue as a transduction element involved in voltage gating of gap junctions. Nature (1993) 1.79
Biophysics of gap junctions. Semin Cell Biol (1992) 1.76
Immunochemical and electrophysiological characterization of murine connexin40 and -43 in mouse tissues and transfected human cells. Eur J Cell Biol (1994) 1.69
The spatial distribution and relative abundance of gap-junctional connexin40 and connexin43 correlate to functional properties of components of the cardiac atrioventricular conduction system. J Cell Sci (1993) 1.65
Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping. J Biol Chem (1992) 1.51
Molecular cloning and functional expression of mouse connexin40, a second gap junction gene preferentially expressed in lung. J Cell Biol (1992) 1.49
Cardiac myocytes express multiple gap junction proteins. Circ Res (1992) 1.46
Multiple conductance states of newly formed single gap junction channels between insect cells. Pflugers Arch (1993) 1.41
Gap junction protein connexin40 is preferentially expressed in vascular endothelium and conductive bundles of rat myocardium and is increased under hypertensive conditions. Circ Res (1993) 1.35
Restricted distribution of connexin40, a gap junctional protein, in mammalian heart. Circ Res (1994) 1.34
Electrical properties of the nexal membrane studied in rat ventricular cell pairs. J Physiol (1986) 1.33
Gap junction channels of insects exhibit a residual conductance. Pflugers Arch (1993) 1.33
Multiple-channel conductance states and voltage regulation of embryonic chick cardiac gap junctions. J Membr Biol (1992) 1.32
Gating characteristics of a steeply voltage-dependent gap junction channel in rat Schwann cells. J Gen Physiol (1993) 1.25
Electrical coupling between cells of the insect Aedes albopictus. J Physiol (1992) 1.20
Molecular cloning and expression of rat connexin40, a gap junction protein expressed in vascular smooth muscle. J Membr Biol (1992) 1.19
Biophysical characterization of gap-junction channels in HeLa cells. Pflugers Arch (1993) 1.12
Cytoplasmic bridges and gap junctions in an insect cell line (Aedes albopictus). Exp Physiol (1992) 1.11
Temperature dependence of gap junction properties in neonatal rat heart cells. Pflugers Arch (1993) 1.02
Immunoelectron microscopic visualization of the gap junction protein connexin 40 in the mammalian heart. Eur J Morphol (1993) 0.83
hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo. Genesis (2001) 6.29
Role of calcium ions in transient inward currents and aftercontractions induced by strophanthidin in cardiac Purkinje fibres. J Physiol (1978) 4.72
Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells. J Cell Biol (1995) 4.08
Transfer of the human gene for hypoxanthine-guanine phosphoribosyltransferase via isolated human metaphase chromosomes into mouse L-cells. Proc Natl Acad Sci U S A (1975) 3.91
Ionic basis of transient inward current induced by strophanthidin in cardiac Purkinje fibres. J Physiol (1978) 2.94
Cotransfer of two linked human genes into cultured mouse cells. Proc Natl Acad Sci U S A (1976) 2.93
Two homologous protein components of hepatic gap junctions. Nature (1987) 2.39
Abnormal cardiac conduction and morphogenesis in connexin40 and connexin43 double-deficient mice. Circ Res (2000) 2.37
Differential expression of three gap junction proteins in developing and mature brain tissues. Proc Natl Acad Sci U S A (1989) 2.34
Free magnesium in sheep, ferret and frog striated muscle at rest measured with ion-selective micro-electrodes. J Physiol (1982) 2.17
Comparative characterization of the 21-kD and 26-kD gap junction proteins in murine liver and cultured hepatocytes. J Cell Biol (1989) 2.11
Unique and shared functions of different connexins in mice. Curr Biol (2000) 2.10
Voltage-dependent gating of single gap junction channels in an insect cell line. Biophys J (1994) 2.05
Coupled transport of citrate and magnesium in Bacillus subtilis. J Biol Chem (1973) 1.87
Gap junctions in several tissues share antigenic determinants with liver gap junctions. EMBO J (1984) 1.86
Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice. Curr Biol (1998) 1.85
Visual transmission deficits in mice with targeted disruption of the gap junction gene connexin36. J Neurosci (2001) 1.78
Intraspecies transfer via total cellular DNA of the gene for hypoxanthine phosphoribosyltransferase into cultured mouse cells. Mol Gen Genet (1979) 1.77
Heterotypic gap junction channels (connexin26-connexin32) violate the paradigm of unitary conductance. Pflugers Arch (1995) 1.76
Functional expression of the murine connexin 36 gene coding for a neuron-specific gap junctional protein. J Membr Biol (2000) 1.74
Fatty acid-requiring mutant of bacillus subtilis defective in branched chain alpha-keto acid dehydrogenase. J Biol Chem (1971) 1.73
Impaired conduction of vasodilation along arterioles in connexin40-deficient mice. Circ Res (2000) 1.71
Immunochemical and electrophysiological characterization of murine connexin40 and -43 in mouse tissues and transfected human cells. Eur J Cell Biol (1994) 1.69
Defective propagation of signals generated by sympathetic nerve stimulation in the liver of connexin32-deficient mice. Proc Natl Acad Sci U S A (1996) 1.68
Formation of heterotypic gap junction channels by connexins 40 and 43. Circ Res (2000) 1.64
Expression of neuronal connexin36 in AII amacrine cells of the mammalian retina. J Neurosci (2001) 1.63
Electrical properties of gap junction hemichannels identified in transfected HeLa cells. Pflugers Arch (2000) 1.62
Conductances and selective permeability of connexin43 gap junction channels examined in neonatal rat heart cells. Circ Res (1997) 1.59
Conduction disturbances and increased atrial vulnerability in Connexin40-deficient mice analyzed by transesophageal stimulation. Circulation (1999) 1.57
Defective vascular development in connexin 45-deficient mice. Development (2000) 1.57
Connexin32-null mice develop demyelinating peripheral neuropathy. Glia (1998) 1.55
A quantitative analysis of connexin-specific permeability differences of gap junctions expressed in HeLa transfectants and Xenopus oocytes. J Cell Sci (1998) 1.53
Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins. Proc Natl Acad Sci U S A (1996) 1.51
Transplacental uptake of glucose is decreased in embryonic lethal connexin26-deficient mice. J Cell Biol (1998) 1.49
Assignment of the gene for galactokinase to human chromosome 17 and its regional localisation to band q21-22. Nature (1974) 1.49
Molecular cloning and functional expression of mouse connexin40, a second gap junction gene preferentially expressed in lung. J Cell Biol (1992) 1.49
Negative growth control of HeLa cells by connexin genes: connexin species specificity. Cancer Res (1995) 1.43
The murine gap junction gene connexin36 is highly expressed in mouse retina and regulated during brain development. FEBS Lett (1998) 1.43
Multiple conductance states of newly formed single gap junction channels between insect cells. Pflugers Arch (1993) 1.41
Induction of citrate transport in Bacillus subtilis during the absence of phospholipid synthesis. J Bacteriol (1971) 1.40
Is digitalis inotropy associated with enhanced slow inward calcium current? Nature (1978) 1.40
Inducible transport of citrate in a Gram-positive bacterium, Bacillus subtilis. J Biol Chem (1971) 1.39
The permeability to tetraethylammonium ions of the surface membrane and the intercalated disks of sheep and calf myocardium. J Physiol (1974) 1.39
Cellular and subcellular mechanisms of cardiac pacemaker oscillations. J Exp Biol (1979) 1.37
Endothelium-specific replacement of the connexin43 coding region by a lacZ reporter gene. Genesis (2001) 1.36
Expression pattern of connexin gene products at the early developmental stages of the mouse cardiovascular system. Circ Res (1997) 1.35
Gap junction protein connexin40 is preferentially expressed in vascular endothelium and conductive bundles of rat myocardium and is increased under hypertensive conditions. Circ Res (1993) 1.35
Cyclic adenosine monophosphate stimulates biosynthesis and phosphorylation of the 26 kDa gap junction protein in cultured mouse hepatocytes. Eur J Cell Biol (1987) 1.35
Microglia at brain stab wounds express connexin 43 and in vitro form functional gap junctions after treatment with interferon-gamma and tumor necrosis factor-alpha. Proc Natl Acad Sci U S A (2001) 1.34
Selective permeability of different connexin channels to the second messenger inositol 1,4,5-trisphosphate. J Cell Sci (2000) 1.34
High incidence of spontaneous and chemically induced liver tumors in mice deficient for connexin32. Curr Biol (1997) 1.33
Electrical properties of the nexal membrane studied in rat ventricular cell pairs. J Physiol (1986) 1.33
The actions of ouabain on intercellular coupling and conduction velocity in mammalian ventricular muscle. J Physiol (1977) 1.33
Molecular cloning and functional expression of mouse connexin-30,a gap junction gene highly expressed in adult brain and skin. J Biol Chem (1996) 1.29
Ungulate cardiac purkinje fibres: the influence of intracellular pH on the electrical cell-to-cell coupling. J Physiol (1982) 1.29
Competent Bacillus subtilis cultures synthesize a denatured DNA binding activity. Proc Natl Acad Sci U S A (1975) 1.29
Late onset and increasing expression of the gap junction protein connexin30 in adult murine brain and long-term cultured astrocytes. Glia (1999) 1.26
Inotropic effect of cyclic AMP in calf ventricular muscle studied by a cut end method. J Physiol (1976) 1.25
Functional role of connexin43 gap junction channels in adult mouse heart assessed by inducible gene deletion. J Mol Cell Cardiol (2004) 1.24
Structural abnormalities and deficient maintenance of peripheral nerve myelin in mice lacking the gap junction protein connexin 32. J Neurosci (1997) 1.22
Expression of Cx26, Cx32 and Cx43 gap junction proteins in normal and neoplastic human tissues. Int J Cancer (1992) 1.22
Immunological properties of gap junction protein from mouse liver. J Cell Biochem (1982) 1.21
Cardiac conduction abnormalities in mice lacking the gap junction protein connexin40. J Cardiovasc Electrophysiol (1999) 1.21
Biophysical properties of mouse connexin30 gap junction channels studied in transfected human HeLa cells. J Physiol (1999) 1.20
Characterization of gap junction genes expressed in F9 embryonic carcinoma cells: molecular cloning of mouse connexin31 and -45 cDNAs. Eur J Cell Biol (1992) 1.20
Cell pairs isolated from adult guinea pig and rat hearts: effects of [Ca2+]i on nexal membrane resistance. Pflugers Arch (1987) 1.20
Electrical coupling between cells of the insect Aedes albopictus. J Physiol (1992) 1.20
Differential expression of gap junction connexins in endocrine and exocrine glands. Endocrinology (1993) 1.17
Developmental regulation of connexin 40 gene expression in mouse heart correlates with the differentiation of the conduction system. Dev Dyn (1995) 1.17
Mathematical model of vertebrate gap junctions derived from electrical measurements on homotypic and heterotypic channels. J Physiol (1998) 1.16
Immunochemical characterization of the gap junction protein connexin45 in mouse kidney and transfected human HeLa cells. J Membr Biol (1994) 1.14
Functional expression of the new gap junction gene connexin47 transcribed in mouse brain and spinal cord neurons. J Neurosci (2001) 1.13
Impaired conduction in the bundle branches of mouse hearts lacking the gap junction protein connexin40. Circulation (2001) 1.13
Influence of dynamic gap junction resistance on impulse propagation in ventricular myocardium: a computer simulation study. Biophys J (2001) 1.12
Expression patterns of connexin genes in mouse retina. J Comp Neurol (2000) 1.12
Degradation and resynthesis of gap junction protein in plasma membranes of regenerating liver after partial hepatectomy or cholestasis. Proc Natl Acad Sci U S A (1983) 1.12
Electrical properties of gap junction channels in guinea-pig ventricular cell pairs revealed by exposure to heptanol. Pflugers Arch (1989) 1.12
Cytoplasmic bridges and gap junctions in an insect cell line (Aedes albopictus). Exp Physiol (1992) 1.11
Inhibition of de novo fatty acid synthesis by the antibiotic cerulenin in Bacillus subtilis: effects on citrate-Mg2+ transport and synthesis of macromolecules. Antimicrob Agents Chemother (1975) 1.11
Intracellular domains of mouse connexin26 and -30 affect diffusional and electrical properties of gap junction channels. J Membr Biol (2001) 1.10
Human mitochondrial thymidine kinase is coded for by a gene on chromosome 16 of the nucleus. Somatic Cell Genet (1977) 1.10
Stimulus complexity dependent memory impairment and changes in motor performance after deletion of the neuronal gap junction protein connexin36 in mice. Behav Brain Res (2005) 1.09
Spatiotemporal transcription of connexin45 during brain development results in neuronal expression in adult mice. Neuroscience (2003) 1.08
Connexin43 gap junctions exhibit asymmetrical gating properties. Pflugers Arch (1996) 1.07
Voltage gating of Cx43 gap junction channels involves fast and slow current transitions. Pflugers Arch (2000) 1.07
Maize mesocotyl plasmodesmata proteins cross-react with connexin gap junction protein antibodies. Plant Cell (1991) 1.07
Two gap junction genes, connexin 31.1 and 30.3, are closely linked on mouse chromosome 4 and preferentially expressed in skin. J Biol Chem (1992) 1.06
The hepatocyte-specific phenotype of murine liver cells correlates with high expression of connexin32 and connexin26 but very low expression of connexin43. Exp Cell Res (1992) 1.04
Molecular cloning and functional expression of the mouse gap junction gene connexin-57 in human HeLa cells. J Biol Chem (1999) 1.04
Simultaneous light and electron microscopic observation of immunolabeled liver 27 KD gap junction protein on ultra-thin cryosections. J Histochem Cytochem (1987) 1.03
Effects of general anesthetics on current flow across membranes in guinea pig myocytes. Am J Physiol (1989) 1.03