Published in Circ Res on May 05, 2005
Connexin channel permeability to cytoplasmic molecules. Prog Biophys Mol Biol (2007) 2.73
The conditional connexin43G138R mouse mutant represents a new model of hereditary oculodentodigital dysplasia in humans. Hum Mol Genet (2007) 1.61
Gating properties of heterotypic gap junction channels formed of connexins 40, 43, and 45. Biophys J (2006) 1.40
Properties of mouse connexin 30.2 and human connexin 31.9 hemichannels: implications for atrioventricular conduction in the heart. Proc Natl Acad Sci U S A (2006) 1.32
Connexin30.2 containing gap junction channels decelerate impulse propagation through the atrioventricular node. Proc Natl Acad Sci U S A (2006) 1.17
Permeability of homotypic and heterotypic gap junction channels formed of cardiac connexins mCx30.2, Cx40, Cx43, and Cx45. Am J Physiol Heart Circ Physiol (2007) 1.17
A stochastic four-state model of contingent gating of gap junction channels containing two "fast" gates sensitive to transjunctional voltage. Biophys J (2009) 1.14
Connexin-mediated cardiac impulse propagation: connexin 30.2 slows atrioventricular conduction in mouse heart. Trends Cardiovasc Med (2006) 1.10
Electrotonic loading of anisotropic cardiac monolayers by unexcitable cells depends on connexin type and expression level. Am J Physiol Cell Physiol (2009) 1.09
Gene regulatory networks in cardiac conduction system development. Circ Res (2012) 1.09
Gating, permselectivity and pH-dependent modulation of channels formed by connexin57, a major connexin of horizontal cells in the mouse retina. J Physiol (2009) 1.08
Connexin40 and connexin43 determine gating properties of atrial gap junction channels. J Mol Cell Cardiol (2009) 1.05
Localized expression of an Ins(1,4,5)P3 receptor at the myoendothelial junction selectively regulates heterocellular Ca2+ communication. J Cell Sci (2008) 1.04
Heterotypic gap junction channels as voltage-sensitive valves for intercellular signaling. Proc Natl Acad Sci U S A (2009) 1.02
Cx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delay. Development (2009) 1.01
Cx29 and Cx32, two connexins expressed by myelinating glia, do not interact and are functionally distinct. J Neurosci Res (2008) 1.01
Cx30.2 can form heteromeric gap junction channels with other cardiac connexins. Biochem Biophys Res Commun (2008) 0.92
Electrical synapses and the development of inhibitory circuits in the thalamus. J Physiol (2016) 0.92
Programming and isolation of highly pure physiologically and pharmacologically functional sinus-nodal bodies from pluripotent stem cells. Stem Cell Reports (2014) 0.91
Determinants of heterogeneity, excitation and conduction in the sinoatrial node: a model study. PLoS Comput Biol (2010) 0.90
Modulation of metabolic communication through gap junction channels by transjunctional voltage; synergistic and antagonistic effects of gating and ionophoresis. Biochim Biophys Acta (2011) 0.89
Characterization of sinoatrial node in four conduction system marker mice. J Mol Cell Cardiol (2007) 0.88
Multilayered regulation of cardiac ion channels. Biochim Biophys Acta (2012) 0.87
Sex-dependent gene regulatory networks of the heart rhythm. Funct Integr Genomics (2009) 0.86
Mechanism of inhibition of connexin channels by the quinine derivative N-benzylquininium. J Gen Physiol (2012) 0.85
Differentiation induction of mouse embryonic stem cells into sinus node-like cells by suramin. Int J Cardiol (2009) 0.85
Connexin diversity in the heart: insights from transgenic mouse models. Front Pharmacol (2013) 0.84
Channeling diversity: gap junction expression in the heart. Heart Rhythm (2011) 0.83
Decreased intercellular coupling improves the function of cardiac pacemakers derived from mouse embryonic stem cells. J Mol Cell Cardiol (2008) 0.83
Neurons and β-cells of the pancreas express connexin36, forming gap junction channels that exhibit strong cationic selectivity. J Membr Biol (2012) 0.83
Aspartic acid residue D3 critically determines Cx50 gap junction channel transjunctional voltage-dependent gating and unitary conductance. Biophys J (2012) 0.83
Influence of v5/6-His tag on the properties of gap junction channels composed of connexin43, connexin40 or connexin45. J Membr Biol (2011) 0.81
Mechanisms underlying the cardiac pacemaker: the role of SK4 calcium-activated potassium channels. Acta Pharmacol Sin (2016) 0.80
Heterotypic connexin50/connexin50 mutant gap junction channels reveal interactions between two hemichannels during transjunctional voltage-dependent gating. J Physiol (2012) 0.78
Cell junctions in the specialized conduction system of the heart. Cell Commun Adhes (2014) 0.77
Angiotensin II promotes differentiation of mouse c-kit-positive cardiac stem cells into pacemaker-like cells. Mol Med Rep (2015) 0.77
Fibroblasts: modulating the rhythm of the heart. J Physiol (2008) 0.77
Electrical and mechanical stimulation of cardiac cells and tissue constructs. Adv Drug Deliv Rev (2015) 0.76
Cardiac Cx43, Cx40 and Cx45 co-assembling: involvement of connexins epitopes in formation of hemichannels and Gap junction channels. BMC Cell Biol (2017) 0.75
Connexin mutant embryonic stem cells and human diseases. World J Stem Cells (2014) 0.75
Connexin30.2: In Vitro Interaction with Connexin36 in HeLa Cells and Expression in AII Amacrine Cells and Intrinsically Photosensitive Ganglion Cells in the Mouse Retina. Front Mol Neurosci (2016) 0.75
MyoR modulates cardiac conduction by repressing Gata4. Mol Cell Biol (2014) 0.75
Murine Electrophysiological Models of Cardiac Arrhythmogenesis. Physiol Rev (2017) 0.75
Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications. Pharmacol Rev (2017) 0.75
RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucleic Acids Res (1987) 14.53
Cardiac malformation in neonatal mice lacking connexin43. Science (1995) 5.51
Structural and functional diversity of connexin genes in the mouse and human genome. Biol Chem (2002) 5.40
Gap junctions and the connexin protein family. Cardiovasc Res (2004) 3.66
Electrophysiological features of the mouse sinoatrial node in relation to connexin distribution. Cardiovasc Res (2001) 2.64
Biophysical properties of gap junction channels formed by mouse connexin40 in induced pairs of transfected human HeLa cells. Biophys J (1995) 2.41
Abnormal cardiac conduction and morphogenesis in connexin40 and connexin43 double-deficient mice. Circ Res (2000) 2.37
Gap junction channel gating. Biochim Biophys Acta (2004) 2.34
Gating properties of gap junction channels assembled from connexin43 and connexin43 fused with green fluorescent protein. Biophys J (2001) 2.15
Unique and shared functions of different connexins in mice. Curr Biol (2000) 2.10
Functional properties of channels formed by the neuronal gap junction protein connexin36. J Neurosci (1999) 1.90
Functional expression of the murine connexin 36 gene coding for a neuron-specific gap junctional protein. J Membr Biol (2000) 1.74
Coupling asymmetry of heterotypic connexin 45/ connexin 43-EGFP gap junctions: properties of fast and slow gating mechanisms. Proc Natl Acad Sci U S A (2002) 1.71
Formation of heterotypic gap junction channels by connexins 40 and 43. Circ Res (2000) 1.64
Replacement of connexin40 by connexin45 in the mouse: impact on cardiac electrical conduction. Circ Res (2003) 1.58
Defective vascular development in connexin 45-deficient mice. Development (2000) 1.57
Connexins in mammalian heart function. Bioessays (1996) 1.45
Connexin45 expression is preferentially associated with the ventricular conduction system in mouse and rat heart. Circ Res (1998) 1.34
Molecular cloning, functional expression, and tissue distribution of a novel human gap junction-forming protein, connexin-31.9. Interaction with zona occludens protein-1. J Biol Chem (2002) 1.33
Role of gap junctions in cardiac conduction and development: insights from the connexin knockout mice. Circ Res (2000) 1.20
Remodelling of gap junctions and connexin expression in heart disease. Biochim Biophys Acta (2004) 1.15
Impaired conduction in the bundle branches of mouse hearts lacking the gap junction protein connexin40. Circulation (2001) 1.13
Virtual cloning, functional expression, and gating analysis of human connexin31.9. Am J Physiol Cell Physiol (2002) 1.10
Heart and head defects in mice lacking pairs of connexins. Dev Biol (2004) 0.97
Differences in expression patterns between mouse connexin-30.2 (Cx30.2) and its putative human orthologue, connexin-31.9. FEBS Lett (2003) 0.87
Swapping connexin genes: how big is the gap? Circ Res (2004) 0.80
Structural and functional diversity of connexin genes in the mouse and human genome. Biol Chem (2002) 5.40
A novel signaling pathway impact analysis. Bioinformatics (2008) 5.06
Gap junctions and the connexin protein family. Cardiovasc Res (2004) 3.66
Astroglial metabolic networks sustain hippocampal synaptic transmission. Science (2008) 3.49
Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia. Nature (2007) 3.46
Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture. Proc Natl Acad Sci U S A (2001) 3.17
Expression and functions of neuronal gap junctions. Nat Rev Neurosci (2005) 2.91
The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus. J Neurosci (2006) 2.85
Gating and regulation of connexin 43 (Cx43) hemichannels. Proc Natl Acad Sci U S A (2003) 2.79
Targeted ablation of connexin26 in the inner ear epithelial gap junction network causes hearing impairment and cell death. Curr Biol (2002) 2.72
Impaired permeability to Ins(1,4,5)P3 in a mutant connexin underlies recessive hereditary deafness. Nat Cell Biol (2004) 2.70
An innexin-dependent cell network establishes left-right neuronal asymmetry in C. elegans. Cell (2007) 2.41
Gap junction channel gating. Biochim Biophys Acta (2004) 2.34
Clinical benefit of statin pretreatment in patients undergoing percutaneous coronary intervention: a collaborative patient-level meta-analysis of 13 randomized studies. Circulation (2011) 2.34
The clopidogrel resistance can be attenuated with triple antiplatelet therapy in patients undergoing drug-eluting stents implantation. Int J Cardiol (2008) 2.31
A new strategy for discontinuation of dual antiplatelet therapy: the RESET Trial (REal Safety and Efficacy of 3-month dual antiplatelet Therapy following Endeavor zotarolimus-eluting stent implantation). J Am Coll Cardiol (2012) 2.28
New roles for astrocytes: gap junction hemichannels have something to communicate. Trends Neurosci (2003) 2.25
Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release. Diabetes (2005) 2.24
Slow conduction and enhanced anisotropy increase the propensity for ventricular tachyarrhythmias in adult mice with induced deletion of connexin43. Circulation (2004) 2.23
Connexin30 (Gjb6)-deficiency causes severe hearing impairment and lack of endocochlear potential. Hum Mol Genet (2003) 2.17
Connexin-based gap junction hemichannels: gating mechanisms. Biochim Biophys Acta (2005) 2.16
Low peak bone mass and attenuated anabolic response to parathyroid hormone in mice with an osteoblast-specific deletion of connexin43. J Cell Sci (2006) 2.06
Connexin hemichannel-mediated CO2-dependent release of ATP in the medulla oblongata contributes to central respiratory chemosensitivity. J Physiol (2010) 1.81
Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation. Am J Pathol (2003) 1.79
An update on connexin genes and their nomenclature in mouse and man. Cell Commun Adhes (2003) 1.77
Differentiation of extrahepatic bile duct cholangiocarcinoma from benign stricture: findings at MRCP versus ERCP. Radiology (2004) 1.74
Coupling asymmetry of heterotypic connexin 45/ connexin 43-EGFP gap junctions: properties of fast and slow gating mechanisms. Proc Natl Acad Sci U S A (2002) 1.71
Cardiomyocyte-restricted deletion of connexin43 during mouse development. J Mol Cell Cardiol (2006) 1.70
Role of olivary electrical coupling in cerebellar motor learning. Neuron (2008) 1.67
Effectiveness and safety of endovascular aneurysm treatment in patients with vasculo-Behçet disease. J Endovasc Ther (2009) 1.66
Incidences, predictors, and clinical outcomes of acute and late stent malapposition detected by optical coherence tomography after drug-eluting stent implantation. Circ Cardiovasc Interv (2014) 1.62
Correlative studies of gating in Cx46 and Cx50 hemichannels and gap junction channels. Biophys J (2004) 1.62
Connexin 43 enhances the adhesivity and mediates the invasion of malignant glioma cells. J Neurosci (2002) 1.62
The conditional connexin43G138R mouse mutant represents a new model of hereditary oculodentodigital dysplasia in humans. Hum Mol Genet (2007) 1.61
Accelerated hippocampal spreading depression and enhanced locomotory activity in mice with astrocyte-directed inactivation of connexin43. J Neurosci (2003) 1.59
Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas. J Biol Chem (2009) 1.58
A central role of connexin 43 in hypoxic preconditioning. J Neurosci (2008) 1.56
Gastric cancer staging at multi-detector row CT gastrography: comparison of transverse and volumetric CT scanning. Radiology (2005) 1.56
Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue. Brain Res Brain Res Rev (2004) 1.54
Connexin43 interacts with NOV: a possible mechanism for negative regulation of cell growth in choriocarcinoma cells. J Biol Chem (2004) 1.50
Connexin 47 (Cx47)-deficient mice with enhanced green fluorescent protein reporter gene reveal predominant oligodendrocytic expression of Cx47 and display vacuolized myelin in the CNS. J Neurosci (2003) 1.48
Randomised comparison of strut coverage between Nobori biolimus-eluting and sirolimus-eluting stents: an optical coherence tomography analysis. EuroIntervention (2014) 1.47
C-terminal truncation of connexin43 changes number, size, and localization of cardiac gap junction plaques. Circ Res (2007) 1.46
The connexin 40 A96S mutation causes renin-dependent hypertension. J Am Soc Nephrol (2011) 1.46
Connexin 30 is expressed in the mouse sino-atrial node and modulates heart rate. Cardiovasc Res (2010) 1.45
Differentially altered Ca2+ regulation and Ca2+ permeability in Cx26 hemichannels formed by the A40V and G45E mutations that cause keratitis ichthyosis deafness syndrome. J Gen Physiol (2010) 1.45
Cardiac morphogenetic defects and conduction abnormalities in mice homozygously deficient for connexin40 and heterozygously deficient for connexin45. J Mol Cell Cardiol (2006) 1.45
Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafness. Proc Natl Acad Sci U S A (2007) 1.44
Anatomic and functional evaluation of bifurcation lesions undergoing percutaneous coronary intervention. Circ Cardiovasc Interv (2010) 1.42
Extracellular Ca²⁺ acts as a mediator of communication from neurons to glia. Sci Signal (2012) 1.42
Deformation of network connectivity in the inferior olive of connexin 36-deficient mice is compensated by morphological and electrophysiological changes at the single neuron level. J Neurosci (2003) 1.41
Conductance and permeability of the residual state of connexin43 gap junction channels. J Gen Physiol (2002) 1.41
[Prophylactic effect of Lactobacillus GG in animal colitis and its effect on cytokine secretion and mucin gene expressions]. Korean J Gastroenterol (2004) 1.41
Optical coherence tomography-based predictors for creatine kinase-myocardial band elevation after elective percutaneous coronary intervention for in-stent restenosis. Catheter Cardiovasc Interv (2014) 1.41
Gating properties of heterotypic gap junction channels formed of connexins 40, 43, and 45. Biophys J (2006) 1.40
Connexin mediates gap junction-independent resistance to cellular injury. J Neurosci (2003) 1.38
Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia. Lab Invest (2004) 1.38
Functional expression of connexin57 in horizontal cells of the mouse retina. Eur J Neurosci (2004) 1.38
Connexin 30 deficiency impairs renal tubular ATP release and pressure natriuresis. J Am Soc Nephrol (2009) 1.37
The transcriptome of the fetal inflammatory response syndrome. Am J Reprod Immunol (2010) 1.37
Deletion of connexin45 in mouse retinal neurons disrupts the rod/cone signaling pathway between AII amacrine and ON cone bipolar cells and leads to impaired visual transmission. J Neurosci (2005) 1.34
Identification of specific ligands for orphan olfactory receptors. G protein-dependent agonism and antagonism of odorants. J Biol Chem (2004) 1.34
Protein kinase A-mediated phosphorylation of connexin36 in mouse retina results in decreased gap junctional communication between AII amacrine cells. J Biol Chem (2006) 1.33
Properties of mouse connexin 30.2 and human connexin 31.9 hemichannels: implications for atrioventricular conduction in the heart. Proc Natl Acad Sci U S A (2006) 1.32
Determinants of gating polarity of a connexin 32 hemichannel. Biophys J (2004) 1.32
Defective epidermal barrier in neonatal mice lacking the C-terminal region of connexin43. Mol Biol Cell (2004) 1.31
Emerging complexities in identity and function of glial connexins. Trends Neurosci (2005) 1.31
Reduction of high-frequency network oscillations (ripples) and pathological network discharges in hippocampal slices from connexin 36-deficient mice. J Physiol (2002) 1.30
FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels. Proc Natl Acad Sci U S A (2010) 1.30
Invasive colorectal micropapillary carcinoma: an aggressive variant of adenocarcinoma. Hum Pathol (2006) 1.30
Connexin-43 upregulation in micrometastases and tumor vasculature and its role in tumor cell attachment to pulmonary endothelium. BMC Med (2008) 1.29
The frequency, clinical significance, and pathological features of chronic chorioamnionitis: a lesion associated with spontaneous preterm birth. Mod Pathol (2010) 1.29
Increased apoptosis and inflammation after focal brain ischemia in mice lacking connexin43 in astrocytes. Am J Pathol (2004) 1.28
The neuronal connexin36 interacts with and is phosphorylated by CaMKII in a way similar to CaMKII interaction with glutamate receptors. Proc Natl Acad Sci U S A (2008) 1.28
Paracrine signaling through plasma membrane hemichannels. Biochim Biophys Acta (2012) 1.28
Connexin-caused genetic diseases and corresponding mouse models. Antioxid Redox Signal (2009) 1.27
Connexin36 mediates gap junctional coupling of alpha-ganglion cells in mouse retina. J Comp Neurol (2005) 1.26
Loss of ceramide synthase 3 causes lethal skin barrier disruption. Hum Mol Genet (2011) 1.26