Published in Nucleic Acids Res on September 11, 1995
Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs. Nucleic Acids Res (2000) 1.26
Determination of affinity, stoichiometry and sequence selectivity of minor groove binder complexes with double-stranded oligodeoxynucleotides by electrospray ionization mass spectrometry. Nucleic Acids Res (2002) 1.14
A host-guest approach for determining drug-DNA interactions: an example using netropsin. Nucleic Acids Res (2005) 1.04
Design of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif. J Am Chem Soc (2007) 1.02
Sequence and length dependent thermodynamic differences in heterocyclic diamidine interactions at AT base pairs in the DNA minor groove. Biophys Chem (2007) 0.97
DNA minor groove induced dimerization of heterocyclic cations: compound structure, binding affinity, and specificity for a TTAA site. J Mol Biol (2010) 0.96
Induced topological changes in DNA complexes: influence of DNA sequences and small molecule structures. Nucleic Acids Res (2011) 0.95
Vaccinia virus intermediate and late promoter elements are targeted by the TATA-binding protein. J Virol (2006) 0.92
Sequence-dependent variation in DNA minor groove width dictates orientational preference of Hoechst 33258 in A-tract recognition: solution NMR structure of the 2:1 complex with d(CTTTTGCAAAAG)(2). Nucleic Acids Res (2000) 0.91
Pharmacology of novel heteroaromatic polycycle antibacterials. Antimicrob Agents Chemother (2003) 0.89
Crystal structure of a trypanocidal 4,4'-bis(imidazolinylamino)diphenylamine bound to DNA. Biochemistry (2009) 0.89
DNA minor groove recognition of a non-self-complementary AT-rich sequence by a tris-benzimidazole ligand. Nucleic Acids Res (1999) 0.89
DNA and the chromosome - varied targets for chemotherapy. Cell Chromosome (2004) 0.88
Resolution of mixed site DNA complexes with dimer-forming minor-groove binders by using electrospray ionization mass spectrometry: compound structure and DNA sequence effects. Chemistry (2015) 0.87
Use of capillary electrophoresis in the study of ligand-DNA interactions. Nucleic Acids Res (1998) 0.87
Interaction of minor groove binding ligands with long AT tracts. Nucleic Acids Res (1997) 0.87
Ensemble and single-molecule fluorescence spectroscopic study of the binding modes of the bis-benzimidazole derivative Hoechst 33258 with DNA. Nucleic Acids Res (2003) 0.86
Antiviral activity of distamycin A against vaccinia virus is the result of inhibition of postreplicative mRNA synthesis. J Virol (2004) 0.86
Structure of a bis-amidinium derivative of hoechst 33258 complexed to dodecanucleotide d(CGCGAATTCGCG)2: the role of hydrogen bonding in minor groove drug-DNA recognition. Nucleic Acids Res (1997) 0.85
Specific down-regulation of an engineered human cyclin D1 promoter by a novel DNA-binding ligand in intact cells. Nucleic Acids Res (2001) 0.84
Sequence dependencies of DNA deformability and hydration in the minor groove. Biophys J (2009) 0.84
Unusually strong binding to the DNA minor groove by a highly twisted benzimidazole diphenylether: induced fit and bound water. Biochemistry (2007) 0.84
Molecular basis for sequence-dependent induced DNA bending. Chembiochem (2013) 0.83
The AT-Hook motif as a versatile minor groove anchor for promoting DNA binding of transcription factor fragments. Chem Sci (2015) 0.82
A novel approach using electrospray ionization mass spectrometry to study competitive binding of small molecules with mixed DNA sequences. Anal Bioanal Chem (2014) 0.80
Role of minor groove width and hydration pattern on amsacrine interaction with DNA. PLoS One (2013) 0.79
Detection of a single base exchange in PCR-amplified DNA fragments using agarose gel electrophoresis containing bisbenzimide-PEG. Nucleic Acids Res (1997) 0.79
Sliding Box Docking: a new stand-alone tool for managing docking-based virtual screening along the DNA helix axis. Bioinformation (2013) 0.79
Effect of DNA groove binder distamycin A upon chromatin structure. PLoS One (2011) 0.78
May the Best Molecule Win: Competition ESI Mass Spectrometry. Int J Mol Sci (2015) 0.77
Microarray analysis of the in vivo sequence preferences of a minor groove binding drug. BMC Genomics (2008) 0.75
DNA microstructure influences selective binding of small molecules designed to target mixed-site DNA sequences. Nucleic Acids Res (2017) 0.75
Conformational changes of the phenyl and naphthyl isocyanate-DNA adducts during DNA replication and by minor groove binding molecules. Nucleic Acids Res (2013) 0.75
Structure of a B-DNA dodecamer. II. Influence of base sequence on helix structure. J Mol Biol (1981) 7.18
The molecular origin of DNA-drug specificity in netropsin and distamycin. Proc Natl Acad Sci U S A (1985) 5.14
Map of distamycin, netropsin, and actinomycin binding sites on heterogeneous DNA: DNA cleavage-inhibition patterns with methidiumpropyl-EDTA.Fe(II). Proc Natl Acad Sci U S A (1982) 3.81
DNA structural variations produced by actinomycin and distamycin as revealed by DNAase I footprinting. Nucleic Acids Res (1984) 2.69
Binding of Hoechst 33258 to the minor groove of B-DNA. J Mol Biol (1987) 2.46
Binding of an antitumor drug to DNA, Netropsin and C-G-C-G-A-A-T-T-BrC-G-C-G. J Mol Biol (1985) 2.43
Enthalpy-entropy compensations in drug-DNA binding studies. Proc Natl Acad Sci U S A (1987) 2.16
The molecular structure of the complex of Hoechst 33258 and the DNA dodecamer d(CGCGAATTCGCG). Nucleic Acids Res (1988) 2.07
Structure of an alternating-B DNA helix and its relationship to A-tract DNA. Proc Natl Acad Sci U S A (1988) 2.04
Origins of netropsin binding affinity and specificity: correlations of thermodynamic and structural data. Proc Natl Acad Sci U S A (1987) 1.83
Molecular recognition of B-DNA by Hoechst 33258. Nucleic Acids Res (1985) 1.80
Molecular structure of the netropsin-d(CGCGATATCGCG) complex: DNA conformation in an alternating AT segment. Biochemistry (1989) 1.80
Assignment of DNA binding sites for 4',6-diamidine-2-phenylindole and bisbenzimide (Hoechst 33258). A comparative footprinting study. Biochim Biophys Acta (1988) 1.60
Binding of a Hoechst dye to d(CGCGATATCGCG) and its influence on the conformation of the DNA fragment. Biochemistry (1989) 1.51
Influence of nucleotide sequence on dA.dT-specific binding of Netropsin to double stranded DNA. Nucleic Acids Res (1979) 1.47
Structure of a B-DNA decamer with a central T-A step: C-G-A-T-T-A-A-T-C-G. J Mol Biol (1992) 1.36
Crystal structure of a berenil-dodecanucleotide complex: the role of water in sequence-specific ligand binding. EMBO J (1990) 1.26
Crystal structure of a berenil-d(CGCAAATTTGCG) complex. An example of drug-DNA recognition based on sequence-dependent structural features. J Mol Biol (1992) 1.22
Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258. Eur J Biochem (1994) 1.20
Sequence-dependent effects in drug-DNA interaction: the crystal structure of Hoechst 33258 bound to the d(CGCAAATTTGCG)2 duplex. Nucleic Acids Res (1994) 1.20
Comparison of binding sites in DNA for berenil, netropsin and distamycin. A footprinting study. Eur J Biochem (1987) 1.19
Determination of netropsin-DNA binding constants from footprinting data. Biochemistry (1988) 1.15
Interaction of Hoechst 33258 with the minor groove of the A + T-rich DNA duplex d(GGTAATTACC)2 studied in solution by NMR spectroscopy. Eur J Biochem (1993) 1.12
Hydration of DNA in aqueous solution: NMR evidence for a kinetic destabilization of the minor groove hydration of d-(TTAA)2 versus d-(AATT)2 segments. Nucleic Acids Res (1994) 1.06
Hydroxyl radical footprinting of the sequence-selective binding of netropsin and distamycin to DNA. FEBS Lett (1987) 1.02
Detection of drug binding to DNA by hydroxyl radical footprinting. Relationship of distamycin binding sites to DNA structure and positioned nucleosomes on 5S RNA genes of Xenopus. Biochemistry (1990) 0.99
Probing the conformations of eight cloned DNA dodecamers; CGCGAATTCGCG, CGCGTTAACGCG, CGCGTATACGCG, CGCGATATCGCG, CGCAAATTTGCG, CGCTTTAAAGCG, CGCGGATCCGCG and CGCGGTACCGCG. Nucleic Acids Res (1992) 0.98
Crystal and molecular structure of d(CGTAGATCTACG) at 2.25 A resolution. J Mol Biol (1993) 0.98
Interaction of berenil with the tyrT DNA sequence studied by footprinting and molecular modelling. Implications for the design of sequence-specific DNA recognition agents. Nucleic Acids Res (1990) 0.89
The crystal structure of the DNA-binding drug berenil: molecular modelling studies of berenil-DNA complexes. Nucleic Acids Res (1987) 0.87
Solution structure of [d(GCGTATACGC)]2. J Mol Biol (1992) 0.86
H-NMR studies on d(GCTTAAGC)2 and its complex with berenil. Eur J Biochem (1992) 0.81
A massive outbreak in Milwaukee of cryptosporidium infection transmitted through the public water supply. N Engl J Med (1994) 15.92
Pupillary signs in diabetic autonomic neuropathy. Br Med J (1978) 2.79
Effect of exercise referral schemes in primary care on physical activity and improving health outcomes: systematic review and meta-analysis. BMJ (2011) 2.74
DNA structural variations produced by actinomycin and distamycin as revealed by DNAase I footprinting. Nucleic Acids Res (1984) 2.69
The Brighton resuscitation ambulances: a continuing experiment in prehospital care by ambulance staff. Br Med J (1976) 2.66
Crossvalidation of anthropometry against magnetic resonance imaging for the assessment of visceral and subcutaneous adipose tissue in children. Int J Obes (Lond) (2006) 2.21
The impact of a multidisciplinary breast cancer center on recommendations for patient management: the University of Pennsylvania experience. Cancer (2001) 1.99
Depression of chloride transport by carbonic anhydrase inhibitors in the absence of carbonic anhydrase. Nature (1967) 1.92
Identification and treatment of risk factors for coronary heart disease in general practice: a possible screening model. Br Med J (Clin Res Ed) (1988) 1.85
The clinical effectiveness and cost-effectiveness of exercise referral schemes: a systematic review and economic evaluation. Health Technol Assess (2011) 1.59
Chlorine and survival of "rugose" Vibrio cholerae. Lancet (1992) 1.43
Bilateral sudden visual loss due to sphenoid mucocele in Albright's syndrome. Br J Ophthalmol (1995) 1.40
Autologous stem-cell transplant after conventional dose adjuvant chemotherapy for high-risk breast cancer: impact on the delivery of local-regional radiation therapy. Ann Oncol (1999) 1.40
Towards mixed sequence recognition by triple helix formation. Nucleic Acids Res (1999) 1.32
Kinetics of the interaction between echinomycin and deoxyribonucleic acid. Biochemistry (1981) 1.31
Investigations into the sequence-selective binding of mithramycin and related ligands to DNA. Nucleic Acids Res (1985) 1.23
Physically active families - de-bunking the myth? A qualitative study of family participation in physical activity. Child Care Health Dev (2009) 1.23
Extension of the therapeutic window for recombinant tissue plasminogen activator with argatroban in a rat model of embolic stroke. Stroke (2001) 1.23
Acid secretion, Na+ absorption, and the origin of the potential difference across isolated mammalian stomachs. Am J Dig Dis (1969) 1.22
Physical activity patterns in normal, overweight and obese individuals using minute-by-minute accelerometry. Eur J Clin Nutr (2000) 1.21
LX4211, a dual SGLT1/SGLT2 inhibitor, improved glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial. Clin Pharmacol Ther (2012) 1.21
Site and sequence specificity of the daunomycin-DNA interaction. Biochemistry (1987) 1.20
Affinity of mismatch-binding protein MutS for heteroduplexes containing different mismatches. Biochem J (2001) 1.20
First-cycle blood counts and subsequent neutropenia, dose reduction, or delay in early-stage breast cancer therapy. J Clin Oncol (1998) 1.19
Diethyl pyrocarbonate can detect a modified DNA structure induced by the binding of quinoxaline antibiotics. Nucleic Acids Res (1988) 1.18
The use of micrococcal nuclease as a probe for drug-binding sites on DNA. Biochim Biophys Acta (1987) 1.15
Obesity, fitness and health in Taiwanese children and adolescents. Eur J Clin Nutr (2006) 1.15
Footprinting studies on ligands which stabilize DNA triplexes: effects on stringency within a parallel triple helix. Biochemistry (1995) 1.15
5-(1-propargylamino)-2'-deoxyuridine (UP): a novel thymidine analogue for generating DNA triplexes with increased stability. Nucleic Acids Res (1999) 1.12
Magnetic resonance imaging of abdominal adiposity in a large cohort of British children. Int J Obes (Lond) (2007) 1.12
Synchronous multicentric osteosarcoma: the case for metastases. Skeletal Radiol (1997) 1.11
Effect of a triplex-binding ligand on parallel and antiparallel DNA triple helices using short unmodified and acridine-linked oligonucleotides. Biochemistry (1994) 1.11
Nucleotide sequence binding preferences of nogalamycin investigated by DNase I footprinting. Biochemistry (1986) 1.10
Comparison of media for recovery of total coliform bacteria from chemically treated water. Appl Environ Microbiol (1987) 1.09
A pragmatic randomised controlled trial to evaluate the cost-effectiveness of a physical activity intervention as a treatment for depression: the treating depression with physical activity (TREAD) trial. Health Technol Assess (2012) 1.08
Preferred binding sites for [N-MeCYs(3), N-MeCys(7)]TANDEM determined using a universal footprinting substrate. Anal Biochem (2001) 1.07
Footprinting at low temperatures: evidence that ethidium and other simple intercalators can discriminate between different nucleotide sequences. Nucleic Acids Res (1987) 1.07
Kinetics of dissociation of quinoxaline antibiotics from DNA. Biochim Biophys Acta (1981) 1.05
DNase I footprinting of triple helix formation at polypurine tracts by acridine-linked oligopyrimidines: stringency, structural changes and interaction with minor groove binding ligands. Biochim Biophys Acta (1994) 1.04
Equilibrium and kinetic studies on the binding of des-N-tetramethyltriostin A to DNA. Biochim Biophys Acta (1982) 1.03
Complications in ENT--a nationwide audit carried out in November 1992. Clin Otolaryngol Allied Sci (1994) 1.03
Kinetics of dissociation of nogalamycin from DNA: comparison with other anthracycline antibiotics. Biochim Biophys Acta (1985) 1.00
Motivation for physical activity and weight management. Int J Obes Relat Metab Disord (1998) 1.00
DNA sequence recognition by under-methylated analogues of triostin A. Nucleic Acids Res (1986) 0.99
Processes associated with participation and adherence to a 12-month exercise programme for adults aged 70 and older. J Health Psychol (2010) 0.99
DNA sequence preferences for an intercalating porphyrin compound revealed by footprinting. Nucleic Acids Res (1987) 0.99
Binding of quinoline analogues of echinomycin to deoxyribonucleic acid. Role of the chromophores. Biochem J (1980) 0.99
Comparison of hormonal and metabolic effects of salbutamol infusion in normal subjects and insulin-requiring diabetics. Lancet (1980) 0.98
High-resolution footprinting studies of drug-DNA complexes using chemical and enzymatic probes. Methods Enzymol (2001) 0.98
Coats' disease. Metab Pediatr Ophthalmol (1980) 0.98
Gastroepiploic-coronary anastomosis. A viable alternative bypass graft. J Thorac Cardiovasc Surg (1987) 0.98
Feasibility of an exercise rehabilitation programme for cancer patients. Eur J Cancer Care (Engl) (2006) 0.97
Role of head group structure in the phase behavior of amino phospholipids. 1. Hydrated and dehydrated lamellar phases of saturated phosphatidylethanolamine analogues. Biochemistry (1986) 0.97
Physical activity by stealth? The potential health benefits of a workplace transport plan. Public Health (2011) 0.97
DNA sequence specificity of a naphthylquinoline triple helix-binding ligand. Nucleic Acids Res (1996) 0.97
Preventive intervention for living donor psychosocial outcomes: feasibility and efficacy in a randomized controlled trial. Am J Transplant (2013) 0.96
Interaction of mithramycin with metal ions and DNA. Biochem Biophys Res Commun (1989) 0.95
Comparison of the effects of four commercially available weight-loss programmes on lipid-based cardiovascular risk factors. Public Health Nutr (2008) 0.94
DNA sequence preferences for the anti-cancer drug mitoxanthrone and related anthraquinones revealed by DNase I footprinting. FEBS Lett (1986) 0.94
Role of head group structure in the phase behavior of amino phospholipids. 2. Lamellar and nonlamellar phases of unsaturated phosphatidylethanolamine analogues. Biochemistry (1986) 0.93
The effect of metabolic control on leucine metabolism in type 1 (insulin-dependent) diabetic patients. Diabetologia (1986) 0.93
DNA triple helix formation at oligopurine sites containing multiple contiguous pyrimidines. Nucleic Acids Res (1997) 0.93
Interaction between synthetic analogues of quinoxaline antibiotics and nucleic acids: role of the disulphide cross-bridge and D-amino acid centres in des-N-tetramethyl-triostin A. Br J Pharmacol (1980) 0.93
High resolution hydroxyl radical footprinting of the binding of mithramycin and related antibiotics to DNA. Nucleic Acids Res (1989) 0.92
The effect of HhaI methylation on DNA local structure. Biochem J (1986) 0.92
Novel fluorescent phospholipids for assays of lipid mixing between membranes. Biochemistry (1987) 0.92
The effects of actinomycin on the structure of dAn.dTn and (dA-dT)n regions surrounding its GC binding site. A footprinting study. J Biol Chem (1991) 0.92
Effects of sequence selective drugs on the gel mobility of a bent DNA fragment. Biochem Biophys Res Commun (1990) 0.92
Pneumocystis pneumonia and disseminated toxoplasmosis in a male homosexual. Br Med J (Clin Res Ed) (1983) 0.91
Alternate-strand DNA triple-helix formation using short acridine-linked oligonucleotides. Biochem J (1994) 0.91
Coronary heart disease risk assessment in diabetes mellitus: comparison of UKPDS risk engine with Framingham risk assessment function and its clinical implications. Diabet Med (2004) 0.91
Modeling the cost-effectiveness of granulocyte colony-stimulating factor use in early-stage breast cancer. J Clin Oncol (1998) 0.90
Problems of carotid Doppler scanning which can be overcome by using frequency analysis. Stroke (1982) 0.90
Evidence of different binding sites for nogalamycin in DNA revealed by association kinetics. Biochim Biophys Acta (1984) 0.90
Coralyne has a preference for intercalation between TA.T triples in intramolecular DNA triple helices. Nucleic Acids Res (1997) 0.90
Specificity of antiparallel DNA triple helix formation. Biochemistry (1996) 0.90
Exercise and health psychology: emerging relationships. Br J Med Psychol (1989) 0.89
Comparison of antiparallel A.AT and T.AT triplets within an alternate strand DNA triple helix. Nucleic Acids Res (1994) 0.89
Relative stability of triplexes containing different numbers of T.AT and C+.GC triplets. Nucleic Acids Res (1997) 0.89
Interaction of echinomycin with An.Tn. and (AT)n regions flanking its CG binding site. Nucleic Acids Res (1991) 0.89
Interaction of berenil with the tyrT DNA sequence studied by footprinting and molecular modelling. Implications for the design of sequence-specific DNA recognition agents. Nucleic Acids Res (1990) 0.89
Recognition of GC base pairs by triplex forming oligonucleotides containing nucleosides derived from 2-aminopyridine. Nucleic Acids Res (1997) 0.88
Triple helix formation at A8XA8.T8YT8. FEBS Lett (1993) 0.88
Nucleosome core particles inhibit DNA triple helix formation. Biochem J (1996) 0.88
Left ventricular thrombus in the absence of detectable heart disease. Chest (1989) 0.87
Interaction of minor groove binding ligands with long AT tracts. Nucleic Acids Res (1997) 0.87
Assessment of non-invasive electrocochleography. J Laryngol Otol (1980) 0.87
Triple-helix formation at different positions on nucleosomal DNA. Biochemistry (1998) 0.87
Kinetic evidence for redistribution of actinomycin molecules between potential DNA-binding sites. Eur J Biochem (1984) 0.87
Differential inhibition of a restriction enzyme by quinoxaline antibiotics. Biochim Biophys Acta (1982) 0.86
Detection of occlusive disease of the carotid artery with continuous wave Doppler spectral analysis. Surg Gynecol Obstet (1982) 0.86
Improving waterborne disease outbreak investigations. Int J Environ Health Res (2001) 0.86
Cost-effectiveness of MR imaging and core-needle biopsy in the preoperative work-up of suspicious breast lesions. Radiology (1999) 0.86
The GC-selective ligand mithramycin alters the structure of (AT)n sequences flanking its binding sites. FEBS Lett (1990) 0.86
Cerebrovascular assessment using a Doppler carotid scanner and real-time frequency analysis. J Clin Ultrasound (1981) 0.85
Extension of DNA triple helix formation to a neighbouring (AT)n site. FEBS Lett (1995) 0.85
Effectiveness of etoposide chemomobilization in lymphoma patients undergoing auto-SCT. Bone Marrow Transplant (2012) 0.85
Preparation and DNA-binding properties of substituted triostin antibiotics. Antimicrob Agents Chemother (1983) 0.85
The use of radiolabelled triostin antibiotics to measure low levels of binding to deoxyribonucleic acid. Biochem J (1983) 0.85
Small-cell variant of synovial sarcoma: fine-needle aspiration with ancillary features and potential diagnostic pitfalls. Diagn Cytopathol (2000) 0.85