Published in Int Arch Allergy Immunol on November 01, 1995
Interleukin-6 overexpression induces pulmonary hypertension. Circ Res (2008) 2.64
Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice. Respir Res (2009) 1.44
Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension. Circ Res (2014) 1.38
Angiogenic and inflammatory markers of cardiopulmonary changes in children and adolescents with sickle cell disease. PLoS One (2009) 1.07
BMP type II receptor deficiency confers resistance to growth inhibition by TGF-β in pulmonary artery smooth muscle cells: role of proinflammatory cytokines. Am J Physiol Lung Cell Mol Physiol (2012) 1.06
Nuclear factor κ-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension. PLoS One (2013) 0.91
Human herpesvirus-8 infection of primary pulmonary microvascular endothelial cells. Am J Respir Cell Mol Biol (2008) 0.83
Effects of olmesartan, an AT1 receptor antagonist, on hypoxia-induced activation of ERK1/2 and pro-inflammatory signals in the mouse lung. Naunyn Schmiedebergs Arch Pharmacol (2006) 0.82
DNA Damage and Pulmonary Hypertension. Int J Mol Sci (2016) 0.81
The effect of fetal stabilization using morphine hydrochloride on neonatal rats. Pediatr Surg Int (2007) 0.79
Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells. Respir Res (2015) 0.75
Transfer of human hepatocyte growth factor reduces inflammation and prevents pulmonary arterial remodeling in monocrotaline-induced. Int J Clin Exp Pathol (2014) 0.75
On a simple form of stromuhr. J Physiol (1912) 16.95
Formation of arrowhead complexes with heavy meromyosin in a variety of cell types. J Cell Biol (1969) 13.82
Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS. Nature (2000) 11.64
Preliminary criteria for classification of adult Still's disease. J Rheumatol (1992) 7.53
A new protein containing an SH2 domain that inhibits JAK kinases. Nature (1997) 6.28
Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. J Biol Chem (1999) 5.81
Mitosis and intermediate-sized filaments in developing skeletal muscle. J Cell Biol (1968) 5.78
Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis. J Immunol (1999) 4.77
The polymerization of actin: its role in the generation of the acrosomal process of certain echinoderm sperm. J Cell Biol (1973) 4.69
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide. J Clin Invest (2000) 4.60
The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop. EMBO J (1999) 3.77
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality. Cell (1999) 3.15
CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation. Blood (1997) 3.08
The movement of membranous organelles in axons. Electron microscopic identification of anterogradely and retrogradely transported organelles. J Cell Biol (1980) 3.08
CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation. J Exp Med (2001) 3.05
MDM2 interacts with MDMX through their RING finger domains. FEBS Lett (1999) 2.98
Negative regulation of cytokine signaling pathways. Annu Rev Immunol (2000) 2.98
Rice gibberellin-insensitive dwarf mutant gene Dwarf 1 encodes the alpha-subunit of GTP-binding protein. Proc Natl Acad Sci U S A (1999) 2.97
Spred is a Sprouty-related suppressor of Ras signalling. Nature (2001) 2.87
The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains. Mol Cell Biol (1991) 2.77
Clonal diversity and host distribution in Bordetella bronchiseptica. J Bacteriol (1987) 2.59
Plasma and pituitary concentrations of gonadotropins (FSH and LH) in minke whales (Balaenoptera acutorostrata) during the feeding season. Theriogenology (2001) 2.55
Cloning and characterization of novel CIS family genes. Biochem Biophys Res Commun (1997) 2.51
The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors. J Immunol (1999) 2.44
Infectious cell entry mechanism of influenza virus. J Virol (1982) 2.41
Generation of intestinal T cells from progenitors residing in gut cryptopatches. Science (1998) 2.32
Formation of elaborate networks of T-system tubules in cultured skeletal muscle with special reference to the T-system formation. J Cell Biol (1968) 2.30
Homodimerization and constitutive activation of the erythropoietin receptor. Proc Natl Acad Sci U S A (1992) 2.29
The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2. J Biol Chem (2001) 2.29
Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain. Genes Cells (1999) 2.28
Uncoating of influenza virus in endosomes. J Virol (1984) 2.26
Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris. J Cell Biol (1997) 2.23
Factors affecting image acquisition during scanning laser polarimetry. Ophthalmic Surg Lasers (1998) 2.23
Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7. J Biol Chem (1999) 2.21
SOCS3 is essential in the regulation of fetal liver erythropoiesis. Cell (1999) 2.19
Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes. J Clin Invest (1995) 2.16
Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis. J Clin Invest (2001) 2.15
PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex. Genes Cells (2001) 2.13
Identification of novel lymphoid tissues in murine intestinal mucosa where clusters of c-kit+ IL-7R+ Thy1+ lympho-hemopoietic progenitors develop. J Exp Med (1996) 2.06
NMR studies of a DNA containing 8-hydroxydeoxyguanosine. Nucleic Acids Res (1991) 2.03
Glomerular cell proliferation and PDGF expression precede glomerulosclerosis in the remnant kidney model. Kidney Int (1992) 2.02
Relation of interferon therapy and hepatocellular carcinoma in patients with chronic hepatitis C. Osaka Hepatocellular Carcinoma Prevention Study Group. Ann Intern Med (1998) 2.01
Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor. J Exp Med (1992) 1.98
CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2. J Biol Chem (2000) 1.97
Retinal nerve fibre layer thickness measurement reproducibility improved with spectral domain optical coherence tomography. Br J Ophthalmol (2009) 1.97
Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling. J Exp Med (2001) 1.95
Involvement of IL-6 in mesangial proliferative glomerulonephritis. J Immunol (1989) 1.89
Renal injury from angiotensin II-mediated hypertension. Hypertension (1992) 1.88
High Fas ligand expression on lymphocytes in lesions of ulcerative colitis. Gut (1998) 1.88
Effects of cytochaslasin B and colcemide on myogenic cultures. Proc Natl Acad Sci U S A (1975) 1.86
Distribution and evolution of bacteriophage WO in Wolbachia, the endosymbiont causing sexual alterations in arthropods. J Mol Evol (2000) 1.80
The Jak-Stat pathway in normal and perturbed hematopoiesis. Blood (2000) 1.78
A new quality assessment parameter for optical coherence tomography. Br J Ophthalmol (2006) 1.78
Structure, function, and activation of the erythropoietin receptor. Blood (1993) 1.77
Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteins. J Biol Chem (2001) 1.76
Electron microscopic observations of immunoreactive cells in the rheumatoid synovial membrane. Arthritis Rheum (1976) 1.75
Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-beta1 production. Oncogene (2006) 1.73
Analysis of changes in relative elemental growth rate patterns in the elongation zone of Arabidopsis roots upon gravistimulation. Planta (1998) 1.71
Functional interaction of the v-Rel and c-Rel oncoproteins with the TATA-binding protein and association with transcription factor IIB. Mol Cell Biol (1993) 1.70
SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation. Mol Cell Biol (1999) 1.69
A Janus kinase inhibitor, JAB, is an interferon-gamma-inducible gene and confers resistance to interferons. Blood (1998) 1.68
Intracellular bacterial symbionts of aphids possess many genomic copies per bacterium. J Mol Evol (1999) 1.63
Increased synthesis of extracellular matrix in mesangial proliferative nephritis. Kidney Int (1991) 1.61
Primary sclerosing cholangitis with marked eosinophilic infiltration in the liver. J Gastroenterol (1995) 1.61
Angiogenic factor. Nature (1992) 1.59
Adenosine triphosphate-dependent transport of leukotriene C4 by membrane vesicles prepared from cisplatin-resistant human epidermoid carcinoma tumor cells. J Natl Cancer Inst (1994) 1.58
EUS-guided choledochoduodenostomy for palliative biliary drainage in patients with malignant biliary obstruction: results of long-term follow-up. Endoscopy (2008) 1.57
Deficiency of serum cholesteryl-ester transfer activity in patients with familial hyperalphalipoproteinaemia. Atherosclerosis (1985) 1.55
Occurrence of chaperonin 60 and chaperonin 10 in primary and secondary bacterial symbionts of aphids: implications for the evolution of an endosymbiotic system in aphids. J Mol Evol (1993) 1.55
Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation. Oncogene (1997) 1.54
Heidelberg retina tomography and optical coherence tomography in normal, ocular-hypertensive, and glaucomatous eyes. Ophthalmology (1999) 1.53
An endonuclease activity of Escherichia coli that specifically removes 8-hydroxyguanine residues from DNA. Mutat Res (1991) 1.53
An electron microscopic study of early pathology in chondromalacia of the patella. J Bone Joint Surg Am (1988) 1.52
Safety and efficacy of granulocyte and monocyte adsorption apheresis in patients with active ulcerative colitis: a multicenter study. J Clin Apher (2001) 1.52
Adenocarcinoma arising in Barrett's esophagus after total gastrectomy. Am J Gastroenterol (1990) 1.51
In vitro replication study of modified bases in ras sequences. Chem Pharm Bull (Tokyo) (1992) 1.51
Suppressor of cytokine signaling-3 is a biomechanical stress-inducible gene that suppresses gp130-mediated cardiac myocyte hypertrophy and survival pathways. J Clin Invest (2001) 1.51
Simultaneous measurements of serum alpha-fetoprotein and protein induced by vitamin K absence for detecting hepatocellular carcinoma. South Tohoku District Study Group. Am J Gastroenterol (2000) 1.50
Diagnosis of squamous cell carcinoma arising from mature cystic teratoma of the ovary. Cancer (1998) 1.50
Cytophagic histiocytic panniculitis improved by combined CHOP and cyclosporin A treatment. Intern Med (1999) 1.49
Ultrahigh resolution optical coherence tomography in non-exudative age related macular degeneration. Br J Ophthalmol (2006) 1.49
Anti-cathepsin G antibodies in the sera of patients with ulcerative colitis. J Gastroenterol (2000) 1.49
Cytoskeletal network underlying the human erythrocyte membrane. Thin-section electron microscopy. J Cell Biol (1980) 1.48
Patterns of pancreatic metastasis from lung cancer. Anticancer Res (1998) 1.48
Molecular mechanism of introduction of the hidden break into the 28S rRNA of insects: implication based on structural studies. Nucleic Acids Res (1986) 1.48
Anaphylactoid purpura and familial IgA nephropathy. Am J Med (1989) 1.48
Organic-solvent-tolerant bacterium which secretes organic-solvent-stable lipolytic enzyme. Appl Environ Microbiol (1994) 1.47
IgG heavy chain allotypes (Gm) in autoimmune diseases. Clin Exp Immunol (1980) 1.46
Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice. Mol Cell Biol (1999) 1.45
The activated mesangial cell: a glomerular "myofibroblast"? J Am Soc Nephrol (1992) 1.44
Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activation. J Biol Chem (2001) 1.44
Sjögren's syndrome with primary biliary cirrhosis, complicated by transverse myelitis and malignant lymphoma. Intern Med (2000) 1.44
Protection against pemphigus foliaceus by desmoglein 3 in neonates. N Engl J Med (2000) 1.43
Mechanisms involved in the pathogenesis of tubulointerstitial fibrosis in 5/6-nephrectomized rats. Kidney Int (1996) 1.43
Peritoneal carcinomatosis in lung cancer patients. Oncol Rep (2001) 1.43
An autopsy case of Wegener's granulomatosis with pachymeningitis. Intern Med (1998) 1.43