Published in J Biol Chem on February 25, 1979
Mechanism of inhibition of DNA gyrase by analogues of nalidixic acid: the target of the drugs is DNA. Proc Natl Acad Sci U S A (1985) 3.18
Endogenous plasminogen activators mediate progressive intracerebral hemorrhage after traumatic brain injury in mice. Blood (2015) 1.53
Secondary-site binding of Glu-plasmin, Lys-plasmin and miniplasmin to fibrin. Biochem J (1981) 1.06
The AH-site of plasminogen and two C-terminal fragments. A weak lysine-binding site preferring ligands not carrying a free carboxylate function. Biochem J (1984) 0.99
Advances in the understanding of trauma-induced coagulopathy. Blood (2016) 0.98
Evidence that the conformation of unliganded human plasminogen is maintained via an intramolecular interaction between the lysine-binding site of kringle 5 and the N-terminal peptide. Biochem J (1998) 0.95
Positive co-operative binding at two weak lysine-binding sites governs the Glu-plasminogen conformational change. Biochem J (1992) 0.87
Skizzle is a novel plasminogen- and plasmin-binding protein from Streptococcus agalactiae that targets proteins of human fibrinolysis to promote plasmin generation. J Biol Chem (2010) 0.85
Monoclonal antibodies detect receptor-induced binding sites in Glu-plasminogen. Blood (2011) 0.85
Endothelial cell-mediated conversion of Glu-plasminogen to Lys-plasminogen. Further evidence for assembly of the fibrinolytic system on the endothelial cell surface. J Clin Invest (1988) 0.84
Folding autonomy of the kringle 4 fragment of human plasminogen. Proc Natl Acad Sci U S A (1983) 0.81
Structural/functional properties of the Glu1-HSer57 N-terminal fragment of human plasminogen: conformational characterization and interaction with kringle domains. Protein Sci (1998) 0.77
Stopped-flow fluorescence kinetics of bovine alpha 2-antiplasmin inhibition of bovine midiplasmin. Biochem J (1995) 0.76
Canine plasminogen: spectral responses to changes in 6-aminohexanoate and temperature. Anal Chem Insights (2007) 0.75
Discovery of the Fibrinolysis Inhibitor AZD6564, Acting via Interference of a Protein-Protein Interaction. ACS Med Chem Lett (2014) 0.75
Tranexamic Acid-Encapsulating Thermosensitive Liposomes for Site-Specific Pharmaco-Laser Therapy of Port Wine Stains. J Biomed Nanotechnol (2016) 0.75
Linoleic and palmitoleic acid block streptokinase-mediated plasminogen activation and reduce severity of invasive group A streptococcal infection. Sci Rep (2017) 0.75
Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG) Ann Neurol (1996) 10.39
Conformational changes in aspartate transcarbamylase. I. Proteolysis of the intact enzyme. J Biol Chem (1968) 5.34
Cellular differentiation of the immune system of mice. I. Separate splenic antigen-sensitive units for different types of anti-sheep antibody-forming cells. J Exp Med (1968) 2.51
Thromboembolism prophylaxis in chronic atrial fibrillation. Practice patterns in community and tertiary-care hospitals. Stroke (1997) 1.89
Mechanism of activation of human plasminogen by streptokinase. Presence of active center in streptokinase-plasminogen complex. J Biol Chem (1972) 1.74
Correlation of clinical, magnetic resonance imaging, and cerebrospinal fluid findings in optic neuritis. Ann Neurol (1997) 1.55
Diet and alcohol consumption and lung cancer risk in the New York State Cohort (United States) Cancer Causes Control (1997) 1.51
Cellular differentiation of the immune system of mice. V. Class differentiation in marrow precursors of plaque-forming cells. J Exp Med (1969) 1.50
Neuropsychological effects of interferon beta-1a in relapsing multiple sclerosis. Multiple Sclerosis Collaborative Research Group. Ann Neurol (2000) 1.39
Rapid assay of murine leukemia virus helper activity for Friend spleen focus-forming virus. J Natl Cancer Inst (1971) 1.37
Test-retest reliability of the cognitive lifetime drinking history. Am J Epidemiol (1997) 1.32
Cellular differentiation of the immune system of mice. IV. Lack of class differentiation in thymic antigen-reactive cells. J Exp Med (1969) 1.31
Change in antibody conformation induced by hapten. Proc Natl Acad Sci U S A (1965) 1.27
Cellular differentiation of the immune system of mice. II. Frequency of unipotent splenic antigen-sensitive units after immunization with sheep erythrocytes. J Exp Med (1969) 1.26
Quantitative determination of the binding of epsilon-aminocaproic acid to native plasminogen. J Biol Chem (1978) 1.22
Content and characterization of plasminogen activators in human lung tumors and normal lung tissue. Cancer Res (1980) 1.17
Protein substrate conformation and proteolysis. Proc Natl Acad Sci U S A (1965) 1.16
Localization of plasminogen activators in human colon cancer by immunoperoxidase staining. Cancer Res (1985) 1.15
Brain MRI lesions and atrophy are related to depression in multiple sclerosis. Neuroreport (2000) 1.15
Impact of interferon beta-1a on neurologic disability in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG). Neurology (1997) 1.14
Information in natural languages. A new approach. JAMA (1969) 1.13
Comparison of some properties of native (Glu) and modified (Lys) human plasminogen. J Biol Chem (1978) 1.12
Prospective evaluation of the Ottawa Ankle Rules in a university sports medicine center. With a modification to increase specificity for identifying malleolar fractures. Am J Sports Med (1998) 1.12
Plasminogen activator secretion of human tumors in short-term organ culture, including a comparison of primary and metastatic colon tumors. Cancer Res (1983) 1.07
Antibiotic use, hospital admissions, and mortality before and after implementing guidelines for nursing home-acquired pneumonia. J Am Geriatr Soc (2001) 1.06
Affinity chromatography of thymidine kinase from a rat colon adenocarcinoma. Prep Biochem (1976) 1.05
A statistical method for the estimation of binding parameters in a complex system. Anal Biochem (1976) 1.03
The role of hemostasis and fibrinolysis in the metastatic spread of cancer. Semin Thromb Hemost (1984) 1.02
Plasminogen activator activity and composition in human breast cancer. Cancer Res (1982) 1.01
Conformational changes in aspartate transcarbamylase. 3. A functional model for allosteric behavior. J Biol Chem (1971) 1.01
Cerebrospinal fluid abnormalities in a phase III trial of Avonex (IFNbeta-1a) for relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group. J Neuroimmunol (1999) 1.00
Plasminogen activator content of human colon tumors and normal mucosae: separation of enzymes and partial purification. J Natl Cancer Inst (1980) 0.97
Personality disorder in multiple sclerosis correlates with cognitive impairment. J Neuropsychiatry Clin Neurosci (2001) 0.96
Prognostic factors in patients with advanced stage prostate cancer. Cancer Res (1985) 0.96
Relative reliability of five serially measured markers for prognosis of progression in prostate cancer. J Natl Cancer Inst (1986) 0.96
Plasminogen activator content and secretion in explants of neoplastic and benign human prostate tissues. Cancer Res (1984) 0.94
Treatment of advanced ovarian carcinoma in the elderly. Gynecol Oncol (1993) 0.93
Ligand-induced conformational changes in ribonuclease. J Biol Chem (1968) 0.93
Phosphoenolpyruvate carboxylase of Escherichia coli. Purification and some properties. J Biol Chem (1972) 0.92
Interference with dimethylhydrazine induction of colon tumors in mice by epsilon-aminocaproic acid. Science (1982) 0.91
A genetic analysis of melanoma--polygenic inheritance as a threshold trait. Am J Epidemiol (1981) 0.90
Demonstration of urokinase expression in cancer cells of colon adenocarcinomas by immunohistochemistry and in situ hybridization. Am J Pathol (1999) 0.89
Plasminogen activator content of neoplastic and benign human prostate tissues; fibrin augmentation of an activator activity. Int J Cancer (1981) 0.88
Oxygen Transport. Science (1960) 0.88
Activator activities of the transient forms of the human plasminogen-streptokinase complex during its proteolytic conversion to the stable activator complex. J Biol Chem (1976) 0.87
The Ordac method of making age adjustments in data. J Chronic Dis (1964) 0.87
Esterase activities in the zymogen moiety of the streptokinase-plasminogen complex. J Biol Chem (1974) 0.86
Capsular polysaccharide and O-specific antigen divergently modulate pulmonary neutrophil influx in an Escherichia coli model of gram-negative pneumonitis in rats. Infect Immun (2000) 0.86
Urokinase-like plasminogen activators of unusually high molecular weight secreted by a cell line derived from a human lung cancer case. J Biol Chem (1982) 0.85
Conformational changes in aspartate transcarbamylase. II. Concerted or sequential mechanism? J Biol Chem (1969) 0.84
Cigarette smoking and periodontal disease. J Am Dent Assoc (1968) 0.84
Recognition of drug resistance during remission induction therapy for acute non-lymphocytic leukemia: utility of day 6 bone marrow biopsy. Leuk Res (1983) 0.83
Directed migration of murine and human tumor cells to collagenases and other proteases. Cancer Res (1989) 0.83
Transcortin. A corticosteroid-binding protein of plasma. IX. Isolation and characterization. Biochemistry (1966) 0.83
Plasminogen activators in human malignant melanoma. J Natl Cancer Inst (1984) 0.83
Secretion of plasminogen activators by human colorectal and gastric tumor explants. Clin Exp Metastasis (1988) 0.82
Effect of immunization with common enterobacterial antigen on experimental Salmonella typhimurium infection of mice. Immunol Commun (1972) 0.82
Prostatic cancer. Treated at a categorical center, 1980-1983. Urology (1986) 0.82
Relationship between leukemic cell retention of cytosine arabinoside triphosphate and the duration of remission in patients with acute non-lymphocytic leukemia. Eur J Cancer Clin Oncol (1985) 0.81
Heteroagglutinins of the horseshoe crab Limulus polyphemus. Life Sci (1965) 0.81
Ligand-stabilized conformations in serum albumin. J Biol Chem (1967) 0.81
Tryptic hydrolysis of human serum albumin. The pattern of initial fragmentation. J Biol Chem (1967) 0.80
Comparability of nutrient estimation by three food frequency questionnaires for use in epidemiological studies. Nutr Cancer (1999) 0.80
Using a mathematical model in the evaluation of human tumor response to chemotherapy. J Natl Cancer Inst (1966) 0.80
ROSFIT: an enzyme kinetics nonlinear regression curve fitting package for a microcomputer. Comput Biomed Res (1982) 0.79
Cancer cells release a covalent complex containing disulfide-linked domains from urinary plasminogen activator, neural cell adhesion molecule, and haptoglobin alpha and beta chains. Arch Biochem Biophys (1997) 0.79
Comparing the ability of various compositive outcomes to discriminate treatment effects in MS clinical trials. The Multiple Sclerosis Collaborative Research Group (MSCRG). Mult Scler (1998) 0.79
Screening for atrial fibrillation in the community: a multicenter validation trial. J Stroke Cerebrovasc Dis (2007) 0.78
Augmentation of streptokinase activator activity by fibrinogen or fibrin. Thromb Res (1980) 0.78
Statistical analysis of data from countercurrent distribution. 3. The biliary and urinary excretion patterns of estriol in a human subject. Steroids (1968) 0.78
Statistical analysis of data from countercurrent distribution. II. Some applications and limitations of the method. Anal Biochem (1968) 0.78
Epidermal growth factor and 12-tetradecanoyl phorbol 13-acetate induction of urokinase in A431 cells. Semin Thromb Hemost (1991) 0.77
Potentiation of thrombolytic therapy by enzyme combinations and with aspirin or pentoxifylline. J Med (1994) 0.77
Statistical analysis of data from countercurrent distribution. I. Method for estimation of quantity and partition coefficient of each compound in the distribution. Anal Biochem (1968) 0.77
Mechanism(S) of interferon inhibitory activity in blood from patients with AIDS and patients with lupus erythematosus with vasculitis. Res Commun Mol Pathol Pharmacol (1997) 0.76
Impact of interferon beta-1a on neurologic disability in relapsing multiple sclerosis. 1997. Neurology (2001) 0.76
Postoperative respiratory complications in patients with Hodgkin's disease: relationship to the size of the mediastinal tumor. Eur J Cancer Clin Oncol (1985) 0.76
Prostate cancer mortality among Catholic priests. J Surg Oncol (1981) 0.75
A comparison of estrogen and androgen receptor levels in human prostatic tissue from patients with non-metastatic and metastatic carcinoma and benign prostatic hyperplasia. J Steroid Biochem (1985) 0.75
Bombesin antagonist prevents CO2 laser-induced promotion of oral cancer. Proc Natl Acad Sci U S A (1996) 0.75
A new method for plasminogen standardization. Thromb Diath Haemorrh (1968) 0.75
Feasibility of automated information systems in the users' natural language. Am Sci (1969) 0.75
Statistical analysis of data from countercurrent distribution. V. The isotope effect. Anal Biochem (1970) 0.75
Further evidence for an active center in streptokinase-plasminogen complex; interaction with pancreatic trypsin inhibitor. Biochem Biophys Res Commun (1973) 0.75
[The inborn ear fistula in the horse]. Dtsch Tierarztl Wochenschr (1974) 0.75
Statistical analysis of data from Countercurrent distribution. IV. Identification of compounds. Anal Biochem (1970) 0.75
Kinetic properties of thymidine kinase from the cytosol of a rat colon adenocarcinoma. J Med (1982) 0.75
Phase I trial and pharmacokinetics of a daily x 5 schedule of 3-deazauridine. Cancer Treat Rep (1982) 0.75
Anion-specific effects on the streptokinase activation of human plasminogen. J Biol Chem (1968) 0.75
U.S. centralized cancer patient data system for uniform communication among cancer centers. J Natl Cancer Inst (1981) 0.75
A hydrocarbon-soluble protein-lipid complex: characterization by chemical analysis, ultracentrifugation and electron microscopy. Biochim Biophys Acta (1970) 0.75
Carcinogenic activity of smoke condensate from cigarettes with ammonium sulfamate-treated paper. Cancer (1974) 0.75
Epidemiology of survival from cancer of the cervix. J Natl Cancer Inst (1972) 0.75
Cancer of the tongue. Comments on surgical treatment. Am J Surg (1966) 0.75
Antitumor activity of Corynebacterium parvum and retinyl palmitate used in combination on the Lewis lung carcinoma. Cancer Res (1980) 0.75
Systemization of scatchard or Lineweaver-Burk plot linearization: application to receptor analysis. Prog Clin Biol Res (1979) 0.75
Conformational changes in aspartate transcarbamylase. IV. Ligand effects on intersubunit interactions. J Biol Chem (1972) 0.75
Automated multiphasic laboratory screening in cancer population. N Y State J Med (1972) 0.75