Published in Drug Metab Dispos on March 01, 1995
Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. J Clin Invest (1998) 2.62
Lamotrigine dosing for pregnant patients with bipolar disorder. Am J Psychiatry (2013) 1.79
Drug metabolism and transport during pregnancy: how does drug disposition change during pregnancy and what are the mechanisms that cause such changes? Drug Metab Dispos (2013) 1.27
Antiepileptic drug interactions - principles and clinical implications. Curr Neuropharmacol (2010) 1.27
Lamotrigine pharmacokinetic evaluation in epileptic patients submitted to VEEG monitoring. Eur J Clin Pharmacol (2006) 0.77
Ganoderic acid B's influence towards the therapeutic window of trifluoperazine (TFP). Afr Health Sci (2015) 0.76
OleD Loki as a Catalyst for Tertiary Amine and Hydroxamate Glycosylation. Chembiochem (2017) 0.75
Determination of lamotrigine in human serum by high-performance liquid chromatography–tandem mass spectrometry. Neurol Sci (2010) 0.75
In vitro glucuronidation of aprepitant: a moderate inhibitor of UGT2B7. Xenobiotica (2015) 0.75
A case of intention tremor induced by the combination of aripiprazole and lamotrigine. Prim Care Companion CNS Disord (2012) 0.75
Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. J Clin Invest (1998) 2.62
The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics (1997) 2.55
UDP-glucuronosyltransferases. Curr Drug Metab (2000) 1.94
Efficacy and optimal dose of daily polyethylene glycol 3350 for treatment of constipation and encopresis in children. J Pediatr (2001) 1.91
Increased urinary excretion of 3-hydroxyisovaleric acid and decreased urinary excretion of biotin are sensitive early indicators of decreased biotin status in experimental biotin deficiency. Am J Clin Nutr (1997) 1.66
The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268). Drug Metab Dispos (1998) 1.58
Methanol poisoning in human subjects. Role for formic acid accumulation in the metabolic acidosis. Am J Med (1980) 1.49
Studies on the mechanism of experimental porphyria produced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Role of a porphyrin-like inhibitor of protohaem ferro-lyase. Biochem J (1979) 1.46
Methanol poisoning: ocular toxicity produced by formate. Toxicol Appl Pharmacol (1978) 1.42
The effect of cobalt chloride administration on the synthesis of hepatic microsomal cytochrome P-450. Biochem Biophys Res Commun (1971) 1.41
Human UGT2B7 catalyzes morphine glucuronidation. Drug Metab Dispos (1997) 1.40
Effect of 3-amino-1,2,4-triazole on the stimulation of hepatic microsomal heme synthesis and induction of hepatic microsomal oxidases produced by phenobarbital. Mol Pharmacol (1969) 1.35
Separation, purification and characterization of three isoenzymes of UDP-glucuronyltransferase from rat liver microsomes. Arch Biochem Biophys (1983) 1.31
Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene. Pharmacogenetics (1997) 1.31
Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7. J Steroid Biochem Mol Biol (1999) 1.24
3'-azido-3'-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7). Drug Metab Dispos (2000) 1.20
UDP-glucuronosyltransferase activities. Guidelines for consistent interim terminology and assay conditions. Biochem Pharmacol (1983) 1.14
Morphine metabolism. III. Solubilization and separation of morphine and p-nitrophenol uridine diphosphoglucuronyltransferases. Mol Pharmacol (1975) 1.13
Camphor hepatotoxicity. South Med J (2000) 1.12
Effect of drugs on heme synthesis in the liver. Metabolism (1971) 1.12
4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7. J Biol Chem (2000) 1.11
Methyl alcohol poisoning III. Ocular toxicity. Arch Ophthalmol (1977) 1.10
Glucuronidation of amines and hydroxylated xenobiotics and endobiotics catalyzed by expressed human UGT1.4 protein. Drug Metab Dispos (1996) 1.10
Glucuronidation of 6 alpha-hydroxy bile acids by human liver microsomes. J Clin Invest (1987) 1.09
Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3. Drug Metab Dispos (1998) 1.09
Identification of N-methylprotoporphyrin IX in livers of untreated mice and mice treated with 3, 5-diethoxycarbonyl- 1, 4-dihydrocollidine: source of the methyl group. Arch Biochem Biophys (1981) 1.06
Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteins. Drug Metab Dispos (1998) 1.06
Morphine metabolism. I. Evidence for separate enzymes in the glucuronidation of morphine and p-nitrophenol by rat hepatic microsomes. Drug Metab Dispos (1974) 1.05
Methanol poisoning. V. Role of formate metabolism in the monkey. J Pharmacol Exp Ther (1977) 1.03
The regulation of heme synthesis related to drug metabolism. Drug Metab Dispos (1974) 1.02
Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates. Drug Metab Dispos (1995) 1.02
Isolation and characterization of multiple forms of rat liver UDP-glucuronate glucuronosyltransferase. Biochem J (1986) 1.02
Inhibition of protohaem ferro-lyase in experimental porphyria. Isolation and partial characterization of a modified porphyrin inhibitor. Biochem J (1980) 1.02
Methyl alcohol poisoning. IV. Alterations of the morphological findings of the retina and optic nerve. Arch Ophthalmol (1977) 1.02
Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10. Drug Metab Dispos (1999) 1.01
Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved. Carcinogenesis (1999) 1.01
Glucuronidation of catechol estrogens by expressed human UDP-glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7. Toxicol Sci (1998) 1.00
Further studies on the relationship of the stimulatory effects of phenobarbital and 3,4-benzpyrene on hepatic heme synthesis to their effects on hepatic microsomal drug oxidations. Arch Biochem Biophys (1970) 1.00
Separation of oestrone UDP-glucuronyltransferase and p-nitrophenol UDP-glucuronyltransferase activities. Biochem J (1978) 0.99
The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1. Arch Biochem Biophys (1996) 0.99
Formate assay in body fluids: application in methanol poisoning. Biochem Med (1975) 0.97
Methyl alcohol poisoning. II. Development of a model for ocular toxicity in methyl alcohol poisoning using the rhesus monkey. Arch Ophthalmol (1977) 0.96
Improved estimation of formate in body fluids and tissues. Clin Chem (1982) 0.96
Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate. Arch Biochem Biophys (1999) 0.95
UDP-glucuronosyltransferases in human intestinal mucosa. Biochim Biophys Acta (1998) 0.94
Formaldehyde poisoning. Rapid metabolism to formic acid. JAMA (1981) 0.94
Glucuronidation of bile acids by rat liver 3-OH androgen UDP-glucuronyltransferase. J Biol Chem (1984) 0.94
High-pressure liquid chromatography separation and determination of rat liver folates. Arch Biochem Biophys (1981) 0.93
Morphine metabolism. II. Studies on morphine glucuronyltransferase activity in intestinal microsomes of rats. Drug Metab Dispos (1974) 0.92
Methanol toxicity: treatment with folic acid and 5-formyl tetrahydrofolic acid. Alcohol Clin Exp Res (1980) 0.92
Methanol poisoning. I. The role of formic acid in the development of metabolic acidosis in the monkey and the reversal by 4-methylpyrazole. Biochem Med (1975) 0.91
The role of heme synthesis during the induction of hepatic microsomal cytochrome P-450 and drug metabolism produced by benzpyrene. Biochem Biophys Res Commun (1969) 0.91
The role of hepatic microbody and soluble oxidases in the peroxidation of methanol in the rat and monkey. Mol Pharmacol (1968) 0.91
Studies on the mechanism of methanol poisoning: purification and comparison of rat and human liver 10-formyltetrahydrofolate dehydrogenase. Mol Pharmacol (1989) 0.90
Methanol poisoning and formate oxidation in nitrous oxide-treated rats. J Pharmacol Exp Ther (1981) 0.90
Morphine metabolism. V. Isolation of separate glucuronyltransferase activities for morphine and p-nitrophenol from rabbit liver microsomes. Drug Metab Dispos (1977) 0.90
The enzymatic mechanism of glucuronidation catalyzed by two purified rat liver steroid UDP-glucuronosyltransferases. J Biol Chem (1987) 0.90
Steroid 3- and 17-OH UDP-glucuronosyltransferase activities in rat and rabbit liver microsomes. Drug Metab Dispos (1983) 0.90
Folate and 10-formyltetrahydrofolate dehydrogenase (FDH) expression in the central nervous system of the mature rat. Brain Res (1997) 0.89
Purification of properties of rabbit liver estrone and p-nitrophenol UDP-glucuronyltransferases. Arch Biochem Biophys (1981) 0.89
Isolation and purification of two human liver UDP-glucuronosyltransferases. Mol Pharmacol (1987) 0.89
Blood methanol concentrations in normal adult subjects administered abuse doses of aspartame. J Toxicol Environ Health (1981) 0.88
Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8. Arch Biochem Biophys (1998) 0.88
Studies on methanol toxicity and formate metabolism in isolated hepatocytes. The role of methionine in folate-dependent reactions. Biochem Pharmacol (1979) 0.88
Role of hepatic tetrahydrofolate in the species difference in methanol toxicity. Proc Natl Acad Sci U S A (1985) 0.87
UDP glucuronosyltransferase in the cirrhotic rat liver. J Gastroenterol Hepatol (1996) 0.86
delta-Aminolevulinic acid synthetase-sensitive methods in liver for hemoprotein biosynthesis. Methods Enzymol (1978) 0.86
Substrate specificity and characterization of rat liver p-nitrophenol, 3 alpha-hydroxysteroid and 17 beta-hydroxysteroid UDP-glucuronosyltransferases. Biochem J (1986) 0.86
Methanol toxicity in the monkey: effects of nitrous oxide and methionine. J Pharmacol Exp Ther (1983) 0.86
Lack of a role for formaldehyde in methanol poisoning in the monkey. Biochem Pharmacol (1979) 0.86
Comparison of stably expressed rat UGT1.1 and UGT2B1 in the glucuronidation of opioid compounds. Drug Metab Dispos (1997) 0.86
Inhibition of drug metabolism. V. Inhibition of drug metabolism by steroids. Mol Pharmacol (1968) 0.86
The role of substrates for glycine acyltransferase, and the role of sulfanilamide and acetate in the reversal of chemically-induced porphyria in the rat. Enzyme (1973) 0.85
The role of methionine in regulating folate-dependent reactions in isolated rat hepatocytes. Arch Biochem Biophys (1981) 0.85
Isolation and purification of rat liver morphine UDP-glucuronosyltransferase. Mol Pharmacol (1986) 0.84
Phospholipid-dependence of oestrone UDP-glucuronyltransferase and p-nitrophenol UDP-glucuronyltransferase. Biochem J (1979) 0.84
Structural requirements in the reaction of morphine uridine diphosphate glucuronyltransferase with opioid substances. Biochem J (1978) 0.84
The formation of N-alkylprotoporphyrin IX and destruction of cytochrome P-450 in the liver of rats after treatment with 3,5-diethoxycarbonyl-1,4-dihydrocollidine and its 4-ethyl analog. Arch Biochem Biophys (1982) 0.84
Methanol poisoning in the folate-deficient rat. Nature (1976) 0.84
Metabolism of formate in the rat. J Toxicol Environ Health (1975) 0.83
Characterization and primary sequence of a human hepatic microsomal estriol UDPglucuronosyltransferase. Arch Biochem Biophys (1990) 0.83
Identification of cobalt protoporphyrin IX formation in vivo following cobalt administration to rats. Biochem Pharmacol (1980) 0.83
Comparative N-glucuronidation kinetics of ketotifen and amitriptyline by expressed human UDP-glucuronosyltransferases and liver microsomes. Drug Metab Dispos (2000) 0.83
Studies on the mechanism of experimental porphyria and ferrochelatase inhibition produced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Int J Biochem (1980) 0.83
A comparison of rat and human liver formaldehyde dehydrogenase. Biochim Biophys Acta (1971) 0.83
Effects of metals on heme biosynthesis and metabolism. Fed Proc (1978) 0.83
Cloning and stable expression of a cDNA encoding a rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 1.1) that catalyzes the glucuronidation of opioids and bilirubin. Mol Pharmacol (1995) 0.83
Role of the intracellular distribution of hepatic catalase in the peroxidative oxidation of methanol. Ann N Y Acad Sci (1969) 0.82
Caco-2 cells express type I interleukin-1 receptors: ligand binding enhances proliferation. Am J Physiol (1994) 0.82
A possible role of copper in the regulation of heme biosynthesis through ferrochelatase. Adv Exp Med Biol (1975) 0.82
Studies on the role of folic acid and folate-dependent enzymes in human methanol poisoning. Mol Pharmacol (1987) 0.82
Ursodeoxycholic acid improves cholestasis in infants with cystic fibrosis. Ann Pharmacother (1997) 0.82
Analysis of opioid binding to UDP-glucuronosyltransferase 2B7 fusion proteins using nuclear magnetic resonance spectroscopy. Mol Pharmacol (2001) 0.82
Separation, purification, and characterization of digitoxigenin-monodigitoxoside UDP-glucuronosyltransferase activity. Drug Metab Dispos (1986) 0.82
A procedure for the rapid separation and purification of UDP-glucuronosyltransferases from rabbit liver microsomes. Drug Metab Dispos (1982) 0.82
Nerve growth factor synthesis by intestinal epithelial cells. Am J Physiol (1995) 0.81
Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by rat UDP-glucuronosyltransferase 2B1. Drug Metab Dispos (1999) 0.81
The reversal of experimental porphyria and the prevention of induction of hepatic mixed-function oxidase by acetate. Arch Biochem Biophys (1974) 0.81
Safety of long-term large doses of aspartame. Arch Intern Med (1989) 0.81