Published in Nature on August 17, 1995
Molecular genetics of the RNA polymerase II general transcriptional machinery. Microbiol Mol Biol Rev (1998) 4.49
DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone. Proc Natl Acad Sci U S A (1998) 3.49
New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB. Genes Dev (1998) 3.45
Orientation of the transcription preinitiation complex in archaea. Proc Natl Acad Sci U S A (1999) 1.84
A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains. EMBO J (1996) 1.81
High-resolution mapping of nucleoprotein complexes by site-specific protein-DNA photocrosslinking: organization of the human TBP-TFIIA-TFIIB-DNA quaternary complex. Proc Natl Acad Sci U S A (1996) 1.78
TFIIB and the regulation of transcription by RNA polymerase II. Chromosoma (2007) 1.53
Protein-protein interactions in eukaryotic transcription initiation: structure of the preinitiation complex. Proc Natl Acad Sci U S A (1996) 1.50
Architecture of protein and DNA contacts within the TFIIIB-DNA complex. Mol Cell Biol (1998) 1.28
Functional interaction between TFIIB and the Rpb9 (Ssu73) subunit of RNA polymerase II in Saccharomyces cerevisiae. Nucleic Acids Res (1996) 1.27
Promoter-specific shifts in transcription initiation conferred by yeast TFIIB mutations are determined by the sequence in the immediate vicinity of the start sites. Mol Cell Biol (2001) 1.27
The Dr1/DRAP1 heterodimer is a global repressor of transcription in vivo. Proc Natl Acad Sci U S A (1997) 1.23
DNA bending by the silencer protein NeP1 is modulated by TR and RXR. Nucleic Acids Res (1996) 1.20
TFIIB-directed transcriptional activation by the orphan nuclear receptor hepatocyte nuclear factor 4. Mol Cell Biol (1996) 1.20
Bidirectional binding of the TATA box binding protein to the TATA box. Proc Natl Acad Sci U S A (1997) 1.18
A new class of activation-defective TATA-binding protein mutants: evidence for two steps of transcriptional activation in vivo. Mol Cell Biol (1996) 1.18
A severely defective TATA-binding protein-TFIIB interaction does not preclude transcriptional activation in vivo. Mol Cell Biol (1997) 1.16
Identifying a species-specific region of yeast TF11B in vivo. Mol Cell Biol (1996) 1.01
Transcriptional activation by TFIIB mutants that are severely impaired in interaction with promoter DNA and acidic activation domains. Mol Cell Biol (1997) 0.96
Roles for non-TATA core promoter sequences in transcription and factor binding. Mol Cell Biol (2000) 0.94
Role of TATA box sequence and orientation in determining RNA polymerase II/III transcription specificity. Nucleic Acids Res (1996) 0.86
TATA elements direct bi-directional transcription by RNA polymerases II and III. Nucleic Acids Res (1996) 0.81
Five intermediate complexes in transcription initiation by RNA polymerase II. Cell (1989) 9.22
Crystal structure of a yeast TBP/TATA-box complex. Nature (1993) 7.95
Ageing, fitness and neurocognitive function. Nature (1999) 5.58
An operator at -280 base pairs that is required for repression of araBAD operon promoter: addition of DNA helical turns between the operator and promoter cyclically hinders repression. Proc Natl Acad Sci U S A (1984) 5.42
Each of three "TATA elements" specifies a subset of the transcription initiation sites at the CYC-1 promoter of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1985) 4.69
Function of a yeast TATA element-binding protein in a mammalian transcription system. Nature (1988) 3.91
A transcription reinitiation intermediate that is stabilized by activator. Nature (2000) 3.65
Crystal structure of the yeast TFIIA/TBP/DNA complex. Science (1996) 3.45
Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism. Genes Dev (1994) 3.45
The use of unequal randomisation ratios in clinical trials: a review. Contemp Clin Trials (2005) 2.98
Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB. Genes Dev (1999) 2.94
A yeast and a human CCAAT-binding protein have heterologous subunits that are functionally interchangeable. Cell (1988) 2.84
Variants of the TATA-binding protein can distinguish subsets of RNA polymerase I, II, and III promoters. Cell (1992) 2.76
Yeast HAP2 and HAP3 activators both bind to the CYC1 upstream activation site, UAS2, in an interdependent manner. Cell (1987) 2.73
The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo. Genes Dev (1998) 2.72
Long-term (6 and 12 months) follow-up of two prospective, randomized, controlled phase III trials of photodynamic therapy with BF-200 ALA and methyl aminolaevulinate for the treatment of actinic keratosis. Br J Dermatol (2013) 2.70
The role of the TATA-binding protein in the assembly and function of the multisubunit yeast RNA polymerase III transcription factor, TFIIIB. Cell (1992) 2.69
Recruitment of the SWI/SNF chromatin remodeling complex by transcriptional activators. Genes Dev (1999) 2.48
Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity. J Immunol (1994) 2.41
Task coordination and aging: explorations of executive control processes in the task switching paradigm. Acta Psychol (Amst) (1999) 2.22
An ATP-dependent inhibitor of TBP binding to DNA. Genes Dev (1993) 2.19
A yeast TFIIB-related factor involved in RNA polymerase III transcription. Genes Dev (1992) 2.17
The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta (1995) 2.06
Dominant negative mutations in yeast TFIID define a bipartite DNA-binding region. Cell (1991) 1.91
Differences in the glucose-lowering efficacy of dipeptidyl peptidase-4 inhibitors between Asians and non-Asians: a systematic review and meta-analysis. Diabetologia (2013) 1.88
Upstream repression and CRP stimulation of the Escherichia coli L-arabinose operon. J Mol Biol (1984) 1.84
Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA. Nature (1994) 1.80
Fetal gender and aneuploidy detection using fetal cells in maternal blood: analysis of NIFTY I data. National Institute of Child Health and Development Fetal Cell Isolation Study. Prenat Diagn (2002) 1.74
Transcription of Escherichia coli ara in vitro. The cyclic AMP receptor protein requirement for PBAD induction that depends on the presence and orientation of the araO2 site. J Mol Biol (1986) 1.67
The region of phage T4 genes 34, 33 and 59: primary structures and organization on the genome. Nucleic Acids Res (1986) 1.66
Molecular analysis of the SNF2/SWI2 protein family member MOT1, an ATP-driven enzyme that dissociates TATA-binding protein from DNA. Mol Cell Biol (1997) 1.58
Severely reduced presence of tissue macrophages in the basal plate of pre-eclamptic placentae. Placenta (2001) 1.58
Influence of attentional capture on oculomotor control. J Exp Psychol Hum Percept Perform (1999) 1.57
Detection of hypoxia in human squamous cell carcinoma by EF5 binding. Cancer Res (2000) 1.53
[S3-Guidelines "Exocrine pancreatic cancer" 2007]. Z Gastroenterol (2007) 1.52
Isolation of two genes that encode subunits of the yeast transcription factor IIA. Science (1992) 1.49
Preterm birth and the availability of cord blood for HPC transplantation. Transfusion (2000) 1.47
Functional hierarchy of AUUUA motifs in mediating rapid interleukin-3 mRNA decay. J Biol Chem (1994) 1.46
Photodynamic therapy in the canine prostate using motexafin lutetium. Clin Cancer Res (2001) 1.43
Yeast nuclear extract contains two major forms of RNA polymerase II mediator complexes. J Biol Chem (2001) 1.42
The yeast general transcription factor TFIIA is composed of two polypeptide subunits. J Biol Chem (1991) 1.40
Cloning and functional characterization of the gene encoding the TFIIIB90 subunit of RNA polymerase III transcription factor TFIIIB. J Biol Chem (1996) 1.37
Gender, quality of life, and mental disorders in primary care: results from the PRIME-MD 1000 study. Am J Med (1996) 1.37
In vivo regulation of the Escherichia coli araC promoter. J Bacteriol (1983) 1.36
Pancreatic intraepithelial neoplasia revisited and updated. Pancreatology (2008) 1.35
Analysis of the yeast transcription factor TFIIA: distinct functional regions and a polymerase II-specific role in basal and activated transcription. Mol Cell Biol (1995) 1.35
Repression of KIAA1199 attenuates Wnt-signalling and decreases the proliferation of colon cancer cells. Br J Cancer (2011) 1.32
Accuracy of radiographer plain radiograph reporting in clinical practice: a meta-analysis. Clin Radiol (2005) 1.31
Architecture of protein and DNA contacts within the TFIIIB-DNA complex. Mol Cell Biol (1998) 1.28
[Medical ethics in the life of a physician of the soul--reflections on the medical ethics concept of Albert Moll (1862-1936)]. Z Gesamte Inn Med (1984) 1.24
Psychiatric comorbidity, health status, and functional impairment associated with alcohol abuse and dependence in primary care patients: findings of the PRIME MD-1000 study. J Consult Clin Psychol (1995) 1.23
Investigation of coronary venous anatomy by retrograde venography in patients with malignant ventricular tachycardia. Circulation (2001) 1.22
Elevation of both maternal and fetal extracellular circulating deoxyribonucleic acid concentrations in the plasma of pregnant women with preeclampsia. Am J Obstet Gynecol (2001) 1.19
Biliary glycoprotein (CD66a), a cell adhesion molecule of the immunoglobulin superfamily, on human lymphocytes: structure, expression and involvement in T cell activation. Eur J Immunol (1998) 1.15
The neural correlates of driving. Neuroreport (2001) 1.15
Attentional capture and aging: implications for visual search performance and oculomotor control. Psychol Aging (1999) 1.14
Age differences in the control of looking behavior: do you know where your eyes have been? Psychol Sci (2000) 1.14
Fetal DNA in maternal plasma is elevated in pregnancies with aneuploid fetuses. Prenat Diagn (2000) 1.14
The Fas receptor in HIV infection: expression on peripheral blood lymphocytes and role in the depletion of T cells. AIDS (1996) 1.14
Transvenous biventricular defibrillation halves energy requirements in patients. Circulation (2001) 1.12
Differences in the HbA1c-lowering efficacy of glucagon-like peptide-1 analogues between Asians and non-Asians: a systematic review and meta-analysis. Diabetes Obes Metab (2014) 1.12
Ketamine-xylazine anaesthesia blocks consolidation of ocular dominance changes in kitten visual cortex. Nature (1987) 1.12
The effect of labour and placental separation on the shedding of syncytiotrophoblast microparticles, cell-free DNA and mRNA in normal pregnancy and pre-eclampsia. Placenta (2008) 1.08
Feto-maternal interactions in pregnancies: placental microparticles activate peripheral blood monocytes. Placenta (2009) 1.07
Reduced osmolarity oral rehydration solution for treating cholera. Cochrane Database Syst Rev (2004) 1.07
Disturbed feto-maternal cell traffic in preeclampsia. Obstet Gynecol (1998) 1.07
Antibiotic treatment for travellers' diarrhoea. Cochrane Database Syst Rev (2000) 1.03
Usefulness of the carina as a radiographic landmark for central venous catheter placement in paediatric patients. Br J Anaesth (2005) 1.02
Psychological implications of infertility in women with polycystic ovary syndrome. Hum Reprod (2008) 1.02
Attentional and oculomotor capture by onset, luminance and color singletons. Vision Res (2000) 1.02
Transcription: basal factors and activation. Curr Opin Genet Dev (1996) 1.01
Aberrations of early trophoblast differentiation predispose to pregnancy failure: lessons from the anti-phospholipid syndrome. Placenta (2005) 1.01
Anticipation in familial pancreatic cancer. Gut (2005) 1.00
Detection of fetal Rhesus D and sex using fetal DNA from maternal plasma by multiplex polymerase chain reaction. BJOG (2000) 0.99
Effects of obesity on neuroendocrine, cardiovascular, and immune cell responses to acute psychosocial stress in premenopausal women. Psychoneuroendocrinology (2008) 0.98
TFIIIC determines RNA polymerase III specificity at the TATA-containing yeast U6 promoter. Genes Dev (1995) 0.98
[Basic principles of successful implantation of the SB Charité model LINK intervertebral disk endoprosthesis]. Orthopade (2002) 0.97
Neuropsychologic dysfunction in women following leuprolide acetate induction of hypoestrogenism. J Assist Reprod Genet (1993) 0.96
Cell-free DNA in urine: a marker for kidney graft rejection, but not for prenatal diagnosis? Ann N Y Acad Sci (2001) 0.95
A comparative study of the effect of three different syncytiotrophoblast micro-particles preparations on endothelial cells. Placenta (2005) 0.95
Psychotherapy intervention to reduce depressive symptoms in patients with diabetic foot syndrome. Diabet Med (2008) 0.95
Rec (formerly Corf) function requires interaction with a complex, folded RNA structure within its responsive element rather than binding to a discrete specific binding site. J Virol (2001) 0.95
Reduced osmolarity oral rehydration solution for treating dehydration caused by acute diarrhoea in children. Cochrane Database Syst Rev (2001) 0.95
Whole-body FDG PET/CT is more accurate than conventional imaging for staging primary breast cancer patients. Eur J Nucl Med Mol Imaging (2012) 0.95
Disturbed stress responses in women with polycystic ovary syndrome. Psychoneuroendocrinology (2009) 0.94
Risk free simultaneous prenatal identification of fetal Rhesus D status and sex by multiplex real-time PCR using cell free fetal DNA in maternal plasma. Swiss Med Wkly (2001) 0.93
Circulatory fetal and maternal DNA in pregnancies at risk and those affected by preeclampsia. Ann N Y Acad Sci (2001) 0.93
Obesity, depression, and chronic low-grade inflammation in women with polycystic ovary syndrome. Brain Behav Immun (2007) 0.93
CD4+ T cell-mediated killing of major histocompatibility complex class II-positive antigen-presenting cells (APC). III. CD4+ cytotoxic T cells induce apoptosis of APC. Eur J Immunol (1992) 0.93
Radiographers and radiologists reporting plain radiograph requests from accident and emergency and general practice. Clin Radiol (2005) 0.92
Prevalence and implications of anxiety in polycystic ovary syndrome: results of an internet-based survey in Germany. Hum Reprod (2009) 0.92
[Medial hip neck fracture: influence of pre-operative delay on the quality of outcome. Results of data from the external in-hospital quality assurance within the framework of secondary data analysis]. Unfallchirurg (2010) 0.90
Accuracy of radiographers red dot or triage of accident and emergency radiographs in clinical practice: a systematic review. Clin Radiol (2006) 0.90
Quantification of circulating DNA: in the preparation lies the rub. Clin Chem (2001) 0.90
Filling-in percepts produced by luminance modulation. Vision Res (1996) 0.90
Genes controlling spread of breast cancer to lung "gang of 4". Exp Oncol (2008) 0.90
Levels of circulating cell-free serum DNA in benign and malignant breast lesions. Int J Biol Markers (2007) 0.90
Improved prenatal detection of a fetal point mutation for achondroplasia by the use of size-fractionated circulatory DNA in maternal plasma--case report. Prenat Diagn (2004) 0.89
Highly accurate analysis of heterozygous loci bysingle cell PCR. Nucleic Acids Res (1998) 0.89