Published in Bioessays on July 01, 1995
The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. EMBO J (1998) 7.68
The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol (1998) 4.63
AAA proteins. Lords of the ring. J Cell Biol (2000) 3.89
ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking. Mol Biol Cell (2000) 2.92
Degradation of carboxy-terminal-tagged cytoplasmic proteins by the Escherichia coli protease HflB (FtsH). Genes Dev (1998) 2.87
Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1. EMBO J (1996) 2.47
Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport. J Clin Invest (2004) 2.30
Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function. PLoS Biol (2004) 2.10
Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast. EMBO J (1998) 2.06
HslV-HslU: A novel ATP-dependent protease complex in Escherichia coli related to the eukaryotic proteasome. Proc Natl Acad Sci U S A (1996) 1.94
Science in motion: common molecular pathological themes emerge in the hereditary spastic paraplegias. J Med Genet (2003) 1.92
A protease complex in the Escherichia coli plasma membrane: HflKC (HflA) forms a complex with FtsH (HflB), regulating its proteolytic activity against SecY. EMBO J (1996) 1.91
Hereditary spastic paraparesis: a review of new developments. J Neurol Neurosurg Psychiatry (2000) 1.87
Sequence analysis of the AAA protein family. Protein Sci (1997) 1.75
Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation. Hum Mol Genet (2011) 1.72
Genome analysis and genome-wide proteomics of Thermococcus gammatolerans, the most radioresistant organism known amongst the Archaea. Genome Biol (2009) 1.69
The regulatory complex of Drosophila melanogaster 26S proteasomes. Subunit composition and localization of a deubiquitylating enzyme. J Cell Biol (2000) 1.66
Chaperone rings in protein folding and degradation. Proc Natl Acad Sci U S A (1999) 1.66
The peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptor. EMBO J (1996) 1.62
ZFYVE27 (SPG33), a novel spastin-binding protein, is mutated in hereditary spastic paraplegia. Am J Hum Genet (2006) 1.59
Katanin is responsible for the M-phase microtubule-severing activity in Xenopus eggs. Mol Biol Cell (1998) 1.54
Reduced levels of chloroplast FtsH protein in tobacco mosaic virus-infected tobacco leaves accelerate the hypersensitive reaction. Plant Cell (2000) 1.48
An Arabidopsis indole-3-butyric acid-response mutant defective in PEROXIN6, an apparent ATPase implicated in peroxisomal function. Proc Natl Acad Sci U S A (2004) 1.48
gamma-Secretase substrate selectivity can be modulated directly via interaction with a nucleotide-binding site. J Biol Chem (2005) 1.45
VCP associated inclusion body myopathy and paget disease of bone knock-in mouse model exhibits tissue pathology typical of human disease. PLoS One (2010) 1.34
Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1. Mol Biol Cell (1997) 1.32
Host regulation of lysogenic decision in bacteriophage lambda: transmembrane modulation of FtsH (HflB), the cII degrading protease, by HflKC (HflA). Proc Natl Acad Sci U S A (1997) 1.31
Amino-terminal sequences of sigmaN (sigma54) inhibit RNA polymerase isomerization. Genes Dev (1999) 1.31
Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family. Nucleic Acids Res (1998) 1.27
Dislocation of membrane proteins in FtsH-mediated proteolysis. EMBO J (1999) 1.24
SpoVM, a small protein essential to development in Bacillus subtilis, interacts with the ATP-dependent protease FtsH. J Bacteriol (1997) 1.22
Expansion of mutation spectrum, determination of mutation cluster regions and predictive structural classification of SPAST mutations in hereditary spastic paraplegia. Eur J Hum Genet (2008) 1.20
A nonproteolytic function of the proteasome is required for the dissociation of Cdc2 and cyclin B at the end of M phase. Genes Dev (2000) 1.19
Genetic and molecular characterization of the caenorhabditis elegans gene, mel-26, a postmeiotic negative regulator of mei-1, a meiotic-specific spindle component. Genetics (1998) 1.19
Identification of TER94, an AAA ATPase protein, as a Bam-dependent component of the Drosophila fusome. Mol Biol Cell (1999) 1.18
DNA damage modulates nucleolar interaction of the Werner protein with the AAA ATPase p97/VCP. Mol Biol Cell (2003) 1.17
The HflB protease of Escherichia coli degrades its inhibitor lambda cIII. J Bacteriol (1997) 1.16
Spastin, the most commonly mutated protein in hereditary spastic paraplegia interacts with Reticulon 1 an endoplasmic reticulum protein. Neurogenetics (2006) 1.15
The maize regulatory gene B-Peru contains a DNA rearrangement that specifies tissue-specific expression through both positive and negative promoter elements. Genetics (1998) 1.15
SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation. Mol Biol Cell (2003) 1.13
CDNA cloning of p112, the largest regulatory subunit of the human 26s proteasome, and functional analysis of its yeast homologue, sen3p. Mol Biol Cell (1996) 1.12
Proteolysis of bacteriophage lambda CII by Escherichia coli FtsH (HflB). J Bacteriol (2000) 1.12
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model. BMC Bioinformatics (2004) 1.12
Human PEX1 cloned by functional complementation on a CHO cell mutant is responsible for peroxisome-deficient Zellweger syndrome of complementation group I. Proc Natl Acad Sci U S A (1998) 1.11
The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor. Nucleic Acids Res (1997) 1.07
Suppression of ftsH mutant phenotypes by overproduction of molecular chaperones. J Bacteriol (1996) 1.03
cDNA isolation, characterization, and protein intracellular localization of a katanin-like p60 subunit from Arabidopsis thaliana. Protoplasma (2001) 0.99
The ATP-dependent PIM1 protease is required for the expression of intron-containing genes in mitochondria. Genes Dev (1998) 0.96
Sequencing, expression, and genetic characterization of the Helicobacter pylori ftsH gene encoding a protein homologous to members of a novel putative ATPase family. J Bacteriol (1996) 0.96
ATP-binding sites in brain p97/VCP (valosin-containing protein), a multifunctional AAA ATPase. Biochem J (2003) 0.93
The McrBC restriction endonuclease assembles into a ring structure in the presence of G nucleotides. EMBO J (2001) 0.93
Dynamic flexibility of the ATPase p97 is important for its interprotomer motion transmission. Proc Natl Acad Sci U S A (2012) 0.93
Large nucleotide-dependent movement of the N-terminal domain of the ClpX chaperone. EMBO J (2006) 0.92
Formation and turnover of NSF- and SNAP-containing "fusion" complexes occur on undocked, clathrin-coated vesicle-derived membranes. Mol Biol Cell (1998) 0.90
Structure of RavA MoxR AAA+ protein reveals the design principles of a molecular cage modulating the inducible lysine decarboxylase activity. Proc Natl Acad Sci U S A (2010) 0.89
The ftsH gene of the wine bacterium Oenococcus oeni is involved in protection against environmental stress. Appl Environ Microbiol (2003) 0.89
The absence of FtsH metalloprotease activity causes overexpression of the sigmaW-controlled pbpE gene, resulting in filamentous growth of Bacillus subtilis. J Bacteriol (2003) 0.88
Untethering the nuclear envelope and cytoskeleton: biologically distinct dystonias arising from a common cellular dysfunction. Int J Cell Biol (2012) 0.87
A screen for dominant negative mutants of SEC18 reveals a role for the AAA protein consensus sequence in ATP hydrolysis. Mol Biol Cell (2000) 0.84
Subunit Interactions and cooperativity in the microtubule-severing AAA ATPase spastin. J Biol Chem (2012) 0.82
A systematic classification of Plasmodium falciparum P-loop NTPases: structural and functional correlation. Malar J (2009) 0.82
Computer simulation of assembly and co-operativity of hexameric AAA ATPases. PLoS One (2013) 0.79
Microtubule severing by katanin p60 AAA+ ATPase requires the C-terminal acidic tails of both α- and β-tubulins and basic amino acid residues in the AAA+ ring pore. J Biol Chem (2015) 0.78
Valosin-containing protein (VCP/p97) is capable of unfolding polyubiquitinated proteins through its ATPase domains. Biochem Biophys Res Commun (2015) 0.76
Shedding light on the expansion and diversification of the Cdc48 protein family during the rise of the eukaryotic cell. BMC Evol Biol (2016) 0.75
Autosomal dominant hereditary spastic paraplegia: report of a large Italian family with R581X spastin mutation. Neurol Sci (2007) 0.75
Global gene expression profiling in R155H knock-in murine model of VCP disease. Clin Transl Sci (2014) 0.75
The complete genome of the crenarchaeon Sulfolobus solfataricus P2. Proc Natl Acad Sci U S A (2001) 7.00
Reverse gyrase: a helicase-like domain and a type I topoisomerase in the same polypeptide. Proc Natl Acad Sci U S A (1993) 2.04
High positive supercoiling in vitro catalyzed by an ATP and polyethylene glycol-stimulated topoisomerase from Sulfolobus acidocaldarius. EMBO J (1985) 1.77
DNA topoisomerases from rat liver: physiological variations. Nucleic Acids Res (1983) 1.74
Fine organization of Bombyx mori fibroin heavy chain gene. Nucleic Acids Res (2000) 1.71
Reverse gyrase, a hallmark of the hyperthermophilic archaebacteria. J Bacteriol (1990) 1.44
The mechanism of type IA topoisomerases. Proc Natl Acad Sci U S A (2002) 1.43
Completing the sequence of the Sulfolobus solfataricus P2 genome. Extremophiles (1998) 1.39
Reverse gyrase of Sulfolobus: purification to homogeneity and characterization. Biochemistry (1988) 1.25
Reverse gyrase in thermophilic eubacteria. J Bacteriol (1991) 1.22
Reverse gyrase, the two domains intimately cooperate to promote positive supercoiling. J Biol Chem (2000) 1.17
A deoxyribonucleic acid unwinding protein isolated from regenerating rat liver. Physical and functional properties. J Biol Chem (1978) 1.11
The nature of the last universal ancestor and the root of the tree of life, still open questions. Biosystems (1992) 1.11
Reverse gyrase binding to DNA alters the double helix structure and produces single-strand cleavage in the absence of ATP. EMBO J (1989) 1.08
Reverse gyrase from hyperthermophiles: probable transfer of a thermoadaptation trait from archaea to bacteria. Trends Genet (2000) 1.07
DNA topoisomerase activities in concanavalin A-stimulated lymphocytes. FEBS Lett (1984) 1.05
Identification of a single-stranded DNA binding protein from rat liver with high mobility group protein 1. J Biol Chem (1982) 1.01
Purification and characterization of reverse gyrase from Sulfolobus shibatae. Its proteolytic product appears as an ATP-independent topoisomerase. J Biol Chem (1994) 1.00
Thermophilic topoisomerase I on a single DNA molecule. J Mol Biol (2003) 0.98
Effect of histone H1, poly(ethyleneglycol) and DNA concentration on intermolecular and intramolecular ligation by T4 DNA ligase. Eur J Biochem (1988) 0.96
SAV, an archaebacterial gene with extensive homology to a family of highly conserved eukaryotic ATPases. J Mol Biol (1994) 0.96
Reverse gyrase gene from Sulfolobus shibatae B12: gene structure, transcription unit and comparative sequence analysis of the two domains. Nucleic Acids Res (1996) 0.94
Gene content and organization of a 281-kbp contig from the genome of the extremely thermophilic archaeon, Sulfolobus solfataricus P2. Genome (2000) 0.93
Analysis of DNA cleavage by reverse gyrase from Sulfolobus shibatae B12. Eur J Biochem (1999) 0.93
Hyperthermophilic topoisomerase I from Thermotoga maritima. A very efficient enzyme that functions independently of zinc binding. J Biol Chem (2001) 0.92
Single-strand deoxyribonucleic acid binding protein from rat liver changes the helical structure of deoxyribonucleic acid. Biochemistry (1981) 0.92
Speculations on the origin of life and thermophily: review of available information on reverse gyrase suggests that hyperthermophilic procaryotes are not so primitive. Orig Life Evol Biosph (1995) 0.91
A BAC library and paired-PCR approach to mapping and completing the genome sequence of Sulfolobus solfataricus P2. DNA Seq (2000) 0.90
The rep protein of Escherichia coli: interaction with DNA and other proteins. Cold Spring Harb Symp Quant Biol (1979) 0.90
ATP-dependent DNA topoisomerase from the archaebacterium Sulfolobus acidocaldarius. Relaxation of supercoiled DNA at high temperature. J Mol Biol (1984) 0.90
c-myc and c-fos gene regulation during mouse liver regeneration. Oncogene (1989) 0.88
Single-strand DNA binding protein from rat liver: interactions with supercoiled DNA. Nucleic Acids Res (1980) 0.87
[Vibrio cholera precipitating antigens. Their relation to agglutinant and immunofluorescent antigens]. Bull Soc Pathol Exot Filiales (1972) 0.87
Stimulation of rat liver alpha- and beta-type DNA polymerases by an homologous DNA-unwinding protein. FEBS Lett (1977) 0.87
Rat liver DNA binding proteins: physiological variations. FEBS Lett (1979) 0.86
Gene expression in regenerating liver in relation to cell proliferation and stress. Eur J Biochem (1989) 0.86
Reverse gyrases from bacteria and archaea. Methods Enzymol (2001) 0.83
A rapid technique to separate DNA polymerase-alpha and -beta activity from a cytosol extract. Anal Biochem (1978) 0.83
Cloning and sequencing of the gene coding for topoisomerase I from the extremely thermophilic eubacterium, Thermotoga maritima. Biochim Biophys Acta (1995) 0.82
In vivo topoisomerase II cleavage sites in the ribosomal DNA of Physarum polycephalum. Biochemistry (1996) 0.80
The mapping of DNA topoisomerase sites in vivo: a tool to enlight the functions of topoisomerases. Biochimie (1998) 0.80
Topoisomerase inhibitors induce irreversible fragmentation of replicated DNA in concanavalin A stimulated splenocytes. Biochemistry (1988) 0.79
Reverse gyrase from the hyperthermophilic bacterium Thermotoga maritima: properties and gene structure. J Bacteriol (1998) 0.79
Phylogeny of hemoglobins: the complete amino acid sequence of an alpha-chain of viper (Vipera aspis) hemoglobin. FEBS Lett (1974) 0.78
[Inflammatory rheumatisms and paraproteins excepting myeloma and Waldenström's disease. Study of 18 personal cases of this association]. Sem Hop (1969) 0.78
ATP-independent DNA topoisomerase from Fervidobacterium islandicum. Biochim Biophys Acta (1993) 0.76
DNA topoisomerase II sites in the histone H4 gene during the highly synchronous cell cycle of Physarum polycephalum. Nucleic Acids Res (1998) 0.76
The oxygen dissociation curve of viper (Vipera aspis) hemoglobin: functional similarity with human hemoglobin Portland. FEBS Lett (1975) 0.76
Inhibition of DNA synthesis and DNA fragmentation in stimulated splenocytes by the concerted action of topoisomerase I and II poisons. Biochem Pharmacol (1993) 0.76
Molecular biology of liver regeneration. Biochimie (1986) 0.75
Molecular cloning of mRNA sequences transiently induced during rat liver regeneration. Exp Cell Res (1987) 0.75
Comparison of biochemical properties of DNA-topoisomerase I from normal and regenerating liver. Eur J Biochem (1992) 0.75
Phylogeny of hemoglobins: amino acid sequence of residues 35 to 92 of a viper (Vipera aspis) hemoglobin alpha-chain. FEBS Lett (1974) 0.75
Regenerating rat liver topoisomerase II: purification of the enzyme and catenation of DNA rings. Adv Exp Med Biol (1984) 0.75
Proteins that shape DNA. Biochimie (1982) 0.75