PubRank

S P Lees-Miller

Author PubWeight™ 53.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell 1995 4.64
2 ATM associates with and phosphorylates p53: mapping the region of interaction. Nat Genet 1998 3.66
3 Herpes simplex virus type 1 immediate-early protein vmw110 induces the proteasome-dependent degradation of the catalytic subunit of DNA-dependent protein kinase. J Virol 1999 2.93
4 The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit. J Biol Chem 1996 2.92
5 Utilization of oriented peptide libraries to identify substrate motifs selected by ATM. J Biol Chem 2000 2.42
6 Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 2000 2.21
7 The nuclear serine/threonine protein kinase DNA-PK. Crit Rev Eukaryot Gene Expr 1992 2.05
8 DNA-dependent protein kinase catalytic subunit: a target for an ICE-like protease in apoptosis. EMBO J 1996 1.97
9 Protein phosphatases regulate DNA-dependent protein kinase activity. J Biol Chem 2001 1.89
10 Purification and characterization of the double-stranded DNA-activated protein kinase, DNA-PK, from human placenta. Biochem Cell Biol 1996 1.75
11 DNA-dependent protein kinase acts upstream of p53 in response to DNA damage. Nature 1998 1.68
12 Mutation of the serine 15 phosphorylation site of human p53 reduces the ability of p53 to inhibit cell cycle progression. Oncogene 1993 1.63
13 Accurate in vitro end joining of a DNA double strand break with partially cohesive 3'-overhangs and 3'-phosphoglycolate termini: effect of Ku on repair fidelity. J Biol Chem 2001 1.57
14 Tra1p is a component of the yeast Ada.Spt transcriptional regulatory complexes. J Biol Chem 1998 1.55
15 Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis. Mol Cell Biol 1998 1.40
16 DNA-dependent protein kinase phosphorylation sites in Ku 70/80 heterodimer. Biochemistry 1999 1.38
17 DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45. J Biol Chem 1998 1.32
18 Relative affinities of poly(ADP-ribose) polymerase and DNA-dependent protein kinase for DNA strand interruptions. Biochim Biophys Acta 1999 1.27
19 Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine. J Biol Chem 2001 1.27
20 Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase. J Biol Chem 2000 1.24
21 Lack of correlation between DNA-dependent protein kinase activity and tumor cell radiosensitivity. Cancer Res 1995 1.10
22 The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner. J Biol Chem 2000 1.07
23 Lack of correlation between ATM protein expression and tumour cell radiosensitivity. Int J Radiat Biol 1998 1.03
24 The human DNA-activated protein kinase phosphorylates simian virus 40 T antigen at amino- and carboxy-terminal sites. J Virol 1991 1.02
25 The viral tropism of two distinct oncolytic viruses, reovirus and myxoma virus, is modulated by cellular tumor suppressor gene status. Oncogene 2010 0.98
26 Phosphorylation at Ser-15 and Ser-392 in mutant p53 molecules from human tumors is altered compared to wild-type p53. Proc Natl Acad Sci U S A 1993 0.97
27 The carboxyl-terminal transactivation domain of human serum response factor contains DNA-activated protein kinase phosphorylation sites. J Biol Chem 1993 0.90
28 Cell cycle checkpoints and DNA repair in Nijmegen breakage syndrome. Clin Immunol Immunopathol 1997 0.89
29 Interleukin-1 beta-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing. J Exp Med 1996 0.86
30 Interaction of DNA-dependent protein kinase and poly(ADP-ribose) polymerase with radiation-induced DNA strand breaks. Radiat Res 1997 0.85
31 Detection of DNA-dependent protein kinase in extracts from human and rodent cells. Methods Mol Biol 2000 0.84
32 Dimerization and DNA binding alter phosphorylation of Fos and Jun. Proc Natl Acad Sci U S A 1993 0.84
33 Protein-DNA complexes containing DNA-dependent protein kinase in crude extracts from human and rodent cells. Radiat Res 1999 0.78
34 Examination of surface-bound Ku-DNA complexes in an aqueous environment using MAC mode atomic force microscopy. Biosens Bioelectron 2004 0.77
35 Resistance to etoposide-induced apoptosis in a Burkitt's lymphoma cell line. Int J Cancer 1998 0.75