Published in Cancer Res on May 01, 1993
Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff. Mol Cell Biol (2000) 2.41
Repair of topoisomerase I-mediated DNA damage. Prog Nucleic Acid Res Mol Biol (2006) 2.16
Processing of topoisomerase I cleavable complexes into DNA damage by transcription. Nucleic Acids Res (1997) 1.63
Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity. J Cell Biol (1996) 1.44
Transcription-dependent degradation of topoisomerase I-DNA covalent complexes. Mol Cell Biol (2003) 1.43
Genome-wide transcriptional effects of the anti-cancer agent camptothecin. PLoS One (2013) 1.00
Topoisomerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells. Nucleic Acids Res (1996) 0.95
Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation. EMBO J (2015) 0.81
Slx8 removes Pli1-dependent protein-SUMO conjugates including SUMOylated topoisomerase I to promote genome stability. PLoS One (2013) 0.77
Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies. Biomolecules (2017) 0.75
Mammalian cell fusion: studies on the regulation of DNA synthesis and mitosis. Nature (1970) 5.90
The neurological manifestations of systemic lupus erythematosus. Medicine (Baltimore) (1968) 4.40
Mammalian cell fusion: induction of premature chromosome condensation in interphase nuclei. Nature (1970) 4.21
Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen. Cancer Res (2001) 4.12
A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy. Cancer Res (2001) 3.37
Differential diagnosis of suspected multiple sclerosis: a consensus approach. Mult Scler (2008) 3.28
Isolation of virus related to SV40 from patients with progressive multifocal leukoencephalopathy. N Engl J Med (1972) 3.09
Age-dependent resistance to viral encephalitis: studies of infections due to Sindbis virus in mice. J Infect Dis (1972) 2.56
Pathogenesis of viral infections of the nervous system. N Engl J Med (1968) 2.48
A topoisomerase II-dependent G2 cycle checkpoint in mammalian cells/. Nature (1994) 2.35
Role of the immune response in recovery from Sindbis virus encephalitis in mice. J Immunol (1977) 2.32
Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry. Ann Neurol (1996) 2.22
Demented and nondemented patients with AIDS differ in brain-derived human immunodeficiency virus type 1 envelope sequences. J Virol (1994) 2.21
Complementation analysis on virus-fused Chinese hamster cells with nutritional markers. Science (1969) 2.12
Etiology of progressive multifocal leukoencephalopathy. Identification of papovavirus. N Engl J Med (1973) 1.90
Viral infections and demyelinating diseases. N Engl J Med (1973) 1.84
Hydrocephalus following viral infection: the pathology of aqueductal stenosis developing after experimental mumps virus infection. J Neuropathol Exp Neurol (1968) 1.75
Japanese encephalitis: immunocytochemical studies of viral antigen and inflammatory cells in fatal cases. Ann Neurol (1985) 1.73
Experimental rabies. Studies of cellular vulnerability and pathogenesis using fluorescent antibody staining. J Neuropathol Exp Neurol (1965) 1.72
Hydrocephalus as a sequela of experimental myxovirus infections. Exp Mol Pathol (1969) 1.68
Pathogenesis of human poliovirus infection in mice. I. Clinical and pathological studies. J Neuropathol Exp Neurol (1980) 1.68
A postprophase topoisomerase II-dependent chromatid core separation step in the formation of metaphase chromosomes. J Cell Biol (1995) 1.65
The pathogenesis of spinal cord involvement in the encephalomyelitis of mice caused by neuroadapted Sindbis virus infection. Lab Invest (1987) 1.63
Nucleo-cytoplasmic interactions in the acheivement of nuclear synchrony in DNA synthesis and mitosis in multinucleate cells. Biol Rev Camb Philos Soc (1971) 1.61
Serotypes and subtypes of Neisseria meningitidis serogroup B strains associated with meningococcal disease in Canada, 1977-1989. Can J Microbiol (1991) 1.60
Acute measles in patients with and without neurological involvement: distribution of measles virus antigen and RNA. J Infect Dis (1988) 1.59
Physiological characterization of heat-defective (temperature-sensitive) poliovirus mutants: preliminary classification. Virology (1966) 1.56
Neuronal death induced by brain-derived human immunodeficiency virus type 1 envelope genes differs between demented and nondemented AIDS patients. J Virol (1998) 1.52
Age dependence of viral expression: comparative pathogenesis of two rodent-adapted strains of measles virus in mice. Infect Immun (1974) 1.51
Measles encephalomyelitis--clinical and immunologic studies. N Engl J Med (1984) 1.50
Spongiform polioencephalomyelopathy caused by a murine retrovirus. I. Pathogenesis of infection in newborn mice. Lab Invest (1980) 1.48
Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA. Nucleic Acids Res (1991) 1.47
A class of amphipathic proteins associated with lipid storage bodies in plants. Possible similarities with animal serum apolipoproteins. Biochim Biophys Acta (1991) 1.46
Papovavirus of JC type in progressive multifocal leukoencephalopathy. Rapid identification and subsequent isolation. Arch Neurol (1973) 1.43
Enzymatic reduction of tartrazine by Proteus vulgaris from rats. Food Cosmet Toxicol (1967) 1.40
Specificity of the inflammatory response in viral encephalitis. I. Adoptive immunization of immunosuppressed mice infected with Sindbis virus. J Exp Med (1972) 1.39
Topoisomerase II inhibition prevents anaphase chromatid segregation in mammalian cells independently of the generation of DNA strand breaks. J Cell Sci (1993) 1.38
The pathogenesis of acute viral encephalitis and postinfectious encephalomyelitis. J Infect Dis (1987) 1.37
Pathogenesis of human poliovirus infection in mice. II. Age-dependency of paralysis. J Neuropathol Exp Neurol (1980) 1.37
The metabolism and excretion of curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) in the rat. Xenobiotica (1978) 1.37
An explanation for the localization of herpes simplex encephalitis? Ann Neurol (1979) 1.35
Mammalian cell fusion. 3. A HeLa cell inducer of premature chromosome condensation active in cells from a variety of animal species. J Cell Physiol (1970) 1.34
Immune activation in measles. N Engl J Med (1989) 1.33
Virions from progressive multifocal leukoencephalopathy: rapid serological identification by electron microscopy. Science (1972) 1.33
Spongiform polioencephalomyelopathy caused by a murine retrovirus. II. Ultrastructural localization of virus replication and spongiform changes in the central nervous system. Neuropathol Appl Neurobiol (1982) 1.33
Murine neurotropic retrovirus spongiform polioencephalomyelopathy: acceleration of disease by virus inoculum concentration. Infect Immun (1979) 1.31
The synthesis and structure of visna virus DNA. Virology (1979) 1.30
Distinct HIV-1 env sequences are associated with neurotropism and neurovirulence. Curr Top Microbiol Immunol (1995) 1.29
Experimental viral-induced congenital encephalopathies. I. Pathology of hydranencephaly and porencephaly caused by bluetongue vaccine virus. Lab Invest (1971) 1.28
Further studies of a simian virus 40-like virus isolated from human brain. J Virol (1972) 1.28
Herpes simplex virus infections of the nervous system. Problems in laboratory diagnosis. Arch Neurol (1968) 1.27
Detection of polyoma virus DNA in PML-brain tissue by (in situ) hybridization. J Gen Virol (1979) 1.27
Experimental viral infections of the inner ear. I. Acute infections of the newborn hamster labyrinth. Lab Invest (1976) 1.26
Thyrotoxic periodic paralysis. South Med J (2000) 1.25
Virus-induced hydrocephalus: development of aqueductal stenosis in hamsters after mumps infection. Science (1967) 1.24
Inhibitors of DNA topoisomerase II prevent chromatid separation in mammalian cells but do not prevent exit from mitosis. Proc Natl Acad Sci U S A (1991) 1.23
Tumour dose response to the antivascular agent ZD6126 assessed by magnetic resonance imaging. Br J Cancer (2003) 1.23
Tumor necrosis factor-alpha inhibits expression of CTP:phosphocholine cytidylyltransferase. J Biol Chem (2000) 1.21
Experimental viral-induced congenital encephalopathies. II. The pathogenesis of bluetongue vaccine virus infection in fetal lambs. Lab Invest (1971) 1.21
Immune activation during measles: interferon-gamma and neopterin in plasma and cerebrospinal fluid in complicated and uncomplicated disease. J Infect Dis (1990) 1.20
Development of antibody to measles virus polypeptides during complicated and uncomplicated measles virus infections. J Virol (1984) 1.20
Cellular immune responses during complicated and uncomplicated measles virus infections of man. Clin Immunol Immunopathol (1984) 1.18
Measurement of radiation-induced DNA double-strand breaks by pulsed-field gel electrophoresis. Radiat Res (1990) 1.18
Cytokine production in vitro and the lymphoproliferative defect of natural measles virus infection. Clin Immunol Immunopathol (1991) 1.18
Cellular immune response to viral infection: in vitro studies of lymphocytes from mice infected with Sindbis virus. Cell Immunol (1973) 1.17
Effect of running intensity on intestinal permeability. J Appl Physiol (1985) (1997) 1.15
Premature chromosome condensation: a mechanism for the elimination of chromosomes in virus-fused cells. J Cell Sci (1972) 1.15
The excretion of [14C] butylated hydroxytoluene in the rat. J Pharm Pharmacol (1967) 1.14
CHO mutant UV61 removes (6-4) photoproducts but not cyclobutane dimers. Mutagenesis (1989) 1.14
Lack of correlation between residual radiation-induced DNA damage, in keratinocytes assayed directly from skin, and late radiotherapy reactions in breast cancer patients. Int J Radiat Oncol Biol Phys (1999) 1.13
Myelin basic protein as an encephalitogen in encephalomyelitis and polyneuritis following rabies vaccination. N Engl J Med (1987) 1.12
Experimental viral polymyositis: age dependency and immune responses to Ross River virus infection in mice. Neurology (1981) 1.10
Late progression of poliomyelitis paralysis: discussion of pathogenesis. Rev Infect Dis (1984) 1.08
Cells from ERCC1-deficient mice show increased genome instability and a reduced frequency of S-phase-dependent illegitimate chromosome exchange but a normal frequency of homologous recombination. J Cell Sci (1998) 1.07
Bacterial azo reduction: a metabolic reaction in mammals. Nature (1968) 1.07
Effect of high-dose dexamethasone on the outcome of acute encephalitis due to Japanese encephalitis virus. J Infect Dis (1992) 1.07
Tissue-specific HSP70 response in animals undergoing heat stress. Am J Physiol (1995) 1.07
The inhibition of repair in UV irradiated human cells. Mutat Res (1977) 1.05
Comparative studies of five strains of mumps virus in vitro and in neonatal hamsters: evaluation of growth, cytopathogenicity, and neurovirulence. J Med Virol (1980) 1.05
Subacute sclerosing panencephalitis. J Infect Dis (1970) 1.05
Inhibiting vascular endothelial growth factor receptor-2 signaling reduces tumor burden in the ApcMin/+ mouse model of early intestinal cancer. Carcinogenesis (2006) 1.04
Development of the Utah artificial arm. IEEE Trans Biomed Eng (1982) 1.03
Human immunodeficiency virus and the brain. Annu Rev Neurosci (1996) 1.02
Effects of viral infection on nervous system development. I. Pathogenesis of bluetongue virus infection in mice. Am J Pathol (1972) 1.02
Novobiocin inhibition of DNA excision repair may occur through effects on mitochondrial structure and ATP metabolism, not on repair topoisomerases. Carcinogenesis (1985) 1.02
The pathogenesis of rat virus infections in the newborn hamster. Lab Invest (1972) 1.01
Virologic studies of multiple sclerosis and other chronic and relapsing neurological diseases. Prog Med Virol (1974) 1.01
Giemsa banding in prematurely condensed chromosomes obtained by cell fusion. Nat New Biol (1973) 1.01
Granular ependymitis. Occurrence in myxovirus infected rodents and prevalence in man. Am J Pathol (1972) 1.01
Yes, brain biopsy should be a prerequisite for herpes simplex encephalitis treatment. Arch Neurol (1987) 1.00
The possible viral etiology of multiple sclerosis. Adv Neurol (1975) 1.00
Changes in the organization of chromosomes during the cell cycle: response to ultraviolet light. J Cell Sci (1975) 1.00
Does competition enhance or inhibit motor performance: a meta-analysis. Psychol Bull (1999) 1.00
Androgen receptor regulation of G1 cyclin and cyclin-dependent kinase function in the CWR22 human prostate cancer xenograft. J Androl (2001) 1.00
SYBR Green I staining of pulsed field agarose gels is a sensitive and inexpensive way of quantitating DNA double-strand breaks in mammalian cells. Nucleic Acids Res (1997) 1.00
Initial rates of DNA incision in UV-irradiated human cells: differences between normal, xeroderma pigmentosum and tumour cells. Mutat Res (1982) 1.00
Inhibitors of repair DNA synthesis. Nucleic Acids Res (1982) 0.99
Nitric oxide synthase inhibitors decrease coronary sinus-free radical concentration and ameliorate myocardial stunning in an ischemia-reperfusion model. J Am Coll Cardiol (2001) 0.99
Premitotic chromosome individualization in mammalian cells depends on topoisomerase II activity. Chromosoma (2000) 0.98