Glutamate uptake from the synaptic cleft does not shape the decay of the non-NMDA component of the synaptic current.

PubWeight™: 1.22‹?› | Rank: Top 10%

🔗 View Article (PMID 7691104)

Published in Neuron on September 01, 1993

Authors

M Sarantis1, L Ballerini, B Miller, R A Silver, M Edwards, D Attwell

Author Affiliations

1: Department of Physiology, University College London, England.

Articles citing this

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron (2009) 3.94

Pre- and postsynaptic glutamate receptors at a giant excitatory synapse in rat auditory brainstem slices. J Physiol (1995) 2.00

Independent sources of quantal variability at single glutamatergic synapses. J Neurosci (2003) 1.95

A Monte Carlo model reveals independent signaling at central glutamatergic synapses. Biophys J (2002) 1.93

The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects. Pflugers Arch (2003) 1.75

Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis? J Neurosci (2009) 1.57

Receptor actions of synaptically released glutamate: the role of transporters on the scale from nanometers to microns. Biophys J (2008) 1.56

Multivesicular release at Schaffer collateral-CA1 hippocampal synapses. J Neurosci (2006) 1.55

Currents evoked in Bergmann glial cells by parallel fibre stimulation in rat cerebellar slices. J Physiol (1997) 1.47

Glutamate transporter currents in bergmann glial cells follow the time course of extrasynaptic glutamate. Proc Natl Acad Sci U S A (1997) 1.41

Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex. Neurobiol Dis (2007) 1.37

Modeling the effect of glutamate diffusion and uptake on NMDA and non-NMDA receptor saturation. Biophys J (1995) 1.31

Glutamate transporter studies reveal the pruning of metabotropic glutamate receptors and absence of AMPA receptor desensitization at mature calyx of Held synapses. J Neurosci (2005) 1.25

Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signaling. Pharmacol Rev (2012) 1.21

Modulation of extracellular glutamate concentration in rat brain slices by cystine-glutamate exchange. J Physiol (1999) 1.18

The role of glial glutamate transporters in maintaining the independent operation of juvenile mouse cerebellar parallel fibre synapses. J Physiol (2003) 1.14

A computational model to investigate astrocytic glutamate uptake influence on synaptic transmission and neuronal spiking. Front Comput Neurosci (2012) 1.04

Diabetes-induced dysfunction of retinal Müller cells. Trans Am Ophthalmol Soc (2002) 1.03

Decreased glutamate transport enhances excitability in a rat model of cortical dysplasia. Neurobiol Dis (2008) 1.00

Extrasynaptic targeting of NMDA receptors following D1 dopamine receptor activation and cocaine self-administration. J Neurosci (2013) 0.85

Simulation of postsynaptic glutamate receptors reveals critical features of glutamatergic transmission. PLoS One (2011) 0.85

Specificity and actions of an arylaspartate inhibitor of glutamate transport at the Schaffer collateral-CA1 pyramidal cell synapse. PLoS One (2011) 0.78

Articles by these authors

(truncated to the top 100)

Parallel declines in pollinators and insect-pollinated plants in Britain and the Netherlands. Science (2006) 11.10

Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease. Arch Neurol (2001) 9.96

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ (2007) 7.74

Practice parameter: diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology (2001) 7.51

THE SEPARATION OF TYPES AMONG THE PNEUMOCOCCI HITHERTO CALLED GROUP IV AND THE DEVELOPMENT OF THERAPEUTIC ANTISERUMS FOR THESE TYPES. J Exp Med (1929) 5.24

Magnetodendrimers allow endosomal magnetic labeling and in vivo tracking of stem cells. Nat Biotechnol (2001) 4.54

School-based programs to reduce sexual risk behaviors: a review of effectiveness. Public Health Rep (1994) 4.50

The effects of frequent nocturnal home hemodialysis: the Frequent Hemodialysis Network Nocturnal Trial. Kidney Int (2011) 4.27

The release and uptake of excitatory amino acids. Trends Pharmacol Sci (1990) 3.80

Genetic and morphological analysis of a maize-teosinte F2 population: implications for the origin of maize. Proc Natl Acad Sci U S A (1990) 3.70

School-based screening for tuberculous infection. A cost-benefit analysis. JAMA (1995) 3.47

The steady state TTX-sensitive ("window") sodium current in cardiac Purkinje fibres. Pflugers Arch (1979) 3.34

Are amyotrophic lateral sclerosis patients cognitively normal? Neurology (2003) 3.21

Glutamate release in severe brain ischaemia is mainly by reversed uptake. Nature (2000) 2.78

High cerebrospinal fluid tau and low amyloid beta42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype. Arch Neurol (1998) 2.77

Breast cancer among black and white women in the 1980s. Changing patterns in the United States by race, age, and extent of disease. Cancer (1993) 2.70

Neurobehavioral effects of phenytoin prophylaxis of posttraumatic seizures. JAMA (1991) 2.64

Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease. Ann Neurol (1995) 2.62

GFAP and S100B are biomarkers of traumatic brain injury: an observational cohort study. Neurology (2010) 2.52

Stoichiometry of the glial glutamate transporter GLT-1 expressed inducibly in a Chinese hamster ovary cell line selected for low endogenous Na+-dependent glutamate uptake. J Neurosci (1998) 2.50

Classification of community hospitals by scope of service: four indexes. Health Serv Res (1972) 2.48

A Trojan Horse mechanism for the spread of visna virus in monocytes. Virology (1985) 2.47

Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia. J Clin Invest (1984) 2.43

2004 consensus statements on the management of ovarian cancer: final document of the 3rd International Gynecologic Cancer Intergroup Ovarian Cancer Consensus Conference (GCIG OCCC 2004). Ann Oncol (2005) 2.33

Early retinal damage in experimental diabetes: electroretinographical and morphological observations. Exp Eye Res (2002) 2.32

Haptoglobin phenotype and diabetic nephropathy. Diabetologia (2001) 2.27

Airway smooth muscle, tidal stretches, and dynamically determined contractile states. Am J Respir Crit Care Med (1997) 2.26

Systematic review and meta-analysis of the effect of North American working hours restrictions on mortality and morbidity in surgical patients. Br J Surg (2012) 2.21

Electrogenic glutamate uptake is a major current carrier in the membrane of axolotl retinal glial cells. Nature (1987) 2.18

Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Nature (2000) 2.16

Behaviour of the rod network in the tiger salamander retina mediated by membrane properties of individual rods. J Physiol (1980) 2.15

Deformation tensor morphometry of semantic dementia with quantitative validation. Neuroimage (2004) 2.14

Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17. Proc Natl Acad Sci U S A (1998) 2.13

The mechanism of lysis in phage T4-infected cells. Virology (1967) 2.12

Glutamate does not play a major role in controlling bone growth. J Bone Miner Res (2001) 2.12

Potentiation of NMDA receptor currents by arachidonic acid. Nature (1992) 2.10

Estimated conductance of glutamate receptor channels activated during EPSCs at the cerebellar mossy fiber-granule cell synapse. Neuron (1993) 2.08

Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine. Science (1996) 2.05

A comparative analysis of ADL questions in surveys of older people. J Gerontol B Psychol Sci Soc Sci (1997) 1.91

Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake. Nature (1990) 1.91

The role of retinal pigment epithelium in the involution of subretinal neovascularization. Invest Ophthalmol Vis Sci (1986) 1.90

Unveiling synaptic plasticity: a new graphical and analytical approach. Trends Neurosci (2000) 1.84

Purification and properties of a novel xyloglucan-specific endo-(1----4)-beta-D-glucanase from germinated nasturtium seeds (Tropaeolum majus L.). J Biol Chem (1986) 1.83

The morphology of human pronuclear embryos is positively related to blastocyst development and implantation. Hum Reprod (2000) 1.82

The glial cell glutamate uptake carrier countertransports pH-changing anions. Nature (1992) 1.80

Assessment of CSF levels of tau protein in mildly demented patients with Alzheimer's disease. Neurology (1997) 1.78

Expression of a synthetic gene for horseradish peroxidase C in Escherichia coli and folding and activation of the recombinant enzyme with Ca2+ and heme. J Biol Chem (1990) 1.68

Finasteride in the treatment of men with frontal male pattern hair loss. J Am Acad Dermatol (1999) 1.67

Voltage clamp and tracer flux data: effects of a restricted extra-cellular space. Q Rev Biophys (1979) 1.67

Prevalence and severity of lifetime physical and sexual victimization among incarcerated women. Int J Law Psychiatry (1999) 1.62

Glutamate spillover suppresses inhibition by activating presynaptic mGluRs. Nature (2000) 1.59

Kinetics of light-sensitive channels in vertebrate photoreceptors. Proc R Soc Lond B Biol Sci (1985) 1.59

Transvaginal sonography in the evaluation of normal early pregnancy: correlation with HCG level. AJR Am J Roentgenol (1989) 1.55

The levels of reliability and validity of the Waterlow pressure sore risk calculator. J Wound Care (1995) 1.54

Closure of the fenestration in the extracardiac Fontan with the Amplatzer duct occluder device. Catheter Cardiovasc Interv (2001) 1.54

Withdrawal of medical research council funding for intercalated BSc students. Lancet (1996) 1.52

Most germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a premature termination of the PATCHED protein, and no genotype-phenotype correlations are evident. Am J Hum Genet (1997) 1.50

Signal clipping by the rod output synapse. Nature (1987) 1.50

Health-care expenditures for tuberculosis in the United States. Arch Intern Med (1995) 1.48

Changes in the incidence of childhood autism and other autistic spectrum disorders in preschool children from two areas of the West Midlands, UK. Dev Med Child Neurol (2000) 1.48

Mutation analysis of the MEN1 gene in multiple endocrine neoplasia type 1, familial acromegaly and familial isolated hyperparathyroidism. J Clin Endocrinol Metab (1998) 1.46

Sleep-disordered breathing in stable methadone programme patients: a pilot study. Addiction (2001) 1.46

Causes and costs of hospitalization of tuberculosis patients in the United States. Int J Tuberc Lung Dis (2000) 1.45

Electrogenic uptake of glutamate and aspartate into glial cells isolated from the salamander (Ambystoma) retina. J Physiol (1991) 1.44

Pre- and postsynaptic determinants of EPSC waveform at cerebellar climbing fiber and parallel fiber to Purkinje cell synapses. J Neurosci (1995) 1.44

Fast removal of synaptic glutamate by postsynaptic transporters. Neuron (2000) 1.44

Seven days of erythromycin estolate is as effective as fourteen days for the treatment of Bordetella pertussis infections. Pediatrics (1997) 1.43

GABA spillover from single inhibitory axons suppresses low-frequency excitatory transmission at the cerebellar glomerulus. J Neurosci (2000) 1.43

The properties of single cones isolated from the tiger salamander retina. J Physiol (1982) 1.42

Electrogenic glutamate uptake in glial cells is activated by intracellular potassium. Nature (1988) 1.42

Decreased analyte transport through implanted membranes: differentiation of biofouling from tissue effects. J Biomed Mater Res (2001) 1.41

Triggering and execution of neuronal death in brain ischaemia: two phases of glutamate release by different mechanisms. Trends Neurosci (1994) 1.40

Recovery position. Br Dent J (1993) 1.39

Evaluation of the Damus-Kaye-Stansel operation in infancy. Ann Thorac Surg (1991) 1.39

CHILD syndrome: analysis of abnormal keratinization and ultrastructure. Pediatr Dermatol (1995) 1.38

A presynaptic action of glutamate at the cone output synapse. Nature (1988) 1.37

Constitutional p53 mutations associated with brain tumors in young adults. Cancer Genet Cytogenet (1995) 1.35

Anion conductance behavior of the glutamate uptake carrier in salamander retinal glial cells. J Neurosci (1996) 1.34

A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: new insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2). Neuroscience (2008) 1.34

The voltage clamp of multicellular preparations. Prog Biophys Mol Biol (1977) 1.33

Prevalence of tics in schoolchildren and association with placement in special education. Neurology (2001) 1.32

Transformation of murine melanocytes by basic fibroblast growth factor cDNA and oncogenes and selective suppression of the transformed phenotype in a reconstituted cutaneous environment. J Cell Biol (1989) 1.32

A sign-reversing pathway from rods to double and single cones in the retina of the tiger salamander. J Physiol (1983) 1.31

Development of friable embryogenic callus and embryogenic suspension culture systems in cassava (Manihot esculenta Crantz) Nat Biotechnol (1996) 1.30

Depressive symptomatology in middle-aged and older married couples: a dyadic analysis. J Gerontol B Psychol Sci Soc Sci (2001) 1.29

Competitive binding of vascular cell adhesion molecule-1 and the HepII/IIICS domain of fibronectin to the integrin alpha 4 beta 1. J Biol Chem (1994) 1.29

Neuropsychiatric aspects of multi-infarct dementia and dementia of the Alzheimer type. Arch Neurol (1987) 1.29

Serine/threonine protein phosphatase 5 (PP5) participates in the regulation of glucocorticoid receptor nucleocytoplasmic shuttling. BMC Cell Biol (2001) 1.28

THAP1 mutations (DYT6) are an additional cause of early-onset dystonia. Neurology (2010) 1.28

Elevation of microtubule-associated protein tau in the cerebrospinal fluid of patients with Alzheimer's disease. Neurology (1995) 1.27

Multiple GF-1 binding sites flank the erythroid specific transcription unit of the human carbonic anhydrase I gene. FEBS Lett (1989) 1.26

Recurrence of maltreatment: an application of the National Child Abuse and Neglect Data System (NCANDS). Child Abuse Negl (1999) 1.25

Endfeet of retinal glial cells have higher densities of ion channels that mediate K+ buffering. Nature (1987) 1.25

Four novel mutations in the RPE65 gene in patients with Leber congenital amaurosis. Hum Mutat (2001) 1.24

Neurotransmitter receptors in the life and death of oligodendrocytes. Neuroscience (2006) 1.24

Midlife cardiovascular risk factors, ApoE, and cognitive decline in elderly male twins. Neurology (1998) 1.24

The behavioral spectrum of tic disorders: a community-based study. Neurology (2002) 1.23

Neurofibromatosis types 1 and 2: cranial MR findings. Radiology (1989) 1.22

A quantitative analysis of interactions between photoreceptors in the salamander (Ambystoma) retina. J Physiol (1984) 1.21

Antigenic analysis of gonococcal pili using monoclonal antibodies. J Exp Med (1984) 1.21