Published in Cancer Genet Cytogenet on July 15, 1995
Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Natl Acad Sci U S A (2007) 15.88
Li-Fraumeni syndrome--a molecular and clinical review. Br J Cancer (1997) 2.14
Molecular epidemiology of primary brain tumors. Neurotherapeutics (2009) 1.22
Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis. Mol Cancer (2009) 1.19
A hypoxia-regulated adeno-associated virus vector for cancer-specific gene therapy. Neoplasia (2001) 1.13
p53 Gene repair with zinc finger nucleases optimised by yeast 1-hybrid and validated by Solexa sequencing. PLoS One (2011) 1.04
The intrinsic radioresistance of glioblastoma-derived cell lines is associated with a failure of p53 to induce p21(BAX) expression. Proc Natl Acad Sci U S A (1998) 1.00
Inherited predisposition to glioma. Neuro Oncol (2009) 0.99
Low-dose fractionated radiotherapy and concomitant chemotherapy in glioblastoma multiforme with poor prognosis: a feasibility study. Neuro Oncol (2011) 0.79
Induction and characterization of human glioma clones with different radiosensitivities. Neoplasia (1999) 0.79
Parallel declines in pollinators and insect-pollinated plants in Britain and the Netherlands. Science (2006) 11.10
A rapid method for detecting and mapping homology between heterologous DNAs. Evaluation of polyomavirus genomes. J Biol Chem (1979) 5.32
THE SEPARATION OF TYPES AMONG THE PNEUMOCOCCI HITHERTO CALLED GROUP IV AND THE DEVELOPMENT OF THERAPEUTIC ANTISERUMS FOR THESE TYPES. J Exp Med (1929) 5.24
Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation. Cell (1984) 5.05
Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta. Genes Dev (1995) 4.94
Molecular cloning of the Harvey sarcoma virus closed circular DNA intermediates: initial structural and biological characterization. J Virol (1979) 3.90
Beta 2-microglobulin expression in human embryonal neuroblastoma reflects its developmental regulation. Cancer Res (1990) 3.75
Genetic and morphological analysis of a maize-teosinte F2 population: implications for the origin of maize. Proc Natl Acad Sci U S A (1990) 3.70
Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma. Nature (1985) 3.50
Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins. Nature (2000) 3.36
Cloning of human papilloma virus genomic DNAs and analysis of homologous polynucleotide sequences. J Virol (1980) 3.34
Molecular cloning of polyoma virus DNA in Escherichia coli: lambda phage vector system. Science (1979) 3.17
GFAP and S100B are biomarkers of traumatic brain injury: an observational cohort study. Neurology (2010) 2.52
Classification of community hospitals by scope of service: four indexes. Health Serv Res (1972) 2.48
A Trojan Horse mechanism for the spread of visna virus in monocytes. Virology (1985) 2.47
The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein. Genes Dev (1994) 2.47
Characterization of polyoma viral DNA sequences in polyoma-induced hamster tumor cell lines. J Biol Chem (1980) 2.33
Chromosome translocation in peripheral neuroepithelioma. N Engl J Med (1984) 2.22
Systematic review and meta-analysis of the effect of North American working hours restrictions on mortality and morbidity in surgical patients. Br J Surg (2012) 2.21
Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine. Science (1996) 2.05
Cytogenetic characterization of selected small round cell tumors of childhood. Cancer Genet Cytogenet (1986) 2.04
Tyrosine phosphorylation within the amino-terminal domain of pp60c-src molecules associated with polyoma virus middle-sized tumor antigen. Proc Natl Acad Sci U S A (1985) 1.96
Expression of nitric oxide synthase in human central nervous system tumors. Cancer Res (1995) 1.92
Id proteins at the cross-road of development and cancer. Oncogene (2001) 1.90
Molecular markers of neuroendocrine development and evidence of environmental regulation. Proc Natl Acad Sci U S A (1987) 1.84
Purification and properties of a novel xyloglucan-specific endo-(1----4)-beta-D-glucanase from germinated nasturtium seeds (Tropaeolum majus L.). J Biol Chem (1986) 1.83
Id2 specifically alters regulation of the cell cycle by tumor suppressor proteins. Mol Cell Biol (1996) 1.81
Molecular cloning of polyoma virus DNA in Escherichia coli: plasmid vector system. Science (1979) 1.74
Middle tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with pp60c-src. J Virol (1985) 1.71
Biological activity of polyoma viral DNA in mice and hamsters. J Virol (1979) 1.70
Expression of a synthetic gene for horseradish peroxidase C in Escherichia coli and folding and activation of the recombinant enzyme with Ca2+ and heme. J Biol Chem (1990) 1.68
Retrospective study of the correlation between the DNA repair protein alkyltransferase and survival of brain tumor patients treated with carmustine. Cancer Res (1996) 1.68
Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues. J Biol Chem (1986) 1.67
Intravenous recombinant interferon beta in patients with recurrent malignant gliomas: a phase I/II study. J Clin Oncol (1991) 1.60
Analysis of complex relationships between age, p53, epidermal growth factor receptor, and survival in glioblastoma patients. Cancer Res (2001) 1.59
Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation. J Biol Chem (1996) 1.58
Inhibition of apoptosis by the retinoblastoma gene product. EMBO J (1995) 1.58
Transvaginal sonography in the evaluation of normal early pregnancy: correlation with HCG level. AJR Am J Roentgenol (1989) 1.55
The levels of reliability and validity of the Waterlow pressure sore risk calculator. J Wound Care (1995) 1.54
A human Id-like helix-loop-helix protein expressed during early development. Proc Natl Acad Sci U S A (1992) 1.53
Increased pp60c-src tyrosyl kinase activity in human neuroblastomas is associated with amino-terminal tyrosine phosphorylation of the src gene product. Proc Natl Acad Sci U S A (1985) 1.52
Most germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a premature termination of the PATCHED protein, and no genotype-phenotype correlations are evident. Am J Hum Genet (1997) 1.50
Cloned human polyomavirus JC DNA can transform human amnion cells. J Virol (1980) 1.50
Isolation of amplified and overexpressed DNA sequences from adriamycin-resistant human breast cancer cells. Cancer Res (1987) 1.49
Changes in the incidence of childhood autism and other autistic spectrum disorders in preschool children from two areas of the West Midlands, UK. Dev Med Child Neurol (2000) 1.48
Immortalization of primary human keratinocytes by the helix-loop-helix protein, Id-1. Proc Natl Acad Sci U S A (1999) 1.47
Mutation analysis of the MEN1 gene in multiple endocrine neoplasia type 1, familial acromegaly and familial isolated hyperparathyroidism. J Clin Endocrinol Metab (1998) 1.46
Interrupting the early region of polyoma virus DNA enhances tumorigenicity. Proc Natl Acad Sci U S A (1979) 1.45
Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II. J Clin Invest (1989) 1.41
Recovery position. Br Dent J (1993) 1.39
CHILD syndrome: analysis of abnormal keratinization and ultrastructure. Pediatr Dermatol (1995) 1.38
ENC-1: a novel mammalian kelch-related gene specifically expressed in the nervous system encodes an actin-binding protein. J Neurosci (1997) 1.37
Health-related quality of life in patients treated with temozolomide versus procarbazine for recurrent glioblastoma multiforme. J Clin Oncol (2000) 1.35
Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F. Oncogene (1998) 1.34
Id-1 and Id-2 are overexpressed in pancreatic cancer and in dysplastic lesions in chronic pancreatitis. Am J Pathol (1999) 1.33
Transformation of murine melanocytes by basic fibroblast growth factor cDNA and oncogenes and selective suppression of the transformed phenotype in a reconstituted cutaneous environment. J Cell Biol (1989) 1.32
Carboplatin and vincristine for recurrent and newly diagnosed low-grade gliomas of childhood. J Clin Oncol (1993) 1.32
Development of friable embryogenic callus and embryogenic suspension culture systems in cassava (Manihot esculenta Crantz) Nat Biotechnol (1996) 1.30
Competitive binding of vascular cell adhesion molecule-1 and the HepII/IIICS domain of fibronectin to the integrin alpha 4 beta 1. J Biol Chem (1994) 1.29
THAP1 mutations (DYT6) are an additional cause of early-onset dystonia. Neurology (2010) 1.28
Id-2 regulates critical aspects of human cytotrophoblast differentiation, invasion and migration. Development (2000) 1.26
Multiple GF-1 binding sites flank the erythroid specific transcription unit of the human carbonic anhydrase I gene. FEBS Lett (1989) 1.26
Recurrence of maltreatment: an application of the National Child Abuse and Neglect Data System (NCANDS). Child Abuse Negl (1999) 1.25
Expression of neuroendocrine cell markers L-dopa decarboxylase, chromogranin A, and dense core granules in human tumors of endocrine and nonendocrine origin. Cancer Res (1988) 1.24
Glutamate uptake from the synaptic cleft does not shape the decay of the non-NMDA component of the synaptic current. Neuron (1993) 1.22
Neurofibromatosis types 1 and 2: cranial MR findings. Radiology (1989) 1.22
EGFR overexpression and radiation response in glioblastoma multiforme. Int J Radiat Oncol Biol Phys (2001) 1.21
Antigenic analysis of gonococcal pili using monoclonal antibodies. J Exp Med (1984) 1.21
Intestinal preconditioning is mediated by a transient increase in nitric oxide. Biochem Biophys Res Commun (1996) 1.21
Identification of inosine and hypoxanthine as endogenous inhibitors of [3H] diazepam binding in the central nervous system. Life Sci (1978) 1.20
Using next-generation sequencing for molecular reconstruction of past Arctic vegetation and climate. Mol Ecol Resour (2010) 1.20
A randomized controlled trial of a "buddy" systems to improve success at giving up smoking in general practice. Addiction (1998) 1.19
The function of visual search and memory in sequential looking tasks. Vision Res (1995) 1.19
Dilute concentrations of a psychiatric drug alter behavior of fish from natural populations. Science (2013) 1.18
Potency of 10 BCG vaccines as evaluated by their influence on the bacillemic phase of experimental airborne tuberculosis in guinea-pigs. J Biol Stand (1979) 1.18
Influence of metabolic conditions on light-induced absorbancy changes in Chromatium D. Biochim Biophys Acta (1965) 1.17
CDIP-58 can measure the impact of botulinum toxin treatment in cervical dystonia. Neurology (2006) 1.16
A multi-institutional retrospective study of intracranial ependymoma in children: identification of risk factors. J Pediatr Hematol Oncol (1999) 1.16
Comparison of constitutional and tumor-associated 11;22 translocations: nonidentical breakpoints on chromosomes 11 and 22. Proc Natl Acad Sci U S A (1986) 1.16
Molecular cloning and primary structure of human chromogranin A (secretory protein I) cDNA. J Biol Chem (1988) 1.16
MR imaging in the tethered spinal cord syndrome. AJR Am J Roentgenol (1989) 1.15
Distinct mechanisms of cell cycle arrest control the decision between differentiation and senescence in human neuroblastoma cells. Proc Natl Acad Sci U S A (2001) 1.15
Insulin-like growth factor II-mediated proliferation of human neuroblastoma. J Clin Invest (1991) 1.15
Differential protooncogene expression characterizes histopathologically indistinguishable tumors of the peripheral nervous system. J Clin Invest (1987) 1.15
Molecular cloning and primary structure of human glial fibrillary acidic protein. Proc Natl Acad Sci U S A (1989) 1.14
p53-dependent G1 arrest and p53-independent apoptosis influence the radiobiologic response of glioblastoma. Int J Radiat Oncol Biol Phys (1996) 1.14
Depressive symptoms in adult coeliac disease. Scand J Gastroenterol (1998) 1.14
Indistinguishable patterns of protooncogene expression in two distinct but closely related tumors: Ewing's sarcoma and neuroepithelioma. Cancer Res (1988) 1.13
Developmental regulation of annexin II (Lipocortin 2) in human brain and expression in high grade glioma. Cancer Res (1992) 1.13
A novel POU homeodomain gene specifically expressed in cells of the developing mammalian nervous system. Nucleic Acids Res (1992) 1.12
Regulation of c-myb expression in human neuroblastoma cells during retinoic acid-induced differentiation. Mol Cell Biol (1988) 1.11
Structure and solution properties of tamarind-seed polysaccharide. Carbohydr Res (1991) 1.11
A repertoire of differentially expressed transcription factors that offers insight into mechanisms of human cytotrophoblast differentiation. Dev Genet (1999) 1.11
Management of chiasmal and hypothalamic gliomas of infancy and childhood with chemotherapy. J Neurosurg (1991) 1.11
In vitro association and phosphorylation of polyoma virus middle T antigen by cellular tyrosyl kinase activity. J Biol Chem (1984) 1.10
Germ-line and somatic p53 gene mutations in multifocal osteogenic sarcoma. Proc Natl Acad Sci U S A (1992) 1.08