Published in Science on April 09, 1976
Where is the evidence that animal research benefits humans? BMJ (2004) 5.99
The answer is 17 years, what is the question: understanding time lags in translational research. J R Soc Med (2011) 4.14
Evaluating "payback" on biomedical research from papers cited in clinical guidelines: applied bibliometric study. BMJ (2000) 3.19
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Comroe and Dripps revisited. Br Med J (Clin Res Ed) (1987) 2.40
Medical progress depends on animal models - doesn't it? J R Soc Med (2008) 1.89
The correlates of research success. Br Med J (Clin Res Ed) (1987) 1.85
Evolution and translation of research findings: from bench to where? PLoS Clin Trials (2006) 1.60
A systematic evaluation of payback of publicly funded health and health services research in Hong Kong. BMC Health Serv Res (2007) 1.54
Lung regeneration: mechanisms, applications and emerging stem cell populations. Nat Med (2014) 1.48
Estimating the NIH efficient frontier. PLoS One (2012) 1.20
Academic medicine: time for reinvention: research needs researching. BMJ (2004) 1.14
International scientific meetings: relation between structure and function. Br Med J (Clin Res Ed) (1985) 1.07
Understanding factors associated with the translation of cardiovascular research: a multinational case study approach. Implement Sci (2014) 1.02
The sickening of medical research: multiple diagnoses and two remedies. Br Med J (Clin Res Ed) (1988) 0.98
History of the development of inhibitors of angiotensin I conversion. Drugs (1985) 0.98
Window panes of eternity. Health, disease, and inherited risk. Yale J Biol Med (1983) 0.88
All change for research. Br Med J (Clin Res Ed) (1987) 0.87
Is the use of sentient animals in basic research justifiable? Philos Ethics Humanit Med (2010) 0.84
Methods and management: NIH administrators, federal oversight, and the Framingham Heart Study. Bull Hist Med (2012) 0.81
Quality of life returns from basic research. Health Res Policy Syst (2010) 0.80
Can animal data translate to innovations necessary for a new era of patient-centred and individualised healthcare? Bias in preclinical animal research. BMC Med Ethics (2015) 0.78
The fourth surgical renaissance? Ann Surg (1980) 0.77
Augmentation of cutaneous wound healing by pharmacologic mobilization of endogenous bone marrow stem cells. J Invest Dermatol (2014) 0.76
Concepts of disease, medical research and the challenges to the schools of the healing professions. Can Vet J (1985) 0.75
The Jeremiah Metzger lecture. Information transfer in the service of Medicine. Trans Am Clin Climatol Assoc (1977) 0.75
A view from the coal face. Br Med J (Clin Res Ed) (1988) 0.75
Cross-fertilization among fields: a seminal event in the progress of biomedical research. J Clin Invest (1994) 0.75
Research and risk. Br Med J (1980) 0.75
Cardiovascular drug discovery: a perspective from a research-based pharmaceutical company. Cold Spring Harb Perspect Med (2014) 0.75
Is medical research in danger of suffering the same fate as the NHS? QJM (2014) 0.75
New advances in analgesic and anxiolytic agents: implications for continued support of basic research. Anesth Prog (1982) 0.75
The Nile in Canada: scientific outlook and society. Can Med Assoc J (1980) 0.75
The NHS is dead: long live the NHS. An open letter to Sir Alec Merrison. Br Med J (1976) 0.75
Why T waves change: a reminiscence and essay. Heart Rhythm (2009) 0.75
The role of the physician-scientist in our evolving society. Rambam Maimonides Med J (2011) 0.75
Cardiac Resuscitation. Ann Surg (1948) 2.70
Ben Franklin and open heart surgery. Circ Res (1974) 2.38
Postoperative Atelectasis and Pneumonia: Diagnosis, Etiology and Management Based upon 1,240 Cases of upper Abdominal Surgery. Ann Surg (1946) 2.13
Editorial: What's locked up? Am Rev Respir Dis (1974) 1.69
LUNG FUNCTION STUDIES. I. THE RATE OF INCREASE OF ARTERIAL OXYGEN SATURATION DURING THE INHALATION OF 100 PER CENT O(2). J Clin Invest (1948) 1.53
A combined fluorescence histochemical and electron microscopic method for studying special monoamine-containing cells (SIF cells). J Comp Neurol (1974) 1.25
Species difference in carotid body response of cat and dog to dopamine and serotonin. Am J Physiol (1972) 1.21
Screening tests of pulmonary function. N Engl J Med (1970) 1.11
Postoperative hyponatremia with the inappropriate release of antidiuretic hormone. Anesthesiology (1966) 1.07
The road from research to new diagnosis and therapy. Science (1978) 1.01
The main functions of the pulmonary circulation. Circulation (1966) 0.97
Stimulation of the carotid chemoreceptors of the dog by dopamine. Proc Natl Acad Sci U S A (1968) 0.97
Measurement of anti-arrhythmic potency of drugs in man: effects of dehydrobenzperidol. Anesthesiology (1967) 0.96
Experimental studies designed to evaluate the management of patients with incurable cancer. Proc Natl Acad Sci U S A (1978) 0.95
Reflex apnea, bradycardia, and hypotension produced by serotonin and phenyldiguanide acting on the nodose ganglia of the cat. Circ Res (1971) 0.94
Who was Alexis who? Am Rev Respir Dis (1978) 0.90
Carotid sinus versus carotid body origin of nicotine and cyanide bradycardia in the dog. Am J Physiol (1971) 0.90
Retrospectroscope. What makes the sky blue? Am Rev Respir Dis (1976) 0.85
Pay dirt: the story of streptomycin. Part I. From Waksman to Waksman. Am Rev Respir Dis (1978) 0.83
Frankenstein, Pickwick, and Ondine. Am Rev Respir Dis (1975) 0.81
Premature science and immature lungs. Part III. The attack on immature lungs. Am Rev Respir Dis (1977) 0.80
The respiratory response to carbon dioxide during Innovar-nitrous oxide anaesthesia in man. Br J Anaesth (1967) 0.80
Pay dirt: the story of streptomycin. Part II. Feldman and Hinshaw; Lehmann. Am Rev Respir Dis (1978) 0.79
Afferent lung denervation by brief inhalation of steam. J Appl Physiol (1973) 0.78
Clinical experience with isoflurane (Forane): preliminary communication. Br J Anaesth (1973) 0.78
Premature science and immature lungs. Part I. Some premature discoveries. Am Rev Respir Dis (1977) 0.77
Answers to a congressman's questions. Circ Res (1969) 0.76
How to succeed in failing without really trying. Am Rev Respir Dis (1976) 0.76
The lung. Sci Am (1966) 0.76
Pulmonary diffusing capacity for carbon monoxide (DLCO). Am Rev Respir Dis (1975) 0.76
Central and reflex control of breathing. Anesth Analg (1990) 0.76
Premature science and immature lungs. Part II. Chemical warfare and the newly born. Am Rev Respir Dis (1977) 0.75
CORRESPONDENCE. Ann Surg (1942) 0.75
Hypotension after morphine. N Engl J Med (1970) 0.75
Roast pig and scientific discovery. Part II. Am Rev Respir Dis (1977) 0.75
Speculation on speculation. Am Rev Respir Dis (1977) 0.75
Roast pig and scientific discovery. Part I. Am Rev Respir Dis (1977) 0.75
The witch doctor, the which doctor, and the wish doctor. Am Rev Respir Dis (1979) 0.75
Out of the mouth of babes. Am Rev Respir Dis (1976) 0.75
The physician and society. E.A. Rovenstine Memorial Lecture. Anesthesiology (1971) 0.75
A sea of air. Am Rev Respir Dis (1975) 0.75
Graduate training in anesthesiology. Surgery (1972) 0.75
Memoir of Austin Lamont. 1905-1969. Trans Stud Coll Physicians Phila (1970) 0.75
Who speaks for basic medical science? Circ Res (1968) 0.75
Retrospectroscope: Publisher's dawdle: an incurable disease? Am Rev Respir Dis (1977) 0.75
The evolution of biomedical science: past, present, future perspectives. J Med Educ (1977) 0.75
Objective analysis of a medical specialty: the anesthesia survey. Clin Anesth (1966) 0.75
T.B. or not T.B.? Part II. The treatment of tuberculosis. Am Rev Respir Dis (1978) 0.75
Patient consent. Anesthesiology (1967) 0.75
How to make Hasenpfeffer. Am Rev Respir Dis (1975) 0.75
The scope and challenge of modern anesthesia. Nurs Clin North Am (1968) 0.75
Retrospectroscope. Flexible minds. Am Rev Respir Dis (1979) 0.75
"... In comes the good air" Part II. Mouth-to-mouth method. Am Rev Respir Dis (1979) 0.75
Bedside research. Am Rev Respir Dis (1978) 0.75
Man-Cans. (Conclusion). The body plethysmograph (body box). Am Rev Respir Dis (1977) 0.75
The inside story. Am Rev Respir Dis (1976) 0.75
Screening to detect health. N Engl J Med (1970) 0.75
Whodunit (and why). Part 1. Am Rev Respir Dis (1976) 0.75
Clinical application of continuous monitoring of respiratory failure. Annu Rev Med (1971) 0.75
Physiologic and pharmacologic studies in human volunteers. Anesthesiology (1971) 0.75
Editorial: Pulmonary research training grants? Am Rev Respir Dis (1974) 0.75
Letter to the Editor. Science (1963) 0.75
Retrospectroscope: man-cans. Am Rev Respir Dis (1977) 0.75
Who's who in world history. Am Rev Respir Dis (1976) 0.75
T.B. or not T.B.? Part I. The cause of tuberculosis. Am Rev Respir Dis (1978) 0.75
. . . the soul of wit. Am Rev Respir Dis (1975) 0.75
Retrospectroscope: ALA be praised?? Am Rev Respir Dis (1980) 0.75
Inflation--1904 model. Am Rev Respir Dis (1975) 0.75
Retrospectroscope: feet on the ground?? Am Rev Respir Dis (1975) 0.75
Retrospectroscope: "tell it like it was". Am Rev Respir Dis (1976) 0.75
"... In comes the good air" Part I. Rise and fall of the Schäfer method. Am Rev Respir Dis (1979) 0.75
First annual Irvine H. Page lecture. A page in the story of hypertension. Cleve Clin Q (1978) 0.75
Appointments to working government councils. Science (1973) 0.75
Pulmonary function tests and the physician. Physiol Pharmacol Physicians (1966) 0.75
More on patient consent. Anesthesiology (1968) 0.75
Fleece of the month?? Am Rev Respir Dis (1978) 0.75
Retrospectroscope: Missed opportunities. Am Rev Respir Dis (1976) 0.75
Whodunit (and why). Part II. Am Rev Respir Dis (1976) 0.75
Hydrogen, balloons, and pressures. Am Rev Respir Dis (1976) 0.75
Publish and/or perish. Am Rev Respir Dis (1976) 0.75
Either-or? (Why not both?) Am Rev Respir Dis (1975) 0.75
Retrospectroscope: the clouded crystal ball. Am Rev Respir Dis (1976) 0.75
Contributions of basic research to clinical medicine. Chest (1971) 0.75
Heart Panel's Report. Science (1974) 0.75
Hypoxia, hyperdynamic circulation, and the hazards of general anesthesia in patients with hepatic cirrhosis. Anesthesiology (1971) 0.75
American Lung Association. Acceptance of the Trudeau Medal for 1974. Am Rev Respir Dis (1974) 0.75