Published in Nature on September 30, 1993
Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor. EMBO J (1997) 3.74
Cell signalling. A tale of two messengers. Nature (1993) 1.88
A novel cycling assay for cellular cADP-ribose with nanomolar sensitivity. Biochem J (2002) 1.55
Cyclic ADP-ribose regulation of ryanodine receptors involved in agonist evoked cytosolic Ca2+ oscillations in pancreatic acinar cells. EMBO J (1994) 1.46
Cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate (NAADP) as messengers for calcium mobilization. J Biol Chem (2012) 1.37
Evidence that the cADPR signalling pathway controls calcium-mediated microneme secretion in Toxoplasma gondii. Biochem J (2005) 1.10
Differential regulation of nicotinic acid-adenine dinucleotide phosphate and cADP-ribose production by cAMP and cGMP. Biochem J (1998) 1.06
Molecular characterization of a novel intracellular ADP-ribosyl cyclase. PLoS One (2007) 1.03
Evidence of a role for cyclic ADP-ribose in long-term synaptic depression in hippocampus. Proc Natl Acad Sci U S A (1999) 1.02
Vascular physiology of a Ca2+ mobilizing second messenger - cyclic ADP-ribose. J Cell Mol Med (2006) 1.02
Cyclic ADP-ribose and calcium-induced calcium release regulate neurotransmitter release at a cholinergic synapse of Aplysia. J Physiol (1998) 0.98
Nicotinamide inhibits cyclic ADP-ribose-mediated calcium signalling in sea urchin eggs. Biochem J (1996) 0.95
Caffeine- and ryanodine-sensitive Ca(2+)-induced Ca2+ release from the endoplasmic reticulum in honeybee photoreceptors. J Gen Physiol (1995) 0.92
Molecular characterization of a novel cell surface ADP-ribosyl cyclase from the sea urchin. Cell Signal (2008) 0.87
Differential effect of pH upon cyclic-ADP-ribose and nicotinate-adenine dinucleotide phosphate-induced Ca2+ release systems. Biochem J (1998) 0.87
Role of Ins(1,4,5)P3, cADP-ribose and nicotinic acid-adenine dinucleotide phosphate in Ca2+ signalling in mouse submandibular acinar cells. Biochem J (2001) 0.87
Nicotinamide-adenine dinucleotide regulates muscarinic receptor-coupled K+ (M) channels in rodent NG108-15 cells. J Physiol (1995) 0.84
Cluster of differentiation 38 (CD38) mediates bile acid-induced acinar cell injury and pancreatitis through cyclic ADP-ribose and intracellular calcium release. J Biol Chem (2013) 0.80
Opposite actions of nitric oxide on cholinergic synapses: which pathways? Proc Natl Acad Sci U S A (1996) 0.80
Cyclic ADP-Ribose and NAADP in Vascular Regulation and Diseases. Messenger (Los Angel) (2013) 0.78
Ectocellular in vitro and in vivo metabolism of cADP-ribose in cerebellum. Biochem J (1996) 0.78
NO-Mediated [Ca2+]cyt Increases Depend on ADP-Ribosyl Cyclase Activity in Arabidopsis. Plant Physiol (2016) 0.77
Characteristics of the NANC post-stimulus ('rebound') contraction of the urinary bladder neck muscle in sheep. Br J Pharmacol (1995) 0.77
The role of ryanodine receptors in the cyclic ADP ribose modulation of the M-like current in rodent m1 muscarinic receptor-transformed NG108-15 cells. J Physiol (1999) 0.76
Interleukin-1 beta stimulation of 45Ca2+ release from rat striatal slices. Br J Pharmacol (1996) 0.76
De novo assembly of a transcriptome from the eggs and early embryos of Astropecten aranciacus. PLoS One (2017) 0.75
Cytosolic interaction of type III human CD38 with CIB1 modulates cellular cyclic ADP-ribose levels. Proc Natl Acad Sci U S A (2017) 0.75
Long-term potentiation of the glutamate-activated inward current induced by 8-Br-cGMP in nerve cell. Dokl Biol Sci (2002) 0.75
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell (1992) 7.06
Association of hormone-replacement therapy with various cardiovascular risk factors in postmenopausal women. The Atherosclerosis Risk in Communities Study Investigators. N Engl J Med (1993) 5.14
The BBC survey of complementary medicine use in the UK. Complement Ther Med (2000) 4.70
Midwife managed delivery unit: a randomised controlled comparison with consultant led care. BMJ (1994) 4.23
Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis. Eur J Immunol (1988) 4.20
Acupuncture: safety first. BMJ (1997) 3.84
Pulsatile intracellular calcium release does not depend on fluctuations in inositol trisphosphate concentration. Nature (1989) 3.65
Purification and biological activity of thymosin, a hormone of the thymus gland. Proc Natl Acad Sci U S A (1972) 3.24
Preparation, assay, and partial purification of a thymic lymphocytopoietic factor (thymosin). Proc Natl Acad Sci U S A (1966) 3.16
Appearance of T-cell markers in bone marrow rosette-forming cells after incubation with thymosin, a thymic hormone. Proc Natl Acad Sci U S A (1971) 3.13
Synthesis and characterization of an octanucleotide containing the EcoRI recognition sequence with a phosphorothioate group at the cleavage site. Biochemistry (1984) 3.03
Life-threatening adverse reactions after acupuncture? A systematic review. Pain (1997) 2.96
How damaged is the biologically active subpopulation of transfected DNA? Mol Cell Biol (1984) 2.88
Expression of a polypeptide containing a dipeptide repeat is confined to the insect stage of Trypanosoma brucei. Nature (1987) 2.86
Search for a resonance decaying into WZ boson pairs in pp collisions. Phys Rev Lett (2010) 2.83
BHD mutations, clinical and molecular genetic investigations of Birt-Hogg-Dubé syndrome: a new series of 50 families and a review of published reports. J Med Genet (2008) 2.79
Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav. Nature (1995) 2.78
A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages. J Exp Med (1997) 2.76
The small subunit of HL-A antigens is beta 2-microglobulin. J Exp Med (1973) 2.68
Fire on an intensive care unit caused by an oxygen cylinder. Anaesthesia (2012) 2.61
Rapid radioimmunoassay diagnosis of Legionnaires' disease: detection and partial characterization of urinary antigen. Ann Intern Med (1981) 2.60
Laryngeal mask airway for coronary artery bypass grafting. Anaesthesia (1991) 2.49
Modulation of cytokine production by transforming growth factor-beta. J Immunol (1989) 2.42
Rapid diagnosis of Legionnaires' disease by latex agglutination. Am Rev Respir Dis (1983) 2.35
The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. EMBO J (1997) 2.34
Rapid diagnosis of Legionnaires' disease by urinary antigen detection. Comparison of ELISA and radioimmunoassay. Am J Med (1982) 2.30
The laryngeal mask airway in pediatric radiotherapy. Anesthesiology (1990) 2.29
The rapid formation of inositol phosphates in human platelets by thrombin is inhibited by prostacyclin. J Biol Chem (1984) 2.28
INFLUENCE OF ADRENAL CORTICAL SECRETION ON BLOOD ELEMENTS. Science (1943) 2.18
Synthesis and configurational analysis of a dinucleoside phosphate isotopically chiral at phosphorus. Stereochemical course of Penicillium citrum nuclease P1 reaction. Biochemistry (1983) 2.18
Standards for reporting interventions in controlled trials of acupuncture: the STRICTA recommendations. Complement Ther Med (2001) 2.13
Studies of the mode of action of adrenal steroids on lymphocytes. Recent Prog Horm Res (1967) 2.09
Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha. Clin Exp Immunol (1988) 2.06
Teichoic acid antibodies in staphylococcal and nonstaphylococcal endocarditis. Ann Intern Med (1972) 2.03
The role of nucleoside diphosphatase in a uridine nucleotide cycle associated with lactose synthesis in rat mammary-gland Golgi apparatus. Biochem J (1977) 2.03
Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation. Nat Immunol (2001) 2.03
Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36). Proc Natl Acad Sci U S A (2004) 2.03
Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. Histopathology (2005) 2.02
A prospective clinical audit of methadone maintenance therapy at the Royal Newcastle Hospital. Med J Aust (1989) 2.01
Detection of interleukin 8 biological activity in synovial fluids from patients with rheumatoid arthritis and production of interleukin 8 mRNA by isolated synovial cells. Eur J Immunol (1990) 2.01
Redundant mechanisms of calcium-induced calcium release underlying calcium waves during fertilization of sea urchin eggs. Science (1993) 1.99
The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways. Proc Natl Acad Sci U S A (1999) 1.98
Isolated congenital ACTH deficiency: a cleavage enzyme defect? Clin Endocrinol (Oxf) (1993) 1.96
Cigarette marketing in Senegal, West Africa. Tob Control (1997) 1.94
Direct inhibition of cyclooxygenase-1 and -2 by the kinase inhibitors SB 203580 and PD 98059. SB 203580 also inhibits thromboxane synthase. J Biol Chem (1998) 1.94
Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-alpha. Eur J Immunol (1991) 1.87
A precision measurement of the mass of the top quark. Nature (2004) 1.87
The causal role for genital ulcer disease as a risk factor for transmission of human immunodeficiency virus. An application of the Bradford Hill criteria. Sex Transm Dis (1997) 1.86
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications. NIDA Res Monogr (1998) 1.86
Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose. Nature (1999) 1.86
Extracts of feverfew inhibit granule secretion in blood platelets and polymorphonuclear leucocytes. Lancet (1985) 1.84
Stereospecificity of nucleases towards phosphorothioate-substituted RNA: stereochemistry of transcription by T7 RNA polymerase. Nucleic Acids Res (1987) 1.82
RECAP--retrosynthetic combinatorial analysis procedure: a powerful new technique for identifying privileged molecular fragments with useful applications in combinatorial chemistry. J Chem Inf Comput Sci (1998) 1.79
Relative abundance of organochlorine pesticides and polychlorinated biphenyls in adipose tissue and serum of women in Long Island, New York. Cancer Epidemiol Biomarkers Prev (1998) 1.77
Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells. Oncogene (1996) 1.77
The efficiency of multilocus DNA fingerprint probes for individualization and establishment of family relationships, determined from extensive casework. Am J Hum Genet (1991) 1.76
Fyn and Lyn phosphorylate the Fc receptor gamma chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway. Blood (2000) 1.75
Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate. Structure (1999) 1.74
Ontogenesis of cell-mediated immunity in murine thymocytes and spleen cells and its acceleration by thymosin, a thymic hormone. J Immunol (1971) 1.73
1,2-Diacylglycerol and phorbol ester inhibit agonist-induced formation of inositol phosphates in human platelets: possible implications for negative feedback regulation of inositol phospholipid hydrolysis. Proc Natl Acad Sci U S A (1985) 1.73
Characterization of the major superoxide dismutase of Staphylococcus aureus and its role in starvation survival, stress resistance, and pathogenicity. J Bacteriol (1999) 1.72
Acupuncture for idiopathic headache. Cochrane Database Syst Rev (2001) 1.72
Neuropsychological dysfunction following repeat concussions in jockeys. J Neurol Neurosurg Psychiatry (2006) 1.71
Tyrosine phosphorylation of the Fc receptor gamma-chain in collagen-stimulated platelets. J Biol Chem (1996) 1.71
Retrospective study of the correlation between the DNA repair protein alkyltransferase and survival of brain tumor patients treated with carmustine. Cancer Res (1996) 1.68
Comprehensive microRNA expression profiling of the hematopoietic hierarchy. Proc Natl Acad Sci U S A (2010) 1.67
Nicotinic acid adenine dinucleotide phosphate (NAADP(+)) is an essential regulator of T-lymphocyte Ca(2+)-signaling. J Cell Biol (2000) 1.67
Tissue selectivity of substance P alkyl esters: suggesting multiple receptors. Eur J Pharmacol (1983) 1.65
Establishment of an aerosol challenge model of tuberculosis in rhesus macaques and an evaluation of endpoints for vaccine testing. Clin Vaccine Immunol (2010) 1.64
The topography of lactose synthesis. Biochem J (1975) 1.64
Influence of thymosin on cell-mediated and humoral immune responses in normal and in immunologically deficient mice. J Immunol (1970) 1.62
Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain. FEBS Lett (1997) 1.62
Cleavage of phosphorothioate-substituted DNA by restriction endonucleases. J Biol Chem (1984) 1.61
Cytokine production in the rheumatoid joint: implications for treatment. Ann Rheum Dis (1990) 1.61
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Peritoneal involvement in stage II colon cancer. Am J Clin Pathol (2003) 1.59
Bacterial endocarditis following open-heart surgery. Ann Thorac Surg (1967) 1.59
Submandibular duct relocation for drooling: a 10-year experience with 194 patients. Otolaryngol Head Neck Surg (1989) 1.58
A novel mutation in the P2Y12 receptor and a function-reducing polymorphism in protease-activated receptor 1 in a patient with chronic bleeding. J Thromb Haemost (2014) 1.58
Acupuncture for recurrent headaches: a systematic review of randomized controlled trials. Cephalalgia (1999) 1.57
Lack of association of epidermal growth factor-, insulin-, and serum-induced mitogenesis with stimulation of phosphoinositide degradation in BALB/c 3T3 fibroblasts. J Biol Chem (1986) 1.57
Diagnosis of bacterial diseases by detection of serum antigens by counterimmunoelectrophoresis, sensitivity, and specificity of detecting Pseudomonas and pneumococcal antigens. J Lab Clin Med (1974) 1.56
Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice. J Clin Invest (1999) 1.56
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
Vasa previa: an avoidable obstetric tragedy. Obstet Gynecol Surv (1999) 1.55
New variant Creutzfeldt-Jakob disease: psychiatric features. Lancet (1997) 1.55
The size of inositol 1,4,5-trisphosphate-sensitive Ca2+ stores depends on inositol 1,4,5-trisphosphate concentration. Biochem J (1990) 1.54
Gender, racial, and geographic differences in the performance of cardiac diagnostic and therapeutic procedures for hospitalized acute myocardial infarction in four states. Am J Cardiol (1997) 1.54
A randomized trial comparing heater probe plus thrombin with heater probe plus placebo for bleeding peptic ulcer. Gastroenterology (2003) 1.54
Measurement of the forward-backward charge asymmetry in top-quark pair production. Phys Rev Lett (2008) 1.53
Multiple facial angiofibromas and collagenomas in patients with multiple endocrine neoplasia type 1. Arch Dermatol (1997) 1.53
Trick or treat?: uneven understanding of mind and emotion and executive dysfunction in "hard-to-manage" preschoolers. J Child Psychol Psychiatry (1998) 1.53
Aortic valve calcification on computed tomography predicts the severity of aortic stenosis. Clin Radiol (2003) 1.52
Inositol 1,3,4,5-tetrakisphosphate is essential for sustained activation of the Ca2+-dependent K+ current in single internally perfused mouse lacrimal acinar cells. J Membr Biol (1989) 1.52
Molecular recognition of inositol polyphosphates by intracellular receptors and metabolic enzymes. Trends Pharmacol Sci (1989) 1.51
Solid-phase radioimmunoassay for immunoglobulin G Staphylococcus aureus antibody in serious staphylococcal infection. Ann Intern Med (1978) 1.51