Published in Carcinogenesis on October 01, 1993
Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling. Proc Natl Acad Sci U S A (2011) 2.13
Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells. Br J Cancer (2004) 1.63
Squamous cell cancers contain a side population of stem-like cells that are made chemosensitive by ABC transporter blockade. Br J Cancer (2008) 1.33
Switch from alphavbeta5 to alphavbeta6 integrin expression protects squamous cell carcinomas from anoikis. J Cell Biol (2004) 1.30
beta1 integrins regulate keratinocyte adhesion and differentiation by distinct mechanisms. Mol Biol Cell (2000) 1.26
Internalization of Staphylococcus aureus by human keratinocytes. Infect Immun (2004) 1.03
Interleukin-1alpha enhances the aggressive behavior of pancreatic cancer cells by regulating the alpha6beta1-integrin and urokinase plasminogen activator receptor expression. BMC Cell Biol (2006) 1.02
A stem cell gene expression profile of human squamous cell carcinomas. Cancer Lett (2008) 1.01
Toll-like receptors: role in dermatological disease. Mediators Inflamm (2010) 0.93
Binding of TGF-beta1 latency-associated peptide (LAP) to alpha(v)beta6 integrin modulates behaviour of squamous carcinoma cells. Br J Cancer (2002) 0.92
Inhibition of a novel specific neuroglial integrin signaling pathway increases STAT3-mediated CNTF expression. Cell Commun Signal (2013) 0.79
The Periodontal Pathogen Porphyromonas gingivalis Preferentially Interacts with Oral Epithelial Cells in S Phase of the Cell Cycle. Infect Immun (2016) 0.75
Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell (1993) 5.86
Stem cell patterning and fate in human epidermis. Cell (1995) 5.22
Regulation of development and differentiation by the extracellular matrix. Development (1993) 4.13
The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis. Development (1999) 3.31
c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny. Curr Biol (2001) 3.22
Fibronectin inhibits the terminal differentiation of human keratinocytes. Nature (1989) 2.77
Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters. Curr Biol (2000) 2.58
Stem cells: the generation and maintenance of cellular diversity. Development (1989) 2.54
Presence of human herpesvirus 8 variants in the oral tissues of human immunodeficiency virus-infected persons. J Infect Dis (1997) 2.49
Stratification and terminal differentiation of cultured epidermal cells. Nature (1982) 2.44
c-Myc promotes differentiation of human epidermal stem cells. Genes Dev (1997) 2.37
Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis. Cell (1995) 2.24
The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development. Cell (2000) 2.22
Involucrin synthesis is correlated with cell size in human epidermal cultures. J Cell Biol (1981) 2.14
Signaling via beta1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro. Proc Natl Acad Sci U S A (1999) 2.06
Evidence that cadherins play a role in the downregulation of integrin expression that occurs during keratinocyte terminal differentiation. J Cell Biol (1994) 2.05
Calcium-induced reorganization of desmosomal components in cultured human keratinocytes. J Cell Biol (1984) 2.00
An audit of the efficacy of the oral brush biopsy technique in a specialist Oral Medicine unit. Oral Oncol (2004) 2.00
Selective migration of terminally differentiating cells from the basal layer of cultured human epidermis. J Cell Biol (1984) 1.93
Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules. Proc Natl Acad Sci U S A (1991) 1.91
beta-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion. Development (1999) 1.89
Juvenile ossifying fibroma. An analysis of eight cases and a comparison with other fibro-osseous lesions. J Oral Pathol Med (2000) 1.88
Osteosarcoma of the jaws: a 30-year retrospective review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2000) 1.74
Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytes. J Cell Sci (1996) 1.74
Clinico-pathological features of squamous cell carcinoma of the oral cavity in patients <40 years of age. J Oral Pathol Med (2005) 1.67
Proliferative heterogeneity in the human prostate: evidence for epithelial stem cells. Lab Invest (2000) 1.66
Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon gamma in the epidermis. J Exp Med (1997) 1.63
Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells. Br J Cancer (2004) 1.63
DNA amplification is rare in normal human cells. Proc Natl Acad Sci U S A (1990) 1.63
Brief report: a single neoplastic clone in sequential biopsy specimens from a patient with primary gastric-mucosa-associated lymphoid-tissue lymphoma and Sjögren's syndrome. N Engl J Med (1993) 1.62
Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis. J Clin Invest (1992) 1.58
Involucrin and other markers of keratinocyte terminal differentiation. J Invest Dermatol (1983) 1.58
Photodynamic therapy of oral cancer: photosensitisation with systemic aminolaevulinic acid. Lancet (1993) 1.54
Epithelial cell differentiation pathways in the human prostate: identification of intermediate phenotypes by keratin expression. J Histochem Cytochem (2001) 1.50
Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin. J Cell Biol (1997) 1.50
Regulation of cell surface beta 1 integrin levels during keratinocyte terminal differentiation. J Cell Biol (1995) 1.48
Expression of beta 1, beta 3, beta 4, and beta 5 integrins by human epidermal keratinocytes and non-differentiating keratinocytes. J Cell Biol (1991) 1.42
Measurement of the rate of epidermal terminal differentiation: expression of involucrin by S-phase keratinocytes in culture and in psoriatic plaques. J Invest Dermatol (1987) 1.42
Two subpopulations of differentiated chondrocytes identified with a monoclonal antibody to keratan sulfate. J Cell Biol (1985) 1.41
Integrin expression during human epidermal development in vivo and in vitro. Development (1991) 1.41
The plakin family: versatile organizers of cytoskeletal architecture. Curr Opin Genet Dev (1997) 1.39
Asymmetric stem-cell divisions define the architecture of human oesophageal epithelium. Curr Biol (2000) 1.39
Photodynamic therapy using 5-aminolevulinic acid for premalignant and malignant lesions of the oral cavity. Cancer (1996) 1.37
Effect of growth environment on spatial expression of involucrin by human epidermal keratinocytes. Arch Dermatol Res (1987) 1.36
Opportunistic screening for oral cancer and precancer in general dental practice: results of a demonstration study. Br Dent J (2003) 1.35
Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin. J Cell Biol (1996) 1.35
Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis. Proc Natl Acad Sci U S A (2003) 1.33
A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis. J Clin Invest (2001) 1.31
A clinicopathologic and immunohistochemical analysis of melanotic neuroectodermal tumor of infancy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2002) 1.28
Influence of beta1 integrins on epidermal squamous cell carcinoma formation in a transgenic mouse model: alpha3beta1, but not alpha2beta1, suppresses malignant conversion. Cancer Res (2001) 1.28
Regulation by vitamin A of envelope cross-linking in cultured keratinocytes derived from different human epithelia. Mol Cell Biol (1982) 1.27
The range and demographics of salivary gland tumours diagnosed in a UK population. Oral Oncol (2007) 1.26
beta1 integrins regulate keratinocyte adhesion and differentiation by distinct mechanisms. Mol Biol Cell (2000) 1.26
AlphaVbeta6 integrin promotes invasion of squamous carcinoma cells through up-regulation of matrix metalloproteinase-9. Int J Cancer (2001) 1.24
Analysis of cultured keratinocytes from a transgenic mouse model of psoriasis: effects of suprabasal integrin expression on keratinocyte adhesion, proliferation and terminal differentiation. Exp Dermatol (1999) 1.24
Transgenic mice expressing IFN-gamma in the epidermis have eczema, hair hypopigmentation, and hair loss. J Invest Dermatol (1997) 1.24
Subcellular distribution of envoplakin and periplakin: insights into their role as precursors of the epidermal cornified envelope. J Cell Biol (2000) 1.23
Photodynamic therapy: an effective, but non-selective treatment for superficial cancers of the oral cavity. Int J Cancer (1997) 1.22
Changes in the expression of alpha v integrins in oral squamous cell carcinomas. J Oral Pathol Med (1997) 1.21
Functional significance of CD9 association with beta 1 integrins in human epidermal keratinocytes. Cell Adhes Commun (1996) 1.20
Transcriptional and post-translational regulation of beta 1 integrin expression during keratinocyte terminal differentiation. J Biol Chem (1992) 1.19
Progress in determining the malignant potential of oral lesions. J Oral Pathol Med (2003) 1.19
Myofibromas presenting in the oral cavity: a series of 9 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2000) 1.18
Expression of the alphavbeta6 integrin promotes migration and invasion in squamous carcinoma cells. J Invest Dermatol (2001) 1.18
Adenomatoid hyperplasia of oral minor salivary glands. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (1995) 1.18
Differentiation of embryonal stem cells into keratinocytes: comparison of wild-type and beta 1 integrin-deficient cells. Dev Biol (1996) 1.17
The frequency of fungal infection in biopsies of oral mucosal lesions. Oral Dis (1998) 1.17
Sources and patterns of referrals of oral cancer: role of general practitioners. Br Med J (Clin Res Ed) (1986) 1.17
Calcium-induced changes in distribution and solubility of cadherins, integrins and their associated cytoplasmic proteins in human keratinocytes. Cell Adhes Commun (1995) 1.15
Detection of human papillomavirus DNA in biopsies of human oral tissue. Br J Cancer (1987) 1.15
Evidence that apoptosis and terminal differentiation of epidermal keratinocytes are distinct processes. Exp Dermatol (1999) 1.14
Changes in expression of members of the fos and jun families and myc network during terminal differentiation of human keratinocytes. Oncogene (1995) 1.13
Biochemical specificity of Xenopus notochord. Differentiation (1985) 1.13
Oral yeast carriage correlates with presence of oral epithelial dysplasia. Oral Oncol (2002) 1.12
Current concepts of autoimmune exocrinopathy: immunologic mechanisms in the salivary pathology of Sjögren's syndrome. Crit Rev Oral Biol Med (1996) 1.12
p53 expression in odontogenic keratocyst epithelium. J Oral Pathol Med (1996) 1.12
Production of scatter factor by ndk, a strain of epithelial cells, and inhibition of scatter factor activity by suramin. J Cell Sci (1991) 1.12
Optimised retroviral infection of human epidermal keratinocytes: long-term expression of transduced integrin gene following grafting on to SCID mice. Gene Ther (1998) 1.11
Matrix metalloproteinases and oral cancer. Oral Oncol (1999) 1.11
Towards gene therapy for haemophilia B using primary human keratinocytes. Nat Genet (1993) 1.10
Comparison of integrin, cadherin, and catenin expression in squamous cell carcinomas of the oral cavity. J Pathol (1998) 1.10
Expression of Mcm2, geminin and Ki67 in normal oral mucosa, oral epithelial dysplasias and their corresponding squamous-cell carcinomas. Br J Cancer (2009) 1.08
Photodynamic effects of toluidine blue on human oral keratinocytes and fibroblasts and Streptococcus sanguis evaluated in vitro. Lasers Surg Med (1996) 1.08
DNA ploidy analysis by image cytometry helps to identify oral epithelial dysplasias with a high risk of malignant progression. Oral Oncol (2008) 1.05
Evaluation of a screening test for the early detection of oral cancer and precancer. Community Dent Health (1995) 1.04
Xenografts of human ameloblastoma tissue and odontogenic mesenchyme to hypothymic mice. Transplantation (1982) 1.04
Cell adhesion molecules and oral cancer. Crit Rev Oral Biol Med (2001) 1.03
Characterisation of eight monoclonal antibodies to involucrin. Hybridoma (1992) 1.03
Expression of Mcm-2, Ki-67 and geminin in benign and malignant salivary gland tumours. J Oral Pathol Med (2008) 1.02
Photodynamic therapy using mTHPC for malignant disease in the oral cavity. Int J Cancer (1997) 1.02
Deletion mapping defines three discrete areas of allelic imbalance on chromosome arm 8p in oral and oropharyngeal squamous cell carcinomas. Genes Chromosomes Cancer (1997) 1.02
Differential expression of bcl-2 and bax in squamous cell carcinomas of the oral cavity. Eur J Cancer B Oral Oncol (1996) 1.01
Gene targeting of envoplakin, a cytoskeletal linker protein and precursor of the epidermal cornified envelope. Mol Cell Biol (2001) 1.01
Dermal fibroblast-derived growth factors restore the ability of beta(1) integrin-deficient embryonal stem cells to differentiate into keratinocytes. Dev Biol (2001) 1.01
alpha v beta 6 Integrin upregulates matrix metalloproteinase 9 and promotes migration of normal oral keratinocytes. J Invest Dermatol (2001) 1.00
Integrin expression in normal, hyperplastic, dysplastic, and malignant oral epithelium. J Pathol (1993) 1.00