PubRank

A Dray

Author PubWeight™ 109.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Synaptic mechanisms in the substantia nigra. J Pharm Pharmacol 1976 2.54
2 Antagonism of 5-hydroxytryptamine by LSD 25 in the central nervous system: a possible neuronal basis for the actions of LSD 25. Br J Pharmacol 1970 2.49
3 Morphine and neurotransmitter substances: Microiontophoretic study in the rat brain stem. Br J Pharmacol 1974 1.65
4 An in vitro study of the properties of single vagal afferents innervating guinea-pig airways. J Physiol 1993 1.44
5 Proceedings: Comparison of circling behaviour following unilateral inhibition of GABA-transaminase or discrete electroyltic lesioning in the rat substantia nigra. Br J Pharmacol 1975 1.42
6 Chemical activation of nociceptive peripheral neurones. Br Med Bull 1991 1.41
7 Modification of the responses of brain stem neurones to transmitter substances by anaesthetic agents. Br J Pharmacol 1973 1.34
8 Effects of capsazepine against capsaicin- and proton-evoked excitation of single airway C-fibres and vagus nerve from the guinea-pig. Neuroscience 1995 1.28
9 Modulation of spinal excitability: co-operation between neurokinin and excitatory amino acid neurotransmitters. Trends Neurosci 1994 1.27
10 Depression of synaptic excitation and of amino acid induced excitatory responses of spinal neurones by D-alpha-aminoadipate, alpha,epsilon-diaminopimelic acid and HA-966. Eur J Pharmacol 1977 1.27
11 D-alpha-Aminoadipate as a selective antagonist of amino acid-induced and synaptic excitation of mammalian spinal neurones. Nature 1978 1.26
12 Kinins and kinin receptors in the nervous system. Neurochem Int 1995 1.25
13 The effects of different anaesthetics on responses of brain stem neurones to iontophoretically applied transmitter substances. Br J Pharmacol 1972 1.24
14 Evidence for the existence of a raphe projection to the substantia nigra in rat. Brain Res 1976 1.18
15 Inhibition of urinary bladder contractions by a spinal action of morphine and other opioids. J Pharmacol Exp Ther 1984 1.15
16 Antinociceptive activity of the bradykinin B1 and B2 receptor antagonists, des-Arg9, [Leu8]-BK and HOE 140, in two models of persistent hyperalgesia in the rat. Pain 1993 1.15
17 Caudate stimulation and substantia nigra activity in the rat. J Physiol 1976 1.13
18 Cellular mechanism of action of resiniferatoxin: a potent sensory neuron excitotoxin. Brain Res 1990 1.12
19 Substance P in the substantia nigra. Brain Res 1976 1.10
20 Reversal of the action of amino acid antagonists by barbiturates and other hypnotic drugs. Br J Pharmacol 1978 1.10
21 Analogues of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 3. The hydrophobic side-chain "C-region". J Med Chem 1993 1.07
22 The physiology and pharmacology of mammalian basal ganglia. Prog Neurobiol 1980 1.07
23 D-alpha-aminoadipate, alpha, epsilon-diominopimelic acid and HA-966 as antagonists of amino acid-induced and synpatic excitation of mammalian spinal neurones in vivo. Brain Res 1978 1.07
24 Analogues of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 1. The aromatic "A-region". J Med Chem 1993 1.06
25 Barbiturate reversal of amino acid antagonism produced by convulsant agents. Nature 1976 1.06
26 Actions and interactions of microiontophoretically applied morphine with transmitter substances on brain stem neurones. Br J Pharmacol 1973 1.05
27 Selective antagonism of capsaicin by capsazepine: evidence for a spinal receptor site in capsaicin-induced antinociception. Br J Pharmacol 1991 1.04
28 Capsazepine, a novel capsaicin antagonist, selectively antagonises the effects of capsaicin in the mouse spinal cord in vitro. Neurosci Lett 1991 1.03
29 Short-latency excitation of brain stem neurones in the rat by acetylcholine. Br J Pharmacol 1972 1.02
30 Epidural opiates and urinary retention: new models provide new insights. Anesthesiology 1988 1.01
31 Stimulation of guinea-pig tracheal afferent fibres by non-isosmotic and low-chloride stimuli and the effect of frusemide. J Physiol 1995 1.01
32 The striatum and substantia nigra: a commentary on their relationships. Neuroscience 1979 1.01
33 Sensitization of peripheral afferent fibres in the in vitro neonatal rat spinal cord-tail by bradykinin and prostaglandins. Neuroscience 1993 1.00
34 Analogues of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 2. The amide bond "B-region". J Med Chem 1993 1.00
35 Knockdown of spinal metabotropic glutamate receptor 1 (mGluR(1)) alleviates pain and restores opioid efficacy after nerve injury in rats. Br J Pharmacol 2001 0.97
36 Effects of enkephalin and morphine on Renshaw cells in feline spinal cord. Nature 1976 0.97
37 Antagonism by LSD to effects of 5-HT on single neurones. Brain Res 1969 0.96
38 Differential sensitivity of presumed dopaminergic and non-dopaminergic neurones in rat substantia nigra to electrophoretically applied substance P. Neurosci Lett 1982 0.95
39 Opioids suppress spontaneous activity of polymodal nociceptors in rat paw skin induced by ultraviolet irradiation. Neuroscience 1994 0.93
40 Analogues of capsaicin with agonist activity as novel analgesic agents: structure-activity studies. 4. Potent, orally active analgesics. J Med Chem 1996 0.92
41 Pharmacological and electrophysiological studies of morphine and enkephalin on rat supraspinal neurones and cat spinal neurones. Br J Pharmacol 1978 0.92
42 Effects of lysergic acid derivatives on 5-hydroxytryptamine excitation of brain stem neurones. Br J Pharmacol 1970 0.91
43 A spinal mechanism of action is involved in the antinociception produced by the capsaicin analogue NE 19550 (olvanil). Pain 1990 0.91
44 Effects of D-alpha-aminoadipate on physiologically evoked responses of cat dorsal horn neurones. Experientia 1979 0.90
45 Substance P and opiate receptors. Nature 1977 0.90
46 Pro-nociceptive effects of neuromedin U in rat. Neuroscience 2003 0.90
47 Morphine and the centrally-mediated inhibition of urinary bladder motility in the rat. Brain Res 1984 0.89
48 5-Hydroxytryptamine-induced sensitization and activation of peripheral fibres in the neonatal rat are mediated via different 5-hydroxytryptamine-receptors. Neuroscience 1992 0.89
49 Opioid receptor subtypes involved in the central inhibition of urinary bladder motility. Eur J Pharmacol 1984 0.89
50 Priming enhances endotoxin-induced thermal hyperalgesia and mechanical allodynia in rats. Brain Res 1998 0.89
51 Central delta-opioid receptor interactions and the inhibition of reflex urinary bladder contractions in the rat. Br J Pharmacol 1985 0.88
52 Injury-induced plasticity of spinal reflex activity: NK1 neurokinin receptor activation and enhanced A- and C-fiber mediated responses in the rat spinal cord in vitro. J Neurosci 1994 0.87
53 Selective delta-opioid receptor antagonism by ICI 174,864 in the central nervous system. Peptides 1985 0.86
54 Leukemia inhibitory factor induces mechanical allodynia but not thermal hyperalgesia in the juvenile rat. Neuroscience 1996 0.86
55 Synaptic activation of dorsal horn neurons by selective C-fibre excitation with capsaicin in the mouse spinal cord in vitro. Neuroscience 1992 0.86
56 Effects of substance P on adult rat sensory ganglion neurones in vitro. Neurosci Lett 1982 0.85
57 Ions in the fire: recent ion-channel research and approaches to pain therapy. Trends Pharmacol Sci 1999 0.85
58 The dorsal and medial raphe projections to the substantia nigra in the rat: electrophysiological, biochemical and behavioural observations. Brain Res 1978 0.85
59 Opioids and central inhibition of urinary bladder motility. Eur J Pharmacol 1984 0.85
60 Comparison of bicuculline methochloride with bicuculline and picrotoxin as antagonists of amino acid and monoamine depression of neurones in the rat brainstem. Neuropharmacology 1975 0.85
61 Spinal opioid receptors and inhibition of urinary bladder motility in vivo. Neurosci Lett 1984 0.85
62 Stimulation of afferent fibres of the guinea-pig ureter evokes potentials in inferior mesenteric ganglion neurones. J Physiol 1988 0.84
63 Nerve growth factor induces mechanical allodynia associated with novel A fibre-evoked spinal reflex activity and enhanced neurokinin-1 receptor activation in the rat. Pain 1995 0.84
64 Actions of capsaicin on mouse dorsal root ganglion cells in vitro. Neurosci Lett 1993 0.84
65 Pharmacological characterization of the effects of 5-hydroxytryptamine and different prostaglandins on peripheral sensory neurons in vitro. Agents Actions 1993 0.83
66 Activity of deep dorsal horn neurons in the anaesthetized rat during hyperalgesia of the hindpaw induced by ultraviolet irradiation. Neuroscience 1993 0.83
67 Benzodiazepines: GABA and glycine receptors on single neurons in the rat medulla. J Pharm Pharmacol 1976 0.83
68 Supraspinal and spinal mechanisms in morphine-induced inhibition of reflex urinary bladder contractions in the rat. Neuroscience 1987 0.83
69 Neuropeptide FF attenuates allodynia in models of chronic inflammation and neuropathy following intrathecal or intracerebroventricular administration. Eur J Pharmacol 2000 0.82
70 Comparison of the sensory threshold in healthy human volunteers with the sensory nerve response of the rat in vitro hindlimb skin and saphenous nerve preparation on cutaneous electrical stimulation. J Hand Surg Br 1995 0.82
71 Capsaicin-induced activation of fine afferent fibres from rat skin in vitro. Neuroscience 1993 0.82
72 Cobalt uptake enables identification of capsaicin- and bradykinin-sensitive subpopulations of rat dorsal root ganglion cells in vitro. Neuroscience 1993 0.82
73 In vivo antinociceptive activity of anti-rat mGluR1 and mGluR5 antibodies in rats. Neuroreport 1998 0.82
74 LSD's effect on neuron populations in visual cortex gauged by transient responses of extracellular potassium evoked by optical stimuli. Neurosci Lett 1979 0.82
75 Regulation of bradykinin sensitivity in peripheral sensory fibres of the neonatal rat by nitric oxide and cyclic GMP. Neuropharmacology 1994 0.81
76 Bradykinin depolarises the rat isolated superior cervical ganglion via B2 receptor activation. Neurosci Lett 1995 0.81
77 Tetramethylenedisulphotetramine and amino acid inhibition in the rat brain. Neuropharmacology 1975 0.81
78 Proenkephalin A fragments exhibit spinal and supraspinal opioid activity in vivo. J Pharmacol Exp Ther 1985 0.80
79 Antinociception produced by capsaicin: spinal or peripheral mechanism? Eur J Pharmacol 1990 0.80
80 Metabotropic glutamate receptor activation contributes to nociceptive reflex activity in the rat spinal cord in vitro. Neuroscience 1996 0.80
81 Depression and facilitation of synaptic responses in cat dorsal horn by substance P administered into substantia gelatinosa. Life Sci 1980 0.80
82 Bromocriptine and dopamine-receptor stimulation. J Pharm Pharmacol 1976 0.79
83 Mu and delta opioid ligands inhibit reflex contractions of the urinary bladder in the rat by different central mechanisms. Neuropharmacology 1987 0.79
84 Regulation of nigro-striatal dopaminergic neurotransmission in the rat. Neuropharmacology 1977 0.79
85 Evidence that naloxonazine produces prolonged antagonism of central delta opioid receptor activity in vivo. Brain Res 1984 0.79
86 Serotonin in the basal ganglia: functions and interactions with other neuronal pathways. J Physiol (Paris) 1981 0.79
87 Endorphins and the central inhibition of urinary bladder motility. Peptides 1984 0.79
88 Possible branching of myelinated primary afferent fibres in the dorsal root of the rat. Brain Res 1995 0.78
89 The effects of microiontophoretically applied morphine and transmitter substances in rats during chronic treatment and after withdrawl from morphine. Br J Pharmacol 1974 0.78
90 Vascular effects of substance P change synaptic responsiveness of cat dorsal horn neurons. Life Sci 1980 0.78
91 Non-cholinergic synaptic potentials mediated by lumbar colonic nerve in the guinea-pig inferior mesenteric ganglion in vitro. Neuroscience 1988 0.78
92 Actions of enkephalin and morphine on spinal cord and brain stem neurones [proceedings]. Br J Pharmacol 1976 0.77
93 Spinal delta-opioid receptors mediate suppression of systemic SNC80 on excitability of the flexor reflex in normal and inflamed rat. Eur J Pharmacol 2001 0.77
94 Contribution of NK1 and NK2 receptor activation to high threshold afferent fibre evoked ventral root responses in the rat spinal cord in vitro. Brain Res 1993 0.77
95 Iontophoresis of LSD: effects on responses of single cortical neurones to visual stimulation. Brain Res 1979 0.77
96 Effects of alpha-flupenthixol on dopamine and 5-hydroxytryptamine responses of substantia nigra neurones. Neuropharmacology 1976 0.77
97 Effects of caudate stimulation and micro-iontophoretically applied substances on neurones in the rat substantia nigra. J Physiol 1975 0.77
98 Tachykinin induced regulation of excitatory amino acid responses in the rat spinal cord in vitro. Neurosci Lett 1994 0.77
99 Meptazinol: unusual in vivo opioid receptor activity at supraspinal and spinal sites. Neuropharmacology 1986 0.77
100 The effects of NK-1 and NK-2 receptor antagonists on the capsaicin evoked synaptic response in the rat spinal cord in vitro. Regul Pept 1993 0.77
101 No evidence for contribution of nitric oxide to spinal reflex activity in the rat spinal cord in vitro. Neurosci Lett 1995 0.77
102 Hyperalgesia in rats following intracerebroventricular administration of endotoxin: effect of bradykinin B1 and B2 receptor antagonist treatment. Pain 1997 0.76
103 The pro-enkephalin A derivative, peptide E, is centrally processed to active fragments. Proc West Pharmacol Soc 1984 0.76
104 Cobalt accumulation in neurons expressing ionotropic excitatory amino acid receptors in young rat spinal cord: morphology and distribution. J Comp Neurol 1994 0.76
105 Development of hyperthermia following intracerebroventricular administration of endotoxin in the rat: effect of kinin B1 and B2 receptor antagonists. Br J Pharmacol 1996 0.76
106 The proenkephalin A fragment, peptide E: central processing and CNS activity in vivo. Eur J Pharmacol 1985 0.76
107 Opioid inhibition of reflex urinary bladder contractions: dissociation of supraspinal and spinal mechanisms. Brain Res 1985 0.76
108 Effects of the venom of the Southern Pacific rattlesnake, Crotalus viridis helleri, and its fractions on striated and smooth muscle. Proc West Pharmacol Soc 1984 0.76
109 The involvement of afferent nerve terminals in the stimulation of ion transport by bradykinin in rat isolated colon. Br J Pharmacol 1988 0.76
110 Projections from nucleus accumbens to globus pallidus and substantia nigra in the rat. Experientia 1978 0.76
111 Opioid receptor ligands in the neonatal rat spinal cord: binding and in vitro depression of the nociceptive responses. Br J Pharmacol 1990 0.75
112 Extracellular recording in rat substantia nigra. J Physiol 1975 0.75
113 The role of neurokinin and N-methyl-D-aspartate receptors in synaptic transmission from capsaicin-sensitive primary afferents in the rat spinal cord in vitro. Neuroscience 1993 0.75
114 Proceedings: Evaluation of iontophoretic N-methylbicuculline and other inhibitory amino-acid antagonists in rat brain stem. Br J Pharmacol 1974 0.75
115 Novel pharmacological strategies for analgesia. Ann Rheum Dis 1996 0.75
116 Observations on the pharmacology of cholinoceptive neurones in the rat brain stem. Br J Pharmacol 1976 0.75
117 Centrally administered beta-endorphin produces prolonged changes in delta-opioid ligand activity in vivo. Eur J Pharmacol 1986 0.75
118 Development of hyperthermia and hyperalgesia following intracerebroventricular administration of endotoxin in the rat: effect of kinin B1 and B2 receptor antagonists. Immunopharmacology 1996 0.75
119 Noradrenaline artefacts. Nat New Biol 1972 0.75
120 The proenkephalin A fragment metorphamide shows supraspinal and spinal opioid activity in vivo. Peptides 1985 0.75
121 Proceedings: A raphe-substantia nigra projection in the rat. J Physiol 1976 0.75
122 Neuropeptide Y depresses reflex urinary bladder contractions in rats and modifies central activity of opioid agonists. Peptides 1986 0.75
123 The effects of ethanolamine-O-sulphate injection into the rat substantia nigra: electrophysiological studies. Brain Res 1978 0.75
124 A comparison of the release of substance P and some synthetic analogues from micropipettes by microiontophoresis or pressure. Neuropharmacology 1983 0.75
125 Changes in amino acid sensitivity during polypeptide "desensitisation". Nature 1976 0.75
126 Motilin acts within the CNS to inhibit urinary bladder contractions. Life Sci 1984 0.75
127 Actions of neuropeptide K and calcitonin gene-related peptide on inferior mesenteric ganglion cells--tachykinin interactions with non-cholinergic potentials evoked by ureteric nerve stimulation. Neurosci Lett 1988 0.75
128 Commissioning. Life preservers. Health Serv J 1996 0.75
129 Methiothepin and a 5-HT pathway to rat substantia nigra. Experientia 1977 0.75
130 Selective depression of nociceptive responses of dorsal horn neurones by SNC 80 in a perfused hindquarter preparation of adult mouse. Neuroscience 2001 0.75
131 Prolonged in vivo antagonism of central mu- and delta-opioid receptor activity by beta-funal trexamine. Life Sci 1985 0.75
132 The saphenous nerve in foot and ankle surgery: its variable anatomy and relevance. Foot Ankle Surg 2012 0.75
133 Immunochemical detection of photoaffinity-labelled capsaicin-binding proteins from sensory neurons. FEBS Lett 1990 0.75
134 The rat urinary bladder. A novel preparation for the investigation of central opioid activity in vivo. J Pharmacol Methods 1985 0.75
135 The effects of LSD and some analogues on the responses of single cortical neurons of the cat to optical stimulation. Brain Res 1980 0.75
136 A simple method for the construction of coaxial multibarrelled micropipettes with exchangeable components. J Neurosci Methods 1982 0.75
137 Naloxonazine and opioid-induced inhibition of reflex urinary bladder contractions. Neuropharmacology 1987 0.75
138 Peptidergic afferents: physiological aspects. Prog Brain Res 1995 0.75