Published in Nucleic Acids Res on March 25, 1995
Synthesis and evaluation of some properties of chimeric oligomers containing PNA and phosphono-PNA residues. Nucleic Acids Res (1998) 0.95
Arylsulfonyltetrazoles, new coupling reagents and further improvements in the triester method for the synthesis of deoxyribooligonucleotides. Nucleic Acids Res (1977) 8.92
Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc Natl Acad Sci U S A (1978) 7.90
Antisense oligonucleotides as therapeutic agents--is the bullet really magical? Science (1993) 5.50
Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proc Natl Acad Sci U S A (1978) 4.65
Some observations relating to the oximate ion promoted unblocking of oligonucleotide aryl esters. Nucleic Acids Res (1981) 3.25
Antisense and antigene properties of peptide nucleic acids. Science (1992) 3.04
Derivatization of controlled pore glass beads for solid phase oligonucleotide synthesis. Biotechniques (1988) 2.93
Synthesis of oligoribonucleotides based on the facile cleavage of methyl phosphotriester intermediates. J Am Chem Soc (1977) 2.85
Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines. Science (1993) 2.56
Modified deoxyoligonucleotides stable to exonuclease degradation in serum. Nucleic Acids Res (1991) 2.54
Solid-phase syntheses of oligodeoxyribonucleoside methylphosphonates. Biochemistry (1986) 2.00
Oligonucleotide analogues as potential chemotherapeutic agents. Pharm Res (1988) 1.78
Antisense oligonucleotides made of 2'-O-alkylRNA: their properties and applications in RNA biochemistry. FEBS Lett (1993) 1.64
Delivery of antisense oligonucleotides by poly(L-lysine) conjugation and liposome encapsulation. Anticancer Drug Des (1993) 1.61
Synthesis and enzymatic properties of deoxyribooligonucleotides containing methyl and phenylphosphonate linkages. Nucleic Acids Res (1979) 1.61
Site specificity of the inhibitory effects of oligo(nucleoside methylphosphonate)s complementary to the acceptor splice junction of herpes simplex virus type 1 immediate early mRNA 4. Proc Natl Acad Sci U S A (1989) 1.54
Synthesis, hybridization properties and antiviral activity of lipid-oligodeoxynucleotide conjugates. Nucleic Acids Res (1990) 1.32
L-DNAs as potential antimessenger oligonucleotides: a reassessment. Nucleic Acids Res (1993) 1.23
The synthesis of 6'-deoxyhomonucleoside-6'-phosphonic acids. J Am Chem Soc (1968) 1.22
Antiviral activity of conjugates between poly(L-lysine) and synthetic oligodeoxyribonucleotides. Gene (1988) 1.14
The case of sulfonation in the chemical synthesis of oligonucleotides. Nucleic Acids Res (1980) 1.11
Improved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide. Nucleic Acids Res (1994) 1.10
Antibody-targeted liposomes containing oligodeoxyribonucleotides complementary to viral RNA selectively inhibit viral replication. Proc Natl Acad Sci U S A (1990) 1.09
Synthesis of nucleic acid methylphosphonates via the 1-hydroxybenzotriazole phosphotriester approach. Nucleic Acids Res (1986) 0.98
Application of new catalytic phosphate protecting groups for the highly efficient phosphotriester oligonucleotide synthesis. Nucleic Acids Res (1986) 0.91
Synthesis of isosteric phosphonate analogs of some biologically important phosphodiesters. J Am Chem Soc (1970) 0.91
Synthesis and properties of adenosine oligonucleotide analogues containing methylene groups in place of phosphodiester 5'-oxygens. Biochemistry (1993) 0.80
Studies directed towards efficient synthesis of oligo-5'-deoxy-5-C-(phosphonomethyl)deoxyribonucleosides. Nucleic Acids Symp Ser (1991) 0.78
Convenient synthesis of dinucleotide methylphosphonates. Nucleic Acids Symp Ser (1991) 0.77
NMR studies of a complex of RNAse from Penicillium brevicompactum with dinucleoside phosphonate and the implications for the mechanism of enzyme action. Biochim Biophys Acta (1993) 0.77
Arylsulfonyltetrazoles, new coupling reagents and further improvements in the triester method for the synthesis of deoxyribooligonucleotides. Nucleic Acids Res (1977) 8.92
Cloned synthetic lac operator DNA is biologically active. Nature (1976) 2.59
Evaluation of some new condensing reagents for hydrogenphosphonate diester formation. Nucleic Acids Symp Ser (1987) 1.20
5'-Hydrogenphosphonates of anti-HIV nucleoside analogues revisited: controversial mode of action. Antiviral Res (1993) 0.77
Synthesis of phospholipids and nucleoside-phospholipid conjugates via hydrogenphosphonate intermediates. Nucleic Acids Symp Ser (1987) 0.77
Molecular and crystal structure of Sp-thymidin-3'-yl 4-thiothymidin-5'-yl methylphosphonate. Nucleic Acids Res (1993) 0.75
Solid support synthesis of all-Rp-oligo(ribonucleoside phosphorothioate)s. Nucleic Acids Res (1996) 0.75
Synthesis of diribonucleoside thiophosphates via stereospecific sulphurization of H-phosphonates. Nucleic Acids Symp Ser (1991) 0.75
The case for configurational stability of H-phosphonate diesters in the presence of diazabicyclo[5.4.0]undec-7-ene (DBU). Bioorg Med Chem (2001) 0.75
The human preproinsulin gene: synthesis, cloning, gene modification, and expression studies. Can J Biochem Cell Biol (1984) 0.75
A molecular dynamics computer simulation study of nucleotide analogues. Comparison of the hydration pattern of dithymidine phosphate with those of the dithymidine methylphosphonate diastereomers. J Biomol Struct Dyn (1998) 0.75
Synthesis of a human insulin gene. VII. Synthesis of preproinsulin-like human DNA, its cloning and expression in M13 bacteriophage. Gene (1984) 0.75
Synthesis and in vitro antiviral activity of some symmetrical phosphoramidate dimers of AZT. Nucleosides Nucleotides (1999) 0.75