Nanotechnology in medicine and the biosciences. The UK National Symposium on Nanotechnology in Medicine and the Biosciences, London, UK, 16-18 March l994.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 7765353)

Published in Trends Biotechnol on August 01, 1994

Authors

J Murphy1, B Carr, T Atkinson

Author Affiliations

1: Centre for Applied Microbiology and Research, Salisbury, Wilts., UK.

Articles by these authors

(truncated to the top 100)

Hepatic resection versus transplantation for hepatocellular carcinoma. Ann Surg (1991) 3.57

SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast. Mol Cell Biol (1999) 3.18

Characterization of a short, cis-acting DNA sequence which conveys cell cycle stage-dependent transcription in Saccharomyces cerevisiae. Mol Cell Biol (1991) 2.91

A specific, highly active malate dehydrogenase by redesign of a lactate dehydrogenase framework. Science (1988) 2.63

Bcl-2 phosphorylation required for anti-apoptosis function. J Biol Chem (1997) 2.47

A specific endonuclease from Bacillus caldolyticus. Nucleic Acids Res (1978) 2.18

Identification of functional regions in the transforming protein of Fujinami sarcoma virus by in-phase insertion mutagenesis. Cell (1984) 2.12

Design and synthesis of new enzymes based on the lactate dehydrogenase framework. Philos Trans R Soc Lond B Biol Sci (1991) 2.02

Resisting and promoting new technologies in clinical practice: the case of telepsychiatry. Soc Sci Med (2001) 1.84

Resuscitation skills of trainee anaesthetists. Anaesthesia (1995) 1.82

Binding and hydrolysis of nucleotides in the chaperonin catalytic cycle: implications for the mechanism of assisted protein folding. Biochemistry (1993) 1.78

The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene. Eur J Biochem (1990) 1.78

Cloning, expression and complete nucleotide sequence of the Bacillus stearothermophilus L-lactate dehydrogenase gene. Gene (1986) 1.76

Molecular evolution of bacterial cell-surface proteins. Trends Biochem Sci (1993) 1.72

Accelerated growth rates of recurrent hepatocellular carcinoma after liver transplantation. Cancer (1991) 1.68

Tramadol and severe serotonin syndrome. Anaesthesia (2005) 1.64

The complete nucleotide sequence of the Pseudomonas gene coding for carboxypeptidase G2. Gene (1984) 1.57

Molecular cloning of the Pseudomonas carboxypeptidase G2 gene and its expression in Escherichia coli and Pseudomonas putida. J Bacteriol (1983) 1.54

A prospective randomized study of pregnancy rates following intrauterine and intracervical insemination using frozen donor sperm. Fertil Steril (1990) 1.47

Molecular cloning of the Clostridium botulinum structural gene encoding the type B neurotoxin and determination of its entire nucleotide sequence. Appl Environ Microbiol (1992) 1.47

Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases. Proc Natl Acad Sci U S A (2000) 1.46

Site-directed mutagenesis reveals role of mobile arginine residue in lactate dehydrogenase catalysis. Nature (1987) 1.43

Hepatocellular carcinoma: evaluation with biphasic, contrast-enhanced, helical CT. Radiology (1996) 1.42

The purification of restriction endonuclease EcoRI by precipitation involving polyethyleneimine. FEBS Lett (1977) 1.42

Metabolic engineering of Geobacillus thermoglucosidasius for high yield ethanol production. Metab Eng (2009) 1.41

Deficient 17beta-hydroxysteroid dehydrogenase type 2 expression in endometriosis: failure to metabolize 17beta-estradiol. J Clin Endocrinol Metab (1998) 1.38

Enterococcal superinfection and colonization with aztreonam therapy. Antimicrob Agents Chemother (1984) 1.35

Reversible phosphorylation of Bcl2 following interleukin 3 or bryostatin 1 is mediated by direct interaction with protein phosphatase 2A. J Biol Chem (1998) 1.33

Liver transplantation for hepatocellular carcinoma: a proposal of a prognostic scoring system. J Am Coll Surg (2000) 1.33

Nucleotide sequence of the Erwinia chrysanthemi NCPPB 1066 L-asparaginase gene. Gene (1986) 1.31

The complete amino acid sequence of the Clostridium botulinum type-E neurotoxin, derived by nucleotide-sequence analysis of the encoding gene. Eur J Biochem (1992) 1.30

Heparin-binding growth factor type 1 (acidic fibroblast growth factor): a potential biphasic autocrine and paracrine regulator of hepatocyte regeneration. Proc Natl Acad Sci U S A (1989) 1.29

Cell proliferation and oncogene expression after bile duct ligation in the rat: evidence of a specific growth effect on bile duct cells. Hepatology (1995) 1.27

Liver transplantation for hepatocellular carcinoma. World J Surg (1995) 1.26

An investigation of the contribution made by the carboxylate group of an active site histidine-aspartate couple to binding and catalysis in lactate dehydrogenase. Biochemistry (1988) 1.25

Triazine-dye affinity; chromatography. Biochem Soc Trans (1981) 1.24

Co-expression and regulation of Met and Ron proto-oncogenes in human hepatocellular carcinoma tissues and cell lines. Hepatology (1997) 1.18

The use of genetically engineered tryptophan to identify the movement of a domain of B. stearothermophilus lactate dehydrogenase with the process which limits the steady-state turnover of the enzyme. Biochem Biophys Res Commun (1988) 1.18

A new rapid procedure for the preparation of plasmid DNA. Anal Biochem (1986) 1.17

Lactic acidosis associated with metastatic breast carcinoma. Cancer Treat Rep (1980) 1.15

Isolation and partial characterization of four plasmids from antibiotic-resistant thermophilic bacilli. J Gen Microbiol (1979) 1.11

The energetics and cooperativity of protein folding: a simple experimental analysis based upon the solvation of internal residues. Biochemistry (1993) 1.08

From analysis to synthesis: new ligand binding sites on the lactate dehydrogenase framework. Part II. Trends Biochem Sci (1989) 1.06

A strong carboxylate-arginine interaction is important in substrate orientation and recognition in lactate dehydrogenase. Biochim Biophys Acta (1987) 1.05

The replication proteins of plasmids pE194 and pLS1 have N-terminal homology. Nucleic Acids Res (1988) 1.05

Affinity of chaperonin-60 for a protein substrate and its modulation by nucleotides and chaperonin-10. Biochem J (1994) 1.05

Cloning and complete nucleotide sequence of the Bacillus stearothermophilus tryptophanyl tRNA synthetase gene. Gene (1986) 1.04

Transient NMDA receptor inactivation provides long-term protection to cultured cortical neurons from a variety of death signals. J Neurosci (2000) 1.04

Liver transplantation and chemotherapy for hepatoblastoma and hepatocellular cancer in childhood and adolescence. J Pediatr (2000) 1.04

Sequential 1H NMR assignments and secondary structure of an IgG-binding domain from protein G. Biochemistry (1991) 1.03

From analysis to synthesis: new ligand binding sites on the lactate dehydrogenase framework. Part I. Trends Biochem Sci (1989) 1.03

Nucleotide sequence analysis of the gene for protein A from Staphylococcus aureus Cowan 1 (NCTC8530) and its enhanced expression in Escherichia coli. Gene (1987) 1.03

The influence of changes in tension on protein synthesis and prostaglandin release in isolated rabbit muscles. Biochem J (1983) 1.03

Affinity labelling of enzymes with triazine dyes. Isolation of a peptide in the catalytic domain of horse-liver alcohol dehydrogenase using Procion blue MX-R as a structural probe. Eur J Biochem (1982) 1.01

The stability and hydrophobicity of cytosolic and mitochondrial malate dehydrogenases and their relation to chaperonin-assisted folding. FEBS Lett (1994) 1.01

The social costs of unemployment: implications for social support. J Health Soc Behav (1986) 1.00

Designs for a broad substrate specificity keto acid dehydrogenase. Biochemistry (1990) 1.00

Characterization of Bacillus stearothermophilus plasmid pab124 and construction of deletion variants. J Gen Microbiol (1980) 1.00

Nucleotide sequence of the thymidylate synthetase gene (thyP3) from the Bacillus subtilis phage phi 3T. Gene (1985) 1.00

The importance of arginine 102 for the substrate specificity of Escherichia coli malate dehydrogenase. Biochem Biophys Res Commun (1992) 0.98

Detection and characterization of intermediates in the folding of large proteins by the use of genetically inserted tryptophan probes. Biochemistry (1991) 0.97

Hepatocellular carcinoma: the role of helical biphasic contrast-enhanced CT versus CT during arterial portography. Radiology (1997) 0.97

Cloning and overexpression of Lactobacillus helveticus D-lactate dehydrogenase gene in Escherichia coli. Eur J Biochem (1992) 0.97

Expression in Escherichia coli of a synthetic gene coding for horse heart myoglobin. Protein Eng (1991) 0.96

The effect of lactation length on the circulating concentrations of progesterone and oestradiol in the early weaned sow. Theriogenology (1981) 0.95

Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy. J Clin Oncol (1990) 0.95

The 11-year Pittsburgh experience with liver transplantation for hepatocellular carcinoma: 1981-1991. J Surg Oncol Suppl (1993) 0.95

Isolation and characterisation of the glycerol dehydrogenase from Bacillus stearothermophilus. Biochim Biophys Acta (1989) 0.94

The clinical application of the Malone antegrade colonic enema. J Pediatr Surg (1993) 0.94

Enhanced plasma persistence of therapeutic enzymes by coupling to soluble dextran. Biochem J (1977) 0.93

Cloning and nucleotide sequences of the mdh and sucD genes from Thermus aquaticus B. FEMS Microbiol Lett (1990) 0.92

Long-term (> 3-year) insulin independence in a patient with pancreatic islet cell transplantation following upper abdominal exenteration and liver replacement for fibrolamellar hepatocellular carcinoma. Transplantation (1995) 0.91

The purification and characterization of glucokinase from the thermophile Bacillus stearothermophilus. Biochem J (1986) 0.90

A single amino acid substitution deregulates a bacterial lactate dehydrogenase and stabilizes its tetrameric structure. Biochim Biophys Acta (1987) 0.90

Thrombocytosis in intensive care. Br J Anaesth (2001) 0.90

Erwinia chrysanthemi L-asparaginase: epitope mapping and production of antigenically modified enzymes. Biochem J (1994) 0.90

Hepatocellular carcinomas in native livers from patients treated with orthotopic liver transplantation: biologic and therapeutic implications. Hepatology (2001) 0.90

An outbreak of avian malaria in captive yellowheads/mohua (Mohoua ochrocephala). N Z Vet J (2008) 0.89

Hypothalamic NPY and prepro-NPY mRNA in Djungarian hamsters: effects of food deprivation and photoperiod. Am J Physiol (1995) 0.88

The application of triazine dye affinity chromatography to the large-scale purification of glycerokinase from Bacillus stearothermophilus. Anal Biochem (1983) 0.88

Cloning, expression and purification of Ppl-1, a kappa-chain binding protein, based upon protein L from Peptostreptococcus magnus. Bioseparation (1995) 0.87

The binding of aminoacyl-tRNA synthetases to triazine dye conjugates. Nucleic Acids Res (1979) 0.87

The rapid purification of 3-hydroxybutyrate dehydrogenase and malate dehydrogenase on triazine dye affinity matrices. Biochem J (1982) 0.87

The functional units of a peptostreptococcal protein L. Mol Microbiol (1994) 0.86

Expression and purification of a truncated recombinant streptococcal protein G. Biochem J (1990) 0.86

The importance of arginine 171 in substrate binding by Bacillus stearothermophilus lactate dehydrogenase. Biochem Biophys Res Commun (1987) 0.86

Clinicopathologic factors affecting patient survival and tumor recurrence after orthotopic liver transplantation for hepatocellular carcinoma. Transplant Proc (1991) 0.86

Isolation of thrombin inhibitor from the leech Hirudinaria manillensis. Blood Coagul Fibrinolysis (1991) 0.86

Amino acid sequence of the L-lactate dehydrogenase of Bacillus caldotenax deduced from the nucleotide sequence of the cloned gene. Eur J Biochem (1987) 0.85

The isolation and characterization of bacteriophages infecting obligately thermophilic strains of Bacillus. J Gen Microbiol (1986) 0.85

Specific glucocorticoid inhibition of growth promoting effects of prostaglandin F2alpha on 3T3 cells. Nature (1977) 0.85

Dopamine-beta-hydroxylase deficiency in humans. Neurology (1990) 0.85

Molecular cloning and nucleotide sequence determination of the Bacillus stearothermophilus NCA 1503 superoxide dismutase gene and its overexpression in Escherichia coli. Appl Microbiol Biotechnol (1991) 0.85

The engineering of a more thermally stable lactate dehydrogenase by reduction of the area of a water-accessible hydrophobic surface. Biochim Biophys Acta (1987) 0.84

Comparative clinical evaluation of mezlocillin and cefoxitin. J Antimicrob Chemother (1982) 0.84

Restriction endonucleases and modification methylases in bacteria. Biochem Soc Trans (1978) 0.84

The interaction of tryptophanyl-tRNA synthetase with the triazine dye Brown MX-5BR. Eur J Biochem (1982) 0.84

The effects of FK 506, cyclosporine, and rapamycin on liver growth in vitro and in vivo. Transplant Proc (1991) 0.84

Abnormal prothrombin (DES-gamma-carboxy prothrombin) in hepatocellular carcinoma. Hepatogastroenterology (1991) 0.84

Rational construction of a 2-hydroxyacid dehydrogenase with new substrate specificity. Biochem Biophys Res Commun (1987) 0.83