Published in J Virol on July 01, 1995
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Nef enhances HIV-1 infectivity via association with the virus assembly complex. Virology (2008) 1.01
Myristoyl moiety of HIV Nef is involved in regulation of the interaction with calmodulin in vivo. Protein Sci (2005) 0.98
Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41. PLoS Pathog (2011) 0.98
Simian immunodeficiency virus containing mutations in N-terminal tyrosine residues and in the PxxP motif in Nef replicates efficiently in rhesus macaques. J Virol (2000) 0.96
Induction of phosphorylation of human immunodeficiency virus type 1 Nef and enhancement of CD4 downregulation by phorbol myristate acetate. J Virol (1997) 0.95
Nef enhances human immunodeficiency virus type 1 infectivity in the absence of matrix. J Virol (2002) 0.93
Importance of the N-distal AP-2 binding element in Nef for simian immunodeficiency virus replication and pathogenicity in rhesus macaques. J Virol (2006) 0.92
HIV-1 Nef responsiveness is determined by Env variable regions involved in trimer association and correlates with neutralization sensitivity. Cell Rep (2013) 0.92
Simian immunodeficiency virus and human immunodeficiency virus type 1 nef proteins show distinct patterns and mechanisms of Src kinase activation. J Virol (1999) 0.90
The activity of Nef on HIV-1 infectivity. Front Microbiol (2014) 0.90
Infectivity enhancement by human immunodeficiency virus type 1 Nef is independent of its association with a cellular serine/threonine kinase. J Virol (1997) 0.90
The Nef-like effect of murine leukemia virus glycosylated gag on HIV-1 infectivity is mediated by its cytoplasmic domain and depends on the AP-2 adaptor complex. J Virol (2014) 0.90
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Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function. Retrovirology (2012) 0.87
Nef-induced CD4 endocytosis in human immunodeficiency virus type 1 host cells: role of p56lck kinase. J Virol (2009) 0.87
In vivo analysis of highly conserved Nef activities in HIV-1 replication and pathogenesis. Retrovirology (2013) 0.86
Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix. Retrovirology (2012) 0.85
Conformational transition of membrane-associated terminally acylated HIV-1 Nef. Structure (2013) 0.84
Neutron reflectometry study of the conformation of HIV Nef bound to lipid membranes. Biophys J (2010) 0.83
The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement. PLoS One (2011) 0.83
Heterologous Src homology 4 domains support membrane anchoring and biological activity of HIV-1 Nef. J Biol Chem (2014) 0.80
Transcription of preintegrated HIV-1 cDNA modulates cell surface expression of major histocompatibility complex class I via Nef. J Virol (2011) 0.80
Human immunodeficiency virus type 1 Nef does not alter T-cell sensitivity to antigen-specific stimulation. J Virol (1997) 0.78
Interactions between SIVNef, SIVGagPol and Alix correlate with viral replication and progression to AIDS in rhesus macaques. Virology (2009) 0.78
Recent Insights into HIV Accessory Proteins. Curr Infect Dis Rep (2003) 0.78
Impacts of humanized mouse models on the investigation of HIV-1 infection: illuminating the roles of viral accessory proteins in vivo. Viruses (2015) 0.78
HIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenon. Viruses (2013) 0.77
HIV-1 Nef inhibits Protease activity and its absence alters protein content of mature viral particles. PLoS One (2014) 0.76
Down-modulation of primate lentiviral receptors by Nef proteins of simian immunodeficiency virus (SIV) of chimpanzees (SIVcpz) and related SIVs: implication for the evolutionary event at the emergence of SIVcpz. J Gen Virol (2015) 0.76
A Truncated Nef Peptide from SIVcpz Inhibits the Production of HIV-1 Infectious Progeny. Viruses (2016) 0.75
Identification of SERINC5-001 as the Predominant Spliced Isoform for HIV-1 Restriction. J Virol (2017) 0.75
Clearly different mechanisms of enhancement of short-lived Nef-mediated viral infectivity between SIV and HIV-1. Virol J (2014) 0.75
Myristoylation: An Important Protein Modification in the Immune Response. Front Immunol (2017) 0.75
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