Androgens induce resistance to bcl-2-mediated apoptosis in LNCaP prostate cancer cells.

PubWeight™: 1.07‹?› | Rank: Top 10%

🔗 View Article (PMID 7850782)

Published in Cancer Res on February 15, 1995

Authors

G J Berchem1, M Bosseler, L Y Sugars, H J Voeller, S Zeitlin, E P Gelmann

Author Affiliations

1: Department of Medicine, Lombardi Cancer Center, Georgetown University School of Medicine, Washington, DC 20007.

Associated clinical trials:

Docetaxel, Thalidomide, Prednisone, and Bevacizumab to Treat Metastatic Prostate Cancer | NCT00089609

Articles citing this

Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers. Am J Pathol (1996) 2.97

A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy. Cell Death Dis (2010) 1.87

Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells. Proc Natl Acad Sci U S A (1998) 1.74

Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells. Mol Cell Biol (2004) 1.07

Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition. Evid Based Complement Alternat Med (2012) 1.04

Broad targeting of resistance to apoptosis in cancer. Semin Cancer Biol (2015) 1.03

Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions. Br J Cancer (2001) 0.86

D-RNAi (messenger RNA-antisense DNA interference) as a novel defense system against cancer and viral infections. Curr Cancer Drug Targets (2001) 0.85

Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance. Nucleic Acids Res (2012) 0.85

Role of the Bcl-2 gene family in prostate cancer progression and its implications for therapeutic intervention. Environ Health Perspect (1999) 0.83

Growth inhibition of DU-145 prostate cancer cells by a Bcl-2 antisense oligonucleotide is enhanced by N-(2-hydroxyphenyl)all-trans retinamide. Br J Cancer (1998) 0.80

The role of intracrine androgen metabolism, androgen receptor and apoptosis in the survival and recurrence of prostate cancer during androgen deprivation therapy. Curr Drug Targets (2013) 0.80

To die or to survive, a fatal question for the destiny of prostate cancer cells after androgen deprivation therapy. Cancers (Basel) (2011) 0.78

Prostate Cancer - Old Problems and New Approaches. (Part II. Diagnostic and Prognostic Markers, Pathology and Biological Aspects). Pathol Oncol Res (1996) 0.76

Neuroendocrine prostate cancer (NEPCa) increased the neighboring PCa chemoresistance via altering the PTHrP/p38/Hsp27/androgen receptor (AR)/p21 signals. Oncogene (2016) 0.75

Articles by these authors

Design of the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. Control Clin Trials (2000) 10.99

NIH conference. Acquired immunodeficiency syndrome: epidemiologic, clinical, immunologic, and therapeutic considerations. Ann Intern Med (1984) 6.45

Expression of cellular homologues of retroviral onc genes in human hematopoietic cells. Proc Natl Acad Sci U S A (1982) 5.80

Isolation of human T-cell leukemia virus in acquired immune deficiency syndrome (AIDS). Science (1983) 4.72

Cloning and characterization of different human sequences related to the onc gene (v-myc) of avian myelocytomatosis virus (MC29). Proc Natl Acad Sci U S A (1982) 4.70

Cryptococcosis in the acquired immunodeficiency syndrome. Ann Intern Med (1985) 4.25

In vivo splicing products of the rabbit beta-globin pre-mRNA. Cell (1984) 3.35

Physical properties of membrane lipids: biological relevance and regulation. Bacteriol Rev (1975) 3.18

Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice. Nat Genet (2000) 2.95

NIH conference. The acquired immunodeficiency syndrome: an update. Ann Intern Med (1985) 2.68

A novel human prostate-specific, androgen-regulated homeobox gene (NKX3.1) that maps to 8p21, a region frequently deleted in prostate cancer. Genomics (1997) 2.65

Beta-catenin affects androgen receptor transcriptional activity and ligand specificity. Cancer Res (2000) 2.44

Beta-catenin mutations in human prostate cancer. Cancer Res (1998) 2.37

RNA-mediated gene duplication: the rat preproinsulin I gene is a functional retroposon. Mol Cell Biol (1985) 2.35

A survey of human leukaemias for sequences of a human retrovirus. Nature (1983) 2.27

Pre-mRNA splicing and the nuclear matrix. Mol Cell Biol (1987) 2.22

Correlation between immunologic function and clinical subpopulations of patients with the acquired immune deficiency syndrome. Am J Med (1985) 2.18

Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression. Cancer Res (2000) 2.13

Differentiation state and invasiveness of human breast cancer cell lines. Breast Cancer Res Treat (1994) 2.05

CaMKIIalpha-Cre transgene expression and recombination patterns in the mouse brain. Genesis (2000) 2.04

A human onc gene homologous to the transforming gene (v-sis) of simian sarcoma virus. Nature (1981) 1.94

Human ADP-ribosylation factors. A functionally conserved family of GTP-binding proteins. J Biol Chem (1991) 1.89

Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice. Neuroscience (2008) 1.76

Epidermal growth factor receptor gene expression in estrogen receptor-positive and negative human breast cancer cell lines. Mol Endocrinol (1987) 1.72

Rat insulin-like growth factor II gene. A single gene with two promoters expressing a multitranscript family. J Mol Biol (1986) 1.72

Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes. Mamm Genome (2000) 1.71

p53 oncogene mutations in three human prostate cancer cell lines. Prostate (1993) 1.70

Mutant of Escherichia coli deficient in the synthesis of cis-vaccenic acid. J Bacteriol (1972) 1.61

Isolation of HTLV-transformed B-lymphocyte clone from a patient with HTLV-associated adult T-cell leukaemia. Nature (1984) 1.58

Homology of human T-cell leukaemia virus envelope gene with class I HLA gene. Nature (1983) 1.58

Molecular cloning and comparative analyses of the genomes of simian sarcoma virus and its associated helper virus. Proc Natl Acad Sci U S A (1981) 1.57

Does tamoxifen cause cancer in humans? J Clin Oncol (1998) 1.50

Vimentin rather than keratin expression in some hormone-independent breast cancer cell lines and in oncogene-transformed mammary epithelial cells. Cancer Res (1989) 1.49

Identification of reciprocal translocation sites within the c-myc oncogene and immunoglobulin mu locus in a Burkitt lymphoma. Nature (1984) 1.49

Cell adhesion molecule uvomorulin expression in human breast cancer cell lines: relationship to morphology and invasive capacities. Cell Growth Differ (1991) 1.49

Proviral DNA of a retrovirus, human T-cell leukemia virus, in two patients with AIDS. Science (1983) 1.49

Minimal exon sequence requirements for efficient in vitro splicing of mono-intronic nuclear pre-mRNA. J Biol Chem (1987) 1.48

Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease. J Neurosci Res (1999) 1.48

Alterations in beta-catenin phosphorylation and plakoglobin expression in human breast cancer cells. Cancer Res (1994) 1.43

Human T-cell leukemia-lymphoma virus (HTLV): cloning of an integrated defective provirus and flanking cellular sequences. Proc Natl Acad Sci U S A (1983) 1.38

Malignant pheochromocytoma: effective treatment with a combination of cyclophosphamide, vincristine, and dacarbazine. Ann Intern Med (1988) 1.37

Null mutation of the murine ATP7B (Wilson disease) gene results in intracellular copper accumulation and late-onset hepatic nodular transformation. Hum Mol Genet (1999) 1.36

Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues. Development (1998) 1.35

Loss of epithelial markers and acquisition of vimentin expression in adriamycin- and vinblastine-resistant human breast cancer cell lines. Cancer Res (1992) 1.35

Molecular cloning of a unique human T-cell leukemia virus (HTLV-IIMo). Proc Natl Acad Sci U S A (1984) 1.32

An estimate of the minimum amount of unsaturated fatty acid required for growth of Escherichia coli. J Biol Chem (1973) 1.31

Three distinct genes in human DNA related to the transforming genes of mammalian sarcoma retroviruses. Science (1981) 1.26

Transfection of v-rasH DNA into MCF-7 human breast cancer cells bypasses dependence on estrogen for tumorigenicity. Science (1985) 1.26

Deletions of specific regions of the simian sarcoma-associated virus genome are found in defective viruses and in the simian sarcoma virus. J Virol (1982) 1.25

Guinea pig preproinsulin gene: an evolutionary compromise? Proc Natl Acad Sci U S A (1984) 1.24

Coding region of NKX3.1, a prostate-specific homeobox gene on 8p21, is not mutated in human prostate cancers. Cancer Res (1997) 1.24

Activation of growth factor secretion in tumorigenic states of breast cancer induced by 17 beta-estradiol or v-Ha-ras oncogene. Proc Natl Acad Sci U S A (1987) 1.22

Hepatitis B virus infection in the acquired immunodeficiency syndrome. Ann Intern Med (1984) 1.22

Aberrant response in vitro of hormone-responsive prostate cancer cells to antiandrogens. Prostate (1989) 1.19

A point mutation in the c-myc locus of a Burkitt lymphoma abolishes binding of a nuclear protein. Science (1988) 1.16

Structural analysis of inhibitor binding to human carbonic anhydrase II. Protein Sci (1998) 1.16

Salmonella typhimurium enteritis and bacteremia in the acquired immunodeficiency syndrome. Ann Intern Med (1985) 1.15

5' viral and human cellular sequences corresponding to the transforming gene of simian sarcoma virus. Science (1983) 1.14

Resistance to apoptosis and up regulation of Bcl-2 in benign prostatic hyperplasia after androgen deprivation. J Urol (1997) 1.12

The v-sis transforming gene of simian sarcoma virus is a new onc gene of primate origin. Nature (1981) 1.11

Decrease in striatal enkephalin mRNA in mouse models of Huntington's disease. Exp Neurol (2000) 1.11

8th San Antonio Breast Cancer Symposium--Plenary lecture. Autocrine and paracrine growth regulation of human breast cancer. Breast Cancer Res Treat (1986) 1.11

Distinct signals are required for proliferation and lymphokine gene expression in murine T cell clones. J Immunol (1986) 1.11

Molecular cloning of circular unintegrated DNA of two types of the SEATO strain of gibbon ape leukemia virus. J Virol (1982) 1.11

DNA-binding sequence of the human prostate-specific homeodomain protein NKX3.1. Nucleic Acids Res (2000) 1.11

Sphingosine enhances apoptosis of radiation-resistant prostate cancer cells. Cancer Res (2000) 1.09

Avian fracture healing. J Am Vet Med Assoc (1977) 1.07

erbB-2 antisense oligonucleotides inhibit the proliferation of breast carcinoma cells with erbB-2 oncogene amplification. Br J Cancer (1994) 1.07

Differential non-responsiveness in humans of candidate Plasmodium falciparum vaccine antigens. Am J Trop Med Hyg (1989) 1.05

Sera from patients with the acquired immunodeficiency syndrome inhibit production of interleukin-2 by normal lymphocytes. J Clin Invest (1985) 1.04

Oligoclonal immunoglobulins in patients with the acquired immunodeficiency syndrome. Clin Immunol Immunopathol (1985) 1.02

A method for the generation of conditional gene repair mutations in mice. Nucleic Acids Res (2001) 0.99

Tumor necrosis factor-alpha sensitizes prostate cancer cells to gamma-irradiation-induced apoptosis. Cancer Res (1999) 0.98

p53 oncogene mutations in human prostate cancer specimens. J Urol (1994) 0.98

Neurons lacking huntingtin differentially colonize brain and survive in chimeric mice. J Neurosci (2001) 0.98

Tamoxifen induction of apoptosis in estrogen receptor-negative cancers: new tricks for an old dog? J Natl Cancer Inst (1996) 0.97

Growth regulation of human breast carcinoma occurs through regulated growth factor secretion. J Cell Biochem (1987) 0.96

Androgen blocks apoptosis of hormone-dependent prostate cancer cells. Cancer Res (2001) 0.95

Combination chemotherapy of disseminated Kaposi's sarcoma in patients with the acquired immune deficiency syndrome. Am J Med (1987) 0.94

Radiation-induced apoptosis mediated by retinoblastoma protein. Cancer Res (1998) 0.94

Role of transforming growth factor-alpha in human prostate cancer cell growth. Prostate (1989) 0.93

Heterogeneous expression of erbB-2 messenger RNA in human breast cancer. Cancer Res (1989) 0.93

v-rasH expression confers hormone-independent in vitro growth to LNCaP prostate carcinoma cells. Mol Endocrinol (1991) 0.93

Expression of the Huntingtin-associated protein 1 gene in the developing and adult mouse. Neurosci Lett (2000) 0.92

Growth properties and tumorigenesis of MCF-7 cells transfected with isogenic mutants of rasH. Cancer Res (1990) 0.92

Interferon-induced 2'-5' oligoadenylate synthetase during interferon-alpha therapy in homosexual men with Kaposi's sarcoma: marked deficiency in biochemical response to interferon in patients with acquired immunodeficiency syndrome. J Infect Dis (1985) 0.92

Human lymphoblastoid interferon treatment of Kaposi's sarcoma in the acquired immune deficiency syndrome. Clinical response and prognostic parameters. Am J Med (1985) 0.91

Human gene (c-fes) related to the onc sequences of Snyder-Theilen feline sarcoma virus. Mol Cell Biol (1982) 0.91

A hemolytic-uremic syndrome with the acquired immunodeficiency syndrome. Ann Intern Med (1984) 0.91

p53 abnormalities in primary prostate cancer: single-strand conformation polymorphism analysis of complementary DNA in comparison with genomic DNA. The Cooperative Prostate Network. J Natl Cancer Inst (1997) 0.91

Use of interleukin-2 in patients with acquired immunodeficiency syndrome. J Biol Response Mod (1984) 0.90

Role of interferon in AIDS. Ann N Y Acad Sci (1984) 0.88

Effects of steroid hormones and peptide growth factors on protooncogene c-fos expression in human breast cancer cells. Cancer Res (1988) 0.87

Nanomolar range docetaxel treatment sensitizes MCF-7 cells to chemotherapy induced apoptosis, induces G2M arrest and phosphorylates bcl-2. Anticancer Res (1999) 0.86

Use of two MCF-7 cell variants to evaluate the growth regulatory potential of estrogen-induced products. Cancer Res (1986) 0.86

RB status as a determinant of response to UCN-01 in non-small cell lung carcinoma. Clin Cancer Res (1999) 0.85