Published in Eur J Biochem on February 15, 1995
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Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain. Proc Natl Acad Sci U S A (1992) 2.59
Dietary salt restriction and reduction of dialysate sodium to control hypertension in maintenance haemodialysis patients. Nephrol Dial Transplant (1998) 2.15
Cloning and characterization of the mammalian brain-specific, Mg2+-dependent neutral sphingomyelinase. Proc Natl Acad Sci U S A (2000) 1.88
Early events leading to renal injury in obese Zucker (fatty) rats with type II diabetes. Kidney Int (2000) 1.79
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Biochemical analysis of the pinocytotic process. I. Isolation and chemical composition of the lysosomal and the plasma membrane of the rat liver cell. Hoppe Seylers Z Physiol Chem (1970) 1.56
Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration. EMBO J (1997) 1.54
Individual exons encode the integral membrane domains of human myelin proteolipid protein. Proc Natl Acad Sci U S A (1986) 1.50
Assembly of myelin by association of proteolipid protein with cholesterol- and galactosylceramide-rich membrane domains. J Cell Biol (2000) 1.47
Novel approach to specific growth factor inhibition in vivo: antagonism of platelet-derived growth factor in glomerulonephritis by aptamers. Am J Pathol (1999) 1.42
Functional breakdown of the lipid bilayer of the myelin membrane in central and peripheral nervous system by disrupted galactocerebroside synthesis. Proc Natl Acad Sci U S A (1996) 1.41
Acid sphingomyelinase-deficient mice mimic the neurovisceral form of human lysosomal storage disease (Niemann-Pick disease). Cell (1995) 1.39
Biosynthesis and composition of phosphatides in outer and inner mitochondrial membranes. Hoppe Seylers Z Physiol Chem (1968) 1.38
Possible interaction of fluoroquinolones with the benzodiazepine-GABAA-receptor complex. Br J Clin Pharmacol (1990) 1.35
Proteolipid protein (PLP) of CNS myelin: positions of free, disulfide-bonded, and fatty acid thioester-linked cysteine residues and implications for the membrane topology of PLP. Biochemistry (1992) 1.31
Studies on the occurrence and properties of lysosomal phospholipases A1 and A2 and the degradation of phosphatidic acid in rat liver lysosomes. Hoppe Seylers Z Physiol Chem (1969) 1.29
The primary structure of bovine brain myelin lipophilin (proteolipid apoprotein). Hoppe Seylers Z Physiol Chem (1983) 1.24
Structure and molecular arrangement of proteolipid protein of central nervous system myelin. Proc Natl Acad Sci U S A (1984) 1.22
PROFILEGRAPH: an interactive graphical tool for protein sequence analysis. Comput Appl Biosci (1992) 1.22
Characterization and subcellular localization of murine and human magnesium-dependent neutral sphingomyelinase. J Biol Chem (2000) 1.21
Chemical synthesis of choline-labeled lecithins and sphingomyelins. Methods Enzymol (1975) 1.19
Disruption of the compacted myelin sheath of axons of the central nervous system in proteolipid protein-deficient mice. Proc Natl Acad Sci U S A (1994) 1.18
Application of specific extracorporeal removal of low density lipoprotein in familial hypercholesterolaemia. Lancet (1981) 1.13
Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis. Eur J Biochem (1997) 1.12
Early mechanisms of renal injury in hypercholesterolemic or hypertriglyceridemic rats. J Am Soc Nephrol (2000) 1.12
Biochemical analsis of the inocytotic process. II. Comparison of some enzymes of the lysosomal nd the plasma membrane of the rat liver cel. Hoppe Seylers Z Physiol Chem (1970) 1.11
Adhesive properties of proteolipid protein are responsible for the compaction of CNS myelin sheaths. J Neurosci (1995) 1.10
Lipids with photosensitive groups as chemical probes for the structural analysis of biological membranes. On the localization of the G- and M-protein of vesicular stomatitis virus. Hoppe Seylers Z Physiol Chem (1978) 1.07
Ceramide UDPgalactosyltransferase from myelinating rat brain: purification, cloning, and expression. Proc Natl Acad Sci U S A (1993) 1.06
Studies in vitro on the biosynthesis of ceramide and sphingomyelin. A reevaluation of proposed pathways. Hoppe Seylers Z Physiol Chem (1980) 1.03
Galactosphingolipids and axono-glial interaction in myelin of the central nervous system. Cell Tissue Res (1998) 1.02
13C-NMR studies of the membrane structure of enveloped virions (vesicular stomatitis virus). Hoppe Seylers Z Physiol Chem (1976) 1.01
Chemical proof of lipid-protein interactions by crosslinking photosensitive lipids to apoproteins. Intermolecular cross-linkage between high-density apolipoprotein A-I and lecithins and sphingomyelins. Hoppe Seylers Z Physiol Chem (1977) 1.01
A simple chemical method for labelling phosphatidylcholine and sphingomyelin in the choline moiety. Hoppe Seylers Z Physiol Chem (1971) 1.00
Glycosphingolipids in lysosomal membranes. Hoppe Seylers Z Physiol Chem (1973) 1.00
Studies on lipolytic activities of rat liver lysosomes. Hoppe Seylers Z Physiol Chem (1967) 1.00
Sphingolipid metabolism in Bacteroideaceae. Hoppe Seylers Z Physiol Chem (1975) 0.99
Inhibition of cholesterol synthesis in cultured cells by 25-azidonorcholesterol. Hoppe Seylers Z Physiol Chem (1978) 0.98
Tumor necrosis factor alpha activates NF-kappaB in acid sphingomyelinase-deficient mouse embryonic fibroblasts. J Biol Chem (1997) 0.98
Lipophilin (proteolipid apoprotein) of brain white matter. Purification and amino acid sequence studies of the four tryptophan fragments. Hoppe Seylers Z Physiol Chem (1982) 0.97
Localization of N-glycosylation sites and functional role of the carbohydrate units of GLAST-1, a cloned rat brain L-glutamate/L-aspartate transporter. Eur J Biochem (1995) 0.97
Functional analysis of the high affinity, Na(+)-dependent glutamate transporter GLAST-1 by site-directed mutagenesis. J Biol Chem (1995) 0.97
Membrane attack complex of complement: distribution of subunits between the hydrocarbon phase of target membranes and water. Proc Natl Acad Sci U S A (1981) 0.97
Studies on the biosynthesis and degradation of sphingosine bases. Chem Phys Lipids (1970) 0.96
A facile method for the isolation and preparation of proteins and peptides for sequence analysis in the picomolar range. Biol Chem Hoppe Seyler (1990) 0.96
[Metabolism of unsaturated fatty acids. V. On the beta-oxidation of mono- and polyene-fatty acids. Mechanism of enzymatic reactions of delta-2-cis-enoyl-CoA compounds]. Hoppe Seylers Z Physiol Chem (1965) 0.96
Synthesis in vitro and translocation of apolipoprotein AI across microsomal vesicles. Eur J Biochem (1981) 0.95
Human mitochondrial 3,2-trans-enoyl-CoA isomerase (DCI): gene structure and localization to chromosome 16p13.3. Genomics (1994) 0.95
Myelin structure in proteolipid protein (PLP)-null mouse spinal cord. J Comp Neurol (1996) 0.95
Nature and localization of acidic groups on lysosomal membranes. Biochim Biophys Acta (1973) 0.94
The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): cloning, characterization, and assignment to human chromosome 4, band q26. Genomics (1996) 0.94
Functional properties and substrate specificity of the cloned L-glutamate/L-aspartate transporter GLAST-1 from rat brain expressed in Xenopus oocytes. J Neurosci (1994) 0.94
Myelin-deficient rat: a point mutation in exon III (A----C, Thr75----Pro) of the myelin proteolipid protein causes dysmyelination and oligodendrocyte death. EMBO J (1989) 0.93
Monolayer studies with synthetic saturated, mono- and polyunsaturated mixed 1,2-diglycerides, 1,2-diacylphosphatidylethanolamines and phosphatidylcholines at the air-water-interface. Hoppe Seylers Z Physiol Chem (1969) 0.93
Properties and specificities of sphingosine kinase from blood platelets. Hoppe Seylers Z Physiol Chem (1975) 0.93
Progression of diabetic nephropathy. Insights from cell culture studies and animal models. Kidney Blood Press Res (1999) 0.92
Cloned proteolipid protein and myelin basic protein cDNA. Transcription of the two genes during myelination. Biol Chem Hoppe Seyler (1986) 0.92
Association of prolonged hyperglycemia with glomerular hypertrophy and renal basement membrane thickening in the Goto Kakizaki model of non-insulin-dependent diabetes mellitus. Am J Kidney Dis (2001) 0.92
Membrane topology of the high-affinity L-glutamate transporter (GLAST-1) of the central nervous system. J Cell Biol (1996) 0.90
Selective removal of apolipoprotein B-containing serum lipoproteins from blood plasma. Proc Natl Acad Sci U S A (1981) 0.90
Sphingosine kinase in blood platelets. Hoppe Seylers Z Physiol Chem (1973) 0.90
Metabolism of sphingosine bases. XV. Enzymatic degradation of 4t-sphingenine 1-phosphate (sphingosine 1-phosphate) to 2t-hexadecen-1-al and ethanolamine phosphate. Hoppe Seylers Z Physiol Chem (1970) 0.90
Electrogenic L-glutamate uptake in Xenopus laevis oocytes expressing a cloned rat brain L-glutamate/L-aspartate transporter (GLAST-1). J Biol Chem (1993) 0.90
Sphingosine metabolism and its link to phospholipid biosynthesis. Mol Cell Biochem (1973) 0.90
[The metabolism of unsaturated fatty acid. 3. On the beta-oxidation of mono- and polyene-fatty acids. The mechanism of the enzymatic reaction on delta-3-cis-enoyl-CoA compounds]. Hoppe Seylers Z Physiol Chem (1964) 0.89
Light and electron microscopic analysis of the central and peripheral nervous systems of acid sphingomyelinase-deficient mice resulting from gene targeting. J Neuropathol Exp Neurol (1997) 0.89
Cell-free translation of human liver apolipoprotein AI and AII mRNA. Processing of primary translation products. Hoppe Seylers Z Physiol Chem (1983) 0.89
Composition and biophysical properties of myelin lipid define the neurological defects in galactocerebroside- and sulfatide-deficient mice. J Neurochem (1998) 0.88
[A 52-year-old woman with acute shock and purpura fulminans. Pneumococcal sepsis]. Internist (Berl) (2008) 0.88
Ceramide-independent CD28 and TCR signaling but reduced IL-2 secretion in T cells of acid sphingomyelinase-deficient mice. Eur J Immunol (1998) 0.88
Stereospecificities in the metabolic reactions of the four isomeric sphinganines (dihydrosphingosines) in rat liver. Hoppe Seylers Z Physiol Chem (1973) 0.88
Inhibition of the high-affinity brain glutamate transporter GLAST-1 via direct phosphorylation. J Neurochem (1997) 0.88
The metabolism of sphingosine bases in Tetrahymena pyriformis. Sphingosine kinase and sphingosine-1-phosphate lyase. Hoppe Seylers Z Physiol Chem (1974) 0.87
Biosynthetic incorporation of fatty acids with photosensitive groups into membrane lipids of cells in tissue culture. Hoppe Seylers Z Physiol Chem (1976) 0.87
Site-directed mutagenesis of putative active-site amino acid residues of 3,2-trans-enoyl-CoA isomerase, conserved within the low-homology isomerase/hydratase enzyme family. Biochemistry (1993) 0.87
Mitochondrial 3-2trans-Enoyl-CoA isomerase. Purification, cloning, expression, and mitochondrial import of the key enzyme of unsaturated fatty acid beta-oxidation. Biol Chem Hoppe Seyler (1991) 0.87
Incorporation of complete phospholipid molecules in cellular membranes of rat liver after uptake from blood serum. Hoppe Seylers Z Physiol Chem (1972) 0.87
Decompaction of CNS myelin leads to a reduction of the conduction velocity of action potentials in optic nerve. Neurosci Lett (1995) 0.87
Enzymatic studies on the mechanism of the retroconversion of C22-polyenoic fatty acids to their C20-homologues. Hoppe Seylers Z Physiol Chem (1970) 0.86
13C nuclear magnetic resonance spectroscopic evidence for hydrophobic lipid-protein interactions in human high density lipoproteins. Proc Natl Acad Sci U S A (1974) 0.86
The representation of inflectional morphology: evidence from Broca's aphasia. Brain Lang (1999) 0.86
UDP galactose:ceramide galactosyltransferase and glutamate/aspartate transporter. Copurification, separation and characterization of the two glycoproteins. Eur J Biochem (1995) 0.86
Evolution of the myelin integral membrane proteins of the central nervous system. Biol Chem Hoppe Seyler (1991) 0.86
Purification and properties of 3-cis-2-trans-enoyl-CoA isomerase (dodecenoyl-CoA delta-isomerase) from rat liver mitochondria. Hoppe Seylers Z Physiol Chem (1978) 0.86
Sphingolipids. Annu Rev Biochem (1971) 0.85
Studies in vivo and in vitro on the methylation of phosphatidyl-N,N-dimethylethanolamine to phosphatidylcholine in rat liver. Hoppe Seylers Z Physiol Chem (1973) 0.85
Metabolism of sphingosine bases. 8. Distribution, isolation and properties of D-3-oxosphinganine reductase. Stereospecificity of the NADPH-dependent reaction of 3-oxodihydrospingosine (2-amino-1-hydroxyoctadecane-3-one). Hoppe Seylers Z Physiol Chem (1968) 0.85
Primary structure of the C-terminal cyanogen bromide fragments II, III and IV from bovine brain proteolipid-apoprotein. Hoppe Seylers Z Physiol Chem (1982) 0.85
Distribution and properties of dihydrosphingosine-1-phosphate aldolase (sphinganine-1-phosphate alkanal-lyase). Hoppe Seylers Z Physiol Chem (1969) 0.85
Protein kinase C mediates transient spinule-type neurite outgrowth in the retina during light adaptation. Proc Natl Acad Sci U S A (1991) 0.85
Metabolism of sphingosine bases. 13. Enzymatic synthesis of 1-phosphate esters of 4t-sphingenine (sphingosine), sphinganine (dihydrosphingosine), 4-hydroxysphinganine (phytosphingosine) and 3-dehydrosphinganine by erythrocytes. Hoppe Seylers Z Physiol Chem (1970) 0.85
The organization of the human myelin basic protein gene. Comparison with the mouse gene. Biol Chem Hoppe Seyler (1989) 0.84
Molecular cloning and characterization of the mouse CGT gene encoding UDP-galactose ceramide-galactosyltransferase (cerebroside synthetase). Genomics (1996) 0.84
Functional analysis of the glycosylation of murine acid sphingomyelinase. J Biol Chem (1996) 0.84
Amino-acid sequence of human and bovine brain myelin proteolipid protein (lipophilin) is completely conserved. Biol Chem Hoppe Seyler (1985) 0.83
13 C-nuclear magnetic resonance spectroscopic studies on saturated, mono-, di- and polyunsaturated fatty acids, phospho- and sphingolipids. Hoppe Seylers Z Physiol Chem (1972) 0.83
Metabolism of sphingosine bases, 18. Degradation in vitro of phytosphingosine (4d-hydroxysphinganine). Hoppe Seylers Z Physiol Chem (1972) 0.83