Published in Korean J Intern Med on January 01, 1994
Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction. Am J Hum Genet (1989) 62.23
Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care (1991) 9.95
Informativeness of human (dC-dA)n.(dG-dT)n polymorphisms. Genomics (1990) 9.41
Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus. N Engl J Med (1993) 3.96
Mutation in mitochondrial tRNA(Leu)(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness. Nat Genet (1992) 3.76
Disease associations. Chance, artifact, or susceptibility genes? Diabetes (1989) 3.12
Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytes. Diabetes (1990) 2.97
Association of genetic variant of the glucose transporter with non-insulin-dependent diabetes mellitus. Lancet (1988) 2.92
Linkage of type 2 diabetes to the glucokinase gene. Lancet (1992) 2.64
Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus. Nature (1992) 2.59
Kelly West Lecture 1991. Challenges in diabetes epidemiology--from West to the rest. Diabetes Care (1992) 2.20
Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion. Nat Genet (1992) 2.15
Primary pancreatic beta-cell secretory defect caused by mutations in glucokinase gene in kindreds of maturity onset diabetes of the young. Lancet (1992) 1.95
Lilly Lecture: molecular mechanisms of insulin resistance. Lessons from patients with mutations in the insulin-receptor gene. Diabetes (1992) 1.55
Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q. Proc Natl Acad Sci U S A (1991) 1.54
Diabetes: the genetic connections. Diabetologia (1979) 1.21
Lessons learned from molecular biology of insulin-gene mutations. Diabetes Care (1990) 1.16
Glucokinase gene is genetic marker for NIDDM in American blacks. Diabetes (1992) 1.08
Human glucokinase gene: isolation, structural characterization, and identification of a microsatellite repeat polymorphism. Mol Endocrinol (1992) 1.04
Glucokinase and NIDDM. A candidate gene that paid off. Diabetes (1992) 1.04
Insulin-receptor and apolipoprotein genes contribute to development of NIDDM in Chinese Americans. Diabetes (1989) 1.00
A novel point mutation in the human insulin gene giving rise to hyperproinsulinemia (proinsulin Kyoto). J Clin Invest (1992) 0.92
A genetic marker at the glucokinase gene locus for type 2 (non-insulin-dependent) diabetes mellitus in Mauritian Creoles. Diabetologia (1992) 0.81
Polymorphic microsatellite repeat markers at the glucokinase gene locus are positively associated with NIDDM in Japanese. Diabetes (1993) 0.80
Possible correlation between non-insulin dependent diabetes mellitus (NIDDM) and restriction fragment length polymorphism (RFLP) of the 5'-flanking region of insulin gene in Korean diabetic population. Korean J Intern Med (1987) 0.78
Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science (1997) 7.95
Control of circadian rhythms and photoperiodic flowering by the Arabidopsis GIGANTEA gene. Science (1999) 4.42
Vitrectomy for the treatment of full-thickness stage 3 or 4 macular holes. Results of a multicentered randomized clinical trial. The Vitrectomy for Treatment of Macular Hole Study Group. Arch Ophthalmol (1997) 3.99
Diversity of mucin genes, structure, function, and expression. Gastroenterology (1995) 3.97
PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254. Cell (1991) 3.95
Regulation of phospholipase C-gamma 1 by profilin and tyrosine phosphorylation. Science (1991) 3.89
The autosomal dominant hypophosphatemic rickets (ADHR) gene is a secreted polypeptide overexpressed by tumors that cause phosphate wasting. J Clin Endocrinol Metab (2001) 3.55
Biodegradable block copolymers as injectable drug-delivery systems. Nature (1997) 3.48
Predictors of hemorrhage in patients with untreated brain arteriovenous malformation. Neurology (2006) 3.46
Positive serum antibody and negative tissue staining for Helicobacter pylori in subjects with atrophic body gastritis. Gastroenterology (1991) 3.38
Molecular cloning of human intestinal mucin (MUC2) cDNA. Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor. J Biol Chem (1994) 3.29
T-DNA insertional mutagenesis for functional genomics in rice. Plant J (2000) 3.25
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes. Nat Med (2001) 3.07
Emerging invasive liver abscess caused by K1 serotype Klebsiella pneumoniae in Korea. J Infect (2006) 3.04
Survey of extended-spectrum beta-lactamases in clinical isolates of Escherichia coli and Klebsiella pneumoniae: prevalence of TEM-52 in Korea. J Clin Microbiol (1999) 3.04
Heterogeneity of mucin gene expression in normal and neoplastic tissues. Cancer Res (1993) 3.02
Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation. J Allergy Clin Immunol (1995) 2.88
Tripartite regulation of Gln3p by TOR, Ure2p, and phosphatases. J Biol Chem (2000) 2.86
Urachal remnant diseases: spectrum of CT and US findings. Radiographics (2001) 2.82
T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity. Science (1994) 2.81
Envelope-binding domain in the cationic amino acid transporter determines the host range of ecotropic murine retroviruses. J Virol (1993) 2.77
The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue. J Clin Invest (2001) 2.77
Course of tic severity in Tourette syndrome: the first two decades. Pediatrics (1998) 2.75
Survey of Klebsiella pneumoniae strains producing extended-spectrum beta-lactamases: prevalence of SHV-12 and SHV-2a in Korea. J Clin Microbiol (1998) 2.66
Molecular cloning of human intestinal mucin cDNAs. Sequence analysis and evidence for genetic polymorphism. J Biol Chem (1989) 2.57
Autologous mesenchymal stem cell therapy delays the progression of neurological deficits in patients with multiple system atrophy. Clin Pharmacol Ther (2007) 2.55
Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression. Cancer Res (1999) 2.54
Vision-threatening complications of surgery for full-thickness macular holes. Vitrectomy for Macular Hole Study Group. Ophthalmology (1997) 2.49
Association of the metabolic syndrome with intracranial atherosclerotic stroke. Neurology (2005) 2.45
Cloning, sequencing, and chromosomal localization of human term placental alkaline phosphatase cDNA. Proc Natl Acad Sci U S A (1985) 2.44
Psychiatric epidemiology in Korea. Part I: Gender and age differences in Seoul. J Nerv Ment Dis (1990) 2.42
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. Oncogene (2012) 2.41
Xanthogranulomatous cholecystitis: CT features with emphasis on differentiation from gallbladder carcinoma. Radiology (1997) 2.34
Direct measurement of the electronic spin diffusion length in a fully functional organic spin valve by low-energy muon spin rotation. Nat Mater (2008) 2.33
Fetal exposure to an intra-amniotic inflammation and the development of cerebral palsy at the age of three years. Am J Obstet Gynecol (2000) 2.30
Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha), neonatal brain white matter lesions, and cerebral palsy. Am J Obstet Gynecol (1997) 2.30
Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease. Proc Natl Acad Sci U S A (1997) 2.24
Two-dimensional IR spectroscopy can be designed to eliminate the diagonal peaks and expose only the crosspeaks needed for structure determination. Proc Natl Acad Sci U S A (2001) 2.21
Alterations in human colonic mucin occurring with cellular differentiation and malignant transformation. Proc Natl Acad Sci U S A (1982) 2.17
Polyphosphoinositides produced by phosphatidylinositol 3-kinase are poor substrates for phospholipases C from rat liver and bovine brain. J Biol Chem (1989) 2.15
Exon trapping: a genetic screen to identify candidate transcribed sequences in cloned mammalian genomic DNA. Proc Natl Acad Sci U S A (1990) 2.15
Normal values for high-resolution anorectal manometry/topography in a healthy Korean population and the effects of gender and body mass index. Neurogastroenterol Motil (2014) 2.14
Endoscopic resection of submucosal tumor of the esophagus: results in 62 patients. Endoscopy (1997) 2.11
Abdominal amyloidosis: spectrum of radiological findings. Clin Radiol (2003) 2.10
Increased incidence of herpes zoster in the setting of cytomegalovirus preemptive therapy after kidney transplantation. Transpl Infect Dis (2013) 2.09
Remodelling of nasal mucosa in mild and severe persistent allergic rhinitis with special reference to the distribution of collagen, proteoglycans, and lymphatic vessels. Clin Exp Allergy (2010) 2.04
Regulation of postsynaptic structure and protein localization by the Rho-type guanine nucleotide exchange factor dPix. Neuron (2001) 2.01
Anchorage-independent cell growth signature identifies tumors with metastatic potential. Oncogene (2009) 1.99
The human MUC2 intestinal mucin has cysteine-rich subdomains located both upstream and downstream of its central repetitive region. J Biol Chem (1992) 1.98
A placebo-controlled study of guanfacine in the treatment of children with tic disorders and attention deficit hyperactivity disorder. Am J Psychiatry (2001) 1.95
Expression of Tn, sialosyl-Tn, and T antigens in human colon cancer. Cancer Res (1989) 1.93
Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: a possible signal for vessel development. Dev Dyn (2001) 1.93
Cross-modal plasticity and cochlear implants. Nature (2001) 1.92
Selenocysteine tRNA[Ser]Sec gene is ubiquitous within the animal kingdom. Mol Cell Biol (1990) 1.91
Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells. Biochem Biophys Res Commun (1999) 1.90
Somatic mutation of the MEN1 gene in parathyroid tumours. Nat Genet (1997) 1.90
Human gastric mucin. Identification of a unique species by expression cloning. J Biol Chem (1993) 1.90
Volumetric feedback ablation of uterine fibroids using magnetic resonance-guided high intensity focused ultrasound therapy. Eur Radiol (2011) 1.89
Molecular cloning of cDNAs derived from a novel human intestinal mucin gene. Biochem Biophys Res Commun (1990) 1.88
Management of foreign bodies in the gastrointestinal tract: an analysis of 104 cases in children. Endoscopy (1999) 1.87
Chemotherapeutic trial to control enterobiasis in schoolchildren. Korean J Parasitol (1997) 1.86
Insulin secretory dysfunction and insulin resistance in the pathogenesis of korean type 2 diabetes mellitus. Metabolism (2001) 1.83
Molecular epidemiological analysis of quinolone-resistant Escherichia coli causing bacteremia in neutropenic patients with leukemia in Korea. Clin Infect Dis (1997) 1.83
A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus. Genome Res (1997) 1.82
Investigation of human brain hemodynamics by simultaneous near-infrared spectroscopy and functional magnetic resonance imaging. Med Phys (2001) 1.81
Coexistence of static magnetism and superconductivity in SmFeAsO(1-x)F(x) as revealed by muon spin rotation. Nat Mater (2009) 1.79
Interleukin-6 concentrations in umbilical cord plasma are elevated in neonates with white matter lesions associated with periventricular leukomalacia. Am J Obstet Gynecol (1996) 1.79
Randomized phase 2b trial of tofacitinib (CP-690,550) in de novo kidney transplant patients: efficacy, renal function and safety at 1 year. Am J Transplant (2012) 1.79
Symptomatic duodenal diverticulum. World J Surg (1995) 1.78
Efficient detection of hereditary nonpolyposis colorectal cancer gene carriers by screening for tumor microsatellite instability before germline genetic testing. Gastroenterology (2001) 1.78
Relationship between sonographic and pathologic findings in epidermal inclusion cysts. J Clin Ultrasound (2001) 1.77
Biosynthesis of human colonic mucin: Muc2 is the prominent secretory mucin. Gastroenterology (1994) 1.77
Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states. Hum Mol Genet (1997) 1.77
Analysis of errors in medical rapid prototyping models. Int J Oral Maxillofac Surg (2002) 1.76
Amniotic fluid interleukin-6: a sensitive test for antenatal diagnosis of acute inflammatory lesions of preterm placenta and prediction of perinatal morbidity. Am J Obstet Gynecol (1995) 1.76
The fallacy of the levator expansion theory. Plast Reconstr Surg (1999) 1.75
Low-copy plasmids can perform as well as or better than high-copy plasmids for metabolic engineering of bacteria. Metab Eng (2000) 1.75
Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor. Cancer Res (2001) 1.73
Serotonin transporter gene polymorphism and irritable bowel syndrome. Neurogastroenterol Motil (2006) 1.72
Sialosyl-Tn. A novel mucin antigen associated with prognosis in colorectal cancer patients. Cancer (1990) 1.70
Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung. Hum Mol Genet (1997) 1.70
Molecular cloning and expression of a complementary DNA for inositol 1,4,5-trisphosphate 3-kinase. Science (1990) 1.70
Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase. Cancer Res (2000) 1.70
The inflammation hypothesis of aging: molecular modulation by calorie restriction. Ann N Y Acad Sci (2001) 1.70
Inhibition of mucin glycosylation by aryl-N-acetyl-alpha-galactosaminides in human colon cancer cells. J Biol Chem (1989) 1.68
Increased expression of cyclooxygenase-2 protein in human gastric carcinoma. Clin Cancer Res (2000) 1.67
Cutaneous adverse effects in patients treated with the multitargeted kinase inhibitors sorafenib and sunitinib. Br J Dermatol (2009) 1.67
A comparison of three immunoperoxidase techniques for antigen detection in colorectal carcinoma tissues. J Histochem Cytochem (1988) 1.67
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Pharmacological preconditioning with low-dose cyclosporine or FK506 reduces subsequent ischemia/reperfusion injury in rat kidney. Transplantation (2001) 1.67
Mucin gene expression in normal, preneoplastic, and neoplastic human gastric epithelium. Cancer Res (1995) 1.66
Expression of MUC1 and MUC2 mucins in gastric carcinomas: its relationship with the prognosis of the patients. Clin Cancer Res (1998) 1.66
A gene cluster encoding malonyl-CoA decarboxylase (MatA), malonyl-CoA synthetase (MatB) and a putative dicarboxylate carrier protein (MatC) in Rhizobium trifolii--cloning, sequencing, and expression of the enzymes in Escherichia coli. Eur J Biochem (1998) 1.66
Association between hepatitis B virus infection and HLA-DR type in Korea. Hepatology (2000) 1.65
Glycoprortein biosynthesis in small intestinal mucosa. I. A study of glycosyltransferases in microsomal subfractions. J Biol Chem (1971) 1.65
Intravenous calcitriol regresses myocardial hypertrophy in hemodialysis patients with secondary hyperparathyroidism. Am J Kidney Dis (1999) 1.63
Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription. J Clin Invest (1997) 1.63
Mortality among workers at a butadiene facility. Am J Ind Med (1987) 1.62