Spontaneous, heritable colitis in a new substrain of C3H/HeJ mice.

PubWeight™: 1.56‹?› | Rank: Top 4%

🔗 View Article (PMID 7958684)

Published in Gastroenterology on December 01, 1994

Authors

J P Sundberg1, C O Elson, H Bedigian, E H Birkenmeier

Author Affiliations

1: Jackson Laboratory, Bar Harbor, Maine.

Articles citing this

Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses. J Clin Invest (1996) 7.97

Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis. Gut (2004) 3.17

Differential roles of segmented filamentous bacteria and clostridia in development of the intestinal immune system. Infect Immun (1999) 3.03

CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: increased T helper cell type 1 response and ability to transfer disease. J Exp Med (1998) 3.01

Clinical aspects and pathophysiology of inflammatory bowel disease. Clin Microbiol Rev (2002) 2.29

Inflammatory bowel disease-like enteritis and caecitis in a senescence accelerated mouse P1/Yit strain. Gut (1998) 2.20

Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn's disease. J Clin Invest (2001) 1.96

T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis. J Exp Med (2002) 1.69

Quantitative assessment of the human gut microbiome using multitag pyrosequencing. Chem Biodivers (2010) 1.68

Nitric oxide in inflammatory bowel disease: a universal messenger in an unsolved puzzle. Immunology (2004) 1.54

Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease. J Clin Invest (2004) 1.50

Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human genetics. Front Immunol (2013) 1.41

Layers of mutualism with commensal bacteria protect us from intestinal inflammation. Gut (2006) 1.36

Intestinal effector T cells in health and disease. Immunity (2009) 1.24

Refined histopathologic scoring system improves power to detect colitis QTL in mice. Mamm Genome (2004) 1.20

Modulating the intestinal immune system: the role of lymphotoxin and GALT organs. Gut (2004) 1.17

pANCA represents a cross-reactivity to enteric bacterial antigens. J Clin Immunol (1998) 1.13

Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models. Mutat Res (2010) 1.06

TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions. PLoS One (2011) 0.98

Tumour necrosis factor in mouse models of chronic intestinal inflammation. Immunology (2002) 0.96

Animal models of intestinal inflammation: ineffective communication between coalition members. Springer Semin Immunopathol (2005) 0.91

Quantitative lymphatic vessel trait analysis suggests Vcam1 as candidate modifier gene of inflammatory bowel disease. Genes Immun (2010) 0.89

Intestinal epithelium in inflammatory bowel disease. Front Med (Lausanne) (2014) 0.84

Alterations of colonic contractility in an interleukin-10 knockout mouse model of inflammatory bowel disease. J Neurogastroenterol Motil (2015) 0.79

Enterorhabdus caecimuris sp. nov., a member of the family Coriobacteriaceae isolated from a mouse model of spontaneous colitis, and emended description of the genus Enterorhabdus Clavel et al. 2009. Int J Syst Evol Microbiol (2009) 0.78

Ion transport across the cecum in normal and colitic mice. Dig Dis Sci (1999) 0.77

Microbiota-specific Th17 Cells: Yin and Yang in Regulation of Inflammatory Bowel Disease. Inflamm Bowel Dis (2016) 0.75

Application of Zebrafish Models in Inflammatory Bowel Disease. Front Immunol (2017) 0.75

Uncovering Pathogenic Mechanisms of Inflammatory Bowel Disease Using Mouse Models of Crohn's Disease-Like Ileitis: What is the Right Model? Cell Mol Gastroenterol Hepatol (2017) 0.75

Alopecia areata. Nat Rev Dis Prim (2017) 0.75

Articles by these authors

Maps from two interspecific backcross DNA panels available as a community genetic mapping resource. Mamm Genome (1994) 5.38

A nuclear extract of Xenopus laevis oocytes that accurately transcribes 5S RNA genes. Cell (1978) 5.29

Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice. Gastroenterology (1994) 4.57

Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin. J Immunol (1984) 3.89

T-cell regulation of murine IgA synthesis. J Exp Med (1979) 3.11

CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: increased T helper cell type 1 response and ability to transfer disease. J Exp Med (1998) 3.01

Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis. Am J Physiol (1998) 2.76

Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues. J Exp Med (1993) 2.62

Cholera toxin feeding did not induce oral tolerance in mice and abrogated oral tolerance to an unrelated protein antigen. J Immunol (1984) 2.51

A lavage technique allowing repeated measurement of IgA antibody in mouse intestinal secretions. J Immunol Methods (1984) 2.41

Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group. Gastroenterology (2000) 2.23

The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships. J Biol Chem (1987) 2.13

Transgenic mice containing intestinal fatty acid-binding protein-human growth hormone fusion genes exhibit correct regional and cell-specific expression of the reporter gene in their small intestine. Proc Natl Acad Sci U S A (1988) 2.12

Mechanisms underlying generation of gradients in gene expression within the intestine: an analysis using transgenic mice containing fatty acid binding protein-human growth hormone fusion genes. Genes Dev (1988) 2.01

Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn's disease. Crohn's Disease Study Group. Gastroenterology (1997) 2.00

The fatty liver dystrophy (fld) mutation. A new mutant mouse with a developmental abnormality in triglyceride metabolism and associated tissue-specific defects in lipoprotein lipase and hepatic lipase activities. J Biol Chem (1989) 1.91

Use of transgenic mice to map cis-acting elements in the intestinal fatty acid binding protein gene (Fabpi) that control its cell lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axes of the gut epithelium. J Cell Biol (1992) 1.87

Optimizing oral vaccines: induction of systemic and mucosal B-cell and antibody responses to tetanus toxoid by use of cholera toxin as an adjuvant. Infect Immun (1993) 1.78

Collagen content and types in the intestinal strictures of Crohn's disease. Gastroenterology (1988) 1.77

Regulation of IgA synthesis and immune response by T cells and interleukins. J Clin Immunol (1989) 1.76

Enzyme replacement therapy for murine mucopolysaccharidosis type VII. J Clin Invest (1994) 1.73

Oral tolerance in humans. T cell but not B cell tolerance after antigen feeding. J Immunol (1994) 1.72

Spontaneously colitic C3H/HeJBir mice demonstrate selective antibody reactivity to antigens of the enteric bacterial flora. J Immunol (1997) 1.69

Differential homing commitments of antigen-specific T cells after oral or parenteral immunization in humans. J Immunol (1999) 1.60

Mutations in a NIMA-related kinase gene, Nek1, cause pleiotropic effects including a progressive polycystic kidney disease in mice. Proc Natl Acad Sci U S A (2000) 1.57

Reversal of pathology in murine mucopolysaccharidosis type VII by somatic cell gene transfer. Nature (1993) 1.55

A murine model of mucopolysaccharidosis VII. Gross and microscopic findings in beta-glucuronidase-deficient mice. Am J Pathol (1990) 1.53

Cholera toxin and its subunits as potential oral adjuvants. Curr Top Microbiol Immunol (1989) 1.43

The SV40 DNA template for transcription of late mRNA in viral nucleoprotein complexes. Cell (1977) 1.42

A single-base-pair deletion in the beta-glucuronidase gene accounts for the phenotype of murine mucopolysaccharidosis type VII. Proc Natl Acad Sci U S A (1993) 1.40

Analysis of the tissue-specific expression, developmental regulation, and linkage relationships of a rodent gene encoding heart fatty acid binding protein. J Biol Chem (1987) 1.40

Characterization of the peripheral neuropathy in neonatal and adult mice that are homozygous for the fatty liver dystrophy (fld) mutation. J Biol Chem (1991) 1.39

Inhibition of murine lymphocyte proliferation by the B subunit of cholera toxin. J Immunol (1987) 1.39

Developmental regulation of a gene that encodes a cysteine-rich intestinal protein and maps near the murine immunoglobulin heavy chain locus. Proc Natl Acad Sci U S A (1986) 1.38

Abnormal regulation of immunoglobulin synthesis in vitro in primary biliary cirrhosis. Gastroenterology (1980) 1.36

Deficiency of the tryptase-positive, chymase-negative mast cell type in gastrointestinal mucosa of patients with defective T lymphocyte function. J Immunol (1987) 1.34

Murine mucopolysaccharidosis type VII: long term therapeutic effects of enzyme replacement and enzyme replacement followed by bone marrow transplantation. J Clin Invest (1997) 1.33

Enzyme replacement with recombinant beta-glucuronidase in murine mucopolysaccharidosis type VII: impact of therapy during the first six weeks of life on subsequent lysosomal storage, growth, and survival. Pediatr Res (1996) 1.33

Intestinal IgA: novel views on its function in the defence of the largest mucosal surface. Gut (1999) 1.32

Intestinal immunity and inflammation: recent progress. Gastroenterology (1986) 1.32

Adaptive immunity in the host-microbiota dialog. Mucosal Immunol (2010) 1.31

Enzyme replacement in murine mucopolysaccharidosis type VII: neuronal and glial response to beta-glucuronidase requires early initiation of enzyme replacement therapy. Pediatr Res (1999) 1.31

Enhancing effect of cholera toxin on interleukin-6 secretion by IEC-6 intestinal epithelial cells: mode of action and augmenting effect of inflammatory cytokines. Infect Immun (1993) 1.31

A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice. Proc Natl Acad Sci U S A (2001) 1.30

Cells and cytokines in mucosal immunity and inflammation. Gastroenterol Clin North Am (1992) 1.30

Genetic analysis of susceptibility to dextran sulfate sodium-induced colitis in mice. Genomics (1999) 1.29

Human host response to Giardia lamblia. I. Spontaneous killing by mononuclear leukocytes in vitro. J Immunol (1982) 1.26

An evaluation of total parenteral nutrition in the management of inflammatory bowel disease. Dig Dis Sci (1980) 1.26

Small intestinal injury in the graft versus host reaction: an innocent bystander phenomenon. Gastroenterology (1977) 1.25

Collagen synthesis by human intestinal smooth muscle cells in culture. Gastroenterology (1987) 1.24

A method of obtaining, processing, and analyzing human intestinal secretions for antibody content. J Immunol Methods (1988) 1.24

Male and female mouse DNAs can be discriminated using retroviral probes. Nature (1982) 1.24

Molecular and genetic characterization of GABP beta. Genes Dev (1994) 1.23

Enzyme replacement with recombinant beta-glucuronidase in the newborn mucopolysaccharidosis type VII mouse. Pediatr Res (1993) 1.23

The human sucrase-isomaltase gene directs complex patterns of gene expression in transgenic mice. Am J Physiol (1993) 1.23

Covert suppressor T cells in Crohn's disease. Gastroenterology (1981) 1.22

T cell-B cell regulation in the intestinal lamina propria in Crohn's disease. Gastroenterology (1985) 1.21

The mucosal adjuvanticity of cholera toxin involves enhancement of costimulatory activity by selective up-regulation of B7.2 expression. J Immunol (1997) 1.21

Mice deficient in Th1- and Th2-type cytokines develop distinct forms of hapten-induced colitis. Gastroenterology (2000) 1.20

Characterization of simian virus 40 tsA58 transcriptional intermediates at restrictive temperatures: relationship between DNA replication and transcription. J Virol (1977) 1.20

Polymicrobial sepsis following endoscopic retrograde cholangiopancreatography. Gastroenterology (1975) 1.19

Differences in intraepithelial lymphocyte T cell subsets isolated from murine small versus large intestine. J Immunol (1995) 1.18

Heritable susceptibility for colitis in mice induced by IL-10 deficiency. Inflamm Bowel Dis (2000) 1.17

Regulation of simian virus 40 early and late gene transcription without viral DNA replication. J Virol (1979) 1.14

pANCA represents a cross-reactivity to enteric bacterial antigens. J Clin Immunol (1998) 1.13

Clinical and pathologic findings in two new allelic murine models of polycystic kidney disease. J Am Soc Nephrol (1999) 1.12

Temporal and spatial patterns of transgene expression in aging adult mice provide insights about the origins, organization, and differentiation of the intestinal epithelium. Proc Natl Acad Sci U S A (1991) 1.10

Induction and control of the gastrointestinal immune system. Scand J Gastroenterol Suppl (1985) 1.10

Mouse sn-glycerol-3-phosphate dehydrogenase: molecular cloning and genetic mapping of a cDNA sequence. Proc Natl Acad Sci U S A (1983) 1.09

Genetic control of the murine immune response to cholera toxin. J Immunol (1985) 1.08

Deficiency of the autologous mixed lymphocyte reaction in patients with primary biliary cirrhosis. J Clin Invest (1980) 1.07

Commensal bacteria as targets in Crohn's disease. Gastroenterology (2000) 1.07

Colitis induced by enteric bacterial antigen-specific CD4+ T cells requires CD40-CD40 ligand interactions for a sustained increase in mucosal IL-12. J Immunol (2000) 1.07

The cellular retinol binding protein II gene. Sequence analysis of the rat gene, chromosomal localization in mice and humans, and documentation of its close linkage to the cellular retinol binding protein gene. J Biol Chem (1987) 1.06

Ir gene control of the murine secretory IgA response to cholera toxin. Eur J Immunol (1987) 1.06

Correction of murine mucopolysaccharidosis VII by a human beta-glucuronidase transgene. Proc Natl Acad Sci U S A (1990) 1.06

Persistent clonal expansions of peripheral blood CD4+ lymphocytes in chronic inflammatory bowel disease. J Immunol (1996) 1.06

A novel model of murine mucopolysaccharidosis type VII due to an intracisternal a particle element transposition into the beta-glucuronidase gene: clinical and pathologic findings. Pediatr Res (2001) 1.04

Kinetics of cytokine expression during healing of acute colitis in mice. Am J Physiol (1996) 1.01

Reduction in oral immunogenicity of cholera toxin B subunit by N-terminal peptide addition. Infect Immun (1993) 1.01

Transcription initiation of Xenopus 5S ribosomal RNA genes in vitro. Nucleic Acids Res (1979) 1.00

Syngeneic bone marrow transplantation reduces the hearing loss associated with murine mucopolysaccharidosis type VII. Blood (1995) 1.00

Identification of Pneumocystis carinii in immunodeficient mice. Lab Anim Sci (1989) 0.99

Neuropathology of murine mucopolysaccharidosis type VII. Acta Neuropathol (1996) 0.99

Epithelial cell differentiation in normal and transgenic mouse intestinal isografts. J Cell Biol (1991) 0.99

Identification and genetic mapping of a new polycystic kidney disease on mouse chromosome 8. Genomics (1997) 0.98

Effects of cholera toxin on macrophage production of co-stimulatory cytokines. Eur J Immunol (2001) 0.98

Comparative effectiveness of the cholera toxin B subunit and alkaline phosphatase as carriers for oral vaccines. Infect Immun (1993) 0.98

Expression of liver fatty acid-binding protein/human growth hormone fusion genes within the enterocyte and enteroendocrine cell populations of fetal transgenic mice. J Biol Chem (1991) 0.97

Human host response to Giardia lamblia. II. Antibody-dependent killing in vitro. Cell Immunol (1983) 0.96

Evolution of the apolipoproteins. Structure of the rat apo-A-IV gene and its relationship to the human genes for apo-A-I, C-III, and E. J Biol Chem (1986) 0.96

Linkage of Crohn's disease-related serological phenotypes: NFKB1 haplotypes are associated with anti-CBir1 and ASCA, and show reduced NF-kappaB activation. Gut (2008) 0.93

Pathology of the ear in murine mucopolysaccharidosis type VII. Morphologic correlates of hearing loss. Lab Invest (1994) 0.93

Intracisternal A-particle element transposition into the murine beta-glucuronidase gene correlates with loss of enzyme activity: a new model for beta-glucuronidase deficiency in the C3H mouse. Mol Cell Biol (1998) 0.92

Leukocytic endogenous mediator in Crohn's disease. Infect Immun (1978) 0.92

Intraperitoneal immunization of human subjects with tetanus toxoid induces specific antibody-secreting cells in the peritoneal cavity and in the circulation, but fails to elicit a secretory IgA response. Clin Exp Immunol (1994) 0.91