Published in J Biol Chem on November 11, 1994
The biology of the Ets1 proto-oncogene. Mol Cancer (2003) 2.88
Ets-1 is a negative regulator of Th17 differentiation. J Exp Med (2007) 1.97
Characterization of the cooperative function of inhibitory sequences in Ets-1. Mol Cell Biol (1996) 1.85
A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein. EMBO J (1997) 1.60
The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability. Mol Cell Biol (1996) 1.51
Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition. Genes Dev (2000) 1.48
Net (ERP/SAP2) one of the Ras-inducible TCFs, has a novel inhibitory domain with resemblance to the helix-loop-helix motif. EMBO J (1996) 1.22
Transcription factor ERG variants and functional diversification of chondrocytes during limb long bone development. J Cell Biol (2000) 1.20
Regulation of cell cycle transcription factor Swi4 through auto-inhibition of DNA binding. Mol Cell Biol (1999) 1.10
The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor beta locus. Proc Natl Acad Sci U S A (2004) 1.08
Review of Ets1 structure, function, and roles in immunity. Cell Mol Life Sci (2013) 1.03
Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell (2014) 0.99
Transcriptional regulation of mouse L-selectin. Biochim Biophys Acta (2008) 0.98
Calcium regulation of GM-CSF by calmodulin-dependent kinase II phosphorylation of Ets1. Mol Biol Cell (2002) 0.92
The p42 variant of ETS1 protein rescues defective Fas-induced apoptosis in colon carcinoma cells. Proc Natl Acad Sci U S A (1999) 0.90
Correlated motions and interactions at the onset of the DNA-induced partial unfolding of Ets-1. Biophys J (2009) 0.89
Thymomegaly, microsplenia, and defective homeostatic proliferation of peripheral lymphocytes in p51-Ets1 isoform-specific null mice. Mol Cell Biol (2007) 0.85
Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter. Proc Natl Acad Sci U S A (2013) 0.85
Crystallization of the Ets1-Runx1-CBFβ-DNA complex formed on the TCRα gene enhancer. Acta Crystallogr F Struct Biol Commun (2014) 0.77
The c-erb-A protein is a high-affinity receptor for thyroid hormone. Nature (1987) 7.06
A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia. Science (1997) 4.29
Combinatorial generation of variable fusion proteins in the Ewing family of tumours. EMBO J (1993) 2.91
Cooperative binding of Ets-1 and core binding factor to DNA. Mol Cell Biol (1994) 2.27
DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma. Mol Cell Biol (1994) 2.18
A domain containing leucine-zipper-like motifs mediate novel in vivo interactions between the thyroid hormone and retinoic acid receptors. Mol Endocrinol (1989) 2.16
Homologous tyrosine phosphorylation sites in transformation-specific gene products of distinct avian sarcoma viruses. Nature (1981) 2.11
Tyrosine-specific protein kinase activity associated with p105 of avian sarcoma virus PRCII. Virology (1981) 2.03
The product of the c-ets-1 proto-oncogene and the related Ets2 protein act as transcriptional activators of the long terminal repeat of human T cell leukemia virus HTLV-1. EMBO J (1990) 2.03
Bovine leukemia virus: an exogenous RNA oncogenic virus. Proc Natl Acad Sci U S A (1976) 2.01
Identification in chickens of an evolutionarily conserved cellular ets-2 gene (c-ets-2) encoding nuclear proteins related to the products of the c-ets proto-oncogene. EMBO J (1988) 1.99
Identification and preferential expression in thymic and bursal lymphocytes of a c-ets oncogene-encoded Mr 54,000 cytoplasmic protein. Proc Natl Acad Sci U S A (1986) 1.89
Identification of nucleotide preferences in DNA sequences recognised specifically by c-Ets-1 protein. Nucleic Acids Res (1992) 1.82
Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1. Mol Cell Biol (1992) 1.81
Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimers. Mol Endocrinol (1992) 1.71
Definition of an Ets1 protein domain required for nuclear localization in cells and DNA-binding activity in vitro. Mol Cell Biol (1989) 1.67
A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein. EMBO J (1997) 1.60
Translation of bovine leukemia virus virion RNAs in heterologous protein-synthesizing systems. J Virol (1979) 1.60
Mitogenic stimulation of thymocytes results in the calcium-dependent phosphorylation of c-ets-1 proteins. EMBO J (1988) 1.58
Synergistic activation of the HTLV1 LTR Ets-responsive region by transcription factors Ets1 and Sp1. EMBO J (1993) 1.57
GATA and Ets cis-acting sequences mediate megakaryocyte-specific expression. Mol Cell Biol (1993) 1.57
Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells. Blood (2000) 1.52
The bovine leukemia virus p34 is a transactivator protein. EMBO J (1987) 1.48
Expression of the v-erbA oncogene in chicken embryo fibroblasts stimulates their proliferation in vitro and enhances tumor growth in vivo. Cell (1987) 1.46
A phorbol ester response element within the human T-cell receptor beta-chain enhancer. Proc Natl Acad Sci U S A (1992) 1.44
Dual control of myc expression through a single DNA binding site targeted by ets family proteins and E2F-1. Oncogene (1994) 1.40
TEL is a sequence-specific transcriptional repressor. J Biol Chem (1999) 1.39
Activation of protein kinase C or cAMP-dependent protein kinase increases phosphorylation of the c-erbA-encoded thyroid hormone receptor and of the v-erbA-encoded protein. EMBO J (1988) 1.37
The c-ets-1 protein is chromatin associated and binds to DNA in vitro. Oncogene (1989) 1.36
Induction of proliferation or transformation of neuroretina cells by the mil and myc viral oncogenes. Nature (1985) 1.32
Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia-associated TEL-AML1 oncoprotein. Blood (2000) 1.29
TEL-JAK2 transgenic mice develop T-cell leukemia. Blood (2000) 1.26
A transcriptional regulatory element is associated with a nuclease-hypersensitive site in the pol gene of human immunodeficiency virus type 1. J Virol (1994) 1.26
Humoral antibody response to bovine leukemia virus infection in cattle and sheep. Cancer Res (1979) 1.24
Sequence-specific interaction of the Ets1 protein with the long terminal repeat of the human T-lymphotropic virus type I. J Virol (1991) 1.23
Proteins of the ETS family with transcriptional repressor activity. Oncogene (2000) 1.23
Integration of bovine leukemia virus DNA in the bovine genome. Proc Natl Acad Sci U S A (1979) 1.23
Esh avian sarcoma virus codes for a gag-linked transformation-specific protein with an associated protein kinase activity. Virology (1981) 1.23
Identification in chicken macrophages of a set of proteins related to, but distinct from, the chicken cellular c-ets-encoded protein p54c-ets. EMBO J (1986) 1.22
junB promoter regulation: Ras mediated transactivation by c-Ets-1 and c-Ets-2. Oncogene (1994) 1.22
A third class of avian sarcoma viruses, defined by related transformation-specific proteins of Yamaguchi 73 and Esh sarcoma viruses. Proc Natl Acad Sci U S A (1981) 1.22
Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemia. Leukemia (2010) 1.22
Multiple domains for the chicken cellular sequences homologous to the v-ets oncogene of the E26 retrovirus. Mol Cell Biol (1987) 1.20
Rapid and transient expression of Ets2 in mature macrophages following stimulation with cMGF, LPS, and PKC activators. Genes Dev (1990) 1.19
The t(1;12)(q21;p13) translocation of human acute myeloblastic leukemia results in a TEL-ARNT fusion. Proc Natl Acad Sci U S A (2000) 1.19
The TEL gene products: nuclear phosphoproteins with DNA binding properties. Oncogene (1997) 1.17
Comparison of constitutional and tumor-associated 11;22 translocations: nonidentical breakpoints on chromosomes 11 and 22. Proc Natl Acad Sci U S A (1986) 1.16
Analysis of the thrombopoietin receptor (MPL) promoter implicates GATA and Ets proteins in the coregulation of megakaryocyte-specific genes. Blood (1996) 1.16
Cloning and expression of chicken p54c-ets cDNAs: the first p54c-ets coding exon is located into the 40.0 kbp genomic domain unrelated to v-ets. Oncogene Res (1988) 1.15
Bovine leukemia virus. Curr Top Microbiol Immunol (1984) 1.15
FLI-1 inhibits differentiation and induces proliferation of primary erythroblasts. Oncogene (1999) 1.15
Bovine leukemia virus involvement in enzootic bovine leukosis. Adv Cancer Res (1978) 1.12
Participation of Ets transcription factors in the glucocorticoid response of the rat tyrosine aminotransferase gene. Mol Cell Biol (1994) 1.11
Phosphorylation of the v-erbA protein is required for its function as an oncogene. Genes Dev (1990) 1.11
Translocation of a store of maternal cytoplasmic c-myc protein into nuclei during early development. Mol Cell Biol (1989) 1.10
A 43-kDa protein related to c-Erb A alpha 1 is located in the mitochondrial matrix of rat liver. J Biol Chem (1995) 1.10
The c-erbA alpha-encoded thyroid hormone receptor is phosphorylated in its amino terminal domain by casein kinase II. Oncogene (1989) 1.10
Frog oocytes synthesize and completely process the precursor polypeptide to virion structural proteins after microinjection of avian myeloblastosis virus RNA. Proc Natl Acad Sci U S A (1977) 1.08
A single amino-acid substitution in the Ets domain alters core DNA binding specificity of Ets1 to that of the related transcription factors Elf1 and E74. Nucleic Acids Res (1993) 1.07
Ets transcription factors bind and transactivate the core promoter of the von Willebrand factor gene. Oncogene (1997) 1.07
Transformation of quail embryo fibroblasts by a retrovirus carrying a normal human c-myc gene. EMBO J (1986) 1.06
Monoclonal antibodies to hemagglutinin-neuraminidase and fusion glycoproteins of Newcastle disease virus: relationship between glycosylation and reactivity. J Virol (1986) 1.06
Characterization of a hepatoma mRNA transcribed from a third promoter of a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-encoding gene and controlled by ets oncogene-related products. Proc Natl Acad Sci U S A (1993) 1.05
Biologically active epitopes of bovine leukemia virus glycoprotein gp51: their dependence on protein glycosylation and genetic variability. Virology (1984) 1.03
Constitutive STAT5 activation specifically cooperates with the loss of p53 function in B-cell lymphomagenesis. Oncogene (2006) 1.02
Myb protein binds to multiple sites in the human T cell lymphotropic virus type 1 long terminal repeat and transactivates LTR-mediated expression. Virology (1992) 1.02
Analysis of the DNA binding and transcriptional activation properties of the Ets1 oncoprotein. New Biol (1992) 1.00
Identification of a Ets1 variant protein unaffected in its chromatin and in vitro DNA binding capacities by T cell antigen receptor triggering and intracellular calcium rises. Oncogene (1990) 1.00
Expression of the v-src or v-fps oncogene increases fructose 2,6-bisphosphate in chick-embryo fibroblasts. Novel mechanism for the stimulation of glycolysis by retroviruses. Biochem J (1986) 0.99
Leukemia-initiating cell activity requires calcineurin in T-cell acute lymphoblastic leukemia. Leukemia (2013) 0.98
Myb and Ets related transcription factors are required for activity of the human lck type I promoter. Oncogene (1994) 0.97
Characterization of a novel ETS gene, TELB, encoding a protein structurally and functionally related to TEL. Oncogene (2000) 0.96
Requirement of an ETS-binding element for transcription of the human lck type I promoter. Oncogene (1993) 0.96
Ligation of membrane Ig leads to calcium-mediated phosphorylation of the proto-oncogene product, Ets-1. J Immunol (1991) 0.96
Phosphorylation of Ets1 regulates the complementation of a CSF-1 receptor impaired in mitogenesis. Oncogene (1996) 0.96
Isolation of two different c-ets-2 proto-oncogenes in Xenopus laevis. Nucleic Acids Res (1990) 0.94
Cleavage of four avian sarcoma virus polyproteins with virion protease p15 removes gag sequences and yields large fragments that function as tyrosine phosphoacceptors in vitro. Proc Natl Acad Sci U S A (1981) 0.94
IL-2 and long-term T cell activation induce physical and functional interaction between STAT5 and ETS transcription factors in human T cells. Oncogene (2000) 0.93
A novel way to induce erythroid progenitor self renewal: cooperation of c-Kit with the erythropoietin receptor. Biol Chem (1999) 0.92
Regulation of parathyroid hormone-related protein (PTHrP) gene expression. Sp1 binds through an inverted CACCC motif and regulates promoter activity in cooperation with Ets1. J Biol Chem (1994) 0.92
Ets1, when fused to the GAL4 DNA binding domain, efficiently enhances galactose promotor dependent gene expression in yeast. Oncogene (1991) 0.91
Diagnostic tests of bovine leukemia: comparison between an hematological test and the serological diagnosis. Eur J Cancer (1976) 0.91
Elf-1 contributes to the function of the complex interleukin (IL)-2-responsive enhancer in the mouse IL-2 receptor alpha gene. J Exp Med (1997) 0.90
Cloning, sequencing, and expression of two Xenopus laevis c-ets-2 protooncogenes. Cell Growth Differ (1991) 0.88
Analysis of TEL proteins in human leukemias. Oncogene (1998) 0.88
The 5' extremity of the v-ets oncogene of avian leukemia virus E26 encodes amino acid sequences not derived from the major c-ets-encoded cellular proteins. Virology (1987) 0.87
Characterization of the chronic myelomonocytic leukemia associated TEL-PDGF beta R fusion protein. Oncogene (1999) 0.87
Spi-1 and mutant p53 regulate different aspects of the proliferation and differentiation control of primary erythroid progenitors. Oncogene (1995) 0.87
[Preparation and characterization of specific antisera directed against different polypeptide domains encoded by the c-myc oncogene for studying the expression of this gene introduced into quail or rat cells]. C R Acad Sci III (1986) 0.86
Tissue-specific activity of the gammac chain gene promoter depends upon an Ets binding site and is regulated by GA-binding protein. J Biol Chem (1996) 0.85
Characterization of Xenopus laevis cDNA clones of the c-ets-1 proto-oncogene. Nucleic Acids Res (1990) 0.85
A transgenic mouse model for TEL-JAK2-induced B-cell lymphoma/leukemia. Leukemia (2006) 0.84
Biochemical approach to bovine leukemia. Acta Haematol (1975) 0.84
Repression of AP-1-stimulated transcription by c-Ets-1. J Biol Chem (1994) 0.84
Bovine leukaemia virus and enzootic bovine leukosis. Onderstepoort J Vet Res (1985) 0.84
Thyroid hormone action and the erbA oncogene family. Biochimie (1989) 0.83
The TEL-Jak2 oncoprotein induces Socs1 expression and altered cytokine response in Ba/F3 cells. Oncogene (2001) 0.83
Functional analyses of the TEL-ARNT fusion protein underscores a role for oxygen tension in hematopoietic cellular differentiation. Oncogene (2006) 0.83