Published in Mol Pharmacol on November 01, 1994
Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins. Mol Cell Biol (1999) 2.22
Linkage between reovirus-induced apoptosis and inhibition of cellular DNA synthesis: role of the S1 and M2 genes. J Virol (1996) 1.46
Sequestration of mammalian Rad51-recombination protein into micronuclei. J Cell Biol (1999) 1.33
Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity. Mol Cancer (2008) 1.01
Up-regulation of telomerase activity in human pancreatic cancer cells after exposure to etoposide. Br J Cancer (2000) 0.81
Mouse embryonic stem cells undergo charontosis, a novel programmed cell death pathway dependent upon cathepsins, p53, and EndoG, in response to etoposide treatment. Stem Cell Res (2013) 0.81
Effect of heat shock protein 72 expression on etoposide-induced cell death of rat retinal ganglion cells. Korean J Ophthalmol (2013) 0.80
Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response. J Biol Chem (2015) 0.77
Nuclear Compartmentalization of Serine Racemase Regulates d-Serine Production: IMPLICATIONS FOR N-METHYL-d-ASPARTATE (NMDA) RECEPTOR ACTIVATION. J Biol Chem (2015) 0.76
Caspase-dependent drug-induced apoptosis is regulated by cell surface sialylation in human B-cell lymphoma. Oncol Lett (2015) 0.75
Enterovirus 71 3C promotes apoptosis through cleavage of PinX1, a telomere binding protein. J Virol (2016) 0.75
Calcium dependence of toxic cell death: a final common pathway. Science (1979) 3.35
The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition. J Biol Chem (1998) 2.35
Myocardial ischemia: the pathogenesis of irreversible cell injury in ischemia. Am J Pathol (1981) 2.28
Biology of disease: membrane injury and calcium homeostasis in the pathogenesis of coagulative necrosis. Lab Invest (1982) 1.65
Accelerated phospholipid degradation and associated membrane dysfunction in irreversible, ischemic liver cell injury. J Biol Chem (1978) 1.64
The role of calcium in cell death. Life Sci (1981) 1.57
Ferric iron and superoxide ions are required for the killing of cultured hepatocytes by hydrogen peroxide. Evidence for the participation of hydroxyl radicals formed by an iron-catalyzed Haber-Weiss reaction. J Biol Chem (1985) 1.52
Prevention of experimental allergic encephalomyelitis by targeting nitric oxide and peroxynitrite: implications for the treatment of multiple sclerosis. Proc Natl Acad Sci U S A (1997) 1.42
Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore. J Biol Chem (1999) 1.40
Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition. J Biol Chem (1993) 1.39
tert-butyl hydroperoxide kills cultured hepatocytes by peroxidizing membrane lipids. Arch Biochem Biophys (1989) 1.37
Prevention by chlorpromazine of ischemic liver cell death. Am J Pathol (1977) 1.31
Induction of the mitochondrial permeability transition mediates the killing of HeLa cells by staurosporine. Cancer Res (2001) 1.30
The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition. J Biol Chem (1996) 1.26
Markers for gene expression in cultured cells from the nervous system. J Biol Chem (1972) 1.26
Mechanisms of the killing of cultured hepatocytes by hydrogen peroxide. Arch Biochem Biophys (1984) 1.18
Endogenous defenses against the cytotoxicity of hydrogen peroxide in cultured rat hepatocytes. J Biol Chem (1985) 1.17
Esophageal cancer prevention in zinc-deficient rats: rapid induction of apoptosis by replenishing zinc. J Natl Cancer Inst (2001) 1.14
Early, reversible plasma membrane injury in galactosamine-induced liver cell death. Am J Pathol (1975) 1.14
Endocytosis of superoxide dismutase is required in order for the enzyme to protect hepatocytes from the cytotoxicity of hydrogen peroxide. J Biol Chem (1988) 1.13
Superoxide dismutase and catalase protect cultured hepatocytes from the cytotoxicity of acetaminophen. Biochem Biophys Res Commun (1987) 1.12
Protoporphyrin IX, an endogenous ligand of the peripheral benzodiazepine receptor, potentiates induction of the mitochondrial permeability transition and the killing of cultured hepatocytes by rotenone. J Biol Chem (1994) 1.12
Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway. J Biol Chem (1999) 1.11
A simple method for decreasing the toxicity of polyethylene glycol in mammalian cell hybridization. Somatic Cell Genet (1979) 1.08
Two mechanisms by which ATP depletion potentiates induction of the mitochondrial permeability transition. Am J Physiol (1997) 1.05
Calcium-dependent and calcium-independent mechanisms of irreversible cell injury in cultured hepatocytes. J Biol Chem (1986) 1.04
A possible role for centrosome overduplication in radiation-induced cell death. Oncogene (2000) 1.04
Dissociation of intracellular lysosomal rupture from the cell death caused by silica. J Cell Biol (1980) 1.04
Toxic consequence of the abrupt depletion of glutathione in cultured rat hepatocytes. Arch Biochem Biophys (1988) 1.03
Lysosomal origin of the ferric iron required for cell killing by hydrogen peroxide. Biochem Biophys Res Commun (1985) 1.02
Autophagic degradation of protein generates a pool of ferric iron required for the killing of cultured hepatocytes by an oxidative stress. Mol Pharmacol (1990) 1.02
Ischemic myocardial cell injury. Prevention by chlorpromazine of an accelerated phospholipid degradation and associated membrane dysfunction. Am J Pathol (1979) 1.01
Dietary zinc deficiency fuels esophageal cancer development by inducing a distinct inflammatory signature. Oncogene (2011) 1.00
Reversal of ischemic mitochondrial dysfunction. J Biol Chem (1979) 1.00
Microtubule antagonists activate programmed cell death (apoptosis) in cultured rat hepatocytes. Am J Pathol (1993) 0.99
Roles for oxidative stress and poly(ADP-ribosyl)ation in the killing of cultured hepatocytes by methyl methanesulfonate. Biochem Pharmacol (1993) 0.99
Mechanisms of cell injury in the killing of cultured hepatocytes by bromobenzene. J Biol Chem (1982) 0.99
Cellular pool of transient ferric iron, chelatable by deferoxamine and distinct from ferritin, that is involved in oxidative cell injury. Mol Pharmacol (1992) 0.98
Calcium ion-dependent signalling and mitochondrial dysfunction: mitochondrial calcium uptake during hormonal stimulation in intact liver cells and its implication for the mitochondrial permeability transition. Biochim Biophys Acta (1995) 0.96
Differential effects of cycloheximide on protein and RNA synthesis as a function of dose. Biochem Biophys Res Commun (1973) 0.96
Microsomal membrane dysfunction in ischemic rat liver cells. Arch Biochem Biophys (1977) 0.95
Ca2+ depletion prevents anoxic death of hepatocytes by inhibiting mitochondrial permeability transition. Am J Physiol (1995) 0.95
D-galactosamine and acute liver cell injury. Fed Proc (1973) 0.93
Dependence of the carbon-tetrachloride--induced death of cultured hepatocytes on the extracellular calcium concentration. Am J Pathol (1981) 0.92
Increases in cytosolic calcium ion concentration can be dissociated from the killing of cultured hepatocytes by tert-butyl hydroperoxide. J Biol Chem (1991) 0.92
The biochemical pathology of liver cell necrosis. Am J Pathol (1975) 0.92
Intracellular calcium homeostasis in galactosamine-intoxicated rat liver cells. Active sequestration of calcium by microsomes and mitochondria. Arch Biochem Biophys (1977) 0.92
Mitochondrial damage as a mechanism of cell injury in the killing of cultured hepatocytes by tert-butyl hydroperoxide. Arch Biochem Biophys (1989) 0.91
Galactosamine-induced cell death in primary cultures of rat hepatocytes. Am J Pathol (1980) 0.91
Calcium dependence of phalloidin-induced liver cell death. Proc Natl Acad Sci U S A (1980) 0.91
Accelerated phospholipid degradation in anoxic rat hepatocytes. Arch Biochem Biophys (1981) 0.91
Cell proliferation and esophageal carcinogenesis in the zinc-deficient rat. Carcinogenesis (1996) 0.90
Cytochrome c-dependent activation of caspase-3 by tumor necrosis factor requires induction of the mitochondrial permeability transition. Am J Pathol (2000) 0.90
Sirolimus-induced pneumonitis complicated by pentamidine-induced phospholipidosis in a renal transplant recipient: a case report. Transplant Proc (2011) 0.89
Dissociation of the accumulation of single-strand breaks in DNA from the killing of cultured hepatocytes by an oxidative stress. Mol Pharmacol (1989) 0.88
Liposome-encapsulated superoxide dismutase prevents liver necrosis induced by acetaminophen. Am J Pathol (1990) 0.88
ATP synthase activity is required for fructose to protect cultured hepatocytes from the toxicity of cyanide. Am J Physiol (1993) 0.87
ATP depletion and loss of cell integrity in anoxic hepatocytes and silica-treated P388D1 macrophages. Am J Physiol (1985) 0.87
Structural alterations of the inner mitochondrial membrane in ischemic liver cell injury. Arch Biochem Biophys (1985) 0.87
Prevention of galactosamine-induced liver cell necrosis by uridine. Am J Pathol (1973) 0.86
Reversal of ischemic mitochondrial dysfunction. J Biol Chem (1981) 0.86
Zinc replenishment reduces esophageal cell proliferation and N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumor incidence in zinc-deficient rats. Carcinogenesis (1998) 0.86
The induction of fibrillar nucleoli in rat liver cells by D-galactosamine and their subsequent re-formation into normal nucleoli. J Ultrastruct Res (1973) 0.86
Mechanisms of hypoxic cell injury. Summary of the symposium presented at the 1990 annual meeting of the Society of Toxicology. Toxicol Appl Pharmacol (1990) 0.85
The inhibition of rat liver nuclear ribonucleic acid synthesis by galactosamine and its reversal by uridine. Lab Invest (1974) 0.85
Bronchial atresia with relapsing pulmonary infection in a middle-aged man. Respir Care (2001) 0.85
Protection by cyclosporin A of cultured hepatocytes from the toxic consequences of the loss of mitochondrial energization produced by 1-methyl-4-phenylpyridinium. Biochem Pharmacol (1992) 0.84
Oxygen-mediated cell injury in the killing of cultured hepatocytes by acetaminophen. Biochem Biophys Res Commun (1985) 0.84
Acute respiratory distress syndrome due to pulmonary involvement by neoplastic plasma cells in multiple myeloma. Thorax (2006) 0.83
The killing of cultured hepatocytes by N-acetyl-p-benzoquinone imine (NAPQI) as a model of the cytotoxicity of acetaminophen. Biochem Pharmacol (1991) 0.83
Irreversible ischemic cell injury. Prevention by chlorpromazine of the aggregation of the intramembranous particles of rat liver plasma membranes. Am J Pathol (1978) 0.83
The presence of B-cell nodules does not necessarily portend a less favorable outcome to therapy in patients with acute cellular rejection of a renal allograft. Transplant Proc (2006) 0.83
Early deregulation of the the p16ink4a-cyclin D1/cyclin-dependent kinase 4-retinoblastoma pathway in cell proliferation-driven esophageal tumorigenesis in zinc-deficient rats. Cancer Res (2000) 0.83
Mechanisms of cell injury with hepatotoxic chemicals. Pharmacol Rev (1984) 0.82
Inhibition of rat liver RNA polymerases by action of the methylating agents dimethylnitrosamine in vivo and methyl methanesulfonate in vitro. Cancer Res (1976) 0.82
Potentiation in the intact rat of the hepatotoxicity of acetaminophen by 1,3-bis(2-chloroethyl)-1-nitrosourea. Arch Biochem Biophys (1988) 0.81
Endocytosis-independent uptake of liposome-encapsulated superoxide dismutase prevents the killing of cultured hepatocytes by tert-butyl hydroperoxide. Arch Biochem Biophys (1990) 0.81
Microsomal membrane structure and function subsequent to calcium activation of an endogenous phospholipase. Arch Biochem Biophys (1980) 0.81
Phospholipid metabolism and intracellular Ca2+ homeostasis in cultured rat hepatocytes intoxicated with cyanide. Am J Physiol (1992) 0.81
Increases in the activity of the solubilized rat liver nuclear RNA polymerases following partial hepatectomy. Arch Biochem Biophys (1975) 0.80
1,3-(2-Chloroethyl)-1-nitrosourea potentiates the toxicity of acetaminophen both in the phenobarbital-induced rat and in hepatocytes cultured from such animals. Mol Pharmacol (1988) 0.80
Assessment of physiological interaction between vitamin E and vitamin C. Methods Enzymol (1999) 0.80
Protein thiol depletion and the killing of cultured hepatocytes by hydrogen peroxide. Biochem Pharmacol (1989) 0.80
Human- and mouse-inducible nitric oxide synthase promoters require activation of phosphatidylcholine-specific phospholipase C and NF-kappa B. Mol Med (1997) 0.80
Differing effects of the inhibition of poly(ADP-ribose) polymerase on the course of oxidative cell injury in hepatocytes and fibroblasts. Biochem Pharmacol (1993) 0.79
Intracellular acidosis protects cultured hepatocytes from the toxic consequences of a loss of mitochondrial energization. Arch Biochem Biophys (1989) 0.79
Oxidative cell injury in the killing of cultured hepatocytes by allyl alcohol. Arch Biochem Biophys (1988) 0.79
N-hydroxy-2-acetylaminofluorene inhibition of rat live RNA polymerases. Cancer Res (1975) 0.79
Ultrastruct pathology of phalloidin-intoxicated hepatocytes in the presence and absence of extracellular calcium. Am J Pathol (1982) 0.79
Metabolism of acetaminophen by cultured rat hepatocytes. Depletion of protein thiol groups without any loss of viability. Biochem Pharmacol (1990) 0.79
Metabolism of pyridine nucleotides in cultured rat hepatocytes intoxicated with tert-butyl hydroperoxide. Biochem Pharmacol (1992) 0.79
Effect of homologous RNA polymerase on the increase in chromatin template activity of stimulated fibroblasts. Biochem Biophys Res Commun (1972) 0.79
The antioxidant function of the physiological content of vitamin C. Mol Pharmacol (1996) 0.79
Increased sensitivity to oxidative injury in chinese hamster ovary cells stably transfected with rat liver S-adenosylmethionine synthetase cDNA. Biochem J (1996) 0.78
Alcohol-dependent liver cell necrosis in vitro: a new model. Science (1981) 0.78
Prospective comparison of helical CT and MR imaging in clinically suspected acute pulmonary embolism. J Magn Reson Imaging (1997) 0.78
Effects of vitamin E on the killing of cultured hepatocytes by tert-butyl hydroperoxide. Mol Pharmacol (1992) 0.78
Alterations in the metabolism of lipids in ischemia of the liver and kidney. J Lipid Res (1985) 0.78