Development of physical forms of unintegrated retroviral DNA in mouse spinal cord tissue during ts1-induced spongiform encephalomyelopathy: elevated levels of a novel single-stranded form in paralyzed mice.

PubWeight™: 0.79‹?›

🔗 View Article (PMC 188582)

Published in J Virol on January 01, 1995

Authors

P F Szurek1, B R Brooks

Author Affiliations

1: Neurology Service, William S. Middleton Memorial Veterans Affairs Hospital.

Articles cited by this

Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem (1983) 206.01

Nucleotide sequence of Moloney murine leukaemia virus. Nature (1981) 24.82

Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis. Biochemistry (1975) 22.00

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc Natl Acad Sci U S A (1989) 18.26

Integration of murine leukemia virus DNA depends on mitosis. EMBO J (1993) 7.62

Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol Cell Biol (1990) 5.81

Incompletely reverse-transcribed human immunodeficiency virus type 1 genomes in quiescent cells can function as intermediates in the retroviral life cycle. J Virol (1992) 5.78

Transport of cationic amino acids by the mouse ecotropic retrovirus receptor. Nature (1991) 5.40

Partial reverse transcripts in virions from human immunodeficiency and murine leukemia viruses. J Virol (1992) 4.72

FVB/N: an inbred mouse strain preferable for transgenic analyses. Proc Natl Acad Sci U S A (1991) 4.29

Cellular functions are required for the synthesis and integration of avian sarcoma virus-specific DNA. Cell (1977) 4.06

Retrovirus variation and reverse transcription: abnormal strand transfers result in retrovirus genetic variation. Proc Natl Acad Sci U S A (1993) 4.04

Restriction endonuclease cleavage of linear and closed circular murine leukemia viral DNAs: discovery of a smaller circular form. Cell (1979) 4.04

Toward an understanding of the molecular mechanisms of physiological cell death. Proc Natl Acad Sci U S A (1993) 3.80

Identification of DNA fragments carrying ecotropic proviruses of AKR mice. Proc Natl Acad Sci U S A (1979) 3.64

Correlation between cell killing and massive second-round superinfection by members of some subgroups of avian leukosis virus. J Virol (1980) 3.53

Exonuclease III of Escherichia coli K-12, an AP endonuclease. Methods Enzymol (1980) 3.50

High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients. Nature (1990) 3.28

Identification of ecotropic proviral sequences in inbred mouse strains with a cloned subgenomic DNA fragment. Proc Natl Acad Sci U S A (1980) 3.19

Quantitative separation of murine leukemia virus proteins by reversed-phase high-pressure liquid chromatography reveals newly described gag and env cleavage products. J Virol (1984) 2.91

Evidence for helper independent murine sarcoma virus. I. Segregation of replication-defective and transformation-defective viruses. Virology (1973) 2.67

Rapid, selective procedure for isolation of spontaneous temperature-sensitive mutants of Moloney leukemia virus. Virology (1973) 2.51

Mechanisms of cell killing/cytopathic effects by nonhuman retroviruses. Rev Infect Dis (1988) 2.47

Synthesis and circularization of N- and B-tropic retroviral DNA Fv-1 permissive and restrictive mouse cells. Proc Natl Acad Sci U S A (1980) 2.45

Site-specific cleavage of single-stranded DNA by a Hemophilus restriction endonuclease. Proc Natl Acad Sci U S A (1975) 2.32

Nucleotide sequencing of an apparent proviral copy of env mRNA defines determinants of expression of the mouse mammary tumor virus env gene. J Virol (1983) 2.20

Cloning and characterization of an envelope-specific probe from xenotropic murine leukemia proviral DNA. J Virol (1982) 2.09

Specific hybridization probes demonstrate fewer xenotropic than mink cell focus-forming murine leukemia virus env-related sequences in DNAs from inbred laboratory mice. J Virol (1986) 2.08

The role of envelope glycoprotein processing in murine leukemia virus infection. J Virol (1987) 2.06

Retroviruses and embryogenesis: microinjection of Moloney leukemia virus into midgestation mouse embryos. Cell (1980) 2.05

The steps of reverse transcription of Drosophila mobile dispersed genetic elements and U3-R-U5 structure of their LTRs. Cell (1986) 1.91

Viral genetic determinants of T-cell killing and immunodeficiency disease induction by the feline leukemia virus FeLV-FAIDS. J Virol (1991) 1.83

Comparison of Moloney murine leukemia virus mutation rate with the fidelity of its reverse transcriptase in vitro. J Biol Chem (1992) 1.73

Identification of point mutations in the envelope gene of Moloney murine leukemia virus TB temperature-sensitive paralytogenic mutant ts1: molecular determinants for neurovirulence. J Virol (1988) 1.70

A Val-25-to-Ile substitution in the envelope precursor polyprotein, gPr80env, is responsible for the temperature sensitivity, inefficient processing of gPr80env, and neurovirulence of ts1, a mutant of Moloney murine leukemia virus TB. J Virol (1990) 1.57

A group of temperature-sensitive mutants of Moloney leukemia virus which is defective in cleavage of env precursor polypeptide in infected cells also induces hind-limb paralysis in newborn CFW/D mice. Virology (1983) 1.50

Pathogenesis of the slow disease of the central nervous system associated with wild mouse virus. III. Role of input virus and MCF recombinants in disease. Virology (1983) 1.42

Lower limb paralysis induced in mice by a temperature-sensitive mutant of Moloney leukemia virus. J Natl Cancer Inst (1977) 1.40

A 1.6-kilobase-pair fragment in the genome of the ts1 mutant of Moloney murine leukemia virus TB that is associated with temperature sensitivity, nonprocessing of Pr80env, and paralytogenesis. J Virol (1985) 1.29

Molecular cloning of two paralytogenic, temperature-sensitive mutants, ts1 and ts7, and the parental wild-type Moloney murine leukemia virus. J Virol (1985) 1.28

Correlation of specific virus-astrocyte interactions and cytopathic effects induced by ts1, a neurovirulent mutant of Moloney murine leukemia virus. J Virol (1993) 1.25

ts1, a Paralytogenic mutant of Moloney murine leukemia virus TB, has an enhanced ability to replicate in the central nervous system and primary nerve cell culture. J Virol (1985) 1.21

Noninflammatory spongiform polioencephalomyelopathy caused by a neurotropic temperature-sensitive mutant of Moloney murine leukemia virus TB. Am J Pathol (1986) 1.19

Minus-strand DNA is present within murine type C ecotropic retroviruses prior to infection. J Virol (1993) 1.14

Murine retroviral neurovirulence correlates with an enhanced ability ofvirus to infect selectively, replicate in, and activate resident microglial cells. Am J Pathol (1991) 1.11

Isolation and mapping of cDNA hybridization probes specific for ecotropic and nonecotropic murine leukemia proviruses. Virology (1983) 1.09

Site-directed mutagenesis of the codon for Ile-25 in gPr80env alters the neurovirulence of ts1, a mutant of Moloney murine leukemia virus TB. J Virol (1990) 1.08

Host genes conferring resistance to a central nervous system disease induced by a polytropic recombinant Friend murine retrovirus. J Virol (1990) 1.07

The reduced virulence of the thymotropic Moloney murine leukemia virus derivative MoMuLV-TB is mapped to 11 mutations within the U3 region of the long terminal repeat. J Virol (1989) 0.99

Splice acceptor site for the env message of Moloney murine leukemia virus. J Virol (1987) 0.98

Distinct superinfection interference properties yet similar receptor utilization by cytopathic and noncytopathic feline leukemia viruses. J Virol (1993) 0.98

Neurological disease induced in transgenic mice expressing the env gene of the Cas-Br-E murine retrovirus. Proc Natl Acad Sci U S A (1993) 0.95

Temporal central and peripheral nervous system changes induced by a paralytogenic mutant of Moloney murine leukemia virus TB. Lab Invest (1993) 0.93

The pathogenesis of murine retroviral infection of the central nervous system. Brain Pathol (1993) 0.91

Non-oncogenic infectious agents associated with experimental tumors. Prog Exp Tumor Res (1965) 0.91

Temporal lymphoreticular changes caused by ts1, a paralytogenic mutant of Moloney murine leukemia virus TB. Lab Invest (1992) 0.87

Simplified filter paper sandwich blot provides rapid, background-free northern blots. Biotechniques (1992) 0.87

Neuronal loss in a lower motor neuron disease induced by a murine retrovirus. Can J Neurol Sci (1991) 0.87

Homologous superinfection of both producer and nonproducer HIV-infected cells is blocked at a late retrotranscription step. Virology (1993) 0.84

Analysis of a temperature-sensitive mutation affecting the integration protein of Moloney murine leukemia virus. Virology (1993) 0.81

Sequence-specific toxicity of transfected retroviral DNA. Exp Cell Res (1991) 0.78

Expression of major histocompatibility complex antigens and serum neutralizing antibody in murine retroviral encephalitis. J Neuropathol Exp Neurol (1993) 0.76

Articles by these authors

(truncated to the top 100)

Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. The Copolymer 1 Multiple Sclerosis Study Group. Neurology (1995) 8.63

Neuroreality I. Dedicated demolition of the Decade of the Brain: the genuine threat to neurologic research from the animal radical right. The American Academy of Neurology Animal Studies Subcommittee. Neurology (1995) 3.77

Langevin dynamics of peptides: the frictional dependence of isomerization rates of N-acetylalanyl-N'-methylamide. Biopolymers (1992) 2.86

The effects of truncating long-range forces on protein dynamics. Proteins (1989) 2.67

Extended use of glatiramer acetate (Copaxone) is well tolerated and maintains its clinical effect on multiple sclerosis relapse rate and degree of disability. Copolymer 1 Multiple Sclerosis Study Group. Neurology (1998) 2.52

Protein hydration elucidated by molecular dynamics simulation. Proc Natl Acad Sci U S A (1993) 2.26

Dynamics of DNA oligomers. J Biomol Struct Dyn (1983) 2.08

Progressive multifocal leukoencephalopathy. Neurol Clin (1984) 1.92

Theoretically determined three-dimensional structures for amphipathic segments of the HIV-1 gp41 envelope protein. AIDS Res Hum Retroviruses (1989) 1.89

Practice parameter: the care of the patient with amyotrophic lateral sclerosis (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology: ALS Practice Parameters Task Force. Neurology (1999) 1.83

Failure to detect enterovirus in the spinal cord of ALS patients using a sensitive RT-PCR method. Neurology (2004) 1.83

A 500 ps molecular dynamics simulation study of interleukin-1 beta in water. Correlation with nuclear magnetic resonance spectroscopy and crystallography. J Mol Biol (1992) 1.77

Temperature dependence of dynamics of hydrated myoglobin. Comparison of force field calculations with neutron scattering data. J Mol Biol (1990) 1.73

Spongiform polioencephalomyelopathy caused by a murine retrovirus. I. Pathogenesis of infection in newborn mice. Lab Invest (1980) 1.48

Spongiform polioencephalomyelopathy caused by a murine retrovirus. II. Ultrastructural localization of virus replication and spongiform changes in the central nervous system. Neuropathol Appl Neurobiol (1982) 1.33

Murine neurotropic retrovirus spongiform polioencephalomyelopathy: acceleration of disease by virus inoculum concentration. Infect Immun (1979) 1.31

Molecular dynamics simulations of native and substrate-bound lysozyme. A study of the average structures and atomic fluctuations. J Mol Biol (1986) 1.25

Correlation of specific virus-astrocyte interactions and cytopathic effects induced by ts1, a neurovirulent mutant of Moloney murine leukemia virus. J Virol (1993) 1.25

Sustained clinical benefits of glatiramer acetate in relapsing multiple sclerosis patients observed for 6 years. Copolymer 1 Multiple Sclerosis Study Group. Mult Scler (2000) 1.23

Consensus guidelines for the design and implementation of clinical trials in ALS. World Federation of Neurology committee on Research. J Neurol Sci (1999) 1.22

Molecular dynamics simulations of human rhinovirus and an antiviral compound. Biophys J (2001) 1.22

Hydrated myoglobin's anharmonic fluctuations are not primarily due to dihedral transitions. Proc Natl Acad Sci U S A (1996) 1.22

Interaction of DNA with bifunctional aldehydes. Eur J Biochem (1968) 1.15

Hypoglossal, trigeminal, and facial motoneuron involvement in amyotrophic lateral sclerosis. Neurology (1988) 1.13

Home ventilation for amyotrophic lateral sclerosis patients: outcomes, costs, and patient, family, and physician attitudes. Neurology (1993) 1.11

Structural brain correlates of emotional disorder in multiple sclerosis. Brain (1986) 1.09

Absorption mode two-dimensional NOE spectroscopy of exchangeable protons in oligonucleotides. FEBS Lett (1987) 1.06

Transition from B to Z DNA: contribution of internal fluctuations to the configurational entropy difference. Science (1985) 1.03

A diagnostic index of active demyelination: myelin basic protein in cerebrospinal fluid. Ann Neurol (1980) 1.03

Multiple orofacial indices in amyotrophic lateral sclerosis. J Speech Hear Res (1993) 1.03

Amyotrophic lateral sclerosis. A case-control study following detection of a cluster in a small Wisconsin community. Arch Neurol (1990) 1.01

Norepinephrine and gamma-aminobutyric acid in amyotrophic lateral sclerosis. Neurology (1980) 1.01

Disease activity and emotional state in multiple sclerosis. Ann Neurol (1983) 1.01

Emotional disturbance in multiple sclerosis patients: validity of the General Health Questionnaire (GHQ). Psychol Med (1981) 1.01

Linkage analysis in familial amyotrophic lateral sclerosis. Neurology (1989) 1.00

Positioning of positively charged residues in the V3 loop correlates with HIV type 1 syncytium-inducing phenotype. AIDS Res Hum Retroviruses (1996) 1.00

Multiple tactile maps in the human cerebellum. Neuroreport (2001) 0.99

Acute posterior multifocal placoid pigment epitheliopathy associated with cerebral vasculitis. J Clin Neuroophthalmol (1988) 0.98

Oligoclonal IgG bands in cerebrospinal fluid in various neurological diseases. Ann Neurol (1983) 0.97

A three-dimensional model of an anti-lysozyme antibody. J Mol Biol (1987) 0.97

Quantitative description of the dysarthria in women with amyotrophic lateral sclerosis. J Speech Hear Res (1992) 0.96

Cerebrospinal fluid norepinephrine alterations during electrical stimulation of cerebellar, cerebral surfaces in epileptic patients. Neurology (1977) 0.95

Cerebrospinal fluid GABA reductions in seizure patients evoked by cerebellar surface stimulation. J Neurosurg (1977) 0.95

Measles virus vaccination of measles seropositive individuals suppresses lymphocyte proliferation and chemotactic factor production. Clin Immunol Immunopathol (1981) 0.94

Models of delta-hemolysin membrane channels and crystal structures. Proteins (1990) 0.94

Spinal seizures following intravenous contrast in a patients with a cord AVM. Ann Neurol (1981) 0.93

Subcortical reorganization in amyotrophic lateral sclerosis. Exp Brain Res (2006) 0.92

The ALS patient care database: goals, design, and early results. ALS C.A.R.E. Study Group. Neurology (2000) 0.92

Cerebrospinal fluid acid-base and lactate changes after seizures in unanesthetized man. I. Idiopathic seizures. Neurology (1975) 0.92

Cerebrospinal fluid myelin basic protein in hydrocephalus. J Neurosurg (1983) 0.92

Cerebrospinal-fluid lymphocyte populations and immune complexes in active multiple sclerosis. Lancet (1980) 0.91

Impairment of speech intelligibility in men with amyotrophic lateral sclerosis. J Speech Hear Disord (1990) 0.89

Quantitative assessment of motor fatigue in amyotrophic lateral sclerosis. J Neurol Sci (2001) 0.86

Alteration from T- to B-cell tropism reduces thymic atrophy and cytocidal effects in thymocytes but not neurovirulence induced by ts1, a mutant of Moloney murine leukemia virus TB. Proc Natl Acad Sci U S A (1991) 0.86

Metabolism-based transformation of myoglobin to an oxidase by BrCCl3 and molecular modeling of the oxidase form. J Biol Chem (1993) 0.86

Catalytic mechanism of aldose reductase studied by the combined potentials of quantum mechanics and molecular mechanics. Biophys Chem (1998) 0.85

Speech deterioration in amyotrophic lateral sclerosis: a case study. J Speech Hear Res (1991) 0.85

Glatiramer acetate (Copaxone): comparison of continuous versus delayed therapy in a six-year organized multiple sclerosis trial. Mult Scler (2003) 0.83

Patient teaching manuals improve retention of treatment information--a controlled clinical trial in multiple sclerosis. J Neurosci Nurs (1986) 0.83

Normal modes for large molecules with arbitrary link constraints in the mobile block Hessian approach. J Chem Phys (2009) 0.83

Intravenous thyrotropin-releasing hormone in patients with amyotrophic lateral sclerosis. Dose-response and randomized concurrent placebo-controlled pilot studies. Neurol Clin (1987) 0.82

Theoretical studies of relaxation of a monomeric subunit of HIV-1 protease in water using molecular dynamics. Proteins (1993) 0.82

The rigid spine syndrome due to acid maltase deficiency. Muscle Nerve (1997) 0.81

Pulmonary effects of thyrotropin-releasing hormone in amyotrophic lateral sclerosis. Lancet (1984) 0.81

Dissociation between mechanical and myoelectrical manifestation of muscle fatigue in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord (2004) 0.81

Effect of bovine serum albumin on mitochondrial respiration in the brain and liver of mice and rats. Bull Exp Biol Med (2010) 0.81

CSF viral antibodies. Evaluation in amyotrophic lateral sclerosis and late-onset postpoliomyelitis progressive muscular atrophy. Arch Neurol (1979) 0.81

Solution conformations of the B-loop fragments of human transforming growth factor alpha and epidermal growth factor by 1H nuclear magnetic resonance and restrained molecular dynamics. Proc Natl Acad Sci U S A (1990) 0.81

Relationship between norepinephrine in blood and cerebrospinal fluid in the presence of a blood-cerebrospinal fluid barrier for norepinephrine. J Neurochem (1977) 0.81

Physiologic and metabolic response to progressive and prolonged exercise in amyotrophic lateral sclerosis. Neurology (1987) 0.80

Practice parameter: The care of the patient with amyotrophic lateral sclerosis (An evidence-based review). Muscle Nerve (1999) 0.80

CuZnSOD and MnSOD immunoreactivity in brain stem motor neurons from amyotrophic lateral sclerosis patients. Acta Neuropathol (1998) 0.80

Transient areflexia and quadriplegia following metrizamide myelography. Ann Neurol (1982) 0.80

Theoretically determined three-dimensional structure for the repeating tetrapeptide unit of the circumsporozoite coat protein of the malaria parasite Plasmodium falciparum. Proc Natl Acad Sci U S A (1987) 0.80

Cellular immunity and hepatitis-associated-antigen liver disease. Lancet (1972) 0.79

Adult-onset acid maltase deficiency. Morphologic and biochemical abnormalities reproduced in in cultured muscle. N Engl J Med (1976) 0.79

Age-dependent in vitro restriction of mouse neurotropic retrovirus replication in central nervous system-derived cells from susceptible Fv-1nn mice. Trans Am Neurol Assoc (1981) 0.79

Epidemic heat stroke in a midwest community: risk factors, neurological complications and sequelae. Wis Med J (1997) 0.79

Murine leukemia virus induced central nervous system diseases. Leukemia (1992) 0.78

Molecular mechanics and antibody binding in the structural analysis of polycyclic aromatic hydrocarbon-diol-epoxide--DNA adducts. Carcinogenesis (1990) 0.78

Spinal cord metabolic changes in murine retrovirus-induced motor neuron disease. Brain Res Bull (1983) 0.78

Computer simulations of a tumor surface octapeptide epitope. Biopolymers (1989) 0.77

ts1-Induced spongiform encephalomyelopathy: physical forms of high-mobility DNA in spinal cord tissues of paralyzed mice are products of premature termination of reverse transcription. J Virol (1996) 0.77

Conformational states of a TT mismatch from molecular dynamics simulation of duplex d (CGCGATTCGCG). Biopolymers (1992) 0.77

Molecular modeling of nucleic acid structure: electrostatics and solvation. Curr Protoc Nucleic Acid Chem (2001) 0.76

Molecular modeling of nucleic acid structure: setup and analysis. Curr Protoc Nucleic Acid Chem (2001) 0.76

Synthesis of virus-specific high-mobility DNA after temperature upshift of SC-1 cells chronically infected with moloney murine leukemia virus mutant ts1. J Virol (2000) 0.76

Zidovudine [AZT] myotoxicity: quantitative separation of AZT effects on proliferation and differentiation of muscle cells in vitro. Lack of myotoxicity potentiation by retrovirus. Neurotoxicology (1999) 0.76

Role of muscular exercise in amyotrophic lateral sclerosis. Neurol Clin (1987) 0.76

Extended use of glatiramer acetate (Copaxone) is well tolerated and maintains its clinical effect on multiple sclerosis relapse rate and degree of disability. 1998 [classical article]. Neurology (2001) 0.76

Molecular modeling of nucleic acid structure. Curr Protoc Nucleic Acid Chem (2001) 0.75

Dropped head syndrome. Neurology (1997) 0.75

Molecular modeling of nucleic acid structure: energy and sampling. Curr Protoc Nucleic Acid Chem (2001) 0.75

Demonstration of thyrotropin-releasing hormone immunoreactivity in neurons of the mouse spinal dorsal horn. J Neurosci (1986) 0.75

"Mineral transporter" therapy for multiple sclerosis complicated by bacterial endocarditis. Ann Neurol (1986) 0.75

Issues in clinical trial design. II: Selection of end point measures. Neurology (1996) 0.75

CD8 and CD4 T cell-mediated polymyositis complicating the HTLV-1 associated myelopathy. Quantitative evaluation of corticosteroid treatment. Acta Neurol Scand (1996) 0.75

Faculty development activities. Nurs Outlook (1981) 0.75

Thyrotropin-releasing hormone (TRH) degradation in NIH:N mouse cerebral cortex and spinal cord. Neurosci Lett (1986) 0.75

Relationship between cerebrospinal fluid norepinephrine and blood pressure in neurologic patients. Clin Exp Hypertens (1980) 0.75