Published in J Clin Invest on December 01, 1994
Male reproductive health and environmental xenoestrogens. Environ Health Perspect (1996) 4.11
Research needs for the risk assessment of health and environmental effects of endocrine disruptors: a report of the U.S. EPA-sponsored workshop. Environ Health Perspect (1996) 3.34
Milk consumption and acne in teenaged boys. J Am Acad Dermatol (2008) 2.33
Challenges to the measurement of estradiol: an endocrine society position statement. J Clin Endocrinol Metab (2013) 2.11
Sexual maturation in relation to polychlorinated aromatic hydrocarbons: Sharpe and Skakkebaek's hypothesis revisited. Environ Health Perspect (2002) 2.03
Growth hormone plus childhood low-dose estrogen in Turner's syndrome. N Engl J Med (2011) 1.82
Evaluation of a recombinant yeast cell estrogen screening assay. Environ Health Perspect (1997) 1.65
Comparison of life-stage-dependent internal dosimetry for bisphenol A, ethinyl estradiol, a reference estrogen, and endogenous estradiol to test an estrogenic mode of action in Sprague Dawley rats. Toxicol Sci (2014) 1.59
Hormone changes in peripubertal girls. J Clin Endocrinol Metab (2014) 1.49
Effects of low-dose estrogen replacement during childhood on pubertal development and gonadotropin concentrations in patients with Turner syndrome: results of a randomized, double-blind, placebo-controlled clinical trial. J Clin Endocrinol Metab (2014) 1.42
Longitudinal development of secondary sexual characteristics in girls and boys between ages 91/2 and 151/2 years. Arch Pediatr Adolesc Med (2010) 1.26
Anastrozole increases predicted adult height of short adolescent males treated with growth hormone: a randomized, placebo-controlled, multicenter trial for one to three years. J Clin Endocrinol Metab (2007) 1.11
Association between bisphenol A exposure and body mass index in Chinese school children: a cross-sectional study. Environ Health (2012) 1.07
Assaying estrogenicity by quantitating the expression levels of endogenous estrogen-regulated genes. Environ Health Perspect (2000) 1.03
Bone age advancement in prepubertal children with obesity and premature adrenarche: possible potentiating factors. Obesity (Silver Spring) (2011) 1.00
Impaired plasma phospholipids and relative amounts of essential polyunsaturated fatty acids in autistic patients from Saudi Arabia. Lipids Health Dis (2011) 0.97
Evo-devo of human adolescence: beyond disease models of early puberty. BMC Med (2013) 0.96
Metabolic effects of oral versus transdermal 17β-estradiol (E₂): a randomized clinical trial in girls with Turner syndrome. J Clin Endocrinol Metab (2013) 0.90
Plasma kisspeptin levels in girls with premature thelarche. J Clin Res Pediatr Endocrinol (2012) 0.87
Pharmacokinetics and pharmacodynamics of oral and transdermal 17β estradiol in girls with Turner syndrome. J Clin Endocrinol Metab (2011) 0.86
Turner syndrome and sexual differentiation of the brain: implications for understanding male-biased neurodevelopmental disorders. J Neurodev Disord (2011) 0.85
Prepubertal girls with premature adrenarche have greater bone mineral content and density than controls. J Clin Endocrinol Metab (2001) 0.85
Emotional symptoms in children: The effect of maternal depression, life events, and COMT genotype. Am J Med Genet B Neuropsychiatr Genet (2009) 0.85
Comparison of detection of normal puberty in girls by a hormonal sleep test and a gonadotropin-releasing hormone agonist test. J Clin Endocrinol Metab (2013) 0.84
Serum oestrogen receptor alpha and beta bioactivity are independently associated with breast cancer: a proof of principle study. Br J Cancer (2009) 0.84
An information-theoretic analysis of genetics, gender and age in cancer patients. PLoS One (2008) 0.83
Sex and inflammation in respiratory diseases: a clinical viewpoint. Biol Sex Differ (2013) 0.82
Modeling the interaction of binary and ternary mixtures of estradiol with bisphenol A and bisphenol AF in an in vitro estrogen-mediated transcriptional activation assay (T47D-KBluc). Toxicol Sci (2010) 0.82
Investigation of sex differences in the expression of RORA and its transcriptional targets in the brain as a potential contributor to the sex bias in autism. Mol Autism (2015) 0.80
Steroid assays in paediatric endocrinology. J Clin Res Pediatr Endocrinol (2010) 0.79
Genotype-phenotype relationship in Japanese patients with congenital central hypoventilation syndrome. J Hum Genet (2015) 0.78
Gender and obesity modify the impact of salt intake on blood pressure in children. Pediatr Nephrol (2015) 0.77
Maternal High Estradiol Exposure is Associated with Elevated Thyroxine and Pax8 in Mouse Offspring. Sci Rep (2016) 0.75
A new beginning for estrogen physiology. J Clin Invest (1994) 0.75
Evaluating Weight Status and Sex as Moderators of the Association of Serum Leptin with Bone Mineral Density in Children and Adolescents . Horm Res Paediatr (2017) 0.75
Prepubertal ultra-low-dose estrogen therapy is associated with healthier lipid profile than conventional estrogen replacement for pubertal induction in adolescent girls with Turner syndrome: preliminary results. J Endocrinol Invest (2017) 0.75
Longer duration of obesity is associated with a reduction in urinary angiotensinogen in prepubertal children. Pediatr Nephrol (2017) 0.75
Variations in pattern of pubertal changes in girls. Arch Dis Child (1969) 23.35
Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol Cell Biol (1984) 6.23
Reduced levels of hsp90 compromise steroid receptor action in vivo. Nature (1990) 5.23
Variant human breast tumor estrogen receptor with constitutive transcriptional activity. Cancer Res (1991) 1.92
A microtiter plate-based system for the semiautomated growth and assay of bacterial cells for beta-galactosidase activity. Anal Biochem (1989) 1.77
Protease B of Saccharomyces cerevisiae: isolation and regulation of the PRB1 structural gene. Genetics (1987) 1.64
Changes in the pituitary-testicular system with age. Clin Endocrinol (Oxf) (1976) 1.43
Steroid and gonadotropin levels in women during the peri-menopausal years. Maturitas (1986) 1.38
Plasma adrenal and gonadal sex steroids in human pubertal development. J Clin Endocrinol Metab (1976) 1.37
Estradiol radioimmunoassay without chromatography: procedure, validation and normal values. J Clin Endocrinol Metab (1974) 1.36
Estrone sulfate: production rate and metabolism in man. J Clin Invest (1972) 1.20
Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast. Mol Endocrinol (1992) 1.19
Studies on human sexual development. II. Fetal and maternal serum gonadotropin and sex steroid concentrations. J Clin Endocrinol Metab (1974) 1.19
A preliminary study of the effect of estrogen dose on growth in Turner's syndrome. N Engl J Med (1983) 1.16
The measurement of estrone sulfate in plasma. Steroids (1971) 1.13
Experimental basis for selecting the optimal conditions for quantitative fluorometry of natural estrogens. Endocrinology (1950) 1.06
High level expression of biologically active estrogen receptor in Saccharomyces cerevisiae. J Steroid Biochem Mol Biol (1991) 1.03
Hypothalamic-pituitary-gonadal relationships in man from birth to puberty. Clin Endocrinol (Oxf) (1976) 1.03
Oestrone, oestradiol-17beta and oestriol levels in human foetal plasma during gestation and at term. J Endocrinol (1974) 0.98
Treatment of familial male precocious puberty with spironolactone, testolactone, and deslorelin. J Clin Endocrinol Metab (1993) 0.98
The use of 2-3-5-triphenyltetrazolium chloride in the biological assay of oestrogens. J Endocrinol (1960) 0.96
Radioimmunoassay of estradiol-17beta without chromatography. J Clin Endocrinol Metab (1974) 0.95
The efficacy of CGS 20267 in suppressing estrogen biosynthesis in patients with advanced stage breast cancer. J Steroid Biochem Mol Biol (1993) 0.92
The pattern of gonadotropin and estradiol secretion in exaggerated thelarche. Acta Endocrinol (Copenh) (1993) 0.92
Short term, low dose estradiol accelerates ulnar growth in boys. J Clin Endocrinol Metab (1985) 0.91
Estradiol-17-beta and estrone: studies on their binding to rabbit uterine cytosol and their concentration in plasma. Steroids (1971) 0.90
Differential changes in serum concentrations of androgens and estrogens (in relation with cortisol) in postmenopausal women with acute illness. J Clin Endocrinol Metab (1993) 0.89
Unconjugated estrogens in the perinatal period. Pediatr Res (1973) 0.88
The mitogenic action of oestrogens in the vaginal epithelium of the ovariectomized mouse. J Endocrinol (1960) 0.86
The effects of synthetic estrogens on the metabolic clearance and production rates of estrone and estradiol. Steroids (1974) 0.84
The effect of short term treatment with growth hormone and ethinyl estradiol on lower leg growth rate in girls with Turner's syndrome. J Clin Endocrinol Metab (1988) 0.84
Radioimmunoassay of steroids in biological fluids. J Steroid Biochem (1976) 0.84
Relationship between urine and plasma estrogen ratios. Cancer Res (1978) 0.83
Growth-promoting effect of growth hormone and low dose ethinyl estradiol in girls with Turner's syndrome. J Clin Endocrinol Metab (1990) 0.83
Plasma estrogens in childhood and puberty under physiologic and pathologic conditions. Pediatr Res (1973) 0.83
Monthly gonadotropin cycles in premenarcheal girls. Science (1975) 0.80
Estrogen assays using the rat uterus. Endocrinology (1954) 0.80
Progressive increase in nonsex hormone-binding globulin-bound testosterone and estradiol from infancy to late prepuberty in girls. J Clin Endocrinol Metab (1988) 0.78
Cost-effectiveness analysis in a setting of budget constraints--is it equitable? N Engl J Med (1996) 4.13
The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens. Endocrinology (1999) 3.67
Neuroendocrine tumors of the lung with proposed criteria for large-cell neuroendocrine carcinoma. An ultrastructural, immunohistochemical, and flow cytometric study of 35 cases. Am J Surg Pathol (1991) 3.59
Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proc Natl Acad Sci U S A (1988) 3.53
Cancer risk after a hospital discharge diagnosis of endometriosis. Am J Obstet Gynecol (1997) 3.10
Petrosal sinus sampling with and without corticotropin-releasing hormone for the differential diagnosis of Cushing's syndrome. N Engl J Med (1991) 2.93
Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. Mol Endocrinol (1993) 2.89
Molecular cloning of complementary DNA encoding the avian receptor for vitamin D. Science (1987) 2.71
A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty. Nature (1993) 2.68
Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions. Mol Endocrinol (1994) 2.62
The human estrogen receptor-alpha is a ubiquitinated protein whose stability is affected differentially by agonists, antagonists, and selective estrogen receptor modulators. J Biol Chem (2001) 2.45
Increasing cancer risk in younger birth cohorts in Sweden. Lancet (1993) 2.39
The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. Cell (1992) 2.37
Bisphenol A interacts with the estrogen receptor alpha in a distinct manner from estradiol. Mol Cell Endocrinol (1998) 2.18
Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta. Mol Cell Biol (1999) 2.13
Growth and neuroendocrine dysfunction in children with acquired immunodeficiency syndrome. J Pediatr (1990) 2.07
Cognitive processes and the decisions of some parents to forego pertussis vaccination for their children. J Clin Epidemiol (1996) 2.04
Effect of carbenoxolone on the plasma renin activity and hypothalamic-pituitary-adrenal axis in congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Clin Endocrinol (Oxf) (1999) 2.03
The metyrapone and dexamethasone suppression tests for the differential diagnosis of the adrenocorticotropin-dependent Cushing syndrome: a comparison. Ann Intern Med (1994) 2.00
Prophylactic red-cell transfusions in pregnant patients with sickle cell disease. A randomized cooperative study. N Engl J Med (1988) 1.97
Variant human breast tumor estrogen receptor with constitutive transcriptional activity. Cancer Res (1991) 1.92
The hypotonic upper airway in obstructive sleep apnea: role of structures and neuromuscular activity. Am J Respir Crit Care Med (1998) 1.90
Order of magnitude smaller limit on the electric dipole moment of the electron. Science (2013) 1.89
Body size in different periods of life and breast cancer risk in post-menopausal women. Int J Cancer (1998) 1.86
Peptide antagonists of the human estrogen receptor. Science (1999) 1.86
The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding. Mol Cell Biol (2000) 1.83
The effects of estrogen priming and puberty on the growth hormone response to standardized treadmill exercise and arginine-insulin in normal girls and boys. J Clin Endocrinol Metab (1994) 1.79
Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers. J Biol Chem (1995) 1.78
Cushing's syndrome in children and adolescents. Presentation, diagnosis, and therapy. N Engl J Med (1994) 1.78
Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay. Toxicol Appl Pharmacol (1997) 1.75
A randomized, cross-over trial of once-daily versus twice-daily parathyroid hormone 1-34 in treatment of hypoparathyroidism. J Clin Endocrinol Metab (1998) 1.73
Oral contraceptives and breast cancer: final report of an epidemiological study. Br J Cancer (1983) 1.71
Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1. J Biol Chem (2000) 1.70
High fluid intake increases urine free cortisol excretion in normal subjects. J Clin Endocrinol Metab (1998) 1.70
Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors. Mol Cell Biol (1996) 1.70
Rsp5 ubiquitin-protein ligase mediates DNA damage-induced degradation of the large subunit of RNA polymerase II in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.66
Evaluation of a recombinant yeast cell estrogen screening assay. Environ Health Perspect (1997) 1.65
Risk factors for colorectal cancer in patients with ulcerative colitis: a case-control study. Gastroenterology (1994) 1.64
Body size and risk of breast cancer. Am J Epidemiol (1997) 1.63
The nuclear corepressors NCoR and SMRT are key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor. Mol Cell Biol (1998) 1.61
Long-term hormone replacement therapy and risk of breast cancer in postmenopausal women. Am J Epidemiol (1995) 1.59
Synthetic human parathyroid hormone 1-34 vs calcitriol and calcium in the treatment of hypoparathyroidism. JAMA (1996) 1.56
Bacterial proteins that mediate the association of a defined subset of T cell receptor:CD4 complexes with class II MHC. J Immunol (1990) 1.54
The inclusion of patient testimonials in decision aids: effects on treatment choices. Med Decis Making (2001) 1.54
Analysis of repetitive sequence elements containing tRNA-like sequences. Nucleic Acids Res (1985) 1.53
Comparative analyses of mechanistic differences among antiestrogens. Endocrinology (1999) 1.52
Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta. Proc Natl Acad Sci U S A (1999) 1.52
Migratory arrest of gonadotropin-releasing hormone neurons in transgenic mice. Proc Natl Acad Sci U S A (1991) 1.48
The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells. Mol Cell Biol (1994) 1.48
Omission bias and pertussis vaccination. Med Decis Making (1994) 1.48
Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium. Proc Natl Acad Sci U S A (1999) 1.46
Absence of growth hormone effects on cognitive function in girls with Turner syndrome. J Clin Endocrinol Metab (1997) 1.44
Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3. Proc Natl Acad Sci U S A (1990) 1.42
Effects of estrogen on growth plate senescence and epiphyseal fusion. Proc Natl Acad Sci U S A (2001) 1.41
Radioimmunoguided surgery benefits for recurrent colorectal cancer. Ann Surg Oncol (1997) 1.39
Circumventing tamoxifen resistance in breast cancers using antiestrogens that induce unique conformational changes in the estrogen receptor. Cancer Res (2001) 1.38
Insecticide-induced lupus erythematosus. Int J Dermatol (1994) 1.38
Gonadotropin secretory dynamics during puberty in normal girls and boys. J Clin Endocrinol Metab (1990) 1.38
Regulation of growth plate chondrogenesis by bone morphogenetic protein-2. Endocrinology (2001) 1.37
The corticotropin-releasing factor stimulation test. An aid in the evaluation of patients with Cushing's syndrome. N Engl J Med (1984) 1.36
Organochlorine compounds in relation to breast cancer, endometrial cancer, and endometriosis: an assessment of the biological and epidemiological evidence. Crit Rev Toxicol (1995) 1.35
Effect of 3-amino-1,2,4-triazole on the stimulation of hepatic microsomal heme synthesis and induction of hepatic microsomal oxidases produced by phenobarbital. Mol Pharmacol (1969) 1.35
The colonoscopic miss rate and true one-year recurrence of colorectal neoplastic polyps. Polyp Prevention Study Group. Am J Gastroenterol (1999) 1.33
Inhibition of estrogen receptor action by a naturally occurring variant in human breast tumors. Cancer Res (1992) 1.30
The A and B isoforms of the human progesterone receptor: two functionally different transcription factors encoded by a single gene. Recent Prog Horm Res (1999) 1.30
Differential interaction of the methoxychlor metabolite 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane with estrogen receptors alpha and beta. Endocrinology (1999) 1.29
Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: structure-activity studies. Mol Pharmacol (2000) 1.28
Organochlorine compounds and estrogen-related cancers in women. Cancer Causes Control (1995) 1.27
The role of thrombin in preterm parturition. Am J Obstet Gynecol (2001) 1.26
Reproductive factors and the risk of brain tumors: a population-based study in Sweden. Int J Cancer (1997) 1.25
Nutrients and gastric cancer risk. A population-based case-control study in Sweden. Int J Cancer (1994) 1.25
BRCA1 expression is not directly responsive to estrogen. Oncogene (1997) 1.24
Energy, nutrient intake and prostate cancer risk: a population-based case-control study in Sweden. Int J Cancer (1996) 1.24
Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators. J Steroid Biochem Mol Biol (1994) 1.24
Hormone-dependent interaction between the amino- and carboxyl-terminal domains of progesterone receptor in vitro and in vivo. Mol Endocrinol (1999) 1.23
Enhanced protein synthesis in a cell-free system from hypertrophied skeletal muscle. Science (1967) 1.23
Effects of fibroblast growth factor-2 on longitudinal bone growth. Endocrinology (1998) 1.22
Mutations in the Ca(2+)-sensing receptor gene cause autosomal dominant and sporadic hypoparathyroidism. Hum Mol Genet (1996) 1.21
Early life risk factors for prostate cancer: a population-based case-control study in Sweden. Cancer Epidemiol Biomarkers Prev (1995) 1.20
Management of the ectopic ACTH syndrome due to thoracic carcinoids. Ann Thorac Surg (1990) 1.20
Transactivation functions facilitate the disruption of chromatin structure by estrogen receptor derivatives in vivo. J Biol Chem (1991) 1.20
Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast. Mol Endocrinol (1992) 1.19
A single midnight serum cortisol measurement distinguishes Cushing's syndrome from pseudo-Cushing states. J Clin Endocrinol Metab (1998) 1.19
Aortic homograft replacement of the mitral valve in sickle cell trait. J Thorac Cardiovasc Surg (1970) 1.18
Premature thelarche and central precocious puberty: the relationship between clinical presentation and the gonadotropin response to luteinizing hormone-releasing hormone. J Clin Endocrinol Metab (1988) 1.18
The NIH experience with precocious puberty: diagnostic subgroups and response to short-term luteinizing hormone releasing hormone analogue therapy. J Pediatr (1986) 1.18
Early-life risk indicators of gastric cancer. A population-based case-control study in Sweden. Int J Cancer (1994) 1.17
Enhancement of estrogen receptor transcriptional activity by the coactivator GRIP-1 highlights the role of activation function 2 in determining estrogen receptor pharmacology. J Biol Chem (1998) 1.17
Therapeutic use of pituitary desensitization with a long-acting lhrh agonist: a potential new treatment for idiopathic precocious puberty. J Clin Endocrinol Metab (1981) 1.17
Short-term treatment of idiopathic precocious puberty with a long-acting analogue of luteinizing hormone-releasing hormone. A preliminary report. N Engl J Med (1981) 1.16
Clinical reasoning and cognitive processes. Med Decis Making (1988) 1.16
Estrogenic activity of a dieldrin/toxaphene mixture in the mouse uterus, MCF-7 human breast cancer cells, and yeast-based estrogen receptor assays: no apparent synergism. Endocrinology (1997) 1.16
Ectopic adrenocorticotropic hormone syndrome: localization studies in 28 patients. Radiology (1989) 1.16
A preliminary study of the effect of estrogen dose on growth in Turner's syndrome. N Engl J Med (1983) 1.16
The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins. J Clin Endocrinol Metab (1992) 1.15
Risk of breast cancer in relation to lifetime alcohol consumption. J Natl Cancer Inst (1995) 1.14
Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers. Proc Natl Acad Sci U S A (1991) 1.14
Mapping and characterization of the functional domains responsible for the differential activity of the A and B isoforms of the human progesterone receptor. J Biol Chem (1997) 1.14