Published in Eur Heart J on February 01, 1994
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med (2001) 20.20
Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Stat Med (1998) 19.07
A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med (2001) 9.75
Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer: the ICON4/AGO-OVAR-2.2 trial. Lancet (2003) 8.88
Effect of prone positioning on the survival of patients with acute respiratory failure. N Engl J Med (2001) 8.74
A trial of goal-oriented hemodynamic therapy in critically ill patients. SvO2 Collaborative Group. N Engl J Med (1995) 7.88
Randomised clinical trials in general practice: lessons from a failure. BMJ (1991) 5.35
Oxidative DNA damage in peripheral leukocytes of mild cognitive impairment and AD patients. Neurobiol Aging (2005) 4.88
The impact of blood glucose self-monitoring on metabolic control and quality of life in type 2 diabetic patients: an urgent need for better educational strategies. Diabetes Care (2001) 3.67
Cytotoxic and hormonal treatment for metastatic breast cancer: a systematic review of published randomized trials involving 31,510 women. J Clin Oncol (1998) 3.65
A randomized clinical trial of high-intensity warfarin vs. conventional antithrombotic therapy for the prevention of recurrent thrombosis in patients with the antiphospholipid syndrome (WAPS). J Thromb Haemost (2005) 3.47
Health services: an Italian market. Lancet (1996) 3.43
Randomized clinical trials on medical treatment of glaucoma. Are they appropriate to guide clinical practice? Arch Ophthalmol (1993) 2.44
The threshold for prophylactic platelet transfusions in adults with acute myeloid leukemia. Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto. N Engl J Med (1997) 2.41
APOE and Alzheimer disease: a major gene with semi-dominant inheritance. Mol Psychiatry (2011) 2.31
Quality, evolution, and clinical implications of randomized, controlled trials on the treatment of lung cancer. A lost opportunity for meta-analysis. JAMA (1989) 2.18
The EMIP project. European Myocardial Infarction Project. Eur Heart J (2000) 2.15
Extended-spectrum beta-lactamases in enterobacteriaceae in Buenos Aires, Argentina, public hospitals. Antimicrob Agents Chemother (2003) 2.09
The teaching and organisation of clinical pharmacology in European medical schools (W.H.O. Working Group on Clinical Pharmacology). Eur J Clin Pharmacol (1990) 2.07
Has clinical pharmacology lost its way? Lancet (1984) 2.02
Randomized controlled trial of single-agent paclitaxel versus cyclophosphamide, doxorubicin, and cisplatin in patients with recurrent ovarian cancer who responded to first-line platinum-based regimens. J Clin Oncol (2002) 2.00
Clinical pharmacokinetics of diazepam. Clin Pharmacokinet (1978) 1.99
T-lymphocyte maturation abnormalities in uninfected newborns and children with vertical exposure to HIV. Blood (2000) 1.94
Human pharmacokinetics and bioavailability of temazepam administered in soft gelatin capsules. Eur J Clin Pharmacol (1977) 1.94
"Pap" smear and the risk of cervical neoplasia: quantitative estimates from a case-control study. Lancet (1984) 1.87
Age-related increase in mortality among patients with first myocardial infarctions treated with thrombolysis. The Investigators of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI-2). N Engl J Med (1993) 1.81
ACE inhibitor use in patients with myocardial infarction. Summary of evidence from clinical trials. Circulation (1995) 1.75
North-South twinning in paediatric haemato-oncology: the La Mascota programme, Nicaragua. Lancet (1998) 1.75
Effectiveness of antibiotic prophylaxis in critically ill adult patients: systematic review of randomised controlled trials. BMJ (1998) 1.75
Prevalence and prognostic significance of ventricular arrhythmias after acute myocardial infarction in the fibrinolytic era. GISSI-2 results. Circulation (1993) 1.74
Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patients. Crit Care Med (2001) 1.73
Non-typhoid Salmonella spp. resistant to cefotaxime. J Antimicrob Chemother (1995) 1.71
Postoperative pain treatment SIAARTI Recommendations 2010. Short version. Minerva Anestesiol (2010) 1.70
Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local viral replication. AIDS (1998) 1.70
Effect of the ACE inhibitor lisinopril on mortality in diabetic patients with acute myocardial infarction: data from the GISSI-3 study. Circulation (1997) 1.68
Cefotaxime-hydrolysing beta lactamases in Morganella morganii. Eur J Clin Microbiol Infect Dis (1999) 1.67
Assessment of absolute risk of death after myocardial infarction by use of multiple-risk-factor assessment equations: GISSI-Prevenzione mortality risk chart. Eur Heart J (2001) 1.66
Feasibility of a large prospective study in general practice: an Italian experience. Gruppo di Studio sulla Pressione Arteriosa nell'Anziano. Br Med J (Clin Res Ed) (1987) 1.65
Oestrogens and obesity as risk factors for endometrial cancer in Italy. Int J Epidemiol (1982) 1.64
Pharmacokinetics of N-demethyldiazepam in patients suffering from insomnia and treated with nortriptyline. Br J Clin Pharmacol (1975) 1.63
Epidermal growth factor receptor overexpression correlates with a poor prognosis in completely resected non-small-cell lung cancer. Ann Oncol (2004) 1.62
Self-monitoring of blood glucose in non-insulin-treated diabetic patients: a longitudinal evaluation of its impact on metabolic control. Diabet Med (2005) 1.59
Epidemiology of post-infarction risk stratification strategies in a country with a low volume of revascularization procedures. GISSI-Prognosis Investigators. Eur Heart J (1998) 1.56
Risk factors for myocardial infarction in young women. Am J Epidemiol (1987) 1.55
N-desmethyldiazepam and amylobarbitone sodium as hypnotics in anxious patients. Plasma levels, clinical efficacy and residual effects. Psychopharmacologia (1975) 1.54
Differential diagnosis and management of focal ground-glass opacities. Eur Respir J (2008) 1.54
Clinical pharmacokinetics of amiodarone. Clin Pharmacokinet (1984) 1.53
Lp(a) in hypertensive patients. J Hum Hypertens (1998) 1.51
Incessant ovulation and ovarian cancer: a critical approach. Int J Epidemiol (1983) 1.51
Neuroendocrine differentiation in human prostate tissue: is it detectable and treatable? BJU Int (2003) 1.50
Second-generation clinical pharmacology. Lancet (1986) 1.49
The long-term prognostic significance of repeated blood pressure measurements in the elderly: SPAA (Studio sulla Pressione Arteriosa nell'Anziano) 10-year follow-up. Arch Intern Med (1999) 1.48
A meta-analysis of trials on aldose reductase inhibitors in diabetic peripheral neuropathy. The Italian Study Group. The St. Vincent Declaration. Diabet Med (1996) 1.46
Randomised study of systematic lymphadenectomy in patients with epithelial ovarian cancer macroscopically confined to the pelvis. Br J Cancer (2006) 1.46
Vinorelbine and prednisone in frail elderly patients with intermediate-high grade non-Hodgkin's lymphomas. Ann Oncol (2005) 1.45
Aspirin does not interact with ACE inhibitors when both are given early after acute myocardial infarction: results of the GISSI-3 Trial. Heart Dis (2001) 1.45
The contribution of sublingual immunotherapy to the achievement of control in birch-related mild persistent asthma: a real-life randomised trial. Allergol Immunopathol (Madr) (2012) 1.41
The impact of cancer treatment guidelines on actual practice in Italian general hospitals: the case of ovarian cancer. Ann Oncol (1990) 1.40
Dosimetric considerations on multiple arc stereotaxic radiotherapy. Radiother Oncol (1988) 1.39
Caffeine disposition after oral doses. Clin Pharmacol Ther (1982) 1.39
Semisynthetic resorbable materials from hyaluronan esterification. Biomaterials (1998) 1.38
Survey on the treatment of non-small-cell lung cancer in Italy. Ann Oncol (2000) 1.38
Benzodiazepines: clinical pharmacology and therapeutic use. Drugs (1980) 1.36
Antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving intensive care. Cochrane Database Syst Rev (2004) 1.34
Incidence and prognostic significance of atrial fibrillation in acute myocardial infarction: the GISSI-3 data. Heart (2001) 1.32
Solid variant of aneurysmal bone cyst. Cancer (1993) 1.30
Clinical pharmacology and primary health care in Europe--a gap to bridge. The WHO Working Group on Clinical Pharmacology in Europe. Eur J Clin Pharmacol (1990) 1.30
Unusual multiresistant Vibrio cholerae O1 El Tor in Argentina. Lancet (1993) 1.30
Information on drug use in pregnancy from the Viewpoint Regional Drug Information Centre. Eur J Clin Pharmacol (1988) 1.28
Long-term follow-up of isolated optic neuritis: the risk of developing multiple sclerosis, its outcome, and the prognostic role of paraclinical tests. J Neurol (1999) 1.27
Recommendations for airway control and difficult airway management. Minerva Anestesiol (2005) 1.24
First-line treatment for advanced ovarian cancer: paclitaxel, platinum and the evidence. Br J Cancer (2002) 1.24
Internet for clinical trials: past, present, and future. Control Clin Trials (1999) 1.21
Conservative surgery for stage I ovarian carcinoma in women of childbearing age. Br J Obstet Gynaecol (1997) 1.21
Early onset pneumonia: a multicenter study in intensive care units. Intensive Care Med (1987) 1.20
First-line chemotherapy for advanced ovarian cancer: paclitaxel, cisplatin and the evidence. Br J Cancer (1998) 1.19
Impact of recent legislative bills regarding clinical research on Italian ethics committee activity. J Med Ethics (2008) 1.18
Risk factors for endometrial cancer at different ages. J Natl Cancer Inst (1984) 1.18
Expression levels of vascular endothelial growth factor, matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinases 1 and 2 in the plasma of patients with ovarian carcinoma. Eur J Cancer (2003) 1.18