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1 Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA. Proc Natl Acad Sci U S A 1983 14.09
2 SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat. Mol Cell Biol 1988 12.84
3 A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature 1994 9.31
4 Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease. Proc Natl Acad Sci U S A 1984 4.97
5 Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1. EMBO J 1986 4.58
6 Functional activation of the long terminal repeat of human T-cell leukemia virus type I by a trans-acting factor. Proc Natl Acad Sci U S A 1985 4.24
7 Transcriptional (p40x) and post-transcriptional (p27x-III) regulators are required for the expression and replication of human T-cell leukemia virus type I genes. Proc Natl Acad Sci U S A 1987 4.10
8 Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering. Cell 1987 4.10
9 Direct evidence that p40x of human T-cell leukemia virus type I is a trans-acting transcriptional activator. EMBO J 1986 3.86
10 Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules. J Biol Chem 1997 3.74
11 A transcriptional enhancer sequence of HTLV-I is responsible for trans-activation mediated by p40 chi HTLV-I. EMBO J 1986 3.53
12 Post-transcriptional regulator (rex) of HTLV-1 initiates expression of viral structural proteins but suppresses expression of regulatory proteins. EMBO J 1988 3.45
13 p27x-III and p21x-III, proteins encoded by the pX sequence of human T-cell leukemia virus type I. Proc Natl Acad Sci U S A 1985 3.34
14 Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration. J Cell Biol 2001 3.32
15 Human adult T-cell leukemia virus: molecular cloning of the provirus DNA and the unique terminal structure. Proc Natl Acad Sci U S A 1982 3.19
16 Expression of the pX gene of HTLV-I: general splicing mechanism in the HTLV family. Science 1985 3.18
17 The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis. Cell 2001 2.97
18 Nonspecific integration of the HTLV provirus genome into adult T-cell leukaemia cells. Nature 1984 2.78
19 Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. Oncogene 1993 2.55
20 Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma. Cancer 2001 2.51
21 Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion. Proc Natl Acad Sci U S A 1997 2.35
22 Interaction of HTLV-1 Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxes. Genes Dev 1992 2.23
23 Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion. EMBO J 2001 2.23
24 T-cell activation signals and human T-cell leukemia virus type I-encoded p40x protein activate the mouse granulocyte-macrophage colony-stimulating factor gene through a common DNA element. Mol Cell Biol 1988 2.08
25 A single species of pX mRNA of human T-cell leukemia virus type I encodes trans-activator p40x and two other phosphoproteins. J Virol 1986 2.04
26 Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family. J Biol Chem 1995 2.01
27 Identification of a protein (p40x) encoded by a unique sequence pX of human T-cell leukemia virus type I. Gan 1984 1.97
28 Activation of T cell-derived lymphokine genes in T cells and fibroblasts: effects of human T cell leukemia virus type I p40x protein and bovine papilloma virus encoded E2 protein. Nucleic Acids Res 1988 1.86
29 Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis. Cancer Res 2001 1.85
30 The C-terminal region of membrane type matrix metalloproteinase is a functional transmembrane domain required for pro-gelatinase A activation. J Biol Chem 1995 1.84
31 The p40x of human T-cell leukemia virus type I is a trans-acting activator of viral gene transcription. Jpn J Cancer Res 1985 1.83
32 Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences. J Biol Chem 1996 1.81
33 v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines. J Biol Chem 1993 1.76
34 Identification of a suppressor sequence for DNA replication in the replication origin region of the Bacillus subtilis chromosome. Proc Natl Acad Sci U S A 1982 1.75
35 Secondary structure of the human T-cell leukemia virus type 1 rex-responsive element is essential for rex regulation of RNA processing and transport of unspliced RNAs. J Virol 1990 1.75
36 Expression of membrane-type matrix metalloproteinase in human gastric carcinomas. Cancer Res 1995 1.72
37 Sequence homology of the simian retrovirus genome with human T-cell leukemia virus type I. Virology 1985 1.72
38 The second pX product p27 chi-III of HTLV-1 is required for gag gene expression. FEBS Lett 1986 1.72
39 Cytoplasmic tail-dependent internalization of membrane-type 1 matrix metalloproteinase is important for its invasion-promoting activity. J Cell Biol 2001 1.71
40 HTLV-1 Tax induces expression of various immediate early serum responsive genes. Oncogene 1991 1.71
41 Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2. FEBS Lett 1996 1.63
42 Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas. Cancer Res 1997 1.60
43 TIMP-2 promotes activation of progelatinase A by membrane-type 1 matrix metalloproteinase immobilized on agarose beads. J Biol Chem 1998 1.59
44 Identification of gag and env gene products of human T-cell leukemia virus (HTLV). Virology 1984 1.53
45 Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis. Int J Cancer 1995 1.48
46 Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human urothelial carcinomas. J Urol 1998 1.48
47 Retrovirus terminology. Science 1983 1.47
48 Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone resorption. Lab Invest 1995 1.46
49 Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and is secreted in a complex with tissue inhibitor of metalloproteinases 2. Cancer Res 1996 1.45
50 The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated urokinase and collagenase genes in response to epidermal growth factor. Int J Cancer 1998 1.44
51 Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors. Am J Pathol 1999 1.42
52 Transcriptional activation of the matrix metalloproteinase-9 gene in an H-ras and v-myc transformed rat embryo cell line. Oncogene 1997 1.42
53 Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression. J Immunol 1989 1.42
54 Intermolecular autolytic cleavage can contribute to the activation of progelatinase A by cell membranes. J Biol Chem 1995 1.41
55 Expression of genes encoding type IV collagen-degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells. Oncogene 1992 1.40
56 Cell surface binding and activation of gelatinase A induced by expression of membrane-type-1-matrix metalloproteinase (MT1-MMP). FEBS Lett 1996 1.37
57 Induction and stimulation of 92-kDa gelatinase/type IV collagenase production in osteosarcoma and fibrosarcoma cell lines by tumor necrosis factor alpha. Biochem Biophys Res Commun 1990 1.36
58 Overexpression of membrane-type matrix metalloproteinase-1 gene induces mammary gland abnormalities and adenocarcinoma in transgenic mice. Cancer Res 2001 1.36
59 Membrane-type matrix metalloproteinases (MT-MMPs) in tumor metastasis. J Biochem 1996 1.35
60 Ribosomal RNA genes in the replication origin region of Bacillus subtilis chromosome. Nature 1982 1.35
61 Structure and function of the region of the replication origin of the Bacillus subtilis chromosome. I. Isolation and characterization of plasmids containing the origin region. Mol Gen Genet 1981 1.35
62 Claudin promotes activation of pro-matrix metalloproteinase-2 mediated by membrane-type matrix metalloproteinases. J Biol Chem 2001 1.32
63 MT-MMP, the cell surface activator of proMMP-2 (pro-gelatinase A), is expressed with its substrate in mouse tissue during embryogenesis. J Cell Sci 1996 1.32
64 Structure of the region of the replication origin of the Bacillus subtilis chromosome. Nature 1979 1.32
65 Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma. Lab Invest 1997 1.32
66 Membrane type 4 matrix metalloproteinase (MT4-MMP, MMP-17) is a glycosylphosphatidylinositol-anchored proteinase. J Biol Chem 1999 1.31
67 Replication origin region of Bacillus subtilis chromosome contains two rRNA operons. J Bacteriol 1983 1.30
68 Recent advances in the molecular biology of HTLV-1: trans-activation of viral and cellular genes. Annu Rev Immunol 1987 1.29
69 Increased expression of matrix metalloproteinase-II in experimental liver fibrosis in rats. Hepatology 1995 1.26
70 Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro. Cancer Res 1996 1.26
71 Regulation of collagenase-3 expression in human breast carcinomas is mediated by stromal-epithelial cell interactions. Cancer Res 1997 1.25
72 Enhanced production of matrix metalloproteinases and activation of matrix metalloproteinase 2 (gelatinase A) in human gastric carcinomas. Int J Cancer 1996 1.25
73 Association of the pX gene product of human T-cell leukemia virus type-I with nucleus. Virology 1985 1.21
74 Effect of novobiocin on initiation of DNA replication in Bacillus subtilis. Nature 1979 1.20
75 Membrane-type 6 matrix metalloproteinase (MT6-MMP, MMP-25) is the second glycosyl-phosphatidyl inositol (GPI)-anchored MMP. FEBS Lett 2000 1.19
76 Thrombin induces the activation of progelatinase A in vascular endothelial cells. Physiologic regulation of angiogenesis. J Biol Chem 1995 1.19
77 HTLV-1 Tax has distinct but overlapping domains for transcriptional activation and for enhancer specificity. Oncogene 1991 1.19
78 MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells. Clin Exp Metastasis 1997 1.19
79 Monoclonal integration of HTLV-I proviral DNA in patients with strongyloidiasis. Int J Cancer 1987 1.18
80 Regulation of matrix metalloproteinase-2 (MMP-2) by hepatocyte growth factor/scatter factor (HGF/SF) in human glioma cells: HGF/SF enhances MMP-2 expression and activation accompanying up-regulation of membrane type-1 MMP. Int J Cancer 1999 1.18
81 Transformation of Madin-Darby canine kidney (MDCK) epithelial cells by Epstein-Barr virus latent membrane protein 1 (LMP1) induces expression of Ets1 and invasive growth. Oncogene 2000 1.18
82 Initiation of DNA replication in Bacillus subtilis. V. Role of DNA gyrase and superhelical structure in initiation. Mol Gen Genet 1981 1.13
83 A novel fibrinolytic enzyme extracted from the earthworm, Lumbricus rubellus. Jpn J Physiol 1991 1.13
84 Front-cell-specific expression of membrane-type 1 matrix metalloproteinase and gelatinase A during cohort migration of colon carcinoma cells induced by hepatocyte growth factor/scatter factor. Cancer Res 2000 1.13
85 Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas. Cancer Res 1999 1.11
86 Identification of envelope glycoprotein encoded by env gene of human T-cell leukemia virus. Gan 1983 1.10
87 Organization of the replication-origin region of the Bacillus subtilis chromosome. Cold Spring Harb Symp Quant Biol 1979 1.10
88 Proteolytic activation of the precursor of membrane type 1 matrix metalloproteinase by human plasmin. A possible cell surface activator. FEBS Lett 1997 1.10
89 Membrane type 1-matrix metalloproteinase is involved in the formation of hepatocyte growth factor/scatter factor-induced branching tubules in madin-darby canine kidney epithelial cells. Biochem Biophys Res Commun 1998 1.10
90 MT1-MMP and MMP-2 mRNA expression in human ovarian tumors: possible implications for the role of desmoplastic fibroblasts. Hum Pathol 1998 1.09
91 Processing of a precursor of 72-kilodalton type IV collagenase/gelatinase A by a recombinant membrane-type 1 matrix metalloproteinase. Cancer Res 1996 1.08
92 New collagenolytic enzymes/cascade identified at the pannus-hard tissue junction in rheumatoid arthritis: destruction from above. Matrix Biol 1998 1.08
93 Role of tissue inhibitor of metalloproteinases-2 (TIMP-2) in regulation of pro-gelatinase A activation catalyzed by membrane-type matrix metalloproteinase-1 (MT1-MMP) in human cancer cells. J Biochem 1998 1.08
94 Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in rheumatoid synovium. Lab Invest 2000 1.07
95 Ursolic acid-induced down-regulation of MMP-9 gene is mediated through the nuclear translocation of glucocorticoid receptor in HT1080 human fibrosarcoma cells. Oncogene 1998 1.06
96 Dual expression of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase in fibrotic human livers. Hepatology 1997 1.06
97 Increased expression of membrane type 1-matrix metalloproteinase in head and neck carcinoma. Cancer 1997 1.06
98 Envelope proteins of human T-cell leukemia virus: expression in Escherichia coli and its application to studies of env gene functions. Proc Natl Acad Sci U S A 1984 1.06
99 Human T-cell leukemia virus type I is a member of the African subtype of simian viruses (STLV). Virology 1986 1.05
100 Anti-invasive activity of ursolic acid correlates with the reduced expression of matrix metalloproteinase-9 (MMP-9) in HT1080 human fibrosarcoma cells. Cancer Res 1996 1.04
101 Serum response factor has functional roles both in indirect binding to the CArG box and in the transcriptional activation function of human T-cell leukemia virus type I Tax. J Virol 1994 1.03
102 Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay. Cancer Res 1996 1.03
103 Structure and function of the region of the replication origin of the Bacillus subtilis chromosome. II. Identification of the essential regions for inhibitory functions shown by the DNA segment containing the replication origin. Mol Gen Genet 1981 1.02
104 Nucleotide sequence of the protease-coding region in an infectious DNA of simian retrovirus (STLV) of the HTLV-I family. Virology 1986 1.02
105 Complex regulation of membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation by concanavalin A in MDA-MB-231 human breast cancer cells. Cancer Res 1995 1.02
106 Matrix metalloproteinases and tissue inhibitor of metalloproteinase-2 in fetal rabbit lung. Am J Physiol Lung Cell Mol Physiol 2000 1.02
107 Enhanced tumor growth and invasiveness in vivo by a carboxyl-terminal fragment of alpha1-proteinase inhibitor generated by matrix metalloproteinases: a possible modulatory role in natural killer cytotoxicity. Am J Pathol 1999 1.02
108 Membrane-type matrix metalloproteinase-1(MT1-MTP) gene is overexpressed in highly invasive hepatocellular carcinomas. J Hepatol 1998 1.01
109 HTLV type I (U. S. isolate) and ATLV (Japanese isolate) are the same species of human retrovirus. Virology 1984 1.01
110 Detection and characterization of simian retroviruses homologous to human T-cell leukemia virus type I. Virology 1984 1.01
111 Induction of M(r) 92,000 type IV collagenase expression in a squamous cell carcinoma cell line by fibroblasts. Cancer Res 1995 1.01
112 Human T-cell leukemia virus type 1 Tax activates transcription of the human fra-1 gene through multiple cis elements responsive to transmembrane signals. J Virol 1993 1.01
113 The detection of human T cell leukemia virus proviral DNA and its application for classification and diagnosis of T cell malignancy. Blood 1984 1.01
114 Retrovirus from human T-cell leukemia virus type I-associated myelopathy is the same strain as a prototype human T-cell leukemia virus type I. Arch Neurol 1990 1.00
115 Membrane-type matrix metalloproteinases (MT-MMPs) in cell invasion. Thromb Haemost 1997 1.00
116 Ets-related protein E1A-F can activate three different matrix metalloproteinase gene promoters. Oncogene 1995 1.00
117 Tissue inhibitor of metalloproteinase 1 is a negative regulator of the metastatic ability of a human gastric cancer cell line, KKLS, in the chick embryo. Cancer Res 1993 0.99
118 Characterization of a truncated recombinant form of human membrane type 3 matrix metalloproteinase. Eur J Biochem 1999 0.99
119 Cloning of three Caenorhabditis elegans genes potentially encoding novel matrix metalloproteinases. Gene 1998 0.98
120 Activation of matrix metalloproteinase-2 in human breast cancer cells overexpressing cyclooxygenase-1 or -2. FEBS Lett 1999 0.98
121 White matter microglia produce membrane-type matrix metalloprotease, an activator of gelatinase A, in human brain tissues. Acta Neuropathol 1995 0.97
122 Membrane-type 5 matrix metalloproteinase is expressed in differentiated neurons and regulates axonal growth. Cell Growth Differ 2001 0.97
123 Expression of membrane-type 1 matrix metalloproteinase and activation of progelatinase A in human osteoarthritic cartilage. Am J Pathol 1997 0.97
124 Matrix metalloproteinase 9 (gelatinase B) is expressed in multinucleated giant cells of human giant cell tumor of bone and is associated with vascular invasion. Am J Pathol 1996 0.96
125 Thymic atrophy characteristic in transgenic mice that harbor pX genes of human T-cell leukemia virus type I. J Virol 1989 0.96
126 Differentiation-dependent expression of gelatinase B/matrix metalloproteinase-9 in trophoblast cells. Cell Tissue Res 1999 0.95
127 Initiation of DNA replication in Bacillus subtilis. IV. The effect of an intercalating dye, ethidium bromide. Mol Gen Genet 1980 0.94
128 Significance of membrane type 1 matrix metalloproteinase expression in breast cancer. Jpn J Cancer Res 1999 0.94
129 Expression of 72 kDa type IV collagenase and invasion activity of human glioma cells. Clin Exp Metastasis 1994 0.93
130 Effects of zinc L-carnosine on gastric mucosal and cell damage caused by ethanol in rats. Correlation with endogenous prostaglandin E2. Dig Dis Sci 1990 0.93
131 Gastroprokinetic activity of nizatidine, a new H2-receptor antagonist, and its possible mechanism of action in dogs and rats. J Pharmacol Exp Ther 1993 0.92
132 Induction of membrane-type matrix metalloproteinase 1 (MT1-MMP) expression in human fibroblasts by breast adenocarcinoma cells. Clin Exp Metastasis 1997 0.92
133 Inhibition of metastasis in human gastric cancer cells transfected with tissue inhibitor of metalloproteinase 1 gene in nude mice. Cancer 1996 0.92
134 Transformation of epithelial Madin-Darby canine kidney cells with p60(v-src) induces expression of membrane-type 1 matrix metalloproteinase and invasiveness. Cancer Res 1998 0.92
135 Production of membrane-type matrix metalloproteinase-1 (MT-MMP-1) in early human placenta. A possible role in placental implantation? J Histochem Cytochem 1998 0.92
136 Expression of laminin 5-γ2 chain in cutaneous squamous cell carcinoma and its role in tumour invasion. Br J Cancer 2011 0.91
137 Calcium influx inhibits MT1-MMP processing and blocks MMP-2 activation. FEBS Lett 1997 0.91
138 Furin-independent pathway of membrane type 1-matrix metalloproteinase activation in rabbit dermal fibroblasts. J Biol Chem 1999 0.90
139 Membrane-type 1 MMP (MMP-14) cleaves at three sites in the aggrecan interglobular domain. FEBS Lett 1998 0.90
140 Transient increase of intracellular cAMP by heat shock initiates the suppression of MT1-MMP production in tumor cells. Ann N Y Acad Sci 1999 0.90
141 Expression of type-IV collagenases in human tumor cell lines that can form liver colonies in chick embryos. Int J Cancer 1994 0.89
142 Dual over-expression pattern of membrane-type metalloproteinase-1 in cancer and stromal cells in human gastrointestinal carcinoma revealed by in situ hybridization and immunoelectron microscopy. Int J Cancer 1996 0.88
143 Suppression of matrix metalloproteinase-3 synthesis by interleukin-4 in human articular chondrocytes. J Rheumatol 1997 0.88
144 Isolation of a mouse MT2-MMP gene from a lung cDNA library and identification of its product. FEBS Lett 1997 0.88
145 Tax proteins of human T-cell leukemia virus type 1 and 2 induce expression of the gene encoding erythroid-potentiating activity (tissue inhibitor of metalloproteinases-1, TIMP-1). J Biol Chem 1994 0.88
146 Polyclonal integration of HTLV-I proviral DNA in lymphocytes from HTLV-I seropositive individuals: an intermediate state between the healthy carrier state and smouldering ATL. Br J Haematol 1988 0.87
147 MT-MMP expression and localisation in human lung and breast cancers. Virchows Arch 1996 0.87
148 Tyrosine phosphorylation mediates ConA-induced membrane type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in MDA-MB-231 human breast carcinoma cells. Cancer Res 1997 0.86
149 Selective activation of the proto-oncogene c-jun promoter by the transforming protein v-Rel. Oncogene 1996 0.86
150 Cell-line specific activation of SV40 transcriptional enhancer by p40tax of HTLV-1. Jpn J Cancer Res 1988 0.86
151 Molecular mechanisms of regulation of HTLV-1 gene expression and its association with leukemogenesis. Genome 1989 0.86
152 Two distinct regions form a functional activation domain of the HTLV-1 trans-activator Tax1. Oncogene 1994 0.85
153 Heat shock-mediated transient increase in intracellular 3',5'-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation. Clin Exp Metastasis 2000 0.85
154 Identification of the Tax interaction region of serum response factor that mediates the aberrant induction of immediate early genes through CArG boxes by HTLV-I Tax. Oncogene 1995 0.85
155 Molecular biology of human T-cell leukemia virus associated with adult T-cell leukemia. Curr Top Microbiol Immunol 1985 0.84
156 Expression and localization of membrane type matrix metalloproteinase-1 (MT1-MMP) in trophoblast cells of cultured mouse blastocysts and ectoplacental cones. Placenta 1998 0.84
157 Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis. Clin Exp Metastasis 2000 0.83
158 Stimulation of the 92-kD type IV collagenase promoter and enzyme expression in human melanoma cells. Invasion Metastasis 1993 0.83
159 Cloning of a human gene potentially encoding a novel matrix metalloproteinase having a C-terminal transmembrane domain. Gene 1995 0.82
160 v-Rel activates the proto-oncogene c-Jun promoter: a correlation with its transforming activity. Leukemia 1997 0.82
161 Human membrane type-2 matrix metalloproteinase is defective in cell-associated activation of progelatinase A. Biochem Biophys Res Commun 2000 0.82
162 Calmodulin antagonists increase the expression of membrane-type-1 matrix metalloproteinase in human uterine cervical fibroblasts. Eur J Biochem 1998 0.81
163 Human membrane type-4 matrix metalloproteinase (MT4-MMP) is encoded by a novel major transcript: isolation of complementary DNA clones for human and mouse mt4-mmp transcripts. FEBS Lett 1999 0.81
164 Different metastatic potentials of ras- and src-transformed BALB/c 3T3 A31 variant cells. Mol Carcinog 1996 0.81
165 Overexpression of tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in metastatic MDCK cells transformed by v-src. Clin Exp Metastasis 1999 0.81
166 Expression of membrane-type matrix metalloproteinase-1 in human pancreatic adenocarcinomas. J Cancer Res Clin Oncol 1998 0.81
167 [Adult T-cell leukemia virus (ATLV or HTLV) proviral DNA for the classification of T-cell malignancies]. Rinsho Ketsueki 1984 0.81
168 Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts. Br J Cancer 1999 0.80
169 Expression of c-fos gene inhibits proteoglycan synthesis in transfected chondrocyte. FEBS Lett 1996 0.80
170 Adult T-cell leukemia-like disease in monkey naturally infected with simian retrovirus related to human T-cell leukemia virus type I. Jpn J Cancer Res 1985 0.80
171 Tumor cell contact mediated transcriptional activation of the fibroblast matrix metalloproteinase-9 gene: involvement of multiple transcription factors including Ets and an alternating purine-pyrimidine repeat. Clin Exp Metastasis 1998 0.80
172 Expression of the membrane-type 3 matrix metalloproteinase (MT3-MMP) in human brain tissues. Acta Neuropathol 1998 0.80
173 Epstein-Barr virus BZLF1 transactivator is a negative regulator of Jun. J Virol 1992 0.80
174 Immunohistochemical study of MT-MMP tissue status in gastric carcinoma and correlation with survival analyzed by univariate and multivariate analysis. Oncol Rep 1998 0.79
175 Shedding of membrane type 1 matrix metalloproteinase in a human breast carcinoma cell line. Jpn J Cancer Res 1999 0.79
176 Effect of Z-103 on compound 48/80-induced gastric lesions in rats. Scand J Gastroenterol Suppl 1989 0.79
177 Expression and localization of matrix metalloproteinases (MT1-MMP, MMP-2) and tissue inhibitor of metalloproteinase-2 (TIMP-2) during synepitheliochorial placentation of goats (Capra hircus). Placenta 2004 0.79
178 Effects of indomethacin on the production of matrix metalloproteinase-3 and tissue inhibitor of metalloproteinases-1 by human articular chondrocytes. J Rheumatol 1996 0.79
179 Ras pathway is required for the activation of MMP-2 secretion and for the invasion of src-transformed 3Y1. Oncogene 1999 0.79
180 Clinical aspects of adult T-cell leukemia/lymphoma. Curr Top Microbiol Immunol 1985 0.79
181 Purification and refolding of recombinant human proMMP-7 (pro-matrilysin) expressed in Escherichia coli and its characterization. J Biochem 1996 0.79
182 Activation of metalloproteinase-2 by membrane type metalloproteinase expressed on human mesangial cell membrane. Contrib Nephrol 1996 0.78
183 Mechanism of the gene expression of HTLV-I and its association with ATL. AIDS Res 1986 0.78
184 A BALB/c 3T3-transformed cell line suitable for transfection assay of metastasis-inducing genes. Int J Cancer 1997 0.78
185 Hemostatic effects of microfibrillar collagen hemostat (MCH) in experimental coagulopathy model and its mechanism of hemostasis. Thromb Res 1986 0.78
186 Pulmonary metastatic lesion of endolymphatic stromal myosis expresses metastasis-related genes but not invasion-related matrix type metalloproteinase. Cancer Lett 1997 0.78
187 Elevated cyclic AMP suppresses ConA-induced MT1-MMP expression in MDA-MB-231 human breast cancer cells. Clin Exp Metastasis 1998 0.78
188 Assignment of the genes for membrane-type-4 matrix metalloproteinase (Mmp17, MMP17) to mouse chromosome 5, human chromosome band 12q24.3 and membrane-type-5 matrix metalloproteinase (Mmp24, MMP24) to mouse chromosome 2 and human chromosome band 20q11.2-->q12, respectively, by radiation hybrid and in situ hybridization. Cytogenet Cell Genet 1999 0.77
189 [Studies on the healing promoting action of Z-103 in chronic gastric ulcer models of rats]. Nihon Yakurigaku Zasshi 1992 0.77
190 Nakahara memorial lecture. Human T-cell leukemia virus type I: molecular biology and its implications in adult T-cell leukemia. Princess Takamatsu Symp 1984 0.77
191 Heat shock suppresses membrane type 1-matrix metalloproteinase production and progelatinase A activation in human fibrosarcoma HT-1080 cells and thereby inhibits cellular invasion. Biochem Biophys Res Commun 1999 0.77
192 Lymphoma type adult T-cell leukemia--a clinicopathologic study of HTLV related T-cell type malignant lymphoma. Hematol Oncol 1986 0.77
193 Characterization of simian retrovirus genome related to human T-cell leukemia virus type I. Princess Takamatsu Symp 1984 0.77
194 Cell type-specific involvement of furin in membrane type 1 matrix metalloproteinase-mediated progelatinase A activation. Ann N Y Acad Sci 1999 0.77
195 Expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) mRNA in trophoblast and endometrial epithelial cell populations of the synepitheliochorial placenta of goats (Capra hircus). Arch Histol Cytol 2001 0.77
196 Flow injection analysis for measurement of activity of matrix metalloproteinase-7 (MMP-7). J Pharm Biomed Anal 1997 0.77
197 Cell-cell contact down-regulates expression of membrane type metalloproteinase-1 (MT1-MMP) in a mouse mammary gland epithelial cell line. Zoolog Sci 1997 0.77
198 Identification of cis-acting promoter elements that support expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) in v-src transformed Madin-Darby canine kidney cells. Clin Exp Metastasis 2000 0.76
199 Induction of membrane-type matrix metalloproteinase-1 stimulates angiogenic activities of bovine aortic endothelial cells. Angiogenesis 1999 0.76
200 Plasma fibrinolysis after intraduodenal administration of urokinase in rats. Enzyme 1985 0.76
201 [Molecular biology of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs), and the regulation of these genes in tumor tissues]. Nihon Rinsho 1995 0.75
202 Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization. Genomics 1997 0.75
203 Development and application of a microplate assay method for the mass screening of MMP inhibitors. Ann N Y Acad Sci 1999 0.75
204 Effects of a new histamine H2-receptor antagonist, Z-300, on gastric secretion and gastro-duodenal lesions in rats: comparison with roxatidine. Jpn J Pharmacol 1992 0.75
205 Experimental metastasis of oncogene-transformed NIH 3T3 cells in chick embryo. Jpn J Cancer Res 1992 0.75
206 Antiulcer agents. II. Synthesis and gastric acid antisecretory activity of N-[3-(3-(piperidinomethyl)phenoxy)propyl]-4-(1-methyl-1H- tetrazol-5-ylthio)butanamide and related compounds. Chem Pharm Bull (Tokyo) 1991 0.75
207 [The role of matrix metalloproteinases in cancer invasion and metastasis]. Tanpakushitsu Kakusan Koso 1997 0.75
208 Epstein-Barr virus lytic cycle spreads via cell fusion in a nasopharyngeal carcinoma hybrid cell line. Laryngoscope 1994 0.75
209 Synthesis and pharmacological properties of N-[3-(3-(1-Piperidinylmethyl)phenoxy)propyl]-2-(2-hydroxyethylthio)- acetamide and related compounds as antiulcer agents. I. Chem Pharm Bull (Tokyo) 1990 0.75
210 The molecular biology of human T cell leukemia virus and its roles in leukemogenesis of adult T cell leukemia. Haematol Blood Transfus 1985 0.75
211 [Studies on antiulcer agents. I. The effects of various methanol and aqueous extracts of crude drugs on antiulcer activity]. Yakugaku Zasshi 1994 0.75
212 [Expression of membrane-type matrix metalloproteinase (MT-MMP) and activation of MMP-2 in lung cancer]. Nihon Rinsho 1995 0.75
213 [Studies on antiulcer agents. III. Synthesis and antiulcer activity of phenylpropanol derivatives]. Yakugaku Zasshi 1995 0.75
214 [Studies on antiulcer agents. II. Synthesis and antiulcer activity of phenylpropanol derivatives]. Yakugaku Zasshi 1994 0.75
215 Report of the Fifth International Conference on Human Retrovirology: Human T-cell Lymphotropic Virus. Jpn J Clin Oncol 1993 0.75
216 [Studies on antiulcer agents. IV. Synthesis and antiulcer activity of phenylpropanol derivatives]. Yakugaku Zasshi 1995 0.75
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