Published in Nucleic Acids Res on July 11, 1994
DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene. Proc Natl Acad Sci U S A (1995) 1.33
Fork-like DNA templates support bypass replication of lesions that block DNA synthesis on single-stranded templates. Proc Natl Acad Sci U S A (1996) 0.98
Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase. Nucleic Acids Res (2008) 0.97
Replication bypass and mutagenic effect of alpha-deoxyadenosine site-specifically incorporated into single-stranded vectors. Nucleic Acids Res (1997) 0.93
Solution structures of a DNA dodecamer duplex with and without a cisplatin 1,2-d(GG) intrastrand cross-link: comparison with the same DNA duplex containing an oxaliplatin 1,2-d(GG) intrastrand cross-link. Biochemistry (2007) 0.91
Mutagenic and genotoxic effects of DNA adducts formed by the anticancer drug cis-diamminedichloroplatinum(II). Nucleic Acids Res (1995) 0.88
A comprehensive survey of the mutagenic impact of common cancer cytotoxics. Genome Biol (2016) 0.88
Mammalian assay for site-specific DNA damage processing using the human H-ras proto-oncogene. Nucleic Acids Res (1995) 0.80
Studies on transformation of Escherichia coli with plasmids. J Mol Biol (1983) 116.81
ras genes. Annu Rev Biochem (1987) 22.59
ras oncogenes in human cancer: a review. Cancer Res (1989) 22.03
Enchancement of the infectivity of simian virus 40 deoxyribonucleic acid with diethylaminoethyl-dextran. J Natl Cancer Inst (1968) 21.44
Drugs five years later. Cisplatin. Ann Intern Med (1984) 3.69
The 'A rule' of mutagen specificity: a consequence of DNA polymerase bypass of non-instructional lesions? Bioessays (1991) 2.51
Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair. J Biol Chem (1994) 2.36
Base-pair substitution hotspots in GAG and GCG nucleotide sequences in Escherichia coli K-12 induced by cis-diamminedichloroplatinum (II). Proc Natl Acad Sci U S A (1981) 1.66
Site-specifically modified oligodeoxynucleotides as probes for the structural and biological effects of DNA-damaging agents. Chem Res Toxicol (1992) 1.53
Replication inhibition and translesion synthesis on templates containing site-specifically placed cis-diamminedichloroplatinum(II) DNA adducts. Biochemistry (1992) 1.33
An intrastrand d(GpG) platinum crosslink in duplex M13 DNA is refractory to repair by human cell extracts. Proc Natl Acad Sci U S A (1992) 1.29
Transcription by eucaryotic and procaryotic RNA polymerases of DNA modified at a d(GG) or a d(AG) site by the antitumor drug cis-diamminedichloroplatinum(II). Biochemistry (1991) 1.29
Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients. Proc Natl Acad Sci U S A (1993) 1.28
Spectrum of cisplatin-induced mutations in Escherichia coli. Proc Natl Acad Sci U S A (1987) 1.28
Chemical probes of the conformation of DNA modified by cis-diamminedichloroplatinum(II). Biochemistry (1989) 1.25
Effect of single DNA lesions on in vitro replication with DNA polymerase III holoenzyme. Comparison with other polymerases. J Mol Biol (1994) 1.20
Is cisplatin a human carcinogen? J Natl Cancer Inst (1992) 1.11
Mutagenic properties of a unique abasic site in mammalian cells. Biochem Biophys Res Commun (1990) 1.08
Sequence specificity of mutation induced by the anti-tumor drug cisplatin in the CHO aprt gene. Carcinogenesis (1989) 1.06
The use of Taq DNA polymerase to determine the sequence specificity of DNA damage caused by cis-diamminedichloroplatinum(II), acridine-tethered platinum(II) diammine complexes or two analogues. J Biol Chem (1992) 1.03
Increased resistance to cis-diamminedichloroplatinum(II) in NIH 3T3 cells transformed by ras oncogenes. Cancer Res (1988) 1.03
Inhibition of Rad3 DNA helicase activity by DNA adducts and abasic sites: implications for the role of a DNA helicase in damage-specific incision of DNA. Biochemistry (1993) 1.03
Sites of termination of in vitro DNA synthesis on cis-diamminedichloroplatinum(II) treated single-stranded DNA: a comparison between E. coli DNA polymerase I and eucaryotic DNA polymerases alpha. Nucleic Acids Res (1988) 1.02
cis-diamminedichloroplatinum(II) induced distortion of a single and double stranded deoxydecanucleosidenonaphosphate studied by nuclear magnetic resonance. J Biomol Struct Dyn (1985) 1.02
Single d(ApG)/cis-diamminedichloroplatinum(II) adduct-induced mutagenesis in Escherichia coli. Proc Natl Acad Sci U S A (1990) 0.95
Chemical and biological studies of the major DNA adduct of cis-diamminedichloroplatinum(II), cis-[Pt(NH3)2(d(GpG]], built into a specific site in a viral genome. Biochemistry (1988) 0.94
Mutagenicity and genotoxicity of the major DNA adduct of the antitumor drug cis-diamminedichloroplatinum(II). Biochemistry (1993) 0.94
Analysis of mutations induced in the SUP4-o gene of Saccharomyces cerevisiae by cis-diammine dichloroplatinum(II). Carcinogenesis (1990) 0.94
The development of transient SV40 based shuttle vectors for mutagenesis studies: problems and solutions. Mutat Res (1989) 0.93
Simian virus 40 (SV40) large T antigen-dependent amplification of an Epstein-Barr virus-SV40 hybrid shuttle vector integrated into the human HeLa cell genome. J Gen Virol (1992) 0.91
Spectrum of cis-diamminedichloroplatinum(II)-induced mutations in a shuttle vector propagated in human cells. Mol Carcinog (1991) 0.89
Expression of the c-Ha-ras oncogene in mouse NIH 3T3 cells induces resistance to cisplatin. Cancer Res (1991) 0.89
A d(GpG)-platinated decanucleotide duplex is kinked. An extended NMR and molecular mechanics study. Eur J Biochem (1990) 0.88
Transplacental carcinogenicity of cisplatin: initiation of skin tumors and induction of other preneoplastic and neoplastic lesions in SENCAR mice. Cancer Res (1993) 0.87
Effects of a single intrastrand d(GpG) platinum adduct on the strand separating activity of the Escherichia coli proteins RecB and RecA. FEBS Lett (1993) 0.85
Conversion of a single-stranded simian virus 40 (SV40)-based shuttle vector to its double-stranded form does not require the SV40 T antigen in monkey cells. J Gen Virol (1991) 0.84
Repair synthesis by human cell extracts in cisplatin-damaged DNA is preferentially determined by minor adducts. Nucleic Acids Res (1992) 0.84
Effects of the anticancer drug cis-diamminedichloroplatinum(II) on the activities of calf thymus DNA polymerase epsilon. Biochemistry (1993) 0.82
Characterization and localization of cis-diamminedichloro-platinum(II) adducts on a purified oligonucleotide containing the codons 12 and 13 of H-ras proto-oncogene. Nucleic Acids Res (1992) 0.82
In vitro mutational specificity of cisplatin in the human hypoxanthine guanine phosphoribosyltransferase gene. Cancer Res (1992) 0.81
Restriction-enzyme cleavage of DNA modified by platinum(II) complexes. Eur J Biochem (1993) 0.81
Codons 12 and 13 of H-ras protooncogene interrupt the progression of DNA synthesis catalyzed by DNA polymerase alpha. Cancer Res (1993) 0.80
Enhanced malignant conversion of benign mouse skin tumors by cisplatin. J Natl Cancer Inst (1990) 0.79
Activity of calf thymus DNA helicase E on cis-diamminedichloroplatinum (II)-damaged DNA. J Biol Chem (1993) 0.78
Ultraviolet reactivation and ultraviolet mutagenesis of lambda in different genetic systems. Virology (1971) 2.83
Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation. Nucleic Acids Res (1998) 2.63
The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor. EMBO J (1994) 2.60
Mechanism of ultraviolet-induced mutagenesis: extent and fidelity of in vitro DNA synthesis on irradiated templates. Proc Natl Acad Sci U S A (1978) 2.48
Retracted Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome. Cell (2000) 2.25
Replicational fidelity: mechanisms of mutation avoidance and mutation fixation. Cold Spring Harb Symp Quant Biol (1979) 2.10
High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation. Oncogene (1997) 1.91
Induction kinetics of mutagenic DNA repair activity in E. coli following ultraviolet irradiation. Mol Gen Genet (1976) 1.88
Xeroderma pigmentosum and trichothiodystrophy are associated with different mutations in the XPD (ERCC2) repair/transcription gene. Proc Natl Acad Sci U S A (1997) 1.87
High expression of DNA repair pathways is associated with metastasis in melanoma patients. Oncogene (2007) 1.83
Molecular mechanisms of induced mutagenesis. Replication in vivo of bacteriophage phiX174 single-stranded, ultraviolet light-irradiated DNA in intact and irradiated host cells. J Mol Biol (1977) 1.78
Mutation update for the CSB/ERCC6 and CSA/ERCC8 genes involved in Cockayne syndrome. Hum Mutat (2010) 1.67
Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1. Proc Natl Acad Sci U S A (2001) 1.61
A new nucleotide-excision-repair gene associated with the disorder trichothiodystrophy. Am J Hum Genet (1993) 1.51
Frequent alteration of DNA damage signalling and repair pathways in human colorectal cancers with microsatellite instability. Oncogene (2007) 1.50
Pathways of mutagenesis and repair in Escherichia coli exposed to low levels of simple alkylating agents. J Bacteriol (1978) 1.43
A mutation in the XPB/ERCC3 DNA repair transcription gene, associated with trichothiodystrophy. Am J Hum Genet (1997) 1.40
Trichothiodystrophy: update on the sulfur-deficient brittle hair syndromes. J Am Acad Dermatol (2001) 1.40
Induction of an error-prone mode of DNA repair in UV-irradiated monkey kidney cells. Mutat Res (1980) 1.39
Sequence effect on alkali-sensitive sites in UV-irradiated SV40 DNA. Nucleic Acids Res (1987) 1.38
BRCA1 and BRCA2 are necessary for the transcription-coupled repair of the oxidative 8-oxoguanine lesion in human cells. Cancer Res (2000) 1.36
DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene. Proc Natl Acad Sci U S A (1995) 1.33
Targeted mutagenesis of SV40 DNA induced by UV light. Nature (1983) 1.33
Two individuals with features of both xeroderma pigmentosum and trichothiodystrophy highlight the complexity of the clinical outcomes of mutations in the XPD gene. Hum Mol Genet (2001) 1.33
Genetic heterogeneity of the excision repair defect associated with trichothiodystrophy. Carcinogenesis (1993) 1.32
DNA polymerase alpha from Drosophila melanogaster embryos. Subunit structure. J Biol Chem (1980) 1.29
Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients. Proc Natl Acad Sci U S A (1993) 1.28
Mutagenicity of a unique apurinic/apyrimidinic site in mammalian cells. J Mol Biol (1992) 1.25
Role of the E. coli umuC gene product in the repair of single-stranded DNA phage. Mol Gen Genet (1983) 1.25
Elongation of RNA-primed DNA templates by DNA polymerase alpha from Drosophila melanogaster embryos. J Biol Chem (1981) 1.24
Galectin-7 overexpression is associated with the apoptotic process in UVB-induced sunburn keratinocytes. Proc Natl Acad Sci U S A (1999) 1.23
Transcription coupled repair of 8-oxoguanine in murine cells: the ogg1 protein is required for repair in nontranscribed sequences but not in transcribed sequences. Proc Natl Acad Sci U S A (2000) 1.22
SOS response in mammalian cells. Cancer Invest (1985) 1.22
p53 mutations in skin and internal tumors of xeroderma pigmentosum patients belonging to the complementation group C. Cancer Res (1998) 1.20
Signal of induction of recA protein in E. coli. Mutat Res (1984) 1.20
The adaptive response of E.coli to low levels of alkylating agent: the role of polA in killing adaptation. Mol Gen Genet (1978) 1.17
Two-stage malignant transformation of rat fibroblasts in tissue culture. Nature (1974) 1.16
Measles epidemic in the urban community of Niamey: transmission patterns, vaccine efficacy and immunization strategies, Niger, 1990 to 1991. Pediatr Infect Dis J (1994) 1.16
Developmental exposure of rats to a reconstituted PCB mixture or aroclor 1254: effects on organ weights, aromatase activity, sex hormone levels, and sweet preference behavior. Toxicol Appl Pharmacol (1999) 1.15
The role of umuC gene product in mutagenesis by simple alkylating agents. Mol Gen Genet (1980) 1.13
In vitro bypass replication of the cisplatin-d(GpG) lesion by calf thymus DNA polymerase beta and human immunodeficiency virus type I reverse transcriptase is highly mutagenic. J Biol Chem (1996) 1.13
The Bacillus subtilis genome from gerBC (311 degrees) to licR (334 degrees). Microbiology (1997) 1.12
Mutation spectrum of heat-induced abasic sites on a single-stranded shuttle vector replicated in mammalian cells. J Biol Chem (1992) 1.12
Transfection of mitochondria: strategy towards a gene therapy of mitochondrial DNA diseases. Nucleic Acids Res (1995) 1.11
The role of UV-B light in skin carcinogenesis through the analysis of p53 mutations in squamous cell carcinomas of hairless mice. Carcinogenesis (1997) 1.11
The Cohen syndrome: clinical and endocrinological studies of two new cases. J Med Genet (1980) 1.09
Defects in the DNA repair and transcription gene ERCC2(XPD) in trichothiodystrophy. Am J Hum Genet (1996) 1.09
Variability in nucleotide excision repair and cancer risk: a review. Mutat Res (2000) 1.09
Mutagenic properties of a unique abasic site in mammalian cells. Biochem Biophys Res Commun (1990) 1.08
An immortalized xeroderma pigmentosum, group C, cell line which replicates SV40 shuttle vectors. Mutat Res (1987) 1.08
The proapoptotic effect of hepatitis B virus HBx protein correlates with its transactivation activity in stably transfected cell lines. Oncogene (1999) 1.08
Coding properties of a unique apurinic/apyrimidinic site replicated in mammalian cells. J Mol Biol (1994) 1.07
Cell survival and shuttle vector mutagenesis induced by ultraviolet A and ultraviolet B radiation in a human cell line. J Invest Dermatol (1996) 1.07
The UL8 subunit of the herpes simplex virus type-1 DNA helicase-primase optimizes utilization of DNA templates covered by the homologous single-strand DNA-binding protein ICP8. J Biol Chem (1996) 1.06
Relationship between pyrimidine dimers, 6-4 photoproducts, repair synthesis and cell survival: studies using cells from patients with trichothiodystrophy. Mutat Res (1990) 1.05
Replication of simian virus 40 DNA after UV irradiation: evidence of growing fork blockage and single-stranded gaps in daughter strands. J Virol (1988) 1.04
Prolonged p53 protein accumulation in trichothiodystrophy fibroblasts dependent on unrepaired pyrimidine dimers on the transcribed strands of cellular genes. Mol Carcinog (1997) 1.04
Singlet oxygen induced DNA damage and mutagenicity in a single-stranded SV40-based shuttle vector. Photochem Photobiol (1992) 1.04
Prenatal diagnosis of recurrence of cystic hygroma with normal chromosomes. Prenat Diagn (1985) 1.03
Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins. Nucleic Acids Res (2002) 1.03
Can we predict solar ultraviolet radiation as the causal event in human tumours by analysing the mutation spectra of the p53 gene? Mutat Res (1994) 1.03
Development of a new easy complementation assay for DNA repair deficient human syndromes using cloned repair genes. Carcinogenesis (1995) 1.01
Mutagenicity of a unique 8-oxoguanine in a human Ha-ras sequence in mammalian cells. Carcinogenesis (1995) 1.00
Phase II study of continuous-infusion high-dose ifosfamide in advanced and/or metastatic pretreated soft tissue sarcomas. Ann Oncol (1997) 0.99
Repair and mutagenic potency of 8-oxoG:A and 8-oxoG:C base pairs in mammalian cells. Nucleic Acids Res (1998) 0.99
Molecular cloning and characterization of the human KIN17 cDNA encoding a component of the UVC response that is conserved among metazoans. Carcinogenesis (2000) 0.99
Mutagenicity of a unique thymine-thymine dimer or thymine-thymine pyrimidine pyrimidone (6-4) photoproduct in mammalian cells. Nucleic Acids Res (1996) 0.99
Cerebro-oculo-facio-skeletal syndrome: three additional cases with CSB mutations, new diagnostic criteria and an approach to investigation. J Med Genet (2008) 0.99
Equilibrium binding of single-stranded DNA with herpes simplex virus type I-coded single-stranded DNA-binding protein, ICP8. J Biol Chem (2000) 0.98
Fork-like DNA templates support bypass replication of lesions that block DNA synthesis on single-stranded templates. Proc Natl Acad Sci U S A (1996) 0.98
The specificity of p53 mutation spectra in sunlight induced human cancers. J Photochem Photobiol B (1995) 0.98
UV-specific mutations of the human patched gene in basal cell carcinomas from normal individuals and xeroderma pigmentosum patients. Mutat Res (2000) 0.97
Differential behaviors toward ultraviolet A and B radiation of fibroblasts and keratinocytes from normal and DNA-repair-deficient patients. Cancer Res (1999) 0.97
Association between INK4a-ARF and p53 mutations in skin carcinomas of xeroderma pigmentosum patients. J Natl Cancer Inst (2000) 0.96
Mutation spectrum following transfection of ultraviolet-irradiated single-stranded or double-stranded shuttle vector DNA into monkey cells. J Mol Biol (1991) 0.96
Wide clinical variability among 13 new Cockayne syndrome cases confirmed by biochemical assays. Arch Dis Child (2006) 0.95
Distribution of ultraviolet-induced lesions in simian virus 40 DNA. Biochimie (1985) 0.95
The nuclear concentration of kin17, a mouse protein that binds to curved DNA, increases during cell proliferation and after UV irradiation. Carcinogenesis (1998) 0.95
Molecular analysis of DNA junctions produced by illegitimate recombination in human cells. Nucleic Acids Res (1992) 0.95
Rate-limiting step preceding cytochrome c release in cells primed for Fas-mediated apoptosis revealed by analysis of cellular mosaicism of respiratory changes. J Biol Chem (2001) 0.95
Recovery of respiration following the SOS response of Escherichia coli requires RecA-mediated induction of 2-keto-4-hydroxyglutarate aldolase. Proc Natl Acad Sci U S A (1995) 0.95
Transmembrane diffusion of gemcitabine by a nanoparticulate squalenoyl prodrug: an original drug delivery pathway. J Control Release (2010) 0.95
Apurinic sites cause mutations in simian virus 40. Mutat Res (1984) 0.94
High mutation frequency in ras genes of skin tumors isolated from DNA repair deficient xeroderma pigmentosum patients. Cancer Res (1993) 0.94
Simian virus 40 as a probe for studying inducible repair functions in mammalian cells. J Supramol Struct Cell Biochem (1981) 0.93