C P Hollenberg

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 1999 3.86
2 Mitochondrial DNA. V. A 25 micron closed circular duplex DNA molecule in wild-type yeast mitochondria. Stucture and genetic complexity. Biochim Biophys Acta 1970 3.67
3 Complete DNA sequence of yeast chromosome XI. Nature 1994 3.51
4 An efficient transformation procedure enabling long-term storage of competent cells of various yeast genera. Yeast 1991 3.41
5 The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants. EMBO J 1994 3.10
6 The presence of a defective LEU2 gene on 2 mu DNA recombinant plasmids of Saccharomyces cerevisiae is responsible for curing and high copy number. J Bacteriol 1983 2.55
7 Characterization of 2-mum DNA of Saccharomyces cerevisiae by restriction fragment analysis and integration in an Escherichia coli plasmid. Proc Natl Acad Sci U S A 1976 2.47
8 The molecular genetics of hexose transport in yeasts. FEMS Microbiol Rev 1997 2.26
9 Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach. Mol Gen Genet 1999 2.26
10 Saccharomyces cerevisiae ribosomes recognize non-AUG initiation codons. Mol Cell Biol 1984 2.22
11 Molecular cloning and characterization of a gene coding for methanol oxidase in Hansenula polymorpha. Nucleic Acids Res 1985 2.19
12 Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. EMBO J 1996 2.06
13 Complete DNA sequence of yeast chromosome II. EMBO J 1994 1.97
14 Isolation and characterization of the Pichia stipitis xylitol dehydrogenase gene, XYL2, and construction of a xylose-utilizing Saccharomyces cerevisiae transformant. Curr Genet 1990 1.75
15 Activation of Gal4p by galactose-dependent interaction of galactokinase and Gal80p. Science 1996 1.74
16 Nucleotide sequence of the Bacillus subtilis xylose isomerase gene: extensive homology between the Bacillus and Escherichia coli enzyme. Nucleic Acids Res 1985 1.57
17 Cloning of the structural gene (ompA) for an integral outer membrane protein of Escherichia coli K-12. Proc Natl Acad Sci U S A 1979 1.46
18 Galactokinase encoded by GAL1 is a bifunctional protein required for induction of the GAL genes in Kluyveromyces lactis and is able to suppress the gal3 phenotype in Saccharomyces cerevisiae. Mol Cell Biol 1991 1.45
19 Characterization of a glucose-repressed pyruvate kinase (Pyk2p) in Saccharomyces cerevisiae that is catalytically insensitive to fructose-1,6-bisphosphate. J Bacteriol 1997 1.45
20 Cloning and characterization of the DAS gene encoding the major methanol assimilatory enzyme from the methylotrophic yeast Hansenula polymorpha. Nucleic Acids Res 1985 1.41
21 Biosynthesis and regulation of the peroxisomal methanol oxidase from the methylotrophic yeast Hansenula polymorpha. Mol Gen Genet 1984 1.41
22 Cloning and expression in Saccharomyces cerevisiae of the NAD(P)H-dependent xylose reductase-encoding gene (XYL1) from the xylose-assimilating yeast Pichia stipitis. Gene 1991 1.36
23 Saccharomyces cerevisiae Apl2p, a homologue of the mammalian clathrin AP beta subunit, plays a role in clathrin-dependent Golgi functions. J Cell Sci 1995 1.36
24 Expression and processing of bacterial beta-lactamase in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 1981 1.35
25 Selective cloning of Bacillus subtilis xylose isomerase and xylulokinase in Escherichia coli genes by IS5-mediated expression. EMBO J 1984 1.32
26 Analysis of the primary structure and promoter function of a pyruvate decarboxylase gene (PDC1) from Saccharomyces cerevisiae. Nucleic Acids Res 1986 1.31
27 STE50, a novel gene required for activation of conjugation at an early step in mating in Saccharomyces cerevisiae. Mol Gen Genet 1992 1.29
28 Positive regulation of the beta-galactosidase gene from Kluyveromyces lactis is mediated by an upstream activation site that shows homology to the GAL upstream activation site of Saccharomyces cerevisiae. Mol Cell Biol 1987 1.23
29 Transcription of the bacterial beta-lactamase gene in Saccharomyces cerevisiae. Gene 1982 1.20
30 Saccharomyces cerevisiae 2-mum DNA. An analysis of the monomer and its multimers by electron microscopy. Mol Gen Genet 1977 1.18
31 The HTR1 gene is a dominant negative mutant allele of MTH1 and blocks Snf3- and Rgt2-dependent glucose signaling in yeast. J Bacteriol 2000 1.17
32 Cloning and characterization of three genes (SUT1-3) encoding glucose transporters of the yeast Pichia stipitis. Mol Microbiol 1999 1.17
33 Precursor of beta-lactamase is enzymatically inactive. Accumulation of the preprotein in Saccharomyces cerevisiae. J Biol Chem 1985 1.15
34 Ste50p is involved in regulating filamentous growth in the yeast Saccharomyces cerevisiae and associates with Ste11p. Mol Gen Genet 1998 1.14
35 Analysis of a eukaryotic beta-galactosidase gene: the N-terminal end of the yeast Kluyveromyces lactis protein shows homology to the Escherichia coli lacZ gene product. Nucleic Acids Res 1984 1.12
36 Ste50p sustains mating pheromone-induced signal transduction in the yeast Saccharomyces cerevisiae. Mol Microbiol 1996 1.11
37 Application of yeasts in gene expression studies: a comparison of Saccharomyces cerevisiae, Hansenula polymorpha and Kluyveromyces lactis -- a review. Gene 1997 1.08
38 High-level expression of foreign genes in Hansenula polymorpha. Biotechnol Adv 1992 1.08
39 Mutations in the SAM domain of STE50 differentially influence the MAPK-mediated pathways for mating, filamentous growth and osmotolerance in Saccharomyces cerevisiae. Mol Genet Genomics 2001 1.07
40 Heterologous gene expression in Hansenula polymorpha: efficient secretion of glucoamylase. Biotechnology (N Y) 1991 1.07
41 Catabolite inactivation of the high-affinity hexose transporters Hxt6 and Hxt7 of Saccharomyces cerevisiae occurs in the vacuole after internalization by endocytosis. FEBS Lett 1998 1.05
42 ERA, a novel cis-acting element required for autoregulation and ethanol repression of PDC1 transcription in Saccharomyces cerevisiae. Mol Microbiol 1996 1.03
43 Xylose isomerase from Actinoplanes missouriensis: primary structure of the gene and the protein. Nucleic Acids Res 1989 1.03
44 Simultaneous expression of the S and L surface antigens of hepatitis B, and formation of mixed particles in the methylotrophic yeast, Hansenula polymorpha. Yeast 1991 1.02
45 Transformation of Kluyveromyces fragilis. J Bacteriol 1984 1.00
46 Transcription in yeast: a factor that stimulates yeast RNA polymerases. Proc Natl Acad Sci U S A 1972 1.00
47 Cloning with 2-micrometer DNA vectors and the expression of foreign genes in Saccharomyces cerevisiae. Curr Top Microbiol Immunol 1982 0.99
48 The glucose-and ethanol-dependent regulation of PDC1 from Saccharomyces cerevisiae are controlled by two distinct promoter regions. Curr Genet 1988 0.99
49 Inheritance of multiple drug resistance in Saccharomyces cerevisiae: linkage to leu1 and analyses of 2 micron DNA in partial revertants. Mol Gen Genet 1979 0.99
50 A positive regulatory element is involved in the induction of the beta-galactosidase gene from Kluyveromyces lactis. EMBO J 1985 0.97
51 The glutamate dehydrogenases of yeast: extra-mitochondrial enzymes. Biochim Biophys Acta 1970 0.96
52 pdc1(0) mutants of Saccharomyces cerevisiae give evidence for an additional structural PDC gene: cloning of PDC5, a gene homologous to PDC1. J Bacteriol 1990 0.96
53 The unusual properties of mtDNA from a "low-density" petite mutant of yeast. Biochim Biophys Acta 1972 0.95
54 A structural analysis of Balbiani ring dna sequences in Chironomus tentans. Chromosoma 1981 0.95
55 Cloning and sequencing of the ura3 locus of the methylotrophic yeast Hansenula polymorpha and its use for the generation of a deletion by gene replacement. Appl Microbiol Biotechnol 1993 0.94
56 Cloning of the Schwanniomyces occidentalis glucoamylase gene (GAM1) and its expression in Saccharomyces cerevisiae. Gene 1990 0.94
57 A putative P-type Cu(2+)-transporting ATPase gene on chromosome II of Saccharomyces cerevisiae. Yeast 1994 0.93
58 Mapping of regions on cloned Saccharomyces cerevisiae 2-mum DNA coding for polypeptides synthesized in Escherichia coli minicells. Mol Gen Genet 1978 0.93
59 Proportionate representation of rDNA and Balbiani ring DNA in polytene chromosomes of Chironomus tentans. Chromosoma 1976 0.92
60 Congenital sucrase-isomaltase deficiency. Identification of a glutamine to proline substitution that leads to a transport block of sucrase-isomaltase in a pre-Golgi compartment. J Clin Invest 1996 0.92
61 Transcriptional control of yeast phosphofructokinase gene expression. FEBS Lett 1991 0.92
62 Transaldolase mutants in the yeast Kluyveromyces lactis provide evidence that glucose can be metabolized through the pentose phosphate pathway. Mol Microbiol 1993 0.91
63 Galactose induction in yeast involves association of Gal80p with Gal1p or Gal3p. Mol Gen Genet 1999 0.91
64 LRG1 is expressed during sporulation in Saccharomyces cerevisiae and contains motifs similar to LIM and rho/racGAP domains. Nucleic Acids Res 1994 0.91
65 Heterologous protein production in yeast. Antonie Van Leeuwenhoek 1992 0.90
66 Isolation and characterization of the Pichia stipitis transketolase gene and expression in a xylose-utilising Saccharomyces cerevisiae transformant. Appl Microbiol Biotechnol 1994 0.90
67 Identification of sequences responsible for transcriptional regulation of the strongly expressed methanol oxidase-encoding gene in Hansenula polymorpha. Gene 1994 0.90
68 Non Xenopus-like DNA sequence organization in the Chironomus tentans genome. Mol Gen Genet 1976 0.89
69 Biosynthesis of the peroxisomal dihydroxyacetone synthase from Hansenula polymorpha in Saccharomyces cerevisiae induces growth but not proliferation of peroxisomes. Curr Genet 1989 0.89
70 Synthesis of high molecular weight polypeptides in Escherichia coli minicells directed by cloned Saccharomyces cerevisiae 2-micron DNA. Gene 1976 0.88
71 Size, structure and genetic complexity of yeast mitochondrial DNA. Biochim Biophys Acta 1969 0.88
72 The complete sequence of a 11,953 bp fragment from C1G on chromosome III encompasses four new open reading frames. Yeast 1991 0.88
73 Functional relationship among TATA sequences, gene induction and transcription initiation in the beta-galactosidase, LAC4, gene from Kluyveromyces lactis. Curr Genet 1989 0.87
74 Amino acid substitutions in the yeast Pichia stipitis xylitol dehydrogenase coenzyme-binding domain affect the coenzyme specificity. Eur J Biochem 1995 0.86
75 Pyrimidine tract analysis of mtDNA from a "low-density" petite mutant of yeast. Biochim Biophys Acta 1972 0.86
76 Regulation of cytochrome c expression in the aerobic respiratory yeast Kluyveromyces lactis. FEBS Lett 1995 0.85
77 Conditions that prevent rho - -induction by ethidium bromide. Biochem Biophys Res Commun 1971 0.85
78 Overproduction of BiP negatively affects the secretion of Aspergillus niger glucose oxidase by the yeast Hansenula polymorpha. Appl Microbiol Biotechnol 2002 0.85
79 Mediation, by Saccharomyces cerevisiae translocation signals, of beta-lactamase transport through the Escherichia coli inner membrane and sensitive method for detection of signal sequences. J Bacteriol 1986 0.84
80 Progress in developing methylotrophic yeasts as expression systems. Trends Biotechnol 1992 0.84
81 Molecular genetics of phosphofructokinase in the yeast Kluyveromyces lactis. Mol Microbiol 1993 0.84
82 Two novel gene expression systems based on the yeasts Schwanniomyces occidentalis and Pichia stipitis. Appl Microbiol Biotechnol 1998 0.84
83 Transcriptional control of yeast phosphoglycerate mutase-encoding gene. Gene 1993 0.83
84 A novel feature of DNA recognition: a mutant Gcn4p bZip peptide with dual DNA binding specificities dependent of half-site spacing. J Mol Biol 1999 0.83
85 Single-step co-integration of multiple expressible heterologous genes into the ribosomal DNA of the methylotrophic yeast Hansenula polymorpha. Appl Microbiol Biotechnol 2002 0.83
86 Conserved regulation of the Hansenula polymorpha MOX promoter in Saccharomyces cerevisiae reveals insights in the transcriptional activation by Adr1p. Eur J Biochem 1996 0.82
87 Sites for interaction between Gal80p and Gal1p in Kluyveromyces lactis: structural model of galactokinase based on homology to the GHMP protein family. J Mol Biol 2003 0.82
88 A high-frequency transformation system for the yeast Kluyveromyces lactis. Curr Genet 1982 0.82
89 Specific processing of the bacterial beta-lactamase precursor in Saccharomyces cerevisiae. J Cell Biochem 1983 0.81
90 Gene expression in methylotrophic yeasts. Bioprocess Technol 1995 0.81
91 Constitutive expression in gal7 mutants of Kluyveromyces lactis is due to internal production of galactose as an inducer of the Gal/Lac regulon. Mol Cell Biol 1997 0.81
92 The organization of the ribosomal RNA genes of Chironomus tentans and some closely related species. Chromosoma 1979 0.81
93 Cloning and characterization of the ribosomal RNA genes of Rhynchosciara americana. Chromosoma 1982 0.80
94 Bacterial beta-lactamase is efficiently secreted in Saccharomyces cerevisiae under control of the invertase signal sequence. Curr Genet 1992 0.80
95 The activation specificities of wild-type and mutant Gcn4p in vivo can be different from the DNA binding specificities of the corresponding bZip peptides in vitro. J Mol Biol 1998 0.80
96 Mutant invertase proteins accumulate in the yeast endoplasmic reticulum. Mol Gen Genet 1989 0.80
97 Cloning and characterization of the gene encoding a repressible acid phosphatase (PHO1) from the methylotrophic yeast Hansenula polymorpha. Appl Microbiol Biotechnol 1998 0.79
98 Striking structural and functional similarities suggest that intestinal sucrase-isomaltase, human lysosomal alpha-glucosidase and Schwanniomyces occidentalis glucoamylase are derived from a common ancestral gene. FEBS Lett 1991 0.79
99 Regulated overproduction of alpha-amylase by transformation of the amylolytic yeast Schwanniomyces occidentalis. Curr Genet 1989 0.79
100 Stable multicopy integration of vector sequences in Hansenula polymorpha. Appl Microbiol Biotechnol 1995 0.79
101 Curing of Saccharomyces cerevisiae 2-μm DNA by transformation. Curr Genet 1981 0.78
102 Analysis of the alpha-amylase gene of Schwanniomyces occidentalis and the secretion of its gene product in transformants of different yeast genera. Eur J Biochem 1989 0.78
103 Analysis of the DNA sequence of a 34,038 bp region on the left arm of yeast chromosome XV. Yeast 1997 0.78
104 Characterization of the active site of Schwanniomyces occidentalis glucoamylase by in vitro mutagenesis. Eur J Biochem 1997 0.76
105 Characterization of SFP2, a putative sulfate permease gene of Saccharomyces cerevisiae. Biochem Biophys Res Commun 1995 0.76
106 Characterization of the cytochrome c gene from the starch-fermenting yeast Schwanniomyces occidentalis and its expression in Baker's yeast. Yeast 1990 0.76
107 Mitochondrial DNA from cytoplasmic petite mutants of yeast. Biochim Biophys Acta 1972 0.76
108 Mapping of Escherichia coli RNA polymerase binding sites on 2-micrometers DNA from Saccharomyces cerevisiae. Heterogeneity within the inverted duplication and evidence for an eukaryotic invertible DNA sequence. Plasmid 1979 0.75
109 Ribosomal ribonucleic acid synthesis by isolated yeast ribonucleic acid polymerases. Biochemistry 1973 0.75
110 An analysis of a possible base sequence complementarity of mitochondrial and nuclear DNA in yeast. Biochim Biophys Acta 1970 0.75
111 Endoglucanase A gene fusion vectors for monitoring protein secretion and glycosylation in yeast. Anal Biochem 1991 0.75
112 Hybridization of poly(A)+RNA from salivary glands of Rhynchosciara americana to restriction DNA fragments and polytene chromosomes. Braz J Med Biol Res 1984 0.75
113 Expression of mouse anticreatine kinase (MAK33) monoclonal antibody in the yeast Hansenula polymorpha. Appl Microbiol Biotechnol 2001 0.75
114 Synthesis and farnesylation of a-factor fusion proteins in Saccharomyces cerevisiae. FEBS Lett 1993 0.75
115 The gene for the small ribosomal RNA on yeast mitochondrial DNA: Physical map, direction of transcription and absence of an intervening sequence. Curr Genet 1979 0.75
116 Recombinational properties of the Saccharomyces cerevisiae FLP gene expressed in Escherichia coli. Curr Genet 1984 0.75
117 Non-selective transformation of Saccharomyces cerevisiae. Curr Genet 1982 0.75
118 A region of the cellobiohydrolase I promoter from the filamentous fungus Trichoderma reesei mediates glucose repression in Saccharomyces cerevisiae, dependent on mitochondrial activity. Biochem Biophys Res Commun 1998 0.75
119 Study of salivary gland specific transcripts in Chironomus tentans by cDNA analysis. Chromosoma 1981 0.75
120 Synthesis of Escherichia coli outer membrane ompA protein in yeasts. Gene 1982 0.75
121 The hemolysin B protein, expressed in Saccharomyces cerevisiae, accumulates in binding-protein (BiP)-containing structures. Eur J Biochem 1996 0.75
122 The first hydrophobic segment of the ABC-transporter, Ste6, functions as a signal sequence. FEBS Lett 1994 0.75
123 Secretion and glycosylation of Clostridium thermocellum endoglucanase A encoded by the celA gene in Saccharomyces cerevisiae. Yeast 1989 0.75
124 Sequence of a cytochrome c gene from Kluyveromyces lactis and its upstream region. Yeast 1993 0.75