Published in Gene on August 19, 1994
Characterization and pathogenic significance of Vibrio vulnificus antigens preferentially expressed in septicemic patients. Infect Immun (2003) 2.69
Eukaryote-like serine/threonine kinases and phosphatases in bacteria. Microbiol Mol Biol Rev (2011) 1.82
Fancy meeting you here! A fresh look at "prokaryotic" protein phosphorylation. J Bacteriol (1996) 1.53
Expression and characterization of the Mycobacterium tuberculosis serine/threonine protein kinase PknB. Infect Immun (1999) 1.32
Regulation of daunorubicin production in Streptomyces peucetius by the dnrR2 locus. J Bacteriol (1995) 1.29
Role of Mycobacterium tuberculosis Ser/Thr kinase PknF: implications in glucose transport and cell division. J Bacteriol (2005) 1.21
Diversity in domain architectures of Ser/Thr kinases and their homologues in prokaryotes. BMC Genomics (2005) 1.20
A Streptomyces coelicolor antibiotic regulatory gene, absB, encodes an RNase III homolog. J Bacteriol (1999) 1.20
The Ser/Thr protein kinase AfsK regulates polar growth and hyphal branching in the filamentous bacteria Streptomyces. Proc Natl Acad Sci U S A (2012) 1.14
Tyrosine phosphorylation and bacterial virulence. Int J Oral Sci (2012) 1.11
The DnrN protein of Streptomyces peucetius, a pseudo-response regulator, is a DNA-binding protein involved in the regulation of daunorubicin biosynthesis. J Bacteriol (1996) 1.10
Isolation and cloning of a protein-serine/threonine phosphatase from an archaeon. J Bacteriol (1995) 1.05
Global negative regulation of Streptomyces coelicolor antibiotic synthesis mediated by an absA-encoded putative signal transduction system. J Bacteriol (1996) 1.05
Characterization of a Hank's type serine/threonine kinase and serine/threonine phosphoprotein phosphatase in Pseudomonas aeruginosa. J Bacteriol (1999) 1.03
The Pho regulon: a huge regulatory network in bacteria. Front Microbiol (2015) 1.03
Cloning, purification, and properties of a phosphotyrosine protein phosphatase from Streptomyces coelicolor A3(2). J Bacteriol (1996) 1.02
Functional characterization of a serine/threonine protein kinase of Pseudomonas aeruginosa. Infect Immun (1999) 0.98
Modulation of actinorhodin biosynthesis in Streptomyces lividans by glucose repression of afsR2 gene transcription. J Bacteriol (2001) 0.98
A deduced Thermomonospora curvata protein containing serine/threonine protein kinase and WD-repeat domains. J Bacteriol (1996) 0.98
AfsR as an integrator of signals that are sensed by multiple serine/threonine kinases in Streptomyces coelicolor A3(2). J Ind Microbiol Biotechnol (2003) 0.96
Identification of a gene negatively affecting antibiotic production and morphological differentiation in Streptomyces coelicolor A3(2). J Bacteriol (2006) 0.94
Identification of two eukaryote-like serine/threonine kinases encoded by Chlamydia trachomatis serovar L2 and characterization of interacting partners of Pkn1. Infect Immun (2003) 0.93
Involvement of AlpV, a new member of the Streptomyces antibiotic regulatory protein family, in regulation of the duplicated type II polyketide synthase alp gene cluster in Streptomyces ambofaciens. J Bacteriol (2005) 0.93
Pkg2, a novel transmembrane protein Ser/Thr kinase of Streptomyces granaticolor. J Bacteriol (1999) 0.93
Autophosphorylation of a bacterial serine/threonine kinase, AfsK, is inhibited by KbpA, an AfsK-binding protein. J Bacteriol (2001) 0.89
Regulation of prokaryotic gene expression by eukaryotic-like enzymes. Curr Opin Microbiol (2012) 0.87
Cloning and characterization of a gene involved in aerial mycelium formation in Streptomyces griseus. J Bacteriol (1995) 0.87
Complex transcriptional control of the antibiotic regulator afsS in Streptomyces: PhoP and AfsR are overlapping, competitive activators. J Bacteriol (2011) 0.84
A framework for classification of prokaryotic protein kinases. PLoS One (2010) 0.81
Cloning and analysis of a DNA fragment stimulating avermectin production in various Streptomyces avermitilis strains. Appl Environ Microbiol (2003) 0.80
Aspects of eukaryotic-like signaling in Gram-positive cocci: a focus on virulence. Future Microbiol (2011) 0.79
Effects of overexpression of Pkn2, a transmembrane protein serine/threonine kinase, on development of Myxococcus xanthus. J Bacteriol (1996) 0.79
Catalytic domain of AfsKav modulates both secondary metabolism and morphologic differentiation in Streptomyces avermitilis ATCC 31272. Curr Microbiol (2006) 0.78
Tyrosine Phosphorylation and Dephosphorylation in Burkholderia cenocepacia Affect Biofilm Formation, Growth under Nutritional Deprivation, and Pathogenicity. Appl Environ Microbiol (2015) 0.75
Regulatory genes and their roles for improvement of antibiotic biosynthesis in Streptomyces. 3 Biotech (2017) 0.75
Nucleotide sequence and functional map of pC194, a plasmid that specifies inducible chloramphenicol resistance. J Bacteriol (1982) 13.49
Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A. J Biol Chem (1990) 9.21
Nucleotide sequence and functional map of pE194, a plasmid that specifies inducible resistance to macrolide, lincosamide, and streptogramin type B antibodies. J Bacteriol (1982) 9.02
Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region. Proc Natl Acad Sci U S A (1999) 6.81
Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1. Exp Cell Res (1998) 6.11
Posttranscriptional modification of mRNA conformation: mechanism that regulates erythromycin-induced resistance. Proc Natl Acad Sci U S A (1980) 4.81
Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function. Bioessays (1995) 4.43
Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression. J Biol Chem (1994) 4.28
A complex attenuator regulates inducible resistance to macrolides, lincosamides, and streptogramin type B antibiotics in Streptococcus sanguis. J Bacteriol (1983) 3.91
Analysis of upstream elements in the HuC promoter leads to the establishment of transgenic zebrafish with fluorescent neurons. Dev Biol (2000) 2.93
Specific excretion of Serratia marcescens protease through the outer membrane of Escherichia coli. J Bacteriol (1986) 2.45
Trapoxin, an antitumor cyclic tetrapeptide, is an irreversible inhibitor of mammalian histone deacetylase. J Biol Chem (1993) 2.40
Autoregulatory factors and communication in actinomycetes. Annu Rev Microbiol (1992) 2.24
Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin. Proc Natl Acad Sci U S A (2001) 2.23
Unstable genetic determinant of A-factor biosynthesis in streptomycin-producing organisms: cloning and characterization. J Bacteriol (1984) 2.12
Mutants blocked in streptomycin production in Streptomyces griseus - the role of A-factor. J Antibiot (Tokyo) (1982) 2.08
Nucleotide sequence of the streptothricin acetyltransferase gene from Streptomyces lavendulae and its expression in heterologous hosts. J Bacteriol (1987) 2.08
A new pathway for polyketide synthesis in microorganisms. Nature (1999) 2.07
The A-factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus : identification of a target gene of the A-factor receptor. Mol Microbiol (1999) 2.00
The control region for erythromycin resistance: free energy changes related to induction and mutation to constitutive expression. Mol Gen Genet (1981) 2.00
Molecular cloning and cell cycle-dependent expression of mammalian CRM1, a protein involved in nuclear export of proteins. J Biol Chem (1997) 1.96
Cloning of a pleiotropic gene that positively controls biosynthesis of A-factor, actinorhodin, and prodigiosin in Streptomyces coelicolor A3(2) and Streptomyces lividans. J Bacteriol (1983) 1.94
Genetic analysis of A-factor synthesis in Streptomyces coelicolor A3(2) and Streptomyces griseus. J Gen Microbiol (1983) 1.91
Field test of quantum key distribution in the Tokyo QKD Network. Opt Express (2011) 1.89
FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor. Exp Cell Res (1998) 1.78
Pharmacokinetic study of S-1, a novel oral fluorouracil antitumor drug. Clin Cancer Res (1999) 1.76
A-factor as a microbial hormone that controls cellular differentiation and secondary metabolism in Streptomyces griseus. Mol Microbiol (1994) 1.68
Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3. Mol Pharmacol (2001) 1.67
Mechanics of respiration during submersion in water. J Appl Physiol (1969) 1.60
Development of a host-vector system in a Rhodococcus strain and its use for expression of the cloned nitrile hydratase gene cluster. J Gen Microbiol (1992) 1.60
A novel nuclear export signal sensitive to oxidative stress in the fission yeast transcription factor Pap1. J Biol Chem (1999) 1.58
Primary structure of AfsR, a global regulatory protein for secondary metabolite formation in Streptomyces coelicolor A3(2). Gene (1990) 1.57
Cloning of the Membrane-Bound Aldehyde Dehydrogenase Gene of Acetobacter polyoxogenes and Improvement of Acetic Acid Production by Use of the Cloned Gene. Appl Environ Microbiol (1989) 1.52
Cloning and sequencing of the gene cluster encoding two subunits of membrane-bound alcohol dehydrogenase from Acetobacter polyoxogenes. Biochim Biophys Acta (1991) 1.51
Detection and properties of A-factor-binding protein from Streptomyces griseus. J Bacteriol (1989) 1.50
Nucleotide sequence and transcriptional analysis of the Streptomyces griseus gene (afsA) responsible for A-factor biosynthesis. J Bacteriol (1989) 1.50
Amidase coupled with low-molecular-mass nitrile hydratase from Rhodococcus rhodochrous J1. Sequencing and expression of the gene and purification and characterization of the gene product. Eur J Biochem (1993) 1.50
Induction of streptomycin-inactivating enzyme by A-factor in Streptomyces griseus. J Antibiot (Tokyo) (1982) 1.44
Postoperative changes in cerebral metabolites associated with cognitive improvement and impairment after carotid endarterectomy: a 3T proton MR spectroscopy study. AJNR Am J Neuroradiol (2012) 1.44
Nucleotide sequence of the malate dehydrogenase gene of Thermus flavus and its mutation directing an increase in enzyme activity. J Biol Chem (1986) 1.42
Construction and application of a promoter-probe plasmid that allows chromogenic identification in Streptomyces lividans. J Bacteriol (1985) 1.42
Double-exponential curve fitting of isometric relaxation: a new measure for myocardial lusitropism. Am J Physiol (1995) 1.42
Cloning and nucleotide sequence of a cellulase gene, casA, from an alkalophilic Streptomyces strain. Gene (1988) 1.41
Cloning and characterization of the A-factor receptor gene from Streptomyces griseus. J Bacteriol (1995) 1.41
Reversible arrest of proliferation of rat 3Y1 fibroblasts in both the G1 and G2 phases by trichostatin A. Exp Cell Res (1988) 1.40
Cloning and sequencing of the major intracellular serine protease gene of Bacillus subtilis. J Bacteriol (1986) 1.39
Cloning and characterization of genes responsible for metabolism of nitrile compounds from Pseudomonas chlororaphis B23. J Bacteriol (1991) 1.38
Leptomycins A and B, new antifungal antibiotics. I. Taxonomy of the producing strain and their fermentation, purification and characterization. J Antibiot (Tokyo) (1983) 1.37
Gastroesophageal dynamics during immersion in water to the neck. J Appl Physiol (1975) 1.36
Protein serine/threonine kinases in signal transduction for secondary metabolism and morphogenesis in Streptomyces. Appl Microbiol Biotechnol (2002) 1.33
A rice homeobox gene, OSH1, is expressed before organ differentiation in a specific region during early embryogenesis. Proc Natl Acad Sci U S A (1996) 1.33
An A-factor-dependent extracytoplasmic function sigma factor (sigma(AdsA)) that is essential for morphological development in Streptomyces griseus. J Bacteriol (2000) 1.32
Restriction and modification in Bacillus species: genetic transformation of bacteria with DNA from different species, part I. Mol Gen Genet (1977) 1.31
Trichostatin and leptomycin. Inhibition of histone deacetylation and signal-dependent nuclear export. Ann N Y Acad Sci (1999) 1.30
Novel insertion sequence IS1380 from Acetobacter pasteurianus is involved in loss of ethanol-oxidizing ability. J Bacteriol (1991) 1.30
Induction of haem oxygenase-1 nitric oxide and ischaemia in experimental solid tumours and implications for tumour growth. Br J Cancer (1999) 1.29
Nucleotide sequence of afsB, a pleiotropic gene involved in secondary metabolism in Streptomyces coelicolor A3(2) and "Streptomyces lividans". J Bacteriol (1986) 1.28
Effects of leptomycin B on the cell cycle of fibroblasts and fission yeast cells. Exp Cell Res (1990) 1.27
Characterization of the precursor of Serratia marcescens serine protease and COOH-terminal processing of the precursor during its excretion through the outer membrane of Escherichia coli. J Bacteriol (1989) 1.27
Primary structure of nitrile hydratase deduced from the nucleotide sequence of a Rhodococcus species and its expression in Escherichia coli. Eur J Biochem (1989) 1.26
Antiapoptotic effect of haem oxygenase-1 induced by nitric oxide in experimental solid tumour. Br J Cancer (2003) 1.26
A blue protein as an inactivating factor for nitrite reductase from Alcaligenes faecalis strain S-6. J Biochem (1981) 1.25
Trichostatin A induces morphological changes and gelsolin expression by inhibiting histone deacetylase in human carcinoma cell lines. Exp Cell Res (1994) 1.25
Ixodid tick species recovered from domestic dogs in Japan. Med Vet Entomol (2003) 1.24
Histone deacetylase as a new target for cancer chemotherapy. Cancer Chemother Pharmacol (2001) 1.24
Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus. Biochemistry (1993) 1.24
Effects of trichostatins on differentiation of murine erythroleukemia cells. Cancer Res (1987) 1.24
Relationship between plasma cytokine concentration and multiple organ failure in patients with acute pancreatitis. Pancreas (2000) 1.23
A gene cluster involved in aerial mycelium formation in Streptomyces griseus encodes proteins similar to the response regulators of two-component regulatory systems and membrane translocators. J Bacteriol (1993) 1.22
Purification and properties of a copper-containing nitrite reductase from a denitrifying bacterium, Alcaligenes faecalis strain S-6. J Biochem (1981) 1.22
Oxamflatin is a novel antitumor compound that inhibits mammalian histone deacetylase. Oncogene (1999) 1.22
DNA-binding activity of the A-factor receptor protein and its recognition DNA sequences. Mol Microbiol (1997) 1.20
Risk factors for complications after partial splenic embolization for liver cirrhosis. Br J Surg (2008) 1.20
Involvement of the COOH-terminal pro-sequence of Serratia marcescens serine protease in the folding of the mature enzyme. J Biol Chem (1994) 1.18
A putative two-component regulatory system involved in secondary metabolism in Streptomyces spp. J Bacteriol (1992) 1.18