Published in J Immunol on July 01, 1975
Isolation of a lipid A bound polypeptide responsible for "LPS-initiated" mitogenesis of C3H/HeJ spleen cells. J Exp Med (1976) 2.88
Failure of endotoxin to increase nonspecific resistance to infection of lipopolysaccharide low-responder mice. Infect Immun (1976) 1.71
Adjuvant activity of mycobacterial fractions: adjuvant activity of synthetic N-acetylmuramyl-dipeptide and the related compounds. Infect Immun (1976) 1.70
Mitogenic effects of purified outer membrane proteins from Pseudomonas aeruginosa. Infect Immun (1980) 1.48
Mitogenic activity of staphylococcal peptidoglycan. Infect Immun (1979) 1.38
Mitogenic effects of bacterial cell walls, their fragments, and related synthetic compounds on thymocytes and splenocytes of guinea pigs. Infect Immun (1979) 1.36
Antibody response to streptococcal cell wall antigens associated with experimental arthritis in rats. Clin Exp Immunol (1980) 1.22
Effective immunity to dental caries: enhancement of salivary anti-Streptococcus mutans antibody responses with oral adjuvants. Infect Immun (1983) 1.20
Presence and subcellular localization of two distinct mitogenic fractions in the cells of Nocardia rubra and Nocardia opaca: preparation of soluble mitogenic peptidoglycan fractions. Infect Immun (1976) 1.18
Mitogenic analysis of murine B-cell heterogeneity. J Exp Med (1978) 1.13
N-acetyl muramyl dipeptide stimulation of bone resorption in tissue culture. Infect Immun (1982) 1.07
Edema-producing activity of group A streptococcal polysaccharide and its possible role in the pathogenesis of cell wall-induced polyarthritis. J Exp Med (1983) 1.07
Relationships between adjuvant, immunosuppressive, and mitogenic activities of staphylococcal peptidoglycan. Infect Immun (1979) 1.01
Induction of interleukin 1 secretion by adjuvant-active peptidoglycans. Infect Immun (1983) 0.99
The glycoprotein isolated from vesicular stomatitis virus is mitogenic for mouse B lymphocytes. J Exp Med (1981) 0.97
Immunological defect and its correction in the osteopetrotic mutant rat. Proc Natl Acad Sci U S A (1977) 0.97
Heat-labile B-cell mitogen obtained from Listeria monocytogenes. Infect Immun (1978) 0.96
Staphylococcal peptidoglycan: T-cell-dependent mitogen and relatively T-cell-independent polyclonal B-cell activator of human lymphocytes. Infect Immun (1983) 0.95
Cell walls, peptidoglycans, and teichoic acids of gram-positive bacteria as polyclonal inducers and immunomodulators of proliferative and lymphokine responses of human B and T lymphocytes. Infect Immun (1981) 0.95
Polyclonal response of human lymphocytes to bacterial cell walls, peptidoglycans and teichoic acids. Immunology (1982) 0.90
Studies on the mechanism of peptidoglycan- and lipopolysaccharide-induced polyclonal activation. Infect Immun (1982) 0.89
Production of interleukin-12 by murine macrophages in response to bacterial peptidoglycan. Infect Immun (1998) 0.87
Polyclonal activation of murine B cells by a membrane proteoglycan of Klebsiella pneumoniae. Clin Exp Immunol (1987) 0.87
Stimulation of lymphocyte proliferation by killed mycobacteria and other bacterial species. Infect Immun (1976) 0.87
Cell walls, peptidoglycans, and teichoic acids of Gram-positive bacteria as polyclonal inducers and immunomodulators of proliferative and lymphokine responses of human B and T lymphocytes. Infect Immun (1982) 0.84
Mitogenic activity of two Brucella fractions for murine B lymphocytes. Immunology (1980) 0.83
Evidence of mitogenic activity in periodontitis-associated bacteria. Infect Immun (1983) 0.78
Immunological activities of purified preparations of enterobacterial common antigen. Infect Immun (1982) 0.75
Effect of mucilage from yam on activation of lymphocytic immune cells. Nutr Res Pract (2007) 0.75
Oligomeric structure of gp41, the transmembrane protein of human immunodeficiency virus type 1. J Virol (1989) 4.07
Isolation and characterization of cDNAs encoding the heavy chain of human inter-alpha-trypsin inhibitor (I alpha TI): unambiguous evidence for multipolypeptide chain structure of I alpha TI. Proc Natl Acad Sci U S A (1987) 4.03
Defining criteria for autoimmune diseases (Witebsky's postulates revisited) Immunol Today (1993) 3.81
Enhancement of nonspecific immunity to Klebsiella pneumoniae infection by a synthetic immunoadjuvant (N-acetylmuramyl-L-alanyl-D-isoglutamine) and several analogs. Proc Natl Acad Sci U S A (1977) 3.31
Biological activities of muramyl dipeptide, a synthetic glycopeptide analogous to bacterial immunoregulating agents. Prog Allergy (1978) 3.08
Modulation of the immune response by a synthetic adjuvant and analogs. Proc Natl Acad Sci U S A (1976) 2.82
A proposed mechanism for natural immunity to enterobacterial pathogens. J Immunol (1968) 2.66
Toxic shock syndrome toxin 1 as an inducer of human tumor necrosis factors and gamma interferon. J Exp Med (1988) 2.61
Cellular basis of regulation of expression of idiotype. I. T-suppressor cells specific for MOPC 460 idiotype regulate the expression of cells secreting anti-TNP antibodies bearing 460 idiotype. J Exp Med (1979) 2.53
Macrophage activation by mycobacterial water soluble compounds and synthetic muramyl dipeptide. J Immunol (1979) 2.39
Primary Thrombosis of Cerebral Veins (following Childbirth). Br Med J (1941) 2.30
Further progress towards a catalogue of all Arabidopsis genes: analysis of a set of 5000 non-redundant ESTs. Plant J (1996) 2.27
Human plasma inter-alpha-trypsin inhibitor is encoded by four genes on three chromosomes. Eur J Biochem (1989) 2.12
Antiviral response elicited by a completely synthetic antigen with built-in adjuvanticity. Proc Natl Acad Sci U S A (1980) 2.07
Data quality assurance, monitoring, and reporting. Control Clin Trials (1995) 2.01
The wall peptidoglycans of Neisseria perflava, Moraxella glucidolytica, Pseudomonas alcaligenes and Proteus vulgaris strain P18. Eur J Biochem (1973) 1.99
Presentation of a viral T cell epitope expressed in the CDR3 region of a self immunoglobulin molecule. Science (1993) 1.96
Comparison between macrophage activation and enhancement of nonspecific resistance to tumors by mycobacterial immunoadjuvants. Proc Natl Acad Sci U S A (1975) 1.91
Influenza A virus transfectants with chimeric hemagglutinins containing epitopes from different subtypes. J Virol (1992) 1.88
Active antitoxic immunization by a diphtheria toxin synthetic oligopeptide. Nature (1981) 1.85
Carrier-induced epitopic suppression, a major issue for future synthetic vaccines. J Immunol (1985) 1.82
Complete sequence of one of the mRNAs coding for the small subunit of ribulose bisphosphate carboxylase of Nicotiana sylvestris. Biochimie (1985) 1.77
Granulomatous ulcerative colitis: a re-appraisal of the mucosal granuloma in the distinction of Crohn's disease from ulcerative colitis. Histopathology (2002) 1.76
Components of mycobacteria and muramyl dipeptide with adjuvant activity induce lymphocyte activating factor. Cell Immunol (1980) 1.76
Cellular basis of regulation of expression of idiotype. II. Immunity to anti-MOPC-460 idiotype antibodies increases the level of anti-trinitrophenyl antibodies bearing 460 idiotypes. J Exp Med (1979) 1.76
Expression of the gene coding for the small subunit of ribulosebisphosphate carboxylase during differentiation of tobacco plant protoplasts. Eur J Biochem (1982) 1.76
Microbial transformations of styrene and [14C] styrene in soil and enrichment cultures. Appl Environ Microbiol (1978) 1.74
Failure of endotoxin to increase nonspecific resistance to infection of lipopolysaccharide low-responder mice. Infect Immun (1976) 1.71
Sleep-promoting effects of endogenous pyrogen (interleukin-1). Am J Physiol (1984) 1.70
Chimeric influenza virus induces neutralizing antibodies and cytotoxic T cells against human immunodeficiency virus type 1. J Virol (1993) 1.70
Epitope-specific protective immunogenicity of chemically synthesized 13-, 18-, and 23-residue peptide fragments of streptococcal M protein. Proc Natl Acad Sci U S A (1984) 1.67
Enhancement of the neonate's nonspecific immunity to Klebsiella infection by muramyl dipeptide, a synthetic immunoadjuvant. Proc Natl Acad Sci U S A (1978) 1.66
Fate of the synthetic immunoadjuvant, muramyl dipeptide (14C-labelled) in the mouse. Int J Immunopharmacol (1979) 1.65
Blastic transformtion of mouse spleen lymphocytes by a water-soluble mitogen extracted from Nocardia. Proc Natl Acad Sci U S A (1974) 1.62
Chemotherapy for patients with locally advanced or metastatic Merkel cell carcinoma. Cancer (1999) 1.61
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
The pyrogenicity of the synthetic adjuvant muramyl dipeptide and two structural analogues. J Infect Dis (1978) 1.59
Immune response to levan. I. Kinetics and ontogeny of anti-levan and anti-inulin antibody response and of expression of cross-reactive idiotype. J Immunol (1978) 1.57
Proteases as mitogens. The Effect of trypsin and pronase on mouse and human lymphocytes. Exp Cell Res (1974) 1.56
Alpha 1-antitrypsin genetic polymorphism in ANCA-positive systemic vasculitis. Kidney Int (1993) 1.56
The globus pallidus in post-encephalitic parkinsonism. J Neurol Sci (1968) 1.55
Isolation of mitogenic and adjuvant active fractions from various species of Nocardiae. Infect Immun (1975) 1.54
Curvature of the spine in post-encephalitic parkinsonism. J Neurol Neurosurg Psychiatry (1965) 1.53
Production of lymphocyte activating factor in the absence of endogenous pyrogen by rabbit or human leukocytes stimulated by a muramyl dipeptide derivative. Int J Immunopharmacol (1982) 1.53
Enhancement of certain biological activities of muramyl dipeptide derivatives after conjugation to a multi-poly(DL-alanine)--poly(L-lysine) carrier. Proc Natl Acad Sci U S A (1979) 1.48
Identification of a new V kappa gene family that is highly expressed in hybridomas from an autoimmune mouse strain. J Immunol (1990) 1.46
Conditions that induce tolerance in mature CD4+ T cells. J Exp Med (1997) 1.45
Thrombosis in the Superior Longitudinal Sinus following Childbirth. Br Med J (1941) 1.44
Sst I RFLP in the human inter-alpha-trypsin inhibitor heavy chain gene ITIH1. Nucleic Acids Res (1988) 1.44
Inter-alpha-trypsin inhibitor proteoglycan family--a group of proteins binding and stabilizing the extracellular matrix. Eur J Biochem (1998) 1.44
Posttraumatic stress disorder among survivors of Cambodian concentration camps. Am J Psychiatry (1984) 1.43
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
Mitogenic effect of a water-soluble extract of Nocardia opaca: a comparative study with some bacterial adjuvants on spleen and peripheral lymphocytes of four mammalian species. J Immunol (1974) 1.40
Enhancement of nonspecific immunity to bacterial infection by cord factor (6,6'-trehalose dimycolate). J Infect Dis (1977) 1.40
Evaluation of commercial amplification kit for detection of Legionella pneumophila in clinical specimens. J Clin Microbiol (1994) 1.40
Microbial degradation of [C14C]polystyrene and 1,3-diphenylbutane. Can J Microbiol (1978) 1.39
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
[Magnetic resonance imaging of tibial periostitis]. J Radiol (1998) 1.38
Evidence for two molecular forms of streptococcal erythrogenic toxin. Conversion to a single form by 2-mercaptoethanol. Eur J Biochem (1969) 1.38
Target cells for the activity of a synthetic adjuvant: muramyl dipeptide. Cell Immunol (1977) 1.36
Preparation and biological properties of water-soluble adjuvant fractions from delipidated cells of Mycobacterium smegmatis and Nocardia opaca. Infect Immun (1973) 1.35
Nonspecific activation of murine spleen cells in vitro by a synthetic immunoadjuvant (N-acetyl-muramyl-L-alanyl-D-isoglutamine). Cell Immunol (1977) 1.35
Effect of indomethacin on increased resistance to bacterial infection and on febrile responses induced by muramyl dipeptide. J Infect Dis (1980) 1.35
Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34
Psychiatry's new role in corrections. Am J Psychiatry (1969) 1.34
Immune response to levan. III. The capacity to produce anti-inulin antibodies and cross-reactive idiotypes appears late in ontogeny. J Immunol (1979) 1.34
A human T-independent B lymphocyte mitogen extracted from Nocardia opaca. J Immunol (1976) 1.33
The macrophage, target cell of the synthetic adjuvant muramyl dipeptide. Eur J Immunol (1978) 1.33
Electrophoretic transfer from polyacrylamide gel to nitrocellulose sheets, a new method to characterize multilocus enzyme genotypes of Klebsiella strains. Appl Environ Microbiol (1994) 1.32
Search for new particles in two-jet final states in 7 TeV proton-proton collisions with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.32
Gamma interferon and interleukin-10 gene expression in innately susceptible and resistant mice during the early phase of Salmonella typhimurium infection. Infect Immun (1996) 1.31
Single clonal origin of a high proportion of Legionella pneumophila serogroup 1 isolates from patients and the environment in the area of Paris, France, over a 10-year period. J Clin Microbiol (1999) 1.31
Plasmodium falciparum: immunogenicity of circumsporozoite protein constructs produced in Escherichia coli. Exp Parasitol (1987) 1.29
Interleukin-4 stimulates cGMP production by IFN-gamma-activated human monocytes. Involvement of the nitric oxide synthase pathway. J Biol Chem (1994) 1.29
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Alpha1-antitrypsin deficiency and liver disease in children: phenotypes, manifestations, and prognosis. Pediatrics (1976) 1.27
Properties of reference Escherichia coli endotoxin and its phthalylated derivative in humans. J Infect Dis (1981) 1.27
Isolation and characterization of a plant cDNA showing homology to animal glutathione peroxidases. Plant Mol Biol (1992) 1.27
Central pyrogenic activity of muramyl dipeptide. J Exp Med (1980) 1.26
In vitro spleen cell responsiveness to various analogs of MDP (N-acetylmuramyl-L-alanyl-D-isoglutamine), a synthetic immunoadjuvant, in MDP high-responder mice. Cell Immunol (1978) 1.26
Successful immunization with a totally synthetic diphtheria vaccine. Proc Natl Acad Sci U S A (1982) 1.26
Blast transformation of rabbit B-derived lymphocytes by a mitogen extracted from Nocardia. J Immunol (1975) 1.25
Enhancement of carrier-specific helper T cell function by the synthetic adjuvant, N-acetyl muramyl-L-alanyl-D-isoglutamine (MDP). J Immunol (1978) 1.25
Apyrogenic, adjuvant-active N-acetylmuramyl-dipeptides. J Med Chem (1982) 1.25
Neonatal treatment with low doses of anti-idiotypic antibody leads to the expression of a silent clone. J Exp Med (1981) 1.24