Published in J Biol Chem on September 15, 1993
Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion. Microbiol Rev (1996) 3.46
A transmembrane guanylyl cyclase (DAF-11) and Hsp90 (DAF-21) regulate a common set of chemosensory behaviors in caenorhabditis elegans. Genetics (2000) 2.90
Guanylyl cyclase structure, function and regulation. Cell Signal (2011) 1.40
Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases. Pharmacol Ther (2010) 1.26
Guanylyl cyclase receptors. Mol Biol Cell (1994) 0.94
Glycosylation of the receptor guanylate cyclase C: role in ligand binding and catalytic activity. Biochem J (2004) 0.92
Current understanding of guanylin peptides actions. ISRN Nephrol (2013) 0.82
Chloride conductance and genetic background modulate the cystic fibrosis phenotype of Delta F508 homozygous twins and siblings. J Clin Invest (2001) 1.63
Less small airway dysfunction in asymptomatic bronchial hyperresponsiveness than in asthma. Allergy (2013) 1.48
A delta F508 mutation in mouse cystic fibrosis transmembrane conductance regulator results in a temperature-sensitive processing defect in vivo. J Clin Invest (1996) 1.42
Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances. J Biol Chem (1993) 1.40
Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation. Proc Natl Acad Sci U S A (1998) 1.31
Activation of the osmo-sensitive chloride conductance involves P21rho and is accompanied by a transient reorganization of the F-actin cytoskeleton. Mol Biol Cell (1996) 1.30
Defective jejunal and colonic salt absorption and alteredNa(+)/H (+) exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice. Pflugers Arch (2008) 1.26
Determinants of mild clinical symptoms in cystic fibrosis patients. Residual chloride secretion measured in rectal biopsies in relation to the genotype. J Clin Invest (1994) 1.23
Characterization of a proton-driven carrier for sialic acid in the lysosomal membrane. Evidence for a group-specific transport system for acidic monosaccharides. J Biol Chem (1989) 1.21
Isotype-specific activation of cystic fibrosis transmembrane conductance regulator-chloride channels by cGMP-dependent protein kinase II. J Biol Chem (1995) 1.20
Isolation of intestinal mucosa cells. Methods Enzymol (1974) 1.15
Regulated trafficking of the CFTR chloride channel. Eur J Cell Biol (2000) 1.13
Ion transport abnormalities in rectal suction biopsies from children with cystic fibrosis. Gastroenterology (1991) 1.12
Expression of cGMP-dependent protein kinase I and phosphorylation of its substrate, vasodilator-stimulated phosphoprotein, in human endothelial cells of different origin. Circ Res (1995) 1.10
Signalling by cGMP-dependent protein kinases. Mol Cell Biochem (1996) 1.07
Genistein activates CFTR Cl- channels via a tyrosine kinase- and protein phosphatase-independent mechanism. Am J Physiol (1997) 1.07
N-terminal myristoylation is required for membrane localization of cGMP-dependent protein kinase type II. J Biol Chem (1996) 1.05
Hypo-osmotic cell swelling activates the p38 MAP kinase signalling cascade. FEBS Lett (1996) 1.05
G-proteins mediate intestinal chloride channel activation. J Biol Chem (1991) 0.99
Heat-stable enterotoxin receptor/guanylyl cyclase C is an oligomer consisting of functionally distinct subunits, which are non-covalently linked in the intestine. J Biol Chem (1994) 0.98
Treatment of the bronchial tree from beginning to end: targeting small airway inflammation in asthma. Allergy (2013) 0.96
Dual role for protein kinase C alpha as a regulator of ion secretion in the HT29cl.19A human colonic cell line. Biochem J (1992) 0.95
Cyclic GMP-dependent protein kinase in intestinal brushborders. Adv Cyclic Nucleotide Res (1981) 0.95
The mechanism of action of Escherichia coli heat-stable toxin. Biochem Soc Trans (1984) 0.92
Atrial natriuretic peptide-stimulated Ca2+ reabsorption in rabbit kidney requires membrane-targeted, cGMP-dependent protein kinase type II. Proc Natl Acad Sci U S A (1999) 0.92
cGMP stimulation of cystic fibrosis transmembrane conductance regulator Cl- channels co-expressed with cGMP-dependent protein kinase type II but not type Ibeta. J Biol Chem (1997) 0.92
Asymmetrical distribution of G-proteins among the apical and basolateral membranes of rat enterocytes. Biochem J (1991) 0.91
Mechanisms by which cyclic nucleotides and other intracellular mediators regulate secretion. Ciba Found Symp (1985) 0.90
Electrophysiological studies of forskolin-induced changes in ion transport in the human colon carcinoma cell line HT-29 cl.19A: lack of evidence for a cAMP-activated basolateral K+ conductance. J Membr Biol (1991) 0.90
New clinical diagnostic procedures for cystic fibrosis in Europe. J Cyst Fibros (2011) 0.90
Serum-induced membrane depolarization in quiescent fibroblasts: activation of a chloride conductance through the G protein-coupled LPA receptor. EMBO J (1996) 0.89
Ca(2+)-mobilizing hormones potentiate hypotonicity-induced activation of ionic conductances in Intestine 407 cells. Am J Physiol (1994) 0.88
Cyclic nucleotide-dependent phosphorylation of intestinal epithelium proteins. Nature (1976) 0.88
Biphasic increase of apical Cl- conductance by muscarinic stimulation of HT-29cl.19A human colon carcinoma cell line: evidence for activation of different Cl- conductances by carbachol and forskolin. J Membr Biol (1992) 0.87
Endogenous type II cGMP-dependent protein kinase exists as a dimer in membranes and can Be functionally distinguished from the type I isoforms. J Biol Chem (1997) 0.86
Phorbol esters stimulate and inhibit Cl- secretion by different mechanisms in a colonic cell line. Am J Physiol (1992) 0.85
Properties of guanylate cyclase and levels of cyclic GMP in rat small intestinal villous and crypt cells. FEBS Lett (1975) 0.85
Alterations in the proteome of the NHERF1 knockout mouse jejunal brush border membrane vesicles. Physiol Genomics (2010) 0.85
Kinetic evidence for the presence of two forms of M2-type pyruvate kinase in rat small intestine. Biochem Biophys Res Commun (1974) 0.83
Regulation of apical Cl- conductance and basolateral K+ conductances by phorbol esters in HT-29cl.19A cells. Am J Physiol (1992) 0.83
Cumene hydroperoxide, an agent inducing lipid peroxidation, and 4-hydroxy-2,3-nonenal, a peroxidation product, cause coronary vasodilatation in perfused rat hearts by a cyclic nucleotide independent mechanism. Cardiovasc Res (1990) 0.82
Chloride and potassium conductances of mouse pancreatic zymogen granules are inversely regulated by a approximately 80-kDa mdr1a gene product. J Biol Chem (1996) 0.82
Regulation of the cell swelling-activated chloride conductance by cholesterol-rich membrane domains. Acta Physiol (Oxf) (2006) 0.82
Osmotic swelling-induced activation of the extracellular-signal-regulated protein kinases Erk-1 and Erk-2 in intestine 407 cells involves the Ras/Raf-signalling pathway. Biochem J (1998) 0.81
Nucleotide-activated chloride channels in lysosomal membranes. Biochem Biophys Res Commun (1992) 0.81
Expression and regulation of chloride channels in neonatal rat cardiomyocytes. Mol Cell Biochem (1996) 0.81
Assessment of CFTR function in homozygous R117H-7T subjects. J Cyst Fibros (2011) 0.80
Value of in vivo electrophysiological measurements to evaluate canine small bowel autotransplants. Gut (1991) 0.80
gamma-Aminobutyric acid production in small and large intestine of normal and germ-free Wistar rats. Influence of food intake and intestinal flora. Gastroenterology (1987) 0.79
Cyclic-GMP- and cyclic-AMP-induced intestinal ion secretion: analysis at the level of brush border membrane vesicles. Adv Cyclic Nucleotide Protein Phosphorylation Res (1984) 0.79
Effect of anisotonic conditions on the transport of hydrophilic model compounds across monolayers of human colonic cell lines. J Pharmacol Exp Ther (1994) 0.79
Modulation of salt permeabilities of intestinal brush-border membrane vesicles by micromolar levels of internal calcium. Biochim Biophys Acta (1986) 0.79
Alterations in the proteome of the NHERF2 knockout mouse jejunal brush border membrane vesicles. Physiol Genomics (2011) 0.78
Self-phosphorylation of cyclic guanosine 3':5'-monophosphate-dependent protein kinase from bovine lung. Effect of cyclic adenosine 3':5'-monophosphate, cyclic guanosine 3':5'-monophosphate and histone. J Biol Chem (1977) 0.78
Regulation of chloride channels in the human colon carcinoma cell line HT29.cl19A. Pflugers Arch (1993) 0.78
Cyclic nucleotide-dependent protein phosphorylation in intestinal epithelium. Kroc Found Ser (1984) 0.78
Regulation of chloride transport in cultured normal and cystic fibrosis keratinocytes. Biochim Biophys Acta (1992) 0.77
Chloride transport in cultured nasal epithelium of cystic fibrosis patients. Pflugers Arch (1990) 0.77
Small airway dysfunction in asymptomatic bronchial hyperresponsiveness and asthma. Allergy (2014) 0.77
On the role of cyclic AMP and Ca2+-calmodulin-dependent phosphorylation in the control of (Ca2+ + Mg2+)-ATPase of cardiac sarcolemma. FEBS Lett (1981) 0.77
Calcium ionophore plus excision induce a large conductance chloride channel in membrane patches of human colon carcinoma cells HT-29cl.19A. Experientia (1993) 0.76
Internal exposure of rats to benzidine derived from orally administered benzidine-based dyes after intestinal azo reduction. Toxicology (1986) 0.75
The value of in vivo electrophysiological measurements for monitoring functional adaptation after massive small bowel resection in the rat. Gut (1993) 0.75
Activation of intestinal chloride channels by GTP-binding regulatory proteins. Adv Second Messenger Phosphoprotein Res (1990) 0.75
Pitfalls in the immunohistochemical localization of the cystic fibrosis transmembrane conductance regulator in paraffin embedded sweat glands. Histochem J (2000) 0.75
Local changes in fractional saturation of cGMP- and cAMP-receptors in intestinal microvilli in response to cholera toxin and heat-stable Escherichia coli toxin. Biochim Biophys Acta (1986) 0.75
Inhibition of mitochondrial-protein synthesis in rat small-intestinal epithelium. Eur J Biochem (1973) 0.75
The cystic fibrosis defect approached from different angles--new perspectives on the gene, the chloride channel, diagnosis and therapy. Eur J Pediatr (1990) 0.75
Characterization of swelling-induced ion transport in HT-29Cl.19A cells. Role of inorganic and organic osmolytes during regulatory volume decrease. Pflugers Arch (1997) 0.75
The role of rectal chloride secretion in childhood constipation. Neurogastroenterol Motil (2011) 0.75
LLC-PK1 cells as a model system to study proximal tubule transport of water and other compounds relevant for renal stone disease. Urol Res (1999) 0.75
Separation of basolateral plasma membranes from smooth endoplasmic reticulum of the rat enterocyte by zonal electrophoresis on density gradients. Biochim Biophys Acta (1980) 0.75
[Expression of the cystic fibrosis gene in the lungs]. Ned Tijdschr Geneeskd (2004) 0.75