PubRank

D Philibert

Author PubWeight™ 43.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Non-steroidal antiandrogens: synthesis and biological profile of high-affinity ligands for the androgen receptor. J Steroid Biochem Mol Biol 1994 1.84
2 RU 38486: potent antiglucocorticoid activity correlated with strong binding to the cytosolic glucocorticoid receptor followed by an impaired activation. J Steroid Biochem 1984 1.46
3 [The effects of an antiprogesterone steroid in women: interruption of the menstrual cycle and of early pregnancy]. C R Seances Acad Sci III 1982 1.26
4 Autoradiographic localization of glucocorticosteroid and progesterone binding sites in the human post-mortem brain. J Steroid Biochem 1986 1.08
5 RU 38486: a potent antiglucocorticoid in vitro and in vivo. J Steroid Biochem 1985 1.07
6 17 alpha-alkynyl-11 beta, 17-dihydroxyandrostane derivatives : a new class of potent glucocorticoids. Steroids 1981 1.01
7 Progesterone and RU486: opposing effects on human sperm. Proc Natl Acad Sci U S A 1994 0.94
8 RU 486. Sci Am 1990 0.93
9 Progesterone binding in the immature mouse and rat uterus. Steroids 1973 0.91
10 Comparative study of estrogen action. Mol Pharmacol 1973 0.90
11 Pharmacological profile of RU 58642, a potent systemic antiandrogen for the treatment of androgen-dependent disorders. J Steroid Biochem Mol Biol 1998 0.89
12 Psychosocial aspects of neoplastic disease: II. Affective and cognitive effects of chemotherapy in cancer patients. Am J Psychiatry 1980 0.89
13 Contragestion by antiprogestin RU 486: a review. Arch Gynecol Obstet 1987 0.87
14 Steroid hormone receptors and pharmacology. J Steroid Biochem 1980 0.87
15 Mechanism of action of an antiprogesterone, RU486, in the rabbit endometrium. Effects of RU486 on the progesterone receptor and on the expression of the uteroglobin gene. Eur J Biochem 1985 0.85
16 Design of ligands for the glucocorticoid and progestin receptors. Biochem Soc Trans 1991 0.85
17 Steroid hormone receptors in human meningiomas, gliomas and brain metastases. J Neurooncol 1983 0.84
18 RU 58841, a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism. J Steroid Biochem Mol Biol 1994 0.84
19 A progesterone metabolite enhances the activity of the GABAA receptor complex at the pituitary level. Eur J Pharmacol 1989 0.82
20 11 beta-amidoalkyl estradiols, a new series of pure antiestrogens. J Steroid Biochem Mol Biol 1992 0.81
21 Properties of the cytoplasmic progestin-binding protein in the rabbit uterus. Endocrinology 1977 0.81
22 11 beta-Amidoalkoxyphenyl estradiols, a new series of pure antiestrogens. J Steroid Biochem Mol Biol 1994 0.81
23 Sequences in the ligand-binding domains of the human androgen and progesterone receptors which determine their distinct ligand identities. J Mol Endocrinol 1997 0.81
24 Residues in the ligand binding domain that confer progestin or glucocorticoid specificity and modulate the receptor transactivation capacity. Mol Endocrinol 2000 0.81
25 Antiglucocorticoid properties of RU 38486 in a differentiated hepatoma cell line. Biochem Pharmacol 1983 0.80
26 Screening for anti-hormones by receptor studies. J Steroid Biochem 1975 0.80
27 Specific progesterone receptors in dimethylbenzanthracene (DMBA)-induced mammary tumors. Steroids 1976 0.80
28 Synthesis of a fluorescent steroid derivative with high affinities for the glucocorticoid and progesterone receptors. Steroids 1994 0.79
29 Autoradiographic localization of glucocorticosteroid binding sites in rat brain after in vivo injection of [3H]RU 28362. Neurosci Lett 1988 0.79
30 RU 58668: further in vitro and in vivo pharmacological data related to its antitumoral activity. J Steroid Biochem Mol Biol 1996 0.79
31 The effect of the antimineralocorticoid RU 28318 on aldosterone biosynthesis in vitro. J Steroid Biochem 1984 0.79
32 RU 58,668, a new pure antiestrogen inducing a regression of human mammary carcinoma implanted in nude mice. J Steroid Biochem Mol Biol 1994 0.79
33 History and perspectives of antiprogestins from the chemist's point of view. Hum Reprod 1994 0.79
34 Regio and stereospecific synthesis of 11 beta-substituted 19-norsteroids. Influence of 11 beta-substitution on progesterone receptor affinity - (1). Steroids 1981 0.79
35 Control of birth in rats by RU 486, an antiprogesterone compound. J Reprod Fertil 1987 0.79
36 Progesterone binding in the immature rabbit and guinea pig uterus. Endocrinology 1974 0.78
37 Progesterone-Progestin receptors. Basic Life Sci 1974 0.78
38 Switching agonistic, antagonistic, and mixed transcriptional responses to 11 beta-substituted progestins by mutation of the progesterone receptor. Mol Endocrinol 1992 0.78
39 Structure-activity relationships of a new family of steroidal aromatase inhibitors. 1. Synthesis and evaluation of a series of analogs related to 19-[(methylthio)methyl]androstenedione (RU54115). J Med Chem 1996 0.78
40 Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: relation of their systemic activity to the formation of a common metabolite. J Steroid Biochem Mol Biol 1994 0.77
41 Fertility control with RU 486. Horm Res 1987 0.77
42 [Effects of an anti-progestin steroid in women: interruption of the menstrual cycle or early pregnancy (author's transl)]. Contracept Fertil Sex (Paris) 1982 0.77
43 Progesterone suppression of pregnancy lymphocytes is not mediated by glucocorticoid effect. Am J Reprod Immunol 1990 0.77
44 Binding of progesterone and R 5020, a highly potent progestin, to human endometrium and myometrium. Contraception 1974 0.77
45 In vitro binding of tritiated glucocorticoids directly on unfixed rat brain sections. J Steroid Biochem 1984 0.76
46 In vitro autoradiographic localization of [3H]corticosterone binding sites in rat hippocampus. Eur J Pharmacol 1984 0.76
47 Synthesis of 11 beta-vinyl-19-norsteroids as potent progestins. Steroids 1982 0.76
48 Synthesis and evaluation of a new series of mechanism-based aromatase inhibitors. J Med Chem 1992 0.76
49 RU 486 development. Science 1990 0.76
50 [Binding affinity to steroid hormone receptors and antiproliferative action on MCF-7 cells of coumarin derivatives and isoflavonoids]. Ann Pharm Fr 1999 0.76
51 Agenesis of the cecum and the ascending and transverse colon in a 12-yer-old cat. Can Vet J 1992 0.75
52 Another study: the patient's perspective. 1989. CANNT J 2008 0.75
53 [Binding of tritiated corticosterone by brain sections of adrenalectomized rats]. C R Seances Acad Sci III 1983 0.75
54 Synthesis and relative binding affinity to steroid receptors and antiproliferative activity on MCF-7 cells of 2,3-disubstituted indenes. Farmaco 1999 0.75
55 Comparison between the interaction of steroids with [35S]TBPS binding to cerebral cortical and to pituitary membranes: correlation with inhibition of prolactin release. Naunyn Schmiedebergs Arch Pharmacol 1992 0.75
56 Corticosteroid receptors in rat hippocampal sections: effect of adrenalectomy and corticosterone replacement. J Steroid Biochem 1986 0.75
57 Cytosolic and nuclear sex steroid receptors in meningioma. Clin Neuropharmacol 1984 0.75
58 Exploration of the therapeutic potential of the antiestrogen RU 58668 in breast cancer treatment. Ann N Y Acad Sci 1995 0.75
59 Paradoxical involvement of glucocorticoid receptors in the aldosterone-induced impairment of ACTH secretion from perifused pituitary glands. J Steroid Biochem 1984 0.75
60 General structure-activity correlations of antihormones. Ann N Y Acad Sci 1995 0.75
61 Steroid binding in the hypothalamus and pituitary. Curr Top Mol Endocrinol 1976 0.75
62 Early glycogenesis in the uterine glandular cells of the rabbit induced by progestins: a quantitative investigation. Cell Tissue Res 1987 0.75
63 Self-inhibition of steroid secretion by amphibian adrenocortical cells is not mediated through glucocorticoid receptors. J Mol Endocrinol 1991 0.75
64 RU 3117 a steroidal compound with high affinity for sigma sites in rat testis membranes. J Steroid Biochem Mol Biol 1996 0.75
65 [The effects of an antiprogesterone steroid in women: interruption of the menstrual cycle and of early pregnancy. Supplementary note]. C R Seances Acad Sci III 1983 0.75