Published in N Engl J Med on June 23, 1994
Nephrolithiasis-associated bone disease: pathogenesis and treatment options. Kidney Int (2010) 2.35
Fortnightly review: Beneficial effects of potassium. BMJ (2001) 1.59
Metabolic acidosis: pathophysiology, diagnosis and management. Nat Rev Nephrol (2010) 1.59
Hypercalciuria associated with high dietary protein intake is not due to acid load. J Clin Endocrinol Metab (2011) 1.54
Nutritional disturbance in acid-base balance and osteoporosis: a hypothesis that disregards the essential homeostatic role of the kidney. Br J Nutr (2013) 1.52
Risk of fracture after radical cystectomy and urinary diversion for bladder cancer. J Clin Oncol (2014) 1.41
Causal assessment of dietary acid load and bone disease: a systematic review & meta-analysis applying Hill's epidemiologic criteria for causality. Nutr J (2011) 1.41
Potassium bicarbonate attenuates the urinary nitrogen excretion that accompanies an increase in dietary protein and may promote calcium absorption. J Clin Endocrinol Metab (2008) 1.19
Dietary acid load: a novel nutritional target in chronic kidney disease? Adv Chronic Kidney Dis (2013) 1.15
Consequences and therapy of the metabolic acidosis of chronic kidney disease. Pediatr Nephrol (2010) 1.10
Association of serum bicarbonate levels with gait speed and quadriceps strength in older adults. Am J Kidney Dis (2011) 1.09
Prevalence and densitometric characteristics of incomplete distal renal tubular acidosis in men with recurrent calcium nephrolithiasis. Urol Res (2011) 1.09
Phosphate decreases urine calcium and increases calcium balance: a meta-analysis of the osteoporosis acid-ash diet hypothesis. Nutr J (2009) 1.05
Effects of rhIGF-I administration on bone turnover during short-term fasting. J Clin Invest (1995) 0.99
Potassium and health. Adv Nutr (2013) 0.98
Improved mineral balance and skeletal metabolism in postmenopausal women treated with potassium bicarbonate. N Engl J Med (1994) 0.95
Protective effects of dietary carotenoids on risk of hip fracture in men: the Singapore Chinese Health Study. J Bone Miner Res (2014) 0.94
A positive association of lumbar spine bone mineral density with dietary protein is suppressed by a negative association with protein sulfur. J Nutr (2008) 0.93
Effect of a supplement rich in alkaline minerals on acid-base balance in humans. Nutr J (2009) 0.93
Current status of bicarbonate in CKD. J Am Soc Nephrol (2014) 0.91
Dietary acid, age, and serum bicarbonate levels among adults in the United States. Clin J Am Soc Nephrol (2013) 0.91
Adherence to a vegetable-fruit-soy dietary pattern or the Alternative Healthy Eating Index is associated with lower hip fracture risk among Singapore Chinese. J Nutr (2014) 0.88
Comparative effects of oral aromatic and branched-chain amino acids on urine calcium excretion in humans. Osteoporos Int (2007) 0.88
Relationship of nutrient intakes and bone mineral density of elderly women in Daegu, Korea. Nutr Res Pract (2007) 0.87
The interaction between dietary protein and bone health. J Bone Miner Metab (2010) 0.86
Comparison of dried plum supplementation and intermittent PTH in restoring bone in osteopenic orchidectomized rats. Osteoporos Int (2007) 0.86
Dietary protein and skeletal health: a review of recent human research. Curr Opin Lipidol (2011) 0.85
Treatment of metabolic acidosis in patients with CKD. Am J Kidney Dis (2013) 0.85
Low urine pH and acid excretion do not predict bone fractures or the loss of bone mineral density: a prospective cohort study. BMC Musculoskelet Disord (2010) 0.83
Bone, acid, and osteoporosis. N Engl J Med (1994) 0.82
Mechanism of urinary calcium regulation by urinary magnesium and pH. J Am Soc Nephrol (2008) 0.82
Do vegetarians have a normal bone mass? Osteoporos Int (2004) 0.81
Optimizing bone health in older adults: the importance of dietary protein. Aging health (2010) 0.81
Serum bicarbonate and bone mineral density in US adults. Am J Kidney Dis (2014) 0.80
Pharmacological inhibition of intracellular calcium release blocks acid-induced bone resorption. Am J Physiol Renal Physiol (2010) 0.80
Bicarbonate therapy improves growth in children with incomplete distal renal tubular acidosis. Pediatr Nephrol (2009) 0.80
Effect of an isoflavones-containing red clover preparation and alkaline supplementation on bone metabolism in ovariectomized rats. Clin Interv Aging (2009) 0.80
Nutrition and bone health projects funded by the UK Food Standards Agency: have they helped to inform public health policy? Br J Nutr (2008) 0.80
The effect of supplementation with alkaline potassium salts on bone metabolism: a meta-analysis. Osteoporos Int (2015) 0.78
Nutritional strategies for skeletal and cardiovascular health: hard bones, soft arteries, rather than vice versa. Open Heart (2016) 0.78
Comparison of correlates of bone mineral density in individuals adhering to lacto-ovo, vegan, or omnivore diets: a cross-sectional investigation. Nutrients (2015) 0.78
Molecular mechanisms and regulation of urinary acidification. Compr Physiol (2014) 0.78
Biochemical and histological assessment of alkali therapy during high animal protein intake in the rat. Bone (2009) 0.77
Dietary potassium intake is beneficial to bone health in a low calcium intake population: the Korean National Health and Nutrition Examination Survey (KNHANES) (2008-2011). Osteoporos Int (2017) 0.76
Dietary acid load, kidney function, osteoporosis, and risk of fractures in elderly men and women. Osteoporos Int (2014) 0.76
Metabolic responses to high protein diet in Korean elite bodybuilders with high-intensity resistance exercise. J Int Soc Sports Nutr (2011) 0.76
[Vegetarian nutrition: Preventive potential and possible risks. Part 1: Plant foods]. Wien Klin Wochenschr (2006) 0.76
Mineral balance in postmenopausal women treated with potassium bicarbonate. N Engl J Med (1994) 0.75
Species-specific responses of N homeostasis and electrolyte handling to low N intake: a comparative physiological approach in a monogastric and a ruminant species. J Comp Physiol B (2013) 0.75
Abnormal distal renal tubular acidification in patients with low bone mass: prevalence and impact of alkali treatment. Urolithiasis (2016) 0.75
Intermittent cyclical etidronate treatment of postmenopausal osteoporosis. N Engl J Med (1990) 4.10
Multiple duplications of yeast hexose transport genes in response to selection in a glucose-limited environment. Mol Biol Evol (1998) 2.90
Noninvasive assessment of bone mineral and structure: state of the art. J Bone Miner Res (1996) 2.47
Prevention of nonvertebral fractures by alendronate. A meta-analysis. Alendronate Osteoporosis Treatment Study Groups. JAMA (1997) 2.46
Estimation of net endogenous noncarbonic acid production in humans from diet potassium and protein contents. Am J Clin Nutr (1998) 2.00
Mesenteric defects as a cause of intestinal volvulus without malrotation and as the possible primary etiology of intestinal atresia. J Pediatr Surg (1994) 1.96
Staphylococcus aureus Agr and Sar global regulators influence internalization and induction of apoptosis. Infect Immun (1998) 1.86
Treatment of painful osteoporotic vertebral fractures with percutaneous vertebroplasty or kyphoplasty. Osteoporos Int (2001) 1.73
Renal tubular acidosis. Mechanisms, classification and implications. N Engl J Med (1969) 1.64
Serious fireworks-related eye injuries. Ophthalmic Epidemiol (2000) 1.59
Dietary intake of phosphorus modulates the circadian rhythm in serum concentration of phosphorus. Implications for the renal production of 1,25-dihydroxyvitamin D. J Clin Invest (1987) 1.59
Impaired renal acidification in patients with hypergammaglobulinemia. Medicine (Baltimore) (1967) 1.55
"Salt-sensitive" essential hypertension in men. Is the sodium ion alone important? N Engl J Med (1987) 1.48
Alendronate treatment of the postmenopausal osteoporotic woman: effect of multiple dosages on bone mass and bone remodeling. Am J Med (1995) 1.48
Genetic contamination of Dahl SS/Jr rats. Impact on studies of salt-sensitive hypertension. Hypertension (1994) 1.48
Normal diet NaCl variation can affect the renal set-point for plasma pH-(HCO3-) maintenance. J Am Soc Nephrol (1990) 1.47
Assessment of vertebral bone mineral density using volumetric quantitative CT. J Comput Assist Tomogr (1999) 1.45
Effect of dietary phosphorus on circulating concentrations of 1,25-dihydroxyvitamin D and immunoreactive parathyroid hormone in children with moderate renal insufficiency. J Clin Invest (1984) 1.44
Grocery store baking soda. A source of sodium bicarbonate in the management of chronic metabolic acidosis. Clin Pediatr (Phila) (1984) 1.43
Diet, evolution and aging--the pathophysiologic effects of the post-agricultural inversion of the potassium-to-sodium and base-to-chloride ratios in the human diet. Eur J Nutr (2001) 1.43
Bisphosphonates: safety and efficacy in the treatment and prevention of osteoporosis. Am Fam Physician (2000) 1.43
Oral intake of phosphorus can determine the serum concentration of 1,25-dihydroxyvitamin D by determining its production rate in humans. J Clin Invest (1986) 1.41
Glutamine synthetase in muscle and kidney. Biochem J (1970) 1.38
Effect of age on blood acid-base composition in adult humans: role of age-related renal functional decline. Am J Physiol (1996) 1.36
Metabolic and physiologic improvements from consuming a paleolithic, hunter-gatherer type diet. Eur J Clin Nutr (2009) 1.35
Physiologic regulation of the serum concentration of 1,25-dihydroxyvitamin D by phosphorus in normal men. J Clin Invest (1989) 1.34
The role of compartmentation in the control of glycolysis. Curr Top Cell Regul (1977) 1.31
1,25-dihydroxyvitamin D3 modulates growth of vascular smooth muscle cells. J Clin Invest (1991) 1.31
The flux of pyruvate in perfused rat heart. Eur J Biochem (1973) 1.27
The clinical diagnosis of osteoporosis: a position statement from the National Bone Health Alliance Working Group. Osteoporos Int (2014) 1.27
Dose-response relationships for alendronate treatment in osteoporotic elderly women. Alendronate Elderly Osteoporosis Study Centers. J Clin Endocrinol Metab (1997) 1.25
The enzymic estimation of glutamate and glutamine. Biochem J (1966) 1.24
Potassium bicarbonate reduces urinary nitrogen excretion in postmenopausal women. J Clin Endocrinol Metab (1997) 1.23
The Zucker fatty rat as a genetic model of obesity and hypertension. Hypertension (1989) 1.21
Renal potassium wasting in renal tubular acidosis (RTA): its occurrence in types 1 and 2 RTA despite sustained correction of systemic acidosis. J Clin Invest (1971) 1.21
Succinate thiokinase in pigeon breast muscle mitochondria. FEBS Lett (1986) 1.19
Attainment and maintenance of normal stature with alkali therapy in infants and children with classic renal tubular acidosis. J Clin Invest (1978) 1.17
Normalization in the fitting of data by iterative methods. Application to tracer kinetics and enzyme kinetics. Biochem J (1973) 1.17
Measurement of aortic blood flow by Doppler echocardiography: day to day variability in normal subjects and applicability in clinical research. J Am Coll Cardiol (1991) 1.16
Amelioration of metabolic acidosis with fludrocortisone therapy in hyporeninemic hypoaldosteronism. N Engl J Med (1977) 1.15
The analysis of kinetic data in biochemistry. A critical evaluation of methods. FEBS Lett (1976) 1.10
Incidence of radiographically evident bone disease, nephrocalcinosis, and nephrolithiasis in various types of renal tubular acidosis. N Engl J Med (1982) 1.09
Studies on the mechanism and kinetics of the 2-oxoglutarate dehydrogenase system from pig heart. Biochem J (1977) 1.09
Succinic thiokinase and metabolic control. Int J Biochem (1981) 1.08
Evidence that the severity of depletion of inorganic phosphate determines the severity of the disturbance of adenine nucleotide metabolism in the liver and renal cortex of the fructose-loaded rat. J Clin Invest (1978) 1.08
In vivo assessment of architecture and micro-finite element analysis derived indices of mechanical properties of trabecular bone in the radius. Osteoporos Int (2002) 1.08
Dietary chloride as a determinant of "sodium-dependent" hypertension. Science (1983) 1.07
Increments in bone mineral density of the lumbar spine and hip and suppression of bone turnover are maintained after discontinuation of alendronate in postmenopausal women. Am J Med (1997) 1.04
Symposium on acid-base homeostasis. Renal acidosis. Kidney Int (1972) 1.03
The effect of insulin and growth hormone on the flux of tracer from labelled lactate in perfused rat heart. Eur J Biochem (1973) 1.02
An experimental renal acidification defect in patients with hereditary fructose intolerance. I. Its resemblance to renal tubular acidosis. J Clin Invest (1968) 1.02
Hot-Pack and 1-MHz Ultrasound Treatments Have an Additive Effect on Muscle Temperature Increase. J Athl Train (1998) 1.01
Worldwide incidence of hip fracture in elderly women: relation to consumption of animal and vegetable foods. J Gerontol A Biol Sci Med Sci (2000) 1.00
Effects of dietary cholesterol and fat saturation on plasma lipoproteins in an ethnically diverse population of healthy young men. J Clin Invest (1995) 0.98
Addition of alendronate to ongoing hormone replacement therapy in the treatment of osteoporosis: a randomized, controlled clinical trial. J Clin Endocrinol Metab (1999) 0.98
Biological variability in Wistar-Kyoto rats. Implications for research with the spontaneously hypertensive rat. Hypertension (1987) 0.98
Relationships between the responses of triglyceride-rich lipoproteins in blood plasma containing apolipoproteins B-48 and B-100 to a fat-containing meal in normolipidemic humans. Proc Natl Acad Sci U S A (1993) 0.97
On the mechanism of renal potassium wasting in renal tubular acidosis associated with the Fanconi syndrome (type 2 RTA). J Clin Invest (1971) 0.97
Quantitative computed tomography: update 1987. Calcif Tissue Int (1987) 0.96
Renal tubular acidosis. N Engl J Med (1981) 0.96
Shouldice hernia repair: results at a teaching institution. Am Surg (1987) 0.96
Evidence for binding of cytoplasmic creatine kinase to structural elements in heart muscle. Nature (1967) 0.96
Calcitonin gene-related peptide levels are elevated in patients with sepsis. Surgery (1990) 0.95
Improved mineral balance and skeletal metabolism in postmenopausal women treated with potassium bicarbonate. N Engl J Med (1994) 0.95
Spinal bone mineral density measured with quantitative CT: effect of region of interest, vertebral level, and technique. Radiology (1990) 0.95
Effect of estrone sulfate on postmenopausal bone loss. Obstet Gynecol (1990) 0.94
The crisis in Bosnia: breaking down barriers. Br Dent J (1993) 0.93
Genetically determined chloride-sensitive hypertension and stroke. Proc Natl Acad Sci U S A (1997) 0.92
Absence of renal fructose-1-phosphate aldolase activity in hereditary fructose intolerance. Nature (1967) 0.92
Monitoring bone resorption in early postmenopausal women by an immunoassay for cross-linked collagen peptides in urine. J Bone Miner Res (1994) 0.91
Cyclical etidronate in the treatment of postmenopausal osteoporosis: efficacy and safety after seven years of treatment. Am J Med (1997) 0.91
Serving native health needs: merging technology and traditional information services. West J Med (2000) 0.91
Endothelin-induced increases in vascular smooth muscle Ca2+ do not depend on dihydropyridine-sensitive Ca2+ channels. J Clin Invest (1989) 0.89
Parathyroidectomy reduces 25-hydroxyvitamin D3-1 alpha-hydroxylase activity in the hypocalcemic vitamin D-deficient chick. J Clin Invest (1977) 0.89
Some examples of the use of computer-produced contour plots in the fitting of enzyme rate equations to reaction-velocity measurements. Biochem J (1972) 0.88
Appropriate use of bone densitometry. Radiology (1989) 0.88
Renal tubular acidosis in infants: the several kinds, including bicarbonate-wasting, classic renal tubular acidosis. J Clin Invest (1972) 0.88
Renal tubular acidosis. Effects of sodium phosphate and sulfate on renal acidification in two patients with renal tubular acidosis. Pediatrics (1965) 0.88
Effect of dopamine on the tubuloglomerular feedback mechanism. Am J Physiol (1990) 0.88
Exaggerated phosphaturic response to circulating parathyroid hormone in patients with familial X-linked hypophosphatemic rickets. J Clin Invest (1976) 0.87
Impaired renal conservation of sodium and chloride during sustained correction of systemic acidosis in patients with type 1, classic renal tubular acidosis. J Clin Invest (1976) 0.87
The concentration of asparagine in the tissues of rats treated with growth hormone. Biochem J (1972) 0.87
Bone mineral content in early-postmenopausal and postmenopausal osteoporotic women: comparison of measurement methods. Radiology (1986) 0.87
Adenovirus infection and childhood intussusception. Am J Dis Child (1992) 0.86
Emerging assets and liabilities of a committee on human welfare and experimentation. N Engl J Med (1970) 0.86
The role of diagnostic laparoscopy in the management of trauma patients: a preliminary assessment. J Trauma (1993) 0.86
NaCl-induced renal vasoconstriction in salt-sensitive African Americans: antipressor and hemodynamic effects of potassium bicarbonate. Hypertension (1999) 0.86
Localization in cardiac muscle of some enzymes related to glutamate metabolism. Histochem J (1975) 0.85
Renal excretion of pseudoephedrine. Clin Pharmacol Ther (1980) 0.85
Hypertension in the recently weaned Dahl salt-sensitive rat despite a diet deficient in sodium chloride. Science (1985) 0.85
Glutamine metabolism in the perfused rat heart. Q J Exp Physiol Cogn Med Sci (1969) 0.84
Vitamin D status regulates 25-hydroxyvitamin D3-1 alpha-hydroxylase and its responsiveness to parathyroid hormone in the chick. J Clin Invest (1985) 0.84
Some rate constants for the phenazine methosulphate-catalysed oxidation of reduced nicotinamide-adenine dinucleotide. Biochem J (1966) 0.84
Calcitonin treatment for central giant cell granulomas of the mandible: report of two cases. J Oral Maxillofac Surg (1999) 0.84
Control points in the citric acid cycle. Biochem Soc Trans (1976) 0.83
Renal fructose-metabolizing enzymes: significance in hereditary fructose intolerance. Science (1969) 0.83
An examination of the association between vertebral deformities, physical disabilities and psychosocial problems. Maturitas (1988) 0.83