PubRank

J B Hibbs

Author PubWeight™ 128.09‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite. Science 1987 8.98
2 L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells. J Immunol 1987 6.93
3 Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr Opin Immunol 1991 6.92
4 Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine. J Immunol 1990 4.62
5 Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism. J Immunol 1990 4.36
6 Interferon-gamma and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages. Eur J Immunol 1988 4.04
7 Differentiation of murine macrophages to express nonspecific cytotoxicity for tumor cells results in L-arginine-dependent inhibition of mitochondrial iron-sulfur enzymes in the macrophage effector cells. J Immunol 1988 3.98
8 Control of carcinogenesis: a possible role for the activated macrophage. Science 1972 3.69
9 Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages. J Clin Invest 1988 3.69
10 EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages. Proc Natl Acad Sci U S A 1990 2.94
11 Macrophage tumor killing: influence of the local environment. Science 1977 2.94
12 Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages. J Clin Invest 1990 2.91
13 Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversible. J Clin Invest 1986 2.76
14 Characterization of the effects of endotoxin on macrophage tumor cell killing. J Immunol 1978 2.65
15 Urinary nitrate excretion in relation to murine macrophage activation. Influence of dietary L-arginine and oral NG-monomethyl-L-arginine. J Immunol 1991 2.60
16 Resistance to murine tumors conferred by chronic infection with intracellular protozoa, Toxoplasma gondii and Besnoitia jellisoni. J Infect Dis 1971 2.58
17 Possible role of macrophage mediated nonspecific cytotoxicity in tumour resistance. Nat New Biol 1972 2.44
18 L-arginine-dependent macrophage effector functions inhibit metabolic activity of Mycobacterium leprae. J Immunol 1991 2.15
19 Macrophage nonimmunologic recognition: target cell factors related to contact inhibition. Science 1973 2.09
20 Nitric oxide produced during murine listeriosis is protective. Infect Immun 1994 1.93
21 Effect of in vivo inhibition of nitric oxide production in murine leishmaniasis. J Immunol 1993 1.88
22 Heterocytolysis by macrophages activated by bacillus Calmette-Guérin: lysosome exocytosis into tumor cells. Science 1974 1.85
23 Macrophage fibrinolytic activity: identification of two pathways of plasmin formation by intact cells and of a plasminogen activator inhibitor. Cell 1982 1.84
24 Injury of neoplastic cells by murine macrophages leads to inhibition of mitochondrial respiration. J Clin Invest 1980 1.82
25 The L-arginine dependent effector mechanism is induced in murine adenocarcinoma cells by culture supernatant from cytotoxic activated macrophages. J Leukoc Biol 1988 1.72
26 Measurement of nitrate and nitrite in biological samples using nitrate reductase and Griess reaction. Methods Enzymol 1996 1.67
27 Discrimination between neoplastic and non-neoplastic cells in vitro by activated macrophages. J Natl Cancer Inst 1974 1.64
28 Iron depletion: possible cause of tumor cell cytotoxicity induced by activated macrophages. Biochem Biophys Res Commun 1984 1.64
29 Endocytosis of red blood cells or haemoglobin by activated macrophages inhibits their tumoricidal effect. Nature 1977 1.55
30 Gamma interferon-induced nitric oxide production reduces Chlamydia trachomatis infectivity in McCoy cells. Infect Immun 1993 1.50
31 Cytokines induce an L-arginine-dependent effector system in nonmacrophage cells. J Leukoc Biol 1988 1.46
32 Modulation of macrophage tumoricidal capability by components of normal serum: a central role for lipid. Science 1977 1.35
33 In vitro nonimmunologic destruction of cells with abnormal growth characteristics by adjuvant activated macrophages. Proc Soc Exp Biol Med 1972 1.30
34 Assembly and regulation of NADPH oxidase and nitric oxide synthase. Curr Opin Immunol 1994 1.24
35 Aconitases: a class of metalloproteins highly sensitive to nitric oxide synthesis. Methods Enzymol 1996 1.19
36 The macrophage as an antineoplastic surveillance cell: biological perspectives. J Reticuloendothel Soc 1978 1.15
37 The role of nitrogen oxides as effector molecules of parasite killing. Parasitol Today 1990 1.15
38 Modulation of macrophage tumoricidal capability by polyene antibiotics: support for membrane lipid as a regulatory determinant of macrophage function. Proc Natl Acad Sci U S A 1978 1.14
39 Nitric oxide production during murine Lyme disease: lack of involvement in host resistance or pathology. Infect Immun 1995 1.11
40 Adjuvant induced resistance to tumor development in mice. Proc Soc Exp Biol Med 1972 1.10
41 Antiparasitic effects of nitric oxide in an in vitro murine model of Chlamydia trachomatis infection and an in vivo murine model of Leishmania major infection. Immunol Ser 1994 1.08
42 Activated macrophages as cytotoxic effector cells. Transplantation 1975 1.07
43 Parana, a new Tacaribe complex virus from Paraguay. Arch Gesamte Virusforsch 1970 1.03
44 Macrophage nitric oxide synthesis delays progression of ultraviolet light-induced murine skin cancers. Cancer Res 1993 1.02
45 Effects of trypan blue treatment on the immune responses of mice. Infect Immun 1977 0.99
46 DNA virus-transformed hamster cell--host effector cell interactions: level of resistance to cytolysis correlated with tumorigenicity. Int J Cancer 1982 0.97
47 Use of N-acetyl cysteine to increase intracellular glutathione during the induction of antitumor responses by IL-2. J Immunol 1994 0.96
48 Role of activated macrophages in nonspecific resistance to neoplasia. J Reticuloendothel Soc 1976 0.95
49 Induction of iron-derived EPR signals in murine cancers by nitric oxide. Evidence for multiple intracellular targets. J Biol Chem 1994 0.94
50 Interaction of macrophages with tumor cells. Adv Exp Med Biol 1976 0.92
51 Coordinate expression of macrophage procoagulant and fibrinolytic activity in vitro and in vivo. J Immunol 1983 0.91
52 In vitro modulation of macrophage tumoricidal activity: partial characterization of a macrophage-activating factor(s) in supernatants of NaIO4-treated peritoneal cells. J Reticuloendothel Soc 1979 0.88
53 Nitric oxide production in murine leishmaniasis: correlation of progressive infection with increasing systemic synthesis of nitric oxide. Am J Trop Med Hyg 1996 0.88
54 Activated macrophage conditioned medium: identification of the soluble factors inducing cytotoxicity and the L-arginine dependent effector mechanism. J Leukoc Biol 1991 0.86
55 Cloned macrophages can be induced to kill tumor cells. J Reticuloendothel Soc 1978 0.85
56 Resistance of simian virus 40-transformed hamster cells to the cytolytic effect of activated macrophages: a possible factor in species-specific viral oncogenicity. Proc Natl Acad Sci U S A 1980 0.83
57 Nitric oxide production during adjuvant-induced and collagen-induced arthritis. Arthritis Rheum 1996 0.82
58 Nitric oxide synthesis contributes to IL-2-induced antitumor responses against intraperitoneal Meth A tumor. J Immunol 1995 0.82
59 Modulation of plasminogen activator secretion by activated macrophages: influence of serum factors and correlation with tumoricidal potential. Proc Natl Acad Sci U S A 1979 0.80
60 N omega -monomethyl-L-arginine inhibits nitric oxide production in murine cardiac allografts but does not affect graft rejection. Biochim Biophys Acta 1994 0.80
61 Activated macrophage-mediated cytotoxicity: use of the in vitro cytotoxicity assay for study of bioenergetic and biochemical changes that develop in tumor target cells. Methods Enzymol 1986 0.80
62 Aberrant oxygen metabolism in neoplastic cells injured by cytotoxic macrophages. Adv Exp Med Biol 1985 0.79
63 Enhanced macrophage tumoricidal activity and tumor suppression or regression caused by heat-killed Candida albicans. J Natl Cancer Inst 1979 0.78
64 Activated macrophage mediated cytotoxicity for transformed target cells. Adv Exp Med Biol 1982 0.78
65 Modulation of the tumoricidal function of activated macrophages by bacterial endotoxin and mammalian macrophage activation factor (s). Adv Exp Med Biol 1979 0.78
66 Activated macrophages as cytotoxic effector cells. II. Requirement for local persistence of inducing antigen. Transplantation 1975 0.77
67 Nitric oxide synthesis in patients with advanced HIV infection. Clin Exp Immunol 1994 0.77
68 High-output nitric oxide: weapon against infection? Trends Microbiol 1996 0.76
69 Effectiveness and toxicity of protracted nitric oxide synthesis inhibition during IL-2 treatment of mice. J Immunother Emphasis Tumor Immunol 1995 0.75
70 Water as a biomaterial. Trans Am Soc Artif Intern Organs 1973 0.75
71 Nitric oxide production during adjuvant-induced arthritis is associated with tumor necrosis factor genotype. Transplant Proc 1995 0.75
72 A relationship between SV40-transformed cell susceptibility to macrophage killing and tumor induction in rodents. Adv Exp Med Biol 1981 0.75