Published in Crit Rev Toxicol on January 01, 1993
Heavy metal toxicity and the environment. EXS (2012) 2.28
Exposure to hexavalent chromium resulted in significantly higher tissue chromium burden compared with trivalent chromium following similar oral doses to male F344/N rats and female B6C3F1 mice. Toxicol Sci (2010) 1.57
Carcinogenic lead chromate induces DNA double-strand breaks in human lung cells. Mutat Res (2005) 1.40
Chromium in drinking water: sources, metabolism, and cancer risks. Chem Res Toxicol (2011) 1.34
Hexavalent chromium is carcinogenic to F344/N rats and B6C3F1 mice after chronic oral exposure. Environ Health Perspect (2008) 1.29
Ascorbate acts as a highly potent inducer of chromate mutagenesis and clastogenesis: linkage to DNA breaks in G2 phase by mismatch repair. Nucleic Acids Res (2006) 1.28
Enhanced exopolymer production and chromium stabilization in Pseudomonas putida unsaturated biofilms. Appl Environ Microbiol (2006) 1.26
The role of oxygen free radicals in occupational and environmental lung diseases. Environ Health Perspect (1997) 1.24
Application of the U.S. EPA mode of action Framework for purposes of guiding future research: a case study involving the oral carcinogenicity of hexavalent chromium. Toxicol Sci (2010) 1.00
Cr(VI) induces mitochondrial-mediated and caspase-dependent apoptosis through reactive oxygen species-mediated p53 activation in JB6 Cl41 cells. Toxicol Appl Pharmacol (2010) 0.99
Chromium and genomic stability. Mutat Res (2011) 0.94
Oxidative stress, DNA damage, and antioxidant enzyme activity induced by hexavalent chromium in Sprague-Dawley rats. Environ Toxicol (2009) 0.92
Exposure to nickel, chromium, or cadmium causes distinct changes in the gene expression patterns of a rat liver derived cell line. PLoS One (2011) 0.91
Repression of miR-143 mediates Cr (VI)-induced tumor angiogenesis via IGF-IR/IRS1/ERK/IL-8 pathway. Toxicol Sci (2013) 0.90
Potassium dichromate induced cytotoxicity, genotoxicity and oxidative stress in human liver carcinoma (HepG2) cells. Int J Environ Res Public Health (2009) 0.90
Luteolin inhibits Cr(VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways. Toxicol Appl Pharmacol (2014) 0.90
Characterization of gene expression changes associated with MNNG, arsenic, or metal mixture treatment in human keratinocytes: application of cDNA microarray technology. Environ Health Perspect (2002) 0.87
Distribution of metals in the edible plants grown at Jajmau, Kanpur (India) receiving treated tannery wastewater: relation with physico-chemical properties of the soil. Environ Monit Assess (2006) 0.85
Monitoring human lymphocytic DNA-protein cross-links as biomarkers of biologically active doses of chromate. Environ Health Perspect (1996) 0.84
Reduction with glutathione is a weakly mutagenic pathway in chromium(VI) metabolism. Chem Res Toxicol (2008) 0.83
Reactive oxygen species mediate Cr(VI)-induced carcinogenesis through PI3K/AKT-dependent activation of GSK-3β/β-catenin signaling. Toxicol Appl Pharmacol (2013) 0.83
Synthesis of 4-acetamido-2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate and 4-acetamido-(2,2,6,6-tetramethyl-piperidin-1-yl)oxyl and their use in oxidative reactions. Nat Protoc (2013) 0.82
FANCD2 monoubiquitination and activation by hexavalent chromium [Cr(VI)] exposure: activation is not required for repair of Cr(VI)-induced DSBs. Mutat Res (2006) 0.81
The effects of chromium(VI) on the thioredoxin system: implications for redox regulation. Free Radic Biol Med (2012) 0.81
Effect of supplementation with chromium picolinate on antibody titers to 5-hydroxymethyl uracil. Eur J Epidemiol (1998) 0.80
Carcinogen-induced, free radical-mediated reduction in microsomal membrane fluidity: reversal by indole-3-propionic acid. J Bioenerg Biomembr (2001) 0.80
Biological monitoring of hexavalent chromium and serum levels of the senescence biomarker apolipoprotein J/Clusterin in welders. Bioinorg Chem Appl (2008) 0.79
The dual roles of c-Jun NH2-terminal kinase signaling in Cr(VI)-induced apoptosis in JB6 cells. Toxicol Sci (2010) 0.79
CrVI exposure and biomarkers: Cr in erythrocytes in relation to exposure and polymorphisms of genes encoding anion transport proteins. Biomarkers (2008) 0.78
Hexavalent chromium induces chromosome instability in human urothelial cells. Toxicol Appl Pharmacol (2016) 0.77
The cytotoxicity of chromium in osteoblasts: effects on macromolecular synthesis. J Mater Sci Mater Med (2002) 0.77
Edaravone mitigates hexavalent chromium-induced oxidative stress and depletion of antioxidant enzymes while estrogen restores antioxidant enzymes in the rat ovary in F1 offspring. Biol Reprod (2014) 0.76
Lead and other metals in play kit and craft items composed of vinyl and leather. Am J Public Health (1997) 0.75
Local and Systemic Changes Associated with Long-term, Percutaneous, Static Implantation of Titanium Alloys in Rhesus Macaques (Macaca mulatta). Comp Med (2017) 0.75
Transcriptomic analysis of cultured whale skin cells exposed to hexavalent chromium [Cr(VI)]. Aquat Toxicol (2013) 0.75
Urate oxidase knockdown decreases oxidative stress in a murine hepatic cell line. Oxid Med Cell Longev (2010) 0.75
Effects of chromic chloride on chick embryo fibroblast viability. Toxicol Rep (2015) 0.75
Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family. Genes Dev (2001) 3.59
The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin. Nat Genet (2001) 3.01
Diabetes management in a health maintenance organization. Efficacy of care management using cluster visits. Diabetes Care (1999) 2.52
Gastrulation in Drosophila: the formation of the ventral furrow and posterior midgut invaginations. Development (1991) 2.41
A role for Drosophila SMC4 in the resolution of sister chromatids in mitosis. Curr Biol (2001) 2.19
Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens. Mol Cell Biol (1995) 2.14
Types of nerves in the enteric nervous system. Neuroscience (1980) 2.08
Water-stable fluorophores, produced by reaction with aldehyde solutions, for the histochemical localization of catechol- and indolethylamines. Histochemistry (1977) 2.06
The peristaltic reflex: an analysis of the nerve pathways and their pharmacology. Naunyn Schmiedebergs Arch Pharmacol (1976) 2.04
Quantitative analysis of peristalsis in the guinea-pig small intestine using spatio-temporal maps. J Physiol (1999) 2.00
Fast detection of arbitrarily shaped disease clusters. Stat Med (2006) 1.89
Impact of intraoperative ultrasonography in laparoscopic liver surgery. Surg Endosc (2006) 1.80
Cap43, a novel gene specifically induced by Ni2+ compounds. Cancer Res (1998) 1.69
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Co-localization of calcitonin gene-related peptide-like immunoreactivity with substance P in cutaneous, vascular and visceral sensory neurons of guinea pigs. Neurosci Lett (1985) 1.66
Apamin distinguishes two types of relaxation mediated by enteric nerves in the guinea-pig gastrointestinal tract. Naunyn Schmiedebergs Arch Pharmacol (1986) 1.65
Evidence for the release of endogenous substance P from intestinal nerves. Naunyn Schmiedebergs Arch Pharmacol (1979) 1.61
The sites of action of 5-hydroxytryptamine in nerve-muscle preparations from the guinea-pig small intestine and colon. Br J Pharmacol (1979) 1.59
The nervous release and the action of substances which affect intestinal muscle through neither adrenoreceptors nor cholinoreceptors. Philos Trans R Soc Lond B Biol Sci (1973) 1.59
Mast, a conserved microtubule-associated protein required for bipolar mitotic spindle organization. EMBO J (2000) 1.57
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors. Carcinogenesis (1999) 1.54
The adrenergic innervation of the gastrointestinal tract. Ergeb Physiol (1974) 1.53
Neurons with 5-hydroxytryptamine-like immunoreactivity in the enteric nervous system: their projections in the guinea-pig small intestine. Neuroscience (1982) 1.52
A simple, sensitive assay to detect DNA-protein crosslinks in intact cells and in vivo. Carcinogenesis (1992) 1.49
Spontaneous release of acetylcholine from autonomic nerves in the bladder. Br J Pharmacol (2009) 1.47
Choline acetyltransferase- and peptide immunoreactivity of submucous neurons in the small intestine of the guinea-pig. Cell Tissue Res (1984) 1.47
In vivo localisation of the mitotic POLO kinase shows a highly dynamic association with the mitotic apparatus during early embryogenesis in Drosophila. Biol Cell (1999) 1.47
Voltage dependence of macroscopic and unitary currents of gap junction channels formed by mouse connexin50 expressed in rat neuroblastoma cells. J Physiol (1999) 1.46
The role of oxidative processes in metal carcinogenesis. Chem Res Toxicol (1992) 1.44
Identification and immunohistochemistry of cholinergic and non-cholinergic circular muscle motor neurons in the guinea-pig small intestine. Neuroscience (1991) 1.44
Prolonged pudendal nerve terminal motor latency is associated with decreased resting and squeeze pressures in the intact anal sphincter. Colorectal Dis (2013) 1.40
Comprehensive investigation in patients affected by sperm macrocephaly and globozoospermia. Andrology (2015) 1.40
Somatostatin is present in a subpopulation of noradrenergic nerve fibres supplying the intestine. Neuroscience (1984) 1.40
Carcinogenic nickel induces genes involved with hypoxic stress. Cancer Res (2000) 1.40
Carcinogenic metals induce hypoxia-inducible factor-stimulated transcription by reactive oxygen species-independent mechanism. Cancer Res (2000) 1.38
The receptor tyrosine kinase ARK mediates cell aggregation by homophilic binding. Mol Cell Biol (1995) 1.36
The use of glyoxylic acid for the fluorescence histochemical demonstration of peripheral stores of noradrenaline and 5-hydroxytryptamine in whole mounts. Histochemistry (1975) 1.35
Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control. Science (1991) 1.35
A pharmacological analysis of the neuronal circuitry involved in distension-evoked enteric excitatory reflex. Neuroscience (1990) 1.35
Carcinogenicity assessment of selected nickel compounds. Toxicol Appl Pharmacol (1997) 1.34
Nickel induces increased oxidants in intact cultured mammalian cells as detected by dichlorofluorescein fluorescence. Toxicol Appl Pharmacol (1993) 1.32
The role of enteric inhibitory motoneurons in peristalsis in the isolated guinea-pig small intestine. J Physiol (1994) 1.32
Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer. Cancer Res (2000) 1.32
Enteric motor and interneuronal circuits controlling motility. Neurogastroenterol Motil (2004) 1.32
Substance P-like immunoreactivity in nerves associated with the vascular system of guinea-pigs. Neuroscience (1982) 1.30
Inhibitory innervation of the gut. Gastroenterology (1973) 1.30
Toxicity and carcinogenicity of nickel compounds. Crit Rev Toxicol (1989) 1.26
Somatostatin is contained in and released from cholinergic nerves in the heart of the toad Bufo marinus. Neuroscience (1982) 1.26
Neurons with 5-hydroxytryptamine-like immunoreactivity in the enteric nervous system: their visualization and reactions to drug treatment. Neuroscience (1982) 1.25
DNA methylation, heterochromatin and epigenetic carcinogens. Mutat Res (1997) 1.25
The origins, pathways and terminations of neurons with VIP-like immunoreactivity in the guinea-pig small intestine. Neuroscience (1983) 1.25
On the possibility that an indoleamine is a neurotransmitter in the gastrointestinal tract. Biochem Pharmacol (1979) 1.23
Measurement of the electron charge asymmetry in inclusive W production in pp collisions at sqrt[s]=7 TeV. Phys Rev Lett (2012) 1.23
Emotions and stress increase respiratory resistance in asthma. Psychosom Med (2000) 1.23
Initiation of peristalsis by circumferential stretch of flat sheets of guinea-pig ileum. J Physiol (1999) 1.23
Glutathione and free amino acids form stable complexes with DNA following exposure of intact mammalian cells to chromate. Carcinogenesis (1995) 1.21
Distribution and projections of nerves with enkephalin-like immunoreactivity in the guinea-pig small intestine. Neuroscience (1983) 1.20
Semen analysis following allogeneic bone marrow transplantation. Additional data for evidence-based counselling. Bone Marrow Transplant (2002) 1.20
Search for new physics in the multijet and missing transverse momentum final state in proton-proton collisions at √s = 7 TeV. Phys Rev Lett (2012) 1.19
Azimuthal anisotropy of charged particles at high transverse momenta in Pb-Pb collisions at sqrt[s(NN)] = 2.76 TeV. Phys Rev Lett (2012) 1.19
The role of ascending excitatory and descending inhibitory pathways in peristalsis in the isolated guinea-pig small intestine. J Physiol (1994) 1.19
Cr(III)-mediated crosslinks of glutathione or amino acids to the DNA phosphate backbone are mutagenic in human cells. Nucleic Acids Res (1998) 1.18
Distribution, pathways and reactions to drug treatment of nerves with neuropeptide Y- and pancreatic polypeptide-like immunoreactivity in the guinea-pig digestive tract. Cell Tissue Res (1983) 1.18
Analysis of residual amino acid--DNA crosslinks induced in intact cells by nickel and chromium compounds. Carcinogenesis (1992) 1.18
Neurochemically similar myenteric and submucous neurons directly traced to the mucosa of the small intestine. Cell Tissue Res (1985) 1.17
gamma-Aminobutyric acid stimulates intrinsic inhibitory and excitatory nerves in the guinea-pig intestine. Eur J Pharmacol (1980) 1.17
Morphology and distribution of intrinsic adrenergic neurones in the proximal colon of the guinea-pig. Z Zellforsch Mikrosk Anat (1971) 1.17
Cell cycle-specific activity of type I and type II cyclic adenosine 3':5'-monophosphate-dependent protein kinases in Chinese hamster ovary cells. J Biol Chem (1976) 1.17
The contribution of founder mutations to early-onset breast cancer in French-Canadian women. Clin Genet (2009) 1.17
Projections of substance P-containing neurons within the guinea-pig small intestine. Neuroscience (1981) 1.16
Analysis of motor patterns in the isolated guinea-pig large intestine by spatio-temporal maps. Neurogastroenterol Motil (2001) 1.15
Roles of hydrogen peroxide in thyroid physiology and disease. J Clin Endocrinol Metab (2007) 1.15
Intrinsic and extrinsic inhibitory synaptic inputs to submucous neurones of the guinea-pig small intestine. J Physiol (1988) 1.15
Substance P enteric neurons mediate non-cholinergic transmission to the circular muscle of the guinea-pig intestine. Naunyn Schmiedebergs Arch Pharmacol (1985) 1.14
Immunohistochemical localization of polypeptides in peripheral autonomic nerves using whole mount preparations. Histochemistry (1980) 1.14
Accommodation mediated by enteric inhibitory reflexes in the isolated guinea-pig small intestine. J Physiol (1994) 1.14
Choline acetyltransferase immunoreactivity in the human small and large intestine. Gastroenterology (1996) 1.12
Electrophysiological analysis of projections of enteric inhibitory motoneurones in the guinea-pig small intestine. J Physiol (1986) 1.12
Nonrandom chromosomal alterations in nickel-transformed Chinese hamster embryo cells. Cancer Res (1989) 1.12
Long aboral projections of Dogiel type II, AH neurons within the myenteric plexus of the guinea pig small intestine. J Neurosci (1995) 1.11
Immunohistochemical identification of cholinergic neurons in the myenteric plexus of guinea-pig small intestine. Neuroscience (1991) 1.11
Distribution of enteric neurons showing immunoreactivity for substance P in the guinea-pig ileum. Neuroscience (1980) 1.10
Phagocytosis, cellular distribution, and carcinogenic activity of particulate nickel compounds in tissue culture. Cancer Res (1981) 1.10
Search for a W' or techni-ρ decaying into WZ in pp Collisions at sqrt[s] = 7 TeV. Phys Rev Lett (2012) 1.10
Mutagenic responses of nickel oxides and nickel sulfides in Chinese hamster V79 cell lines at the xanthine-guanine phosphoribosyl transferase locus. Mutat Res (1993) 1.10
Carcinogenic activity of particulate nickel compounds is proportional to their cellular uptake. Science (1980) 1.09
Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy. Phys Rev Lett (2012) 1.09
Investigations of nerve populations influencing ion transport that can be stimulated electrically, by serotonin and by a nicotinic agonist. Naunyn Schmiedebergs Arch Pharmacol (1985) 1.09
Body size and flight distance in stingless bees (Hymenoptera: Meliponini): inference of flight range and possible ecological implications. Braz J Biol (2004) 1.08
Excitatory and inhibitory motor reflexes in the isolated guinea-pig stomach. J Physiol (1997) 1.08
Ultrastructural localization of nitric oxide synthase immunoreactivity in guinea-pig enteric neurons. Brain Res (1992) 1.08
Search for supersymmetry at the LHC in events with jets and missing transverse energy. Phys Rev Lett (2011) 1.08
Safety and efficacy of laparoscopic radiofrequency ablation of hepatocellular carcinoma in patients with liver cirrhosis. Surg Endosc (2003) 1.07
[Intravascular ultrasound in cardiology]. Vnitr Lek (2000) 1.07