Published in Mol Cell Biol on February 01, 1995
TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer. Adv Cancer Res (2008) 3.63
Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival. Proc Natl Acad Sci U S A (2006) 2.05
Retracted A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control. EMBO J (2005) 1.72
A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation. Mol Cell Biol (1999) 1.62
TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine. PLoS Pathog (2013) 1.53
Differential activation of the Ras/extracellular-signal-regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinase. Mol Cell Biol (1996) 1.50
Axl-dependent signalling: a clinical update. Clin Sci (Lond) (2012) 1.28
Molecular aspects of renal cell carcinoma: a review. Am J Cancer Res (2010) 1.25
Gas6 induces growth, beta-catenin stabilization, and T-cell factor transcriptional activation in contact-inhibited C57 mammary cells. Mol Cell Biol (2001) 1.21
Expression of receptor tyrosine kinase Axl and its ligand Gas6 in rheumatoid arthritis: evidence for a novel endothelial cell survival pathway. Am J Pathol (1999) 1.19
The receptor tyrosine kinase Axl is an essential regulator of prostate cancer proliferation and tumor growth and represents a new therapeutic target. Oncogene (2012) 1.17
Novel mechanism for gonadotropin-releasing hormone neuronal migration involving Gas6/Ark signaling to p38 mitogen-activated protein kinase. Mol Cell Biol (2002) 1.17
Mitogenic signals and transforming potential of Nyk, a newly identified neural cell adhesion molecule-related receptor tyrosine kinase. Mol Cell Biol (1995) 1.13
Retracted Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum. Mol Cell Biol (2005) 1.10
Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development. Proc Natl Acad Sci U S A (2005) 1.08
AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer. Clin Cancer Res (2013) 1.06
Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration. Mol Endocrinol (2008) 1.06
Localization and signaling of the receptor protein tyrosine kinase Tyro3 in cortical and hippocampal neurons. Neuroscience (2007) 1.05
Up-regulation of soluble Axl and Mer receptor tyrosine kinases negatively correlates with Gas6 in established multiple sclerosis lesions. Am J Pathol (2009) 1.03
A baculovirus superinfection system: efficient vehicle for gene transfer into Drosophila S2 cells. J Virol (2000) 1.02
Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion. Mol Cell Biol (2014) 1.02
Axl as a mediator of cellular growth and survival. Oncotarget (2014) 0.99
Growth arrest-specific gene 6 (gas6) and vascular hemostasis. Adv Nutr (2012) 0.97
Identification of domains responsible for ubiquitin-dependent degradation of dMyc by glycogen synthase kinase 3beta and casein kinase 1 kinases. Mol Cell Biol (2009) 0.94
Gas6 and the receptor tyrosine kinase Axl in clear cell renal cell carcinoma. PLoS One (2009) 0.92
TAM receptor tyrosine kinases: expression, disease and oncogenesis in the central nervous system. Brain Res (2013) 0.91
Hypothalamic but not pituitary or ovarian defects underlie the reproductive abnormalities in Axl/Tyro3 null mice. Mol Cell Endocrinol (2011) 0.87
Cancer-derived mutations in the fibronectin III repeats of PTPRT/PTPrho inhibit cell-cell aggregation. Cell Commun Adhes (2009) 0.86
Cataract- and lens-specific upregulation of ARK receptor tyrosine kinase in Emory mouse cataract. Invest Ophthalmol Vis Sci (2002) 0.84
AXL and MET crosstalk to promote gonadotropin releasing hormone (GnRH) neuronal cell migration and survival. Mol Cell Endocrinol (2013) 0.83
Tyro3 receptor tyrosine kinases in the heterogeneity of apoptotic cell uptake. Front Biosci (Landmark Ed) (2009) 0.79
Axl receptor tyrosine kinase is up-regulated in metformin resistant prostate cancer cells. Oncotarget (2015) 0.78
Axl Receptor Axis: A New Therapeutic Target in Lung Cancer. J Thorac Oncol (2016) 0.78
Giving AXL the axe: targeting AXL in human malignancy. Br J Cancer (2017) 0.77
Functional consequences of AXL sequence variants in hypogonadotropic hypogonadism. J Clin Endocrinol Metab (2014) 0.77
Negative feedback regulation of AXL by miR-34a modulates apoptosis in lung cancer cells. RNA (2015) 0.76
AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer. Oncotarget (2016) 0.76
Protein S drives oral squamous cell carcinoma tumorigenicity through regulation of AXL. Oncotarget (2017) 0.75
The Gas6/TAM System and Multiple Sclerosis. Int J Mol Sci (2016) 0.75
Highly Sensitive, Engineered Magnetic Nanosensors to Investigate the Ambiguous Activity of Zika Virus and Binding Receptors. Sci Rep (2017) 0.75
The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science (1988) 35.59
Integrins: versatility, modulation, and signaling in cell adhesion. Cell (1992) 34.06
Cadherin cell adhesion receptors as a morphogenetic regulator. Science (1991) 13.78
The immunoglobulin superfamily--domains for cell surface recognition. Annu Rev Immunol (1988) 12.87
Cell lines derived from late embryonic stages of Drosophila melanogaster. J Embryol Exp Morphol (1972) 9.58
VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell (1990) 8.87
The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. Development (1988) 8.84
Human GM-CSF: molecular cloning of the complementary DNA and purification of the natural and recombinant proteins. Science (1985) 8.72
Signal transduction from the extracellular matrix. J Cell Biol (1993) 7.64
Integrins and other cell adhesion molecules. FASEB J (1990) 7.28
Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing. Science (1987) 6.48
High-expression vectors with multiple cloning sites for construction of trpE fusion genes: pATH vectors. Methods Enzymol (1991) 6.25
Growth factor signaling by receptor tyrosine kinases. Neuron (1992) 5.70
PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science (1990) 5.28
Vectors for Drosophila P-element-mediated transformation and tissue culture transfection. Gene (1988) 5.18
The kit ligand: a cell surface molecule altered in steel mutant fibroblasts. Cell (1990) 4.43
Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule. J Cell Biol (1991) 3.91
Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule. Cell (1989) 3.81
Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells. Nucleic Acids Res (1988) 3.66
axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. Mol Cell Biol (1991) 3.57
Analysis of the gene encoding the largest subunit of RNA polymerase II in Drosophila. Mol Gen Genet (1989) 2.75
Morphoregulatory molecules. Biochemistry (1988) 2.75
The axonal glycoprotein TAG-1 is an immunoglobulin superfamily member with neurite outgrowth-promoting activity. Cell (1990) 2.36
Homophilic binding of PTP mu, a receptor-type protein tyrosine phosphatase, can mediate cell-cell aggregation. J Cell Biol (1993) 2.04
A novel putative tyrosine kinase receptor with oncogenic potential. Oncogene (1991) 1.81
Role of myelin P0 protein as a homophilic adhesion molecule. Nature (1990) 1.68
Receptor tyrosine phosphatase R-PTP-kappa mediates homophilic binding. Mol Cell Biol (1994) 1.64
Neuron-glia cell adhesion molecule interacts with neurons and astroglia via different binding mechanisms. J Cell Biol (1988) 1.59
Fasciclin III: a novel homophilic adhesion molecule in Drosophila. Cell (1989) 1.52
Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin. Proc Natl Acad Sci U S A (1992) 1.30
Differential splicing generates a nervous system-specific form of Drosophila neuroglian. Neuron (1990) 1.26
A putative receptor tyrosine kinase with unique structural topology. Oncogene (1991) 1.24
Structure, expression, and activity of Tyro 3, a neural adhesion-related receptor tyrosine kinase. Oncogene (1994) 1.24
Dtrk, a Drosophila gene related to the trk family of neurotrophin receptors, encodes a novel class of neural cell adhesion molecule. EMBO J (1992) 1.21
Cloning of the cDNA for a novel receptor tyrosine kinase, Sky, predominantly expressed in brain. Oncogene (1994) 1.11
rse, a novel receptor-type tyrosine kinase with homology to Axl/Ufo, is expressed at high levels in the brain. J Biol Chem (1994) 1.11
The murine ufo receptor: molecular cloning, chromosomal localization and in situ expression analysis. Oncogene (1992) 1.01
brt, a mouse gene encoding a novel receptor-type protein-tyrosine kinase, is preferentially expressed in the brain. Oncogene (1994) 0.94
Quantitative analysis of intercellular adhesive specificity in freshly explanted and cultured cells. J Cell Biol (1981) 0.91
A retrovirus carrying the K-fgf oncogene induces diffuse meningeal tumors and soft-tissue fibrosarcomas. Mol Cell Biol (1993) 0.82
Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3. Genes Dev (1995) 5.42
An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family. Cell (1987) 3.78
Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family. Genes Dev (2001) 3.59
Premature of chromosome condensation in a ts DNA- mutant of BHK cells. Cell (1978) 3.55
Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites. Mol Cell Biol (1997) 3.34
The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin. Nat Genet (2001) 3.01
Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2. Proc Natl Acad Sci U S A (1998) 2.78
Loss of integrated viral DNA sequences in polyomatransformed cells is associated with an active viral A function. Cell (1979) 2.61
State of the viral DNA in rat cells transformed by polyoma virus. I. Virus rescue and the presence of nonintergrated viral DNA molecules. J Virol (1976) 2.53
Diabetes management in a health maintenance organization. Efficacy of care management using cluster visits. Diabetes Care (1999) 2.52
Gastrulation in Drosophila: the formation of the ventral furrow and posterior midgut invaginations. Development (1991) 2.41
Fibroblast growth factor receptor is a portal of cellular entry for herpes simplex virus type 1. Science (1990) 2.40
Targeted disruption of the FGF2 gene does not prevent choroidal neovascularization in a murine model. Am J Pathol (1998) 2.33
A role for Drosophila SMC4 in the resolution of sister chromatids in mitosis. Curr Biol (2001) 2.19
Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens. Mol Cell Biol (1995) 2.14
Types of nerves in the enteric nervous system. Neuroscience (1980) 2.08
Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts. J Cell Biol (2000) 2.08
Water-stable fluorophores, produced by reaction with aldehyde solutions, for the histochemical localization of catechol- and indolethylamines. Histochemistry (1977) 2.06
Modulation of the activity of multiple transcriptional activation domains by the DNA binding domains mediates the synergistic action of Sox2 and Oct-3 on the fibroblast growth factor-4 enhancer. J Biol Chem (2000) 2.04
The peristaltic reflex: an analysis of the nerve pathways and their pharmacology. Naunyn Schmiedebergs Arch Pharmacol (1976) 2.04
Quantitative analysis of peristalsis in the guinea-pig small intestine using spatio-temporal maps. J Physiol (1999) 2.00
FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway. Genes Dev (1999) 1.94
Mutation causing temperature-sensitive expression of cell transformation by a tumor virus (SV40-3T3 mouse cells-growth control). Proc Natl Acad Sci U S A (1972) 1.92
Radiation target size of the lytic and the transforming ability of polyoma virus. Proc Natl Acad Sci U S A (1965) 1.91
A murine fibroblast growth factor (FGF) receptor expressed in CHO cells is activated by basic FGF and Kaposi FGF. Proc Natl Acad Sci U S A (1990) 1.90
Fast detection of arbitrarily shaped disease clusters. Stat Med (2006) 1.89
Properties and uses of human-mouse hybrid cell lines. Nature (1968) 1.82
Impact of intraoperative ultrasonography in laparoscopic liver surgery. Surg Endosc (2006) 1.80
Coevolution of HMG domains and homeodomains and the generation of transcriptional regulation by Sox/POU complexes. J Cell Physiol (2001) 1.79
Polyoma large T antigen regulates the integration of viral DNA sequences into the genome of transformed cells. Cell (1981) 1.78
Temperature sensitive mutants of BHK cells affected in cell cycle progression. J Cell Physiol (1977) 1.76
Processing, secretion, and biological properties of a novel growth factor of the fibroblast growth factor family with oncogenic potential. Mol Cell Biol (1988) 1.69
Cap43, a novel gene specifically induced by Ni2+ compounds. Cancer Res (1998) 1.69
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas. Oncogene (2011) 1.66
Co-localization of calcitonin gene-related peptide-like immunoreactivity with substance P in cutaneous, vascular and visceral sensory neurons of guinea pigs. Neurosci Lett (1985) 1.66
Compensation by fibroblast growth factor 1 (FGF1) does not account for the mild phenotypic defects observed in FGF2 null mice. Mol Cell Biol (2000) 1.65
Apamin distinguishes two types of relaxation mediated by enteric nerves in the guinea-pig gastrointestinal tract. Naunyn Schmiedebergs Arch Pharmacol (1986) 1.65
Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis. Dev Biol (1990) 1.64
Sodium salicylate induces apoptosis via p38 mitogen-activated protein kinase but inhibits tumor necrosis factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activation. Proc Natl Acad Sci U S A (1997) 1.64
Infection of thymidine kinase-deficient BHK cells with polyoma virus. Nature (1966) 1.63
State of the viral DNA in rat cells transformed by polyma virus. II. Identification of the cells containing nonintegrated viral DNA and the effect of viral mutations. J Virol (1977) 1.62
Interaction between a novel F9-specific factor and octamer-binding proteins is required for cell-type-restricted activity of the fibroblast growth factor 4 enhancer. Mol Cell Biol (1994) 1.61
Evidence for the release of endogenous substance P from intestinal nerves. Naunyn Schmiedebergs Arch Pharmacol (1979) 1.61
Sequences in the polyomavirus DNA regulatory region involved in viral DNA replication and early gene expression. J Virol (1985) 1.60
Suppression of production of mouse 28S ribosomal RNA in mouse-human hybrids segregating mouse chromosomes. Proc Natl Acad Sci U S A (1977) 1.60
Multiple monoclonal B cell expansions and c-myc oncogene rearrangements in acquired immune deficiency syndrome-related lymphoproliferative disorders. Implications for lymphomagenesis. J Exp Med (1986) 1.60
The sites of action of 5-hydroxytryptamine in nerve-muscle preparations from the guinea-pig small intestine and colon. Br J Pharmacol (1979) 1.59
The nervous release and the action of substances which affect intestinal muscle through neither adrenoreceptors nor cholinoreceptors. Philos Trans R Soc Lond B Biol Sci (1973) 1.59
Heparin increases the affinity of basic fibroblast growth factor for its receptor but is not required for binding. J Biol Chem (1994) 1.58
Mast, a conserved microtubule-associated protein required for bipolar mitotic spindle organization. EMBO J (2000) 1.57
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors. Carcinogenesis (1999) 1.54
Mechanisms of chromium carcinogenicity and toxicity. Crit Rev Toxicol (1993) 1.53
The adrenergic innervation of the gastrointestinal tract. Ergeb Physiol (1974) 1.53
Neurons with 5-hydroxytryptamine-like immunoreactivity in the enteric nervous system: their projections in the guinea-pig small intestine. Neuroscience (1982) 1.52
Expression and function of FGF-4 in peri-implantation development in mouse embryos. Development (1994) 1.51
A temperature-sensitive mutation affecting 28S ribosomal RNA production in mammalian cells. Proc Natl Acad Sci U S A (1973) 1.49
A simple, sensitive assay to detect DNA-protein crosslinks in intact cells and in vivo. Carcinogenesis (1992) 1.49
Analysis of a method for selecting temperature-sensitive mutants of BHK cells. Somatic Cell Genet (1978) 1.48
A temperature-sensitive cell cycle mutant of the BHK cell line. J Cell Physiol (1974) 1.47
Choline acetyltransferase- and peptide immunoreactivity of submucous neurons in the small intestine of the guinea-pig. Cell Tissue Res (1984) 1.47
Spontaneous release of acetylcholine from autonomic nerves in the bladder. Br J Pharmacol (2009) 1.47
In vivo localisation of the mitotic POLO kinase shows a highly dynamic association with the mitotic apparatus during early embryogenesis in Drosophila. Biol Cell (1999) 1.47
Voltage dependence of macroscopic and unitary currents of gap junction channels formed by mouse connexin50 expressed in rat neuroblastoma cells. J Physiol (1999) 1.46
The role of oxidative processes in metal carcinogenesis. Chem Res Toxicol (1992) 1.44
Identification and immunohistochemistry of cholinergic and non-cholinergic circular muscle motor neurons in the guinea-pig small intestine. Neuroscience (1991) 1.44
The interaction of polyoma virus with mouse-hamster somatic hybrid cells. Virology (1970) 1.42
Origin of the thymidine kinase induced by polyoma virus in productively infected cells. J Virol (1969) 1.41
Prolonged pudendal nerve terminal motor latency is associated with decreased resting and squeeze pressures in the intact anal sphincter. Colorectal Dis (2013) 1.40
Comprehensive investigation in patients affected by sperm macrocephaly and globozoospermia. Andrology (2015) 1.40
Somatostatin is present in a subpopulation of noradrenergic nerve fibres supplying the intestine. Neuroscience (1984) 1.40
Carcinogenic nickel induces genes involved with hypoxic stress. Cancer Res (2000) 1.40
Activation of FGF receptors by mutations in the transmembrane domain. Oncogene (1997) 1.38
Isolation of a rearranged human transforming gene following transfection of Kaposi sarcoma DNA. Proc Natl Acad Sci U S A (1987) 1.38
Amplification of integrated viral DNA sequences in polyoma virus-transformed cells. Proc Natl Acad Sci U S A (1980) 1.38
Signaling through the ARK tyrosine kinase receptor protects from apoptosis in the absence of growth stimulation. Oncogene (1997) 1.38
Carcinogenic metals induce hypoxia-inducible factor-stimulated transcription by reactive oxygen species-independent mechanism. Cancer Res (2000) 1.38
STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation in mice overexpressing FGF2. Development (2001) 1.36
Temperature sensitive mutants of BHK 21 cells. Nat New Biol (1972) 1.36
Temperature-sensitive mutations in animal cells. Adv Cancer Res (1977) 1.36
Adenovirus E1a proteins repress expression from polyomavirus early and late promoters. Mol Cell Biol (1986) 1.36
The use of glyoxylic acid for the fluorescence histochemical demonstration of peripheral stores of noradrenaline and 5-hydroxytryptamine in whole mounts. Histochemistry (1975) 1.35
A pharmacological analysis of the neuronal circuitry involved in distension-evoked enteric excitatory reflex. Neuroscience (1990) 1.35
Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control. Science (1991) 1.35
Carcinogenicity assessment of selected nickel compounds. Toxicol Appl Pharmacol (1997) 1.34
Nickel induces increased oxidants in intact cultured mammalian cells as detected by dichlorofluorescein fluorescence. Toxicol Appl Pharmacol (1993) 1.32
The role of enteric inhibitory motoneurons in peristalsis in the isolated guinea-pig small intestine. J Physiol (1994) 1.32
Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer. Cancer Res (2000) 1.32
Enteric motor and interneuronal circuits controlling motility. Neurogastroenterol Motil (2004) 1.32
Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin. Proc Natl Acad Sci U S A (1992) 1.30
Substance P-like immunoreactivity in nerves associated with the vascular system of guinea-pigs. Neuroscience (1982) 1.30
Inhibitory innervation of the gut. Gastroenterology (1973) 1.30
Molecular cloning of a gene that is necessary for G1 progression in mammalian cells. Proc Natl Acad Sci U S A (1987) 1.29
Amplification and excision of integrated polyoma DNA sequences require a functional origin of replication. Cell (1984) 1.26
Somatostatin is contained in and released from cholinergic nerves in the heart of the toad Bufo marinus. Neuroscience (1982) 1.26
Toxicity and carcinogenicity of nickel compounds. Crit Rev Toxicol (1989) 1.26
Regulation of polyomavirus late promoter activity by viral early proteins. J Virol (1986) 1.26
DNA methylation, heterochromatin and epigenetic carcinogens. Mutat Res (1997) 1.25
The origins, pathways and terminations of neurons with VIP-like immunoreactivity in the guinea-pig small intestine. Neuroscience (1983) 1.25