Published in Brain Res Dev Brain Res on October 15, 1993
Midkine, a heparin-binding cytokine with multiple roles in development, repair and diseases. Proc Jpn Acad Ser B Phys Biol Sci (2010) 1.16
Midkine: a promising molecule for drug development to treat diseases of the central nervous system. Curr Pharm Des (2011) 1.04
The effects of early exercise on brain damage and recovery after focal cerebral infarction in rats. Acta Physiol (Oxf) (2011) 1.01
Measuring midkine: the utility of midkine as a biomarker in cancer and other diseases. Br J Pharmacol (2014) 0.87
Midkine, heparin-binding growth factor, blocks kainic acid-induced seizure and neuronal cell death in mouse hippocampus. BMC Neurosci (2010) 0.87
The midkine family of growth factors: diverse roles in nervous system formation and maintenance. Br J Pharmacol (2014) 0.86
Midkine in repair of the injured nervous system. Br J Pharmacol (2014) 0.85
Midkine and cytoplasmic maturation of mammalian oocytes in the context of ovarian follicle physiology. Br J Pharmacol (2014) 0.82
Midkine and Pleiotrophin Concentrations in Amniotic Fluid in Healthy and Complicated Pregnancies. PLoS One (2016) 0.76
Multiple system atrophy: the application of genetics in understanding etiology. Clin Auton Res (2015) 0.75
Improvement of radiotherapy-induced lacrimal gland injury by induced pluripotent stem cell-derived conditioned medium via MDK and inhibition of the p38/JNK pathway. Int J Mol Sci (2014) 0.75
Midkine's Role in Cardiac Pathology. J Cardiovasc Dev Dis (2017) 0.75
A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell (2000) 17.61
ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway. Nature (2000) 5.55
Crystal structure of DNA photolyase from Escherichia coli. Science (1995) 4.21
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage. Genes Dev (2001) 4.06
Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes. Nat Biotechnol (1998) 3.28
Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas. Cancer Res (1998) 3.20
Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates. Nat Genet (1998) 2.42
Structural studies of two ovalbumin glycopeptides in relation to the endo-beta-N-acetylglucosaminidase specificity. J Biol Chem (1975) 2.23
Putative blue-light photoreceptors from Arabidopsis thaliana and Sinapis alba with a high degree of sequence homology to DNA photolyase contain the two photolyase cofactors but lack DNA repair activity. Biochemistry (1995) 2.14
Prognostic factors for progression-free and overall survival with sunitinib targeted therapy and with cytokine as first-line therapy in patients with metastatic renal cell carcinoma. Ann Oncol (2010) 2.06
Endo-beta-N-acetylglucosaminidase acting on carbohydrate moieties of glycoproteins. Purification and properties of the enzyme from Diplococcus pneumoniae. J Biol Chem (1974) 1.99
cDNA cloning and sequencing of a new gene intensely expressed in early differentiation stages of embryonal carcinoma cells and in mid-gestation period of mouse embryogenesis. Biochem Biophys Res Commun (1988) 1.95
Evaluation of precipitation and direct methods for HDL-cholesterol assay by HPLC. Clin Chem (1997) 1.95
A null mutation in basigin, an immunoglobulin superfamily member, indicates its important roles in peri-implantation development and spermatogenesis. Dev Biol (1998) 1.94
Double-stranded RNA unwinding and modifying activity is detected ubiquitously in primary tissues and cell lines. Mol Cell Biol (1990) 1.89
Physical and functional interactions between Pim-1 kinase and Cdc25A phosphatase. Implications for the Pim-1-mediated activation of the c-Myc signaling pathway. J Biol Chem (1999) 1.83
Internalization of lectins in neuronal GERL. J Cell Biol (1977) 1.76
Fractionation of glycopeptides by affinity column chromatography on concanavalin A-sepharose. J Biochem (1975) 1.72
Potential differentiation of human mesenchymal stem cell transplanted in rat corpus cavernosum toward endothelial or smooth muscle cells. Int J Impot Res (2007) 1.72
Differential expression of pleiotrophin and midkine in advanced neuroblastomas. Cancer Res (1995) 1.72
Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics. Carcinogenesis (1998) 1.70
Focal lesion in the splenium of the corpus callosum in epileptic patients: antiepileptic drug toxicity? AJNR Am J Neuroradiol (1999) 1.68
Molecular recognition of the identity-determinant set of isoleucine transfer RNA from Escherichia coli. J Mol Biol (1994) 1.68
Multiple sclerosis associated with duplicated CMT1A: a report of two cases. J Neurol Neurosurg Psychiatry (1997) 1.67
Needle-tract implantation in hepatocellular carcinoma: frequency and CT findings after biopsy with a 19.5-gauge automated biopsy gun. Abdom Imaging (2000) 1.65
Cyclooxygenase-2 inhibitor induces apoptosis and enhances cytotoxicity of various anticancer agents in non-small cell lung cancer cell lines. Clin Cancer Res (2000) 1.64
A comparative split-face study of photodynamic therapy with indocyanine green and indole-3-acetic acid for the treatment of acne vulgaris. Br J Dermatol (2011) 1.63
Midkine inhibits caspase-dependent apoptosis via the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase in cultured neurons. J Neurochem (1999) 1.63
Radiological response predicts survival following transarterial chemoembolisation in patients with unresectable hepatocellular carcinoma. Aliment Pharmacol Ther (2012) 1.60
A new antimitotic substance, FR182877. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo) (2000) 1.57
Antithyroid antibodies in the CSF: their role in the pathogenesis of Hashimoto's encephalopathy. Neurology (2003) 1.57
Syndecan-4 deficiency impairs focal adhesion formation only under restricted conditions. J Biol Chem (2000) 1.55
A new family of heparin-binding growth/differentiation factors: increased midkine expression in Wilms' tumor and other human carcinomas. Cancer Res (1993) 1.55
Expression of desmoglein I and plakoglobin in skin carcinomas. J Cutan Pathol (2000) 1.53
Therapeutic effect of transcatheter oily chemoembolization therapy for encapsulated nodular hepatocellular carcinoma: CT and pathologic findings. Radiology (1992) 1.53
In situ visualization of ultraviolet-light-induced DNA damage repair in locally irradiated human fibroblasts. J Invest Dermatol (2001) 1.52
Dural arteriovenous fistulas with aggressive course: clinical and angiographic correlations in two patients. Neurol Sci (2005) 1.51
Dysplastic nodules in liver cirrhosis: evaluation of hemodynamics with CT during arterial portography and CT hepatic arteriography. Radiology (2000) 1.50
Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics. Carcinogenesis (2001) 1.49
Occlusive myocardial infarction: investigation of bis-gadolinium mesoporphyrins-enhanced T1-weighted MR imaging in a cat model. Radiology (2001) 1.47
A receptor-like protein-tyrosine phosphatase PTPzeta/RPTPbeta binds a heparin-binding growth factor midkine. Involvement of arginine 78 of midkine in the high affinity binding to PTPzeta. J Biol Chem (1999) 1.46
Tau in cerebrospinal fluid: a potential diagnostic marker in Alzheimer's disease. Ann Neurol (1995) 1.46
Complete antithrombin deficiency in mice results in embryonic lethality. J Clin Invest (2000) 1.44
Subcellular localization of N-acetylglucosaminide beta 1----4 galactosyltransferase revealed by immunoelectron microscopy. J Histochem Cytochem (1991) 1.42
Erythropoietin and erythropoietin receptors in human CNS neurons, astrocytes, microglia, and oligodendrocytes grown in culture. J Neuropathol Exp Neurol (2001) 1.41
Impact of final coronary flow velocity reserve on late outcome following stent implantation. Eur Heart J (2002) 1.41
Midkine is involved in neutrophil infiltration into the tubulointerstitium in ischemic renal injury. J Immunol (2001) 1.40
String-plucking as a mechanism of chordal rupture during balloon mitral valvuloplasty using inoue balloon catheter. Catheter Cardiovasc Interv (1999) 1.39
Midkine, a retinoic acid-inducible growth/differentiation factor: immunochemical evidence for the function and distribution. Dev Biol (1993) 1.39
Increased midkine gene expression in human gastrointestinal cancers. Jpn J Cancer Res (1995) 1.39
Neointima formation in a restenosis model is suppressed in midkine-deficient mice. J Clin Invest (2000) 1.37
Acquisition of certain streptomycin-resistant (str) mutations enhances antibiotic production in bacteria. Antimicrob Agents Chemother (1998) 1.37
Endocytosis of cholera toxin into neuronal GERL. Proc Natl Acad Sci U S A (1978) 1.37
Association of hepatitis C virus particles with immunoglobulin: a mechanism for persistent infection. J Gen Virol (1995) 1.36
Internalization of neuronal plasma membrane ricin receptors into the Golgi apparatus. Exp Cell Res (1975) 1.36
Serum midkine levels are increased in patients with various types of carcinomas. Br J Cancer (2000) 1.34
Suppression of octahedral tilts and associated changes in electronic properties at epitaxial oxide heterostructure interfaces. Phys Rev Lett (2010) 1.33
Midkine induces the transformation of NIH3T3 cells. Br J Cancer (1997) 1.33
Necrotizing lymphadenitis: a review of clinicopathological, immunohistochemical and ultrastructural studies. Hematol Oncol (1991) 1.32
Pain and motor complications in Parkinson's disease. J Neurol Neurosurg Psychiatry (2006) 1.31
A retinoic acid responsive gene MK found in the teratocarcinoma system is expressed in spatially and temporally controlled manner during mouse embryogenesis. J Cell Biol (1990) 1.31
Human neural stem cells: electrophysiological properties of voltage-gated ion channels. Neuroreport (2002) 1.30
Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis. Development (1995) 1.30
Segregation of human neural stem cells in the developing primate forebrain. Science (2001) 1.29
Cell-surface glycopeptides: growth-dependent changes in the carbohydrate-peptide linkage region. J Mol Biol (1973) 1.29
Cloning and characterization of a gene (UVR3) required for photorepair of 6-4 photoproducts in Arabidopsis thaliana. Nucleic Acids Res (1998) 1.29
Evidence for lack of DNA photoreactivating enzyme in humans. Proc Natl Acad Sci U S A (1993) 1.29
Diagnostic dilemma of pseudoprogression in the treatment of newly diagnosed glioblastomas: the role of assessing relative cerebral blood flow volume and oxygen-6-methylguanine-DNA methyltransferase promoter methylation status. AJNR Am J Neuroradiol (2011) 1.29
Salivary gland tumors: evaluation with two-phase helical CT. Radiology (2000) 1.29
Modification of chitosan to improve its hypocholesterolemic capacity. Biosci Biotechnol Biochem (1999) 1.28
Phosphodiesterase: overview of protein structures, potential therapeutic applications and recent progress in drug development. Cell Mol Life Sci (2005) 1.28
Syndecan-4 deficiency leads to high mortality of lipopolysaccharide-injected mice. J Biol Chem (2001) 1.26
Identification by large-scale screening of phytochrome-regulated genes in etiolated seedlings of Arabidopsis using a fluorescent differential display technique. Plant Physiol (2000) 1.24
ATM--a key determinant of multiple cellular responses to irradiation. Acta Oncol (2001) 1.23
Recognition of IgG by Fc receptor and complement: effects of glycosidase digestion. Biochem Biophys Res Commun (1977) 1.23
Tissue culture analysis of neurogenesis. II. Lipid-free medium retards myelination in mouse spinal cord cultures. Brain Res (1978) 1.22
Reticulocalbin, a novel endoplasmic reticulum resident Ca(2+)-binding protein with multiple EF-hand motifs and a carboxyl-terminal HDEL sequence. J Biol Chem (1993) 1.22
Abnormalities of sensory and memory functions in mice lacking Bsg gene. Biochem Biophys Res Commun (1997) 1.22
Antisense oligodeoxynucleotide targeted to Midkine, a heparin-binding growth factor, suppresses tumorigenicity of mouse rectal carcinoma cells. Cancer Res (2001) 1.22
Midkine, a retinoic acid-inducible heparin-binding cytokine in inflammatory responses: chemotactic activity to neutrophils and association with inflammatory synovitis. J Biochem (1997) 1.21
New structural characteristic of the large glycopeptides from transformed cells. Nature (1976) 1.21
Alcohol and aldehyde dehydrogenase genotypes and drinking behavior in Japanese. Alcohol Clin Exp Res (1996) 1.21
Expression of basigin, a member of the immunoglobulin superfamily, in the mouse central nervous system. Neurosci Res (1998) 1.20
The immunodepressive effect of infectious bursal disease virus in chickens. Avian Dis (1974) 1.20
Rhabdoid meningioma: clinical features and MR imaging findings in 15 patients. AJNR Am J Neuroradiol (2007) 1.20
Disruption of the midkine gene (Mdk) resulted in altered expression of a calcium binding protein in the hippocampus of infant mice and their abnormal behaviour. Genes Cells (1998) 1.20