Published in Cancer Res on February 01, 1994
Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia. J Exp Med (2010) 1.39
The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1). J Biol Chem (2012) 1.38
Ethyleneglycol-bis-(beta-aminoethylether)tetraacetate as a blood anticoagulant: preservation of antigen-presenting cell function and antigen-specific proliferative response of peripheral blood mononuclear cells from stored blood. Clin Diagn Lab Immunol (2000) 1.00
The influence of iron chelators on the accumulation of protoporphyrin IX in 5-aminolaevulinic acid-treated cells. Br J Cancer (1996) 0.98
Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1. J Biol Chem (2011) 0.98
The iron chelator Dp44mT inhibits hepatocellular carcinoma metastasis via N-Myc downstream-regulated gene 2 (NDRG2)/gp130/STAT3 pathway. Oncotarget (2014) 0.96
Novel near-infrared fluorescent integrin-targeted DFO analogue. Bioconjug Chem (2007) 0.96
Identification of the di-pyridyl ketone isonicotinoyl hydrazone (PKIH) analogues as potent iron chelators and anti-tumour agents. Br J Pharmacol (2003) 0.95
The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells. J Biol Chem (2014) 0.94
Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells. Br J Cancer (2013) 0.92
Targeting cancer by binding iron: Dissecting cellular signaling pathways. Oncotarget (2015) 0.91
The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1. Oncotarget (2015) 0.91
The iron chelator deferoxamine causes activated hepatic stellate cells to become quiescent and to undergo apoptosis. J Gastroenterol (2007) 0.84
The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways. J Biol Chem (2015) 0.82
Aminolevulinic Acid-Based Tumor Detection and Therapy: Molecular Mechanisms and Strategies for Enhancement. Int J Mol Sci (2015) 0.82
Quantitative analysis of the anti-proliferative activity of combinations of selected iron-chelating agents and clinically used anti-neoplastic drugs. PLoS One (2014) 0.82
Lipophilic aroylhydrazone chelator HNTMB and its multiple effects on ovarian cancer cells. BMC Cancer (2010) 0.81
Enhancement of 5-aminolevulinic acid-based fluorescence detection of side population-defined glioma stem cells by iron chelation. Sci Rep (2017) 0.79
Restoring the secretory function of irradiation-damaged salivary gland by administrating deferoxamine in mice. PLoS One (2014) 0.78
Differential regulation of iron chelator-induced IL-8 synthesis via MAP kinase and NF-kappaB in immortalized and malignant oral keratinocytes. BMC Cancer (2007) 0.77
Desferrithiocin is a more potent antineoplastic agent than desferrioxamine. Br J Pharmacol (2002) 0.76
Imaging PEG-like nanoprobes in tumor, transient ischemia, and inflammatory disease models. Bioconjug Chem (2015) 0.76
Novel immunosuppressive agent caerulomycin A exerts its effect by depleting cellular iron content. Br J Pharmacol (2015) 0.75
Differential targeting of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by chelators with anti-proliferative activity in a range of tumor cell-types. Oncotarget (2015) 0.75
Ironing Out the Unconventional Mechanisms of Iron Acquisition and Gene Regulation in Chlamydia. Front Cell Infect Microbiol (2017) 0.75
Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n. Science (1991) 5.99
Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons. N Engl J Med (1994) 4.74
Fragile X genotype characterized by an unstable region of DNA. Science (1991) 4.33
Long-term follow-up results of a randomized drug abuse prevention trial in a white middle-class population. JAMA (1995) 3.98
Competency development in public health leadership. Am J Public Health (2000) 3.84
Preventing adolescent drug abuse through a multimodal cognitive-behavioral approach: results of a 3-year study. J Consult Clin Psychol (1990) 2.81
CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF. Cell (1993) 2.73
Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells. Hum Mol Genet (2000) 2.56
Physical activity and minority women: a qualitative study. Health Educ Behav (1998) 2.55
The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells. Biochim Biophys Acta (1997) 2.38
A refined physical map of the long arm of human chromosome 16. Genomics (1991) 2.15
Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron. Blood (1999) 2.13
Assignment of anonymous DNA probes to specific intervals of human chromosomes 16 and X. Hum Genet (1989) 2.10
Pyridoxal isonicotinoyl hydrazone and its analogs: potential orally effective iron-chelating agents for the treatment of iron overload disease. J Lab Clin Med (1998) 2.03
Predicate-argument structure as a link between linguistic and nonlinguistic representations. Brain Lang (1990) 2.02
Fragile X syndrome without CCG amplification has an FMR1 deletion. Nat Genet (1992) 1.91
A new DNA marker tightly linked to the fragile X locus (FRAXA). Science (1989) 1.88
Heritable fragile sites on human chromosomes. V. A new class of fragile site requiring BrdU for expression. Am J Hum Genet (1980) 1.88
bcl-w, a novel member of the bcl-2 family, promotes cell survival. Oncogene (1996) 1.87
Fragile sites still breaking. Trends Genet (1998) 1.86
Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells. Proc Natl Acad Sci U S A (1999) 1.86
GeneKeyDB: a lightweight, gene-centric, relational database to support data mining environments. BMC Bioinformatics (2005) 1.83
Public health response for the 1996 Olympic Games. JAMA (1998) 1.80
Neurotoxicity of glucocorticoids in the primate brain. Horm Behav (1994) 1.79
Congenital malformations associated with a ring 4 chromosome. J Med Genet (1969) 1.73
Identification of a hypoxia response element in the transferrin receptor gene. J Biol Chem (1999) 1.72
A cognitive-behavioral approach to substance abuse prevention. Addict Behav (1984) 1.69
The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization. J Immunol (1994) 1.63
Extramural prevention research at the Centers for Disease Control and Prevention. Public Health Rep (2001) 1.61
Molecular and biological characterization of human 4-1BB and its ligand. Eur J Immunol (1994) 1.59
Human chromosomal fragile site FRA16B is an amplified AT-rich minisatellite repeat. Cell (1997) 1.55
A natural variant of the cysteine protease virulence factor of group A Streptococcus with an arginine-glycine-aspartic acid (RGD) motif preferentially binds human integrins alphavbeta3 and alphaIIbbeta3. Proc Natl Acad Sci U S A (1999) 1.53
The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents. Blood (1995) 1.53
Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34. EMBO J (1994) 1.52
Evaluation of a primary care counselling service in Dorset. Br J Gen Pract (1998) 1.45
Superantigens - powerful modifiers of the immune system. Mol Med Today (2000) 1.43
The false consensus effect: predicting adolescents' tobacco use from normative expectations. Psychol Rep (1992) 1.43
Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1. Nucleic Acids Res (1994) 1.42
Validation of recombinant Sendai virus in a non-natural host model. Gene Ther (2010) 1.42
Bovine latent transforming growth factor beta 1-binding protein 2: molecular cloning, identification of tissue isoforms, and immunolocalization to elastin-associated microfibrils. Mol Cell Biol (1995) 1.42
Medial paraspinal muscle electromyography: techniques of examination. Arch Phys Med Rehabil (1993) 1.40
Association of a chromosome deletion syndrome with a fragile site within the proto-oncogene CBL2. Nature (1995) 1.38
A cognitive-behavioral approach to substance abuse prevention: one-year follow-up. Addict Behav (1990) 1.38
Providing support to others and well-being in later life. J Gerontol (1992) 1.38
Reassessment of two apparent deletions of chromosome 16p to an ins(11;16) and a t(1;16) by chromosome painting. Ann Genet (1990) 1.34
The common fragile site in band q27 of the human X chromosome is not coincident with the fragile X. Clin Genet (1990) 1.33
The mouse CD69 gene. Structure, expression, and mapping to the NK gene complex. J Immunol (1994) 1.33
Characterisation of a new rare fragile site easily confused with the fragile X. Hum Mol Genet (1992) 1.31
A psychosocial approach to smoking prevention for urban black youth. Public Health Rep (1990) 1.31
Predictors of smoking prevalence among New York Latino youth. Am J Public Health (1992) 1.29
Excess thymidine induces folate sensitive fragile sites. Am J Med Genet (1985) 1.29
Correlates and predictors of smoking among black adolescents. Addict Behav (1992) 1.25
The effects of scheduling format and booster sessions on a broad-spectrum psychosocial approach to smoking prevention. J Behav Med (1983) 1.23
Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice. Blood (2001) 1.21
FRA10B structure reveals common elements in repeat expansion and chromosomal fragile site genesis. Mol Cell (1998) 1.20
Isolation and characterization of rabbit serum and milk transferrins. Evidence for difference in sialic acid content only. Biochemistry (1968) 1.20
Persistence of physiological self antigen is required for the regulation of self tolerance. J Immunol (2000) 1.19
An expanded mouse-human hybrid cell panel for mapping human chromosome 16. Ann Genet (1990) 1.19
Distribution of iron in reticulocytes after inhibition of heme synthesis with succinylacetone: examination of the intermediates involved in iron metabolism. Blood (1996) 1.18
Erythroid 5-aminolevulinate synthase is located on the X chromosome. Am J Hum Genet (1990) 1.17
Outcome of staged reconstructive surgery for hypoplastic left heart syndrome following antenatal diagnosis. Arch Dis Child (2001) 1.17
Chromosomal fragile site FRA16D and DNA instability in cancer. Cancer Res (2000) 1.17
Effects of interferon-gamma and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2. J Biol Chem (2000) 1.17
Interaction between phonological and semantic factors in auditory comprehension. Neuropsychologia (1981) 1.17
Smoking prevention among urban minority youth: assessing effects on outcome and mediating variables. Health Psychol (1992) 1.17
Cassini Imaging Science: initial results on Phoebe and Iapetus. Science (2005) 1.16
Frequent deletions at Xq28 indicate genetic heterogeneity in Hunter syndrome. Hum Genet (1991) 1.15
Cloning of the sulphamidase gene and identification of mutations in Sanfilippo A syndrome. Nat Genet (1995) 1.13
The uptake of iron and transferrin by the human malignant melanoma cell. Biochim Biophys Acta (1990) 1.11
New classes of common fragile sites induced by 5-azacytidine and bromodeoxyuridine. Hum Genet (1985) 1.11
5-Aminolevulinate synthase is at 3p21 and thus not the primary defect in X-linked sideroblastic anemia. Am J Hum Genet (1988) 1.11
The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes. Brain Res Mol Brain Res (1996) 1.07
Physical linkage of the fragile site FRA11B and a Jacobsen syndrome chromosome deletion breakpoint in 11q23.3. Hum Mol Genet (1994) 1.07
Quality of life as conveyed by pediatric patients with cancer. Qual Life Res (2004) 1.07
Genomic organization, exact localization, and tissue expression of the human CD26 (dipeptidyl peptidase IV) gene. Immunogenetics (1994) 1.06
Interleukin 4 is at 5q31 and interleukin 6 is at 7p15. Hum Genet (1988) 1.05
Chromosomal localization of the human alpha-L-iduronidase gene (IDUA) to 4p16.3. Am J Hum Genet (1990) 1.05
IL-12 p40 messenger RNA expression in target organs during acute graft-versus-host disease. Possible involvement of IFN-gamma. J Immunol (1996) 1.04
Normative expectations and the behavior of significant others: an integration of traditions in research on adolescents' cigarette smoking. Psychol Rep (1992) 1.04
The brn-2 gene regulates the melanocytic phenotype and tumorigenic potential of human melanoma cells. Oncogene (1995) 1.04
Impact of social influences and problem behavior on alcohol use among inner-city Hispanic and black adolescents. J Stud Alcohol (1999) 1.04
The kinetics of the interaction between rabbit transferrin and reticulocytes. Biochemistry (1969) 1.03
Development of potential iron chelators for the treatment of Friedreich's ataxia: ligands that mobilize mitochondrial iron. Biochim Biophys Acta (2001) 1.03
Gene structure and expression study of the SEDL gene for spondyloepiphyseal dysplasia tarda. Genomics (2000) 1.03
Regional mapping of the Batten disease locus (CLN3) to human chromosome 16p12. Am J Hum Genet (1991) 1.03
Acquisition of iron from transferrin regulates reticulocyte heme synthesis. J Biol Chem (1985) 1.02
A skills training approach to smoking prevention among Hispanic youth. J Behav Med (1989) 1.02
Control of transferrin receptor expression via nitric oxide-mediated modulation of iron-regulatory protein 2. J Biol Chem (1999) 1.02
The isochromosome 18p syndrome: confirmation of cytogenetic diagnosis in nine cases by in situ hybridization. Am J Hum Genet (1990) 1.01
Neuropsychological and neuroanatomical dimensions of ideomotor apraxia. Brain (1992) 1.01
Control of erythroid differentiation: possible role of the transferrin cycle. Cell (1986) 1.01
High-prevalence Borrelia miyamotoi infection among [corrected] wild turkeys (Meleagris gallopavo) in Tennessee. J Med Entomol (2010) 1.00
The antioxidant effects of a novel iron chelator salicylaldehyde isonicotinoyl hydrazone in the prevention of H(2)O(2) injury in adult cardiomyocytes. Cardiovasc Res (2000) 1.00
Iron chelators of the pyridoxal isonicotinoyl hydrazone class. III. Formation constants with calcium(II), magnesium(II) and zinc(II). Biol Met (1989) 1.00
The gene for the human IgA Fc receptor maps to 19q13.4. Hum Genet (1992) 1.00
A randomized controlled trial of the effects of multi-sensory stimulation (MSS) for people with dementia. Br J Clin Psychol (2001) 0.99
Mobilization of iron from reticulocytes. Identification of pyridoxal isonicotinoyl hydrazone as a new iron chelating agent. FEBS Lett (1979) 0.98
Association of Treacher Collins syndrome and translocation 6p21.31/16p13.11: exclusion of the locus from these candidate regions. Am J Hum Genet (1991) 0.98
Dimensions of assertiveness: differential relationships to substance use in early adolescence. J Consult Clin Psychol (1989) 0.98