PubRank

D R Cox

Author PubWeight™ 550.43‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Initial sequencing and analysis of the human genome. Nature 2001 212.86
2 Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. analysis and examples. Br J Cancer 1977 53.23
3 Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design. Br J Cancer 1976 22.55
4 Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21. Science 2001 15.54
5 A gene map of the human genome. Science 1996 14.32
6 Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes. Proc Natl Acad Sci U S A 1989 13.66
7 A physical map of 30,000 human genes. Science 1998 12.43
8 A physical map of the human genome. Nature 2001 12.39
9 Integration of cytogenetic landmarks into the draft sequence of the human genome. Nature 2001 10.96
10 An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science 2001 8.73
11 Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 1996 8.06
12 Report of the Committee on the Genetic Constitution of Chromosomes 13, 14, 15 and 16. Cytogenet Cell Genet 1985 6.87
13 Positive and negative effects of widespread badger culling on tuberculosis in cattle. Nature 2005 6.64
14 Structure and variability of human chromosome ends. Mol Cell Biol 1990 6.18
15 Impact of localized badger culling on tuberculosis incidence in British cattle. Nature 2003 4.84
16 TB policy and the badger culling trials. Vet Rec 2006 4.02
17 TB policy and the badger culling trials. Vet Rec 2006 3.67
18 An STS-based radiation hybrid map of the human genome. Genome Res 1997 3.57
19 High-throughput genotyping with single nucleotide polymorphisms. Genome Res 2001 3.55
20 Methods for estimating the case fatality ratio for a novel, emerging infectious disease. Am J Epidemiol 2005 3.40
21 Expression during embryogenesis of a mouse gene with sequence homology to the Drosophila engrailed gene. Cell 1985 3.30
22 Bovine tuberculosis: towards a future control strategy. Vet Rec 2000 3.27
23 Evolutionarily conserved sequences on human chromosome 21. Genome Res 2001 2.95
24 Mutations in the gene encoding cystatin B in progressive myoclonus epilepsy (EPM1) Science 1996 2.73
25 A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation. Nat Genet 1995 2.63
26 Quality of life measures in health care. III: Resource allocation. BMJ 1992 2.31
27 Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides. Nature 1983 2.25
28 Statistical methods for multipoint radiation hybrid mapping. Am J Hum Genet 1991 2.16
29 Genetic linkage analysis of bipolar affective disorder in an Old Order Amish pedigree. Hum Genet 1992 2.15
30 Exon trapping: a genetic screen to identify candidate transcribed sequences in cloned mammalian genomic DNA. Proc Natl Acad Sci U S A 1990 2.15
31 Statistical methods for polyploid radiation hybrid mapping. Genome Res 1995 2.15
32 Impacts of widespread badger culling on cattle tuberculosis: concluding analyses from a large-scale field trial. Int J Infect Dis 2007 2.03
33 On class differentials in educational attainment. Proc Natl Acad Sci U S A 2005 1.90
34 Functional effects of the mouse weaver mutation on G protein-gated inwardly rectifying K+ channels. Neuron 1996 1.85
35 Comparative chromosome mapping of a conserved homoeo box region in mouse and human. Nature 1985 1.77
36 Incubation period of AIDS in patients infected via blood transfusion. Nature 1987 1.71
37 The development of sequence-tagged sites for human chromosome 4. Hum Mol Genet 1993 1.55
38 A map of the distal region of the long arm of human chromosome 21 constructed by radiation hybrid mapping and pulsed-field gel electrophoresis. Genomics 1991 1.55
39 Some aspects of measurement error in explanatory variables for continuous and binary regression models. Stat Med 1998 1.53
40 Gene encoding the beta subunit of S100 protein is on chromosome 21: implications for Down syndrome. Science 1988 1.49
41 A cloned DNA segment from the telomeric region of human chromosome 4p is not detectably rearranged in Huntington disease patients. Proc Natl Acad Sci U S A 1990 1.47
42 Complex high-resolution linkage disequilibrium and haplotype patterns of single-nucleotide polymorphisms in 2.5 Mb of sequence on human chromosome 21. Genomics 2001 1.47
43 The end in sight for Huntington disease? Am J Hum Genet 1991 1.45
44 Exercise training in healthy type A middle-aged men: effects on behavioral and cardiovascular responses. Psychosom Med 1988 1.45
45 Statistical significance tests. Br J Clin Pharmacol 1982 1.41
46 Patterns of meiotic recombination on the long arm of human chromosome 21. Genome Res 2000 1.40
47 A yeast system for expression of human cystathionine beta-synthase: structural and functional conservation of the human and yeast genes. Proc Natl Acad Sci U S A 1994 1.33
48 Generalized least squares for the synthesis of correlated information. Biostatistics 2003 1.32
49 Report of the committee on the genetic constitution of chromosome 4. Cytogenet Cell Genet 1989 1.31
50 A high-resolution radiation hybrid map of the human genome draft sequence. Science 2001 1.30
51 Isolation and regional mapping of DNA sequences unique to human chromosome 21. Am J Hum Genet 1987 1.30
52 Bovine tuberculosis in cattle and badgers in localized culling areas. J Wildl Dis 2009 1.30
53 Pathogenesis and diagnosis of infections with Mycobacterium bovis in cattle. Independent Scientific Group on Cattle TB. Vet Rec 2000 1.27
54 Factors affecting indoor radon concentrations in the United Kingdom. Health Phys 1993 1.25
55 Experimental design and error detection for polyploid radiation hybrid mapping. Genome Res 1995 1.24
56 A yeast assay for functional detection of mutations in the human cystathionine beta-synthase gene. Hum Mol Genet 1995 1.24
57 Analysis of chromosome 22 deletions in neurofibromatosis type 2-related tumors. Am J Hum Genet 1992 1.23
58 Herd-level risk factors associated with tuberculosis breakdowns among cattle herds in England before the 2001 foot-and-mouth disease epidemic. Biol Lett 2005 1.23
59 Some aspects of analysis of covariance. Biometrics 1982 1.19
60 Progressive myoclonus epilepsy EPM1 locus maps to a 175-kb interval in distal 21q. Am J Hum Genet 1996 1.17
61 The metallothionein-I gene maps to mouse chromosome 8: implications for human Menkes' disease. Hum Genet 1983 1.15
62 Genes coding for sensitivity to interferon (IfRec) and soluble superoxide dismutase (SOD-1) are linked in mouse and man and map to mouse chromosome 16. Proc Natl Acad Sci U S A 1980 1.13
63 Dinucleotide repeat polymorphism located at D21S120. Nucleic Acids Res 1990 1.11
64 Discrimination between alternative binary response models. Biometrika 1967 1.11
65 Cloning of a candidate gene for ataxia-telangiectasia group D. Am J Hum Genet 1992 1.09
66 Mouse trisomy 16 as an animal model of human trisomy 21 (Down syndrome): production of viable trisomy 16 diploid mouse chimeras. Dev Biol 1984 1.07
67 Deletion of chromosome 21 and normal intelligence: molecular definition of the lesion. Hum Genet 1991 1.07
68 Selected locus and multiple panel models for radiation hybrid mapping. Am J Hum Genet 1996 1.06
69 Comparative gene mapping of human chromosome 21 and mouse chromosome 16. Ann N Y Acad Sci 1985 1.05
70 Social group size affects Mycobacterium bovis infection in European badgers (Meles meles). J Anim Ecol 2009 1.05
71 Radiation hybrid mapping. Proc Natl Acad Sci U S A 1991 1.05
72 Isolation and field-inversion gel electrophoresis analysis of DNA markers located close to the Huntington disease gene. Genomics 1989 1.04
73 Mouse trisomy 16: an animal model of human trisomy 21 (Down syndrome). Ann N Y Acad Sci 1985 1.02
74 Methylation at the Huntington disease-linked D4S95 locus. Am J Hum Genet 1989 1.01
75 Construction of a 750-kb bacterial clone contig and restriction map in the region of human chromosome 21 containing the progressive myoclonus epilepsy gene. Genome Res 1996 0.98
76 Identification of polymorphisms by genomic denaturing gradient gel electrophoresis: application to the proximal region of human chromosome 21. Nucleic Acids Res 1991 0.97
77 A radiation hybrid map of the proximal long arm of human chromosome 11 containing the multiple endocrine neoplasia type 1 (MEN-1) and bcl-1 disease loci. Am J Hum Genet 1991 0.96
78 Genetic variation in aldosterone synthase predicts plasma glucose levels. Proc Natl Acad Sci U S A 2001 0.95
79 Functional analysis of the neurofibromatosis type 2 protein by means of disease-causing point mutations. Am J Hum Genet 2000 0.94
80 De novo X;Y translocation associated with imperforate anus and retinal pigmentary abnormalities. Am J Med Genet 1987 0.94
81 Assignment of genes to the human X chromosome by the two-dimensional electrophoretic analysis of total cell proteins from rodent-human somatic cell hybrids. Am J Hum Genet 1981 0.94
82 The distribution of the incubation period for the acquired immunodeficiency syndrome (AIDS). Proc R Soc Lond B Biol Sci 1988 0.94
83 Herd-level risk factors of bovine tuberculosis in England and Wales after the 2001 foot-and-mouth disease epidemic. Int J Infect Dis 2011 0.93
84 Precise gene localization by phenotypic assay of radiation hybrid cells. Proc Natl Acad Sci U S A 2000 0.93
85 The chromosomal location of mouse interferon alpha genes. EMBO J 1984 0.93
86 Functional implications of gene dosage effects in trisomy 21. Hum Genet Suppl 1981 0.92
87 The glycine allele of a glycine/arginine polymorphism in the beta2-adrenergic receptor gene is associated with essential hypertension in a population of Chinese origin. Am J Hypertens 2001 0.92
88 Additive and multiplicative models for the joint effect of two risk factors. Biostatistics 2005 0.91
89 Sensitivity of HincII to CpG methylation. Nucleic Acids Res 1993 0.90
90 Trisomy 21: mechanisms and models. Ann N Y Acad Sci 1982 0.90
91 The prevalence, distribution and severity of detectable pathological lesions in badgers naturally infected with Mycobacterium bovis. Epidemiol Infect 2007 0.90
92 A radiation hybrid map of human chromosome 11q22-q23 containing the ataxia-telangiectasia disease locus. Genomics 1993 0.89
93 The delayed neurobehavioural sequelae of traumatic brain injury. Brain Inj 1991 0.89
94 Human GAP-43: its deduced amino acid sequence and chromosomal localization in mouse and human. Neuron 1988 0.89
95 The flock-to-flock force of infection for scrapie in Britain. Proc Biol Sci 2001 0.89
96 Assignment of the gene for beta 2-microglobulin (B2m) to mouse chromosome 2. Proc Natl Acad Sci U S A 1982 0.88
97 Genetic variation in the human urea transporter-2 is associated with variation in blood pressure. Hum Mol Genet 2001 0.87
98 Longitudinal study of nutrient and food intakes of white preschool children aged 24 to 60 months. J Am Diet Assoc 1999 0.87
99 A high resolution physical map of 2.5 Mbp of the Down syndrome region on chromosome 21. Hum Mol Genet 1994 0.87
100 Report of the committee on the genetic constitution of chromosome 21. Cytogenet Cell Genet 1990 0.87
101 The mouse homolog of the human amyloid beta protein (AD-AP) gene is located on the distal end of mouse chromosome 16: further extension of the homology between human chromosome 21 and mouse chromosome 16. Biochem Biophys Res Commun 1987 0.86
102 A simple example of a comparison involving quantal data. Biometrika 1966 0.86
103 A transcript map of the Down syndrome critical region on chromosome 21. Hum Mol Genet 1994 0.86
104 Stem cell deficiencies and thymic abnormalities in fetal mouse trisomy 16. J Exp Med 1985 0.85
105 On the relation between initial value and slope. Biostatistics 2005 0.85
106 A family of type I keratin genes and the homeobox-2 gene complex are closely linked to the rex locus on mouse chromosome 11. Genomics 1989 0.84
107 Recombination of 4p16 DNA markers in an unusual family with Huntington disease. Am J Hum Genet 1992 0.84
108 Tinea capitis due to Trichophyton soudanense. Arch Dermatol 1977 0.84
109 Lung transplantation for cystic fibrosis. Proc Am Thorac Soc 2009 0.83
110 Chromosomal assignment of the murine Gi alpha and Gs alpha genes. Implications for the obese mouse. J Biol Chem 1987 0.83
111 A radiation hybrid map of the distal short arm of human chromosome 11, containing the Beckwith-Wiedemann and associated embryonal tumor disease loci. Am J Hum Genet 1993 0.83
112 The murine Hox-2 cluster of homeo box containing genes maps distal on chromosome 11 near the tail-short (Ts) locus. Cytogenet Cell Genet 1986 0.82
113 Fine structure physical mapping of the region of mouse chromosome 10 homologous to human chromosome 21. Genomics 1991 0.82
114 Construction of cosmid contigs and high-resolution restriction mapping of the Huntington disease region of human chromosome 4. Hum Mol Genet 1993 0.81
115 Direction of association between bite wounds and Mycobacterium bovis infection in badgers: implications for transmission. PLoS One 2012 0.81
116 Production of viable adult trisomy 17 reversible diploid mouse chimeras. Proc Natl Acad Sci U S A 1982 0.80
117 A novel in vivo method to detect DNA sequence variation. Genome Res 1995 0.80
118 Recent evolution of DNA sequence homology in the pericentromeric regions of human acrocentric chromosomes. Cytogenet Cell Genet 1984 0.80
119 Time from infection with HIV to onset of AIDS in patients with haemophilia in the UK. Stat Med 1990 0.80
120 Gyrate atrophy of the choroid and retina: assignment of the ornithine aminotransferase structural gene to human chromosome 10 and mouse chromosome 7. Am J Hum Genet 1988 0.80
121 A map to the future. Nat Genet 1996 0.79
122 A novel and rapid method for isolating sequences adjacent to rare cutting sites and their use in physical mapping. Nucleic Acids Res 1991 0.78
123 Report of the Committee on the Genetic Constitution of Chromosomes 13, 14, 15, 16 and 17. Cytogenet Cell Genet 1984 0.78
124 Recent developments in the prenatal diagnosis of genetic diseases and birth defects. Annu Rev Genet 1983 0.78
125 Isolation of yeast artificial chromosome clones from 54 polymorphic loci mapped with high odds on human chromosome 4. Hum Mol Genet 1994 0.78
126 Assignment of the genes for sensitivity to interferon [IfRec] and soluble superoxide dismutase [SOD-1] to mouse chromosome. Ann N Y Acad Sci 1980 0.78
127 A radiation hybrid map of the region on human chromosome 22 containing the neurofibromatosis type 2 locus. Genomics 1992 0.78
128 Dinucleotide repeat polymorphism located at D4S169. Nucleic Acids Res 1991 0.77
129 Large tables. Biostatistics 2001 0.75
130 Mouse trisomy 16 as an animal model of human trisomy 21: a new approach for studying the pathogenesis of Down syndrome. Mead Johnson Symp Perinat Dev Med 1983 0.75
131 Statistical basis of public policy. Qualitative and quantitative aspects should not be confused. BMJ 1997 0.75
132 Specific detection of antigen-binding cells by localized growth of bacteria. Proc Natl Acad Sci U S A 1971 0.75
133 TaqI RFLP at D21S137. Nucleic Acids Res 1991 0.75
134 Multivariate meta-analysis: a comment. Stat Med 2011 0.75
135 Re: TB policy and the ISG's findings. Vet Rec 2007 0.75
136 Comments on paper by C. E. Frangakis, D. B. Rubin and X.-H. Zhao. Biostatistics 2002 0.75
137 Cloning of the Huntington disease region in yeast artificial chromosomes. Hum Mol Genet 1992 0.75
138 Proceedings of the Symposium on Designs for Clinical Cancer Research. Summary views: A statistician's perspective. Cancer Treat Rep 1980 0.75
139 On the consistency of the MMPI in borderline personality disorder. Percept Mot Skills 1986 0.75
140 Potential use of vaccination in cattle or badgers to control bovine tuberculosis. Dev Biol (Basel) 2004 0.75
141 Evidence for enzyme subunit complementation in somatic cell heterokaryons. Exp Cell Res 1976 0.75
142 Asplenia syndrome after fetal exposure to warfarin. Lancet 1977 0.75
143 Fieller's theorem and a generalization. Biometrika 1967 0.75
144 Epidemiological and statistical aspects of the AIDS epidemic: introduction. Philos Trans R Soc Lond B Biol Sci 1989 0.75
145 Scrapie in Britain during the BSE years. Nature 2000 0.75
146 Mathematical biology and medical statistics: contributions to the understanding of AIDS epidemiology. Stat Methods Med Res 2001 0.75