Published in Vaccine on January 01, 1993
The woodchuck as an animal model for pathogenesis and therapy of chronic hepatitis B virus infection. World J Gastroenterol (2007) 1.77
Hybrid hepatitis B virus core-pre-S proteins synthesized in avirulent Salmonella typhimurium and Salmonella typhi for oral vaccination. Infect Immun (1994) 1.31
Characterization of T-cell response to woodchuck hepatitis virus core protein and protection of woodchucks from infection by immunization with peptides containing a T-cell epitope. J Virol (1997) 1.27
Safety and enhanced immunogenicity of a hepatitis B core particle Plasmodium falciparum malaria vaccine formulated in adjuvant Montanide ISA 720 in a phase I trial. Infect Immun (2005) 1.17
Immunization of woodchucks with plasmids expressing woodchuck hepatitis virus (WHV) core antigen and surface antigen suppresses WHV infection. J Virol (1999) 1.11
T-Cell response to woodchuck hepatitis virus (WHV) antigens during acute self-limited WHV infection and convalescence and after viral challenge. J Virol (1998) 1.10
DNA immunization with fusion of CTLA-4 to hepatitis B virus (HBV) core protein enhanced Th2 type responses and cleared HBV with an accelerated kinetic. PLoS One (2011) 1.01
Bicistronic woodchuck hepatitis virus core and gamma interferon DNA vaccine can protect from hepatitis but does not elicit sterilizing antiviral immunity. J Virol (2006) 0.96
Acute resolving woodchuck hepatitis virus (WHV) infection is associated with a strong cytotoxic T-lymphocyte response to a single WHV core peptide. J Virol (2007) 0.95
Protection against woodchuck hepatitis virus (WHV) infection by gene gun coimmunization with WHV core and interleukin-12. J Virol (2001) 0.90
Comparative antigenicity and immunogenicity of hepadnavirus core proteins. J Virol (2005) 0.85
A new sensitive method for qualitative and quantitative assay of neomycin phosphotransferase in crude cell extracts. Gene (1984) 7.36
Signals regulating hepatitis B surface antigen transcription. Nature (1983) 5.02
Comparative sequence analysis of duck and human hepatitis B virus genomes. J Med Virol (1985) 4.68
Replication strategy of human hepatitis B virus. J Virol (1987) 4.42
Transcripts and the putative RNA pregenome of duck hepatitis B virus: implications for reverse transcription. Cell (1985) 4.41
Vesicular stomatitis virus infects and matures only through the basolateral surface of the polarized epithelial cell line, MDCK. Cell (1984) 4.24
Designing medical informatics research and library--resource projects to increase what is learned. J Am Med Inform Assoc (1995) 3.74
"U" curve association of blood pressure and mortality in hemodialysis patients. Medical Directors of Dialysis Clinic, Inc. Kidney Int (1998) 3.53
Hepatitis B virus transcription in the infected liver. EMBO J (1984) 3.44
A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients. J Virol (1995) 3.35
Retracted Identification by anti-idiotype antibodies of an intracellular membrane protein that recognizes a mammalian endoplasmic reticulum retention signal. Nature (1990) 3.33
Isolation and characterization of a hepatitis B virus endemic in herons. J Virol (1988) 3.23
Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase a (MMP-2) are able to generate active enzyme. J Biol Chem (1996) 3.00
Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1. J Cell Biol (1997) 2.98
A conformational switch controlling HIV-1 morphogenesis. EMBO J (2000) 2.86
Cloned HBV DNA causes hepatitis in chimpanzees. Nature (1982) 2.80
Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis. J Immunol (1990) 2.73
Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus. Hepatology (2001) 2.71
The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study. J Biol Chem (1998) 2.71
Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch. EMBO Rep (2001) 2.70
Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinases. Eur J Biochem (1997) 2.63
A novel technique for laminoplasty augmentation of spinal canal area using titanium miniplate stabilization. A computerized morphometric analysis. Spine (Phila Pa 1976) (1996) 2.59
Meeting clinician information needs by integrating access to the medical record and knowledge resources via the Web. Proc AMIA Annu Fall Symp (1997) 2.41
Regulation of p53 activity in nuclear bodies by a specific PML isoform. EMBO J (2000) 2.38
Stoichiometry and assembly of a recombinant GABAA receptor subtype. J Neurosci (1997) 2.35
Limited humoral immunity in hepatitis C virus infection. Gastroenterology (1999) 2.31
GABA(A) receptor subunits in the rat hippocampus I: immunocytochemical distribution of 13 subunits. Neuroscience (1997) 2.27
Antibodies in human sera specific to hypervariable region 1 of hepatitis C virus can block viral attachment. Virology (1995) 2.25
IFN enhance expression of Sp100, an autoantigen in primary biliary cirrhosis. J Immunol (1992) 2.24
The nuclear dot protein sp100, characterization of domains necessary for dimerization, subcellular localization, and modification by small ubiquitin-like modifiers. J Biol Chem (1999) 2.21
Infectious hepatitis B virus from cloned DNA of known nucleotide sequence. Proc Natl Acad Sci U S A (1985) 2.20
Isolation of Aeromonas hydrophila from a metropolitan water supply: seasonal correlation with clinical isolates. Appl Environ Microbiol (1984) 2.14
Wild-type and e antigen-minus hepatitis B viruses and course of chronic hepatitis. Proc Natl Acad Sci U S A (1991) 2.05
Transmission of hepatitis C virus to children and husbands by women infected with contaminated anti-D immunoglobulin. Lancet (1995) 2.03
Nucleotide sequence of the tms genes of the pTiA6NC octopine Ti plasmid: two gene products involved in plant tumorigenesis. Proc Natl Acad Sci U S A (1984) 2.01
Putative reverse transcriptase intermediates of human hepatitis B virus in primary liver carcinomas. Science (1986) 2.00
Acute bilineal leukemia: a rare disease with poor outcome. Leukemia (2007) 1.98
Monoclonal antibodies against chromosomal proteins of Drosophila melanogaster: establishment of antibody producing cell lines and partial characterization of corresponding antigens. Chromosoma (1980) 1.97
Expression of the hepatitis B virus core gene in vitro and in vivo. J Virol (1987) 1.96
The position of heterologous epitopes inserted in hepatitis B virus core particles determines their immunogenicity. J Virol (1992) 1.95
A recombinant Salmonella typhimurium vaccine induces local immunity by four different routes of immunization. Infect Immun (1995) 1.91
Presence of Staphylococcus aureus with reduced susceptibility to vancomycin in Germany. Eur J Clin Microbiol Infect Dis (1999) 1.87
A redox-based O2 sensor in rat pulmonary vasculature. Circ Res (1993) 1.83
Nationwide cerebrovascular disease morbidity study. Stroke (1972) 1.82
Cloned duck hepatitis B virus DNA is infectious in Pekin ducks. J Virol (1984) 1.80
Expression of hepatitis B antigens with a simian virus 40 vector. J Virol (1984) 1.80
Structure of human ferritin light subunit messenger RNA: comparison with heavy subunit message and functional implications. Proc Natl Acad Sci U S A (1985) 1.79
A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis. Hepatology (2001) 1.78
Infectious hepatitis B virus variant defective in pre-S2 protein expression in a chronic carrier. Virology (1993) 1.75
Generation of stable mRNA fragments and translation of N-truncated proteins induced by antisense oligodeoxynucleotides. Mol Cell (2001) 1.74
High prevalence of human metapneumovirus infection in young children and genetic heterogeneity of the viral isolates. J Clin Microbiol (2003) 1.73
Naturally occurring variants of hepatitis B virus. Adv Virus Res (1999) 1.72
Activation of a heterogeneous hepatitis B (HB) core and e antigen-specific CD4+ T-cell population during seroconversion to anti-HBe and anti-HBs in hepatitis B virus infection. J Virol (1995) 1.71
Comparison of solid phase test systems for demonstrating antibodies against hepatitis A virus (anti-Hav) of the IgM-class. J Med Virol (1980) 1.68
Transmission of hepatitis C virus from a patient to an anesthesiology assistant to five patients. N Engl J Med (2000) 1.67
Molecular biology of viral and nonviral retroelements. Trends Genet (1989) 1.65
Serological pattern "anti-HBc alone": report on a workshop. J Med Virol (2000) 1.65
Influence of feeding and sham feeding upon serum gastrin and gastric acid secretion in control subjects and duodenal ulcer patients. Scand J Gastroenterol (1974) 1.63
Identification of a novel selD homolog from eukaryotes, bacteria, and archaea: is there an autoregulatory mechanism in selenocysteine metabolism? Proc Natl Acad Sci U S A (1996) 1.63
Body language: the function of PML nuclear bodies in apoptosis regulation. Cell Death Differ (2003) 1.62
Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis. Proc Natl Acad Sci U S A (1997) 1.60
Informatics and medical libraries: changing needs and changing roles. Acad Med (1995) 1.60
Amino acid biosynthesis in the spirochete Leptospira: evidence for a novel pathway of isoleucine biosynthesis. J Bacteriol (1974) 1.60
Comparative in vitro activities of several new fluoroquinolones and beta-lactam antimicrobial agents against community isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother (1990) 1.59
Detection of an element of the SV40 late promoter in vectors used for expression studies in COS cells. EMBO J (1983) 1.57
Muscle testing response to provocative vertebral challenge and spinal manipulation: a randomized controlled trial of construct validity. J Manipulative Physiol Ther (1994) 1.57
Combination but not single-agent methotrexate chemotherapy for gestational trophoblastic tumors increases the incidence of second tumors. J Clin Oncol (1996) 1.54
The organization of the digital library. Acad Med (1995) 1.54
Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in health care workers (HCWs): guidelines for prevention of transmission of HBV and HCV from HCW to patients. J Clin Virol (2003) 1.53
A posterolateral microsurgical approach to extreme-lateral lumbar disc herniation. J Neurosurg (1995) 1.52
Interferon-modulated expression of genes encoding the nuclear-dot-associated proteins Sp100 and promyelocytic leukemia protein (PML). Eur J Biochem (1996) 1.50
Phenotypic and functional deficiency of natural killer cells in patients with chronic fatigue syndrome. J Immunol (1987) 1.50
The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein. J Biol Chem (2000) 1.49
Structural analysis of membrane-bound retrovirus capsid proteins. EMBO J (1997) 1.48
Immunoglobulin M antibodies to hepatitis B core antigen: evaluation of enzyme immunoassay for diagnosis of hepatitis B virus infection. J Clin Microbiol (1981) 1.48
Twenty-four-hour gastric luminal pH in normal subjects: influence of probe position, food, posture, and duodenogastric reflux. Am J Gastroenterol (1994) 1.48
Antibodies to hepatitis C virus. Lancet (1989) 1.47
Monoclonal nicotine-specific antibodies reduce nicotine distribution to brain in rats: dose- and affinity-response relationships. Drug Metab Dispos (2005) 1.47
Variation in the frequency and type of sperm chromosomal abnormalities among normal men. Hum Genet (1987) 1.46
Clinical, epidemiologic, and virologic studies in four clusters of the chronic fatigue syndrome. Arch Intern Med (1992) 1.46
Nuclear dots: actors on many stages. Immunobiology (1997) 1.45
Reactivity of leg alignment to articular pressure testing: evaluation of a diagnostic test using a randomized crossover clinical trial approach. J Manipulative Physiol Ther (1993) 1.44
Risk of hepatitis C transmission from infected medical staff to patients: model-based calculations for surgical settings. Arch Intern Med (2000) 1.44
Heterogeneity and common features of defective hepatitis B virus genomes derived from spliced pregenomic RNA. Virology (1997) 1.42
OB-BP1/Siglec-6. a leptin- and sialic acid-binding protein of the immunoglobulin superfamily. J Biol Chem (1999) 1.41
A roentgenological evaluation of the relationship between segmental motion and malalignment in lateral bending. J Manipulative Physiol Ther (1992) 1.40
Responsiveness of leg alignment changes associated with articular pressure testing to spinal manipulation: the use of a randomized clinical trial design to evaluate a diagnostic test with a dichotomous outcome. J Manipulative Physiol Ther (1993) 1.40
Structure and subunit composition of GABA(A) receptors. Neurochem Int (1999) 1.39
A new avian hepadnavirus infecting snow geese (Anser caerulescens) produces a significant fraction of virions containing single-stranded DNA. Virology (1999) 1.38
Neurosurgery as a first foundation year training post. Br J Neurosurg (2010) 1.38
Prevalence of antibodies to hepatitis C virus in patients on peritoneal dialysis--a multicenter study. Clin Nephrol (1993) 1.37
Soluble and membrane-bound forms of signaling lymphocytic activation molecule (SLAM) induce proliferation and Ig synthesis by activated human B lymphocytes. J Exp Med (1997) 1.37
The amyloid precursor protein of Alzheimer's disease is released by human platelets. J Biol Chem (1990) 1.36
Structure of hepatitis B virus core and e-antigen. A single precore amino acid prevents nucleocapsid assembly. J Biol Chem (1993) 1.36
A wheat HMW glutenin subunit gene reveals a highly repeated structure. Nucleic Acids Res (1985) 1.36
Two nuclear dot-associated proteins, PML and Sp100, are often co-autoimmunogenic in patients with primary biliary cirrhosis. Scand J Immunol (1995) 1.36
Amplification of full-length hepatitis B virus genomes from samples from patients with low levels of viremia: frequency and functional consequences of PCR-introduced mutations. J Clin Microbiol (1998) 1.34