Published in Scand J Immunol on August 01, 1995
PML contributes to a cellular mechanism of repression of herpes simplex virus type 1 infection that is inactivated by ICP0. J Virol (2006) 3.03
Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1. J Cell Biol (1997) 2.98
Alphaherpesvirus proteins related to herpes simplex virus type 1 ICP0 affect cellular structures and proteins. J Virol (2000) 2.25
Covalent modification of the transactivator protein IE2-p86 of human cytomegalovirus by conjugation to the ubiquitin-homologous proteins SUMO-1 and hSMT3b. J Virol (2000) 1.91
ICP0 induces the accumulation of colocalizing conjugated ubiquitin. J Virol (2000) 1.90
Herpes simplex virus type 1 genomes are associated with ND10 nuclear substructures in quiescently infected human fibroblasts. J Virol (2007) 1.65
Recruitment of herpes simplex virus type 1 transcriptional regulatory protein ICP4 into foci juxtaposed to ND10 in live, infected cells. J Virol (2003) 1.50
Analysis of the functions of herpes simplex virus type 1 regulatory protein ICP0 that are critical for lytic infection and derepression of quiescent viral genomes. J Virol (2009) 1.48
PML isoforms I and II participate in PML-dependent restriction of HSV-1 replication. J Cell Sci (2010) 1.35
Comparison of the biological and biochemical activities of several members of the alphaherpesvirus ICP0 family of proteins. J Virol (2010) 1.32
Inhibition of different Lassa virus strains by alpha and gamma interferons and comparison with a less pathogenic arenavirus. J Virol (2004) 1.30
Mediation of Epstein-Barr virus EBNA-LP transcriptional coactivation by Sp100. EMBO J (2005) 1.28
PIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemia. Mol Cell Biol (1999) 1.25
Herpes simplex virus 1 ubiquitin ligase ICP0 interacts with PML isoform I and induces its SUMO-independent degradation. J Virol (2012) 1.16
Human cytomegalovirus infection causes degradation of Sp100 proteins that suppress viral gene expression. J Virol (2011) 1.09
Regulation of double-strand break-induced mammalian homologous recombination by UBL1, a RAD51-interacting protein. Nucleic Acids Res (2000) 1.06
Cellular localization, expression, and structure of the nuclear dot protein 52. J Cell Biol (1997) 1.02
Autoantibodies as prognostic markers in autoimmune liver disease. Dig Dis Sci (2010) 1.01
Human neuron-committed teratocarcinoma NT2 cell line has abnormal ND10 structures and is poorly infected by herpes simplex virus type 1. J Virol (2001) 0.96
Report of the First International Consensus on Standardized Nomenclature of Antinuclear Antibody HEp-2 Cell Patterns 2014-2015. Front Immunol (2015) 0.96
A highly amplified mouse gene is homologous to the human interferon-responsive Sp100 gene encoding an autoantigen associated with nuclear dots. Mol Cell Biol (1996) 0.90
Autoantibodies to GW bodies and other autoantigens in primary biliary cirrhosis. Clin Exp Immunol (2010) 0.90
Sp100 isoform-specific regulation of human adenovirus 5 gene expression. J Virol (2014) 0.89
Primary biliary cirrhosis: what do autoantibodies tell us? World J Gastroenterol (2010) 0.89
Autoantigens in primary biliary cirrhosis. J Clin Pathol (2000) 0.86
Optimized detection of circulating anti-nuclear envelope autoantibodies by immunofluorescence. BMC Immunol (2006) 0.83
Anti-multiple nuclear dots (anti-MND) and anti-SP100 antibodies in hepatic and rheumatological disorders. Clin Exp Immunol (2002) 0.79
Autoantibodies in liver disease: important clues for the diagnosis, disease activity and prognosis. Auto Immun Highlights (2013) 0.78
Primary biliary cirrhosis: From bench to bedside. World J Gastrointest Pharmacol Ther (2015) 0.78
Meta-analysis assessment of GP210 and SP100 for the diagnosis of primary biliary cirrhosis. PLoS One (2014) 0.77
Presence of disease specific autoantibodies against liver sinusoidal cells in primary biliary cirrhosis. World J Hepatol (2013) 0.77
SP140L, an Evolutionarily Recent Member of the SP100 Family, Is an Autoantigen in Primary Biliary Cirrhosis. J Immunol Res (2015) 0.77
Diagnostic autoantibodies for autoimmune liver diseases. Clin Transl Immunology (2017) 0.75
A new sensitive method for qualitative and quantitative assay of neomycin phosphotransferase in crude cell extracts. Gene (1984) 7.36
Signals regulating hepatitis B surface antigen transcription. Nature (1983) 5.02
Comparative sequence analysis of duck and human hepatitis B virus genomes. J Med Virol (1985) 4.68
Replication strategy of human hepatitis B virus. J Virol (1987) 4.42
Transcripts and the putative RNA pregenome of duck hepatitis B virus: implications for reverse transcription. Cell (1985) 4.41
Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0). J Gen Virol (1993) 4.32
The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion. EMBO J (1994) 4.29
Hepatitis B virus transcription in the infected liver. EMBO J (1984) 3.44
A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients. J Virol (1995) 3.35
Isolation and characterization of a hepatitis B virus endemic in herons. J Virol (1988) 3.23
Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase a (MMP-2) are able to generate active enzyme. J Biol Chem (1996) 3.00
Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1. J Cell Biol (1997) 2.98
Cloned HBV DNA causes hepatitis in chimpanzees. Nature (1982) 2.80
Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis. J Immunol (1990) 2.73
Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus. Hepatology (2001) 2.71
The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study. J Biol Chem (1998) 2.71
Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinases. Eur J Biochem (1997) 2.63
Regulation of p53 activity in nuclear bodies by a specific PML isoform. EMBO J (2000) 2.38
IFN enhance expression of Sp100, an autoantigen in primary biliary cirrhosis. J Immunol (1992) 2.24
The nuclear dot protein sp100, characterization of domains necessary for dimerization, subcellular localization, and modification by small ubiquitin-like modifiers. J Biol Chem (1999) 2.21
Infectious hepatitis B virus from cloned DNA of known nucleotide sequence. Proc Natl Acad Sci U S A (1985) 2.20
Wild-type and e antigen-minus hepatitis B viruses and course of chronic hepatitis. Proc Natl Acad Sci U S A (1991) 2.05
Putative reverse transcriptase intermediates of human hepatitis B virus in primary liver carcinomas. Science (1986) 2.00
Monoclonal antibodies against chromosomal proteins of Drosophila melanogaster: establishment of antibody producing cell lines and partial characterization of corresponding antigens. Chromosoma (1980) 1.97
Expression of the hepatitis B virus core gene in vitro and in vivo. J Virol (1987) 1.96
The position of heterologous epitopes inserted in hepatitis B virus core particles determines their immunogenicity. J Virol (1992) 1.95
Cloned duck hepatitis B virus DNA is infectious in Pekin ducks. J Virol (1984) 1.80
Expression of hepatitis B antigens with a simian virus 40 vector. J Virol (1984) 1.80
Structure of human ferritin light subunit messenger RNA: comparison with heavy subunit message and functional implications. Proc Natl Acad Sci U S A (1985) 1.79
A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis. Hepatology (2001) 1.78
Human anti-centromere sera recognise a 19.5 kD non-histone chromosomal protein from HeLa cells. Clin Exp Immunol (1984) 1.78
Infectious hepatitis B virus variant defective in pre-S2 protein expression in a chronic carrier. Virology (1993) 1.75
Generation of stable mRNA fragments and translation of N-truncated proteins induced by antisense oligodeoxynucleotides. Mol Cell (2001) 1.74
Naturally occurring variants of hepatitis B virus. Adv Virus Res (1999) 1.72
Activation of a heterogeneous hepatitis B (HB) core and e antigen-specific CD4+ T-cell population during seroconversion to anti-HBe and anti-HBs in hepatitis B virus infection. J Virol (1995) 1.71
Molecular biology of viral and nonviral retroelements. Trends Genet (1989) 1.65
Serological pattern "anti-HBc alone": report on a workshop. J Med Virol (2000) 1.65
Body language: the function of PML nuclear bodies in apoptosis regulation. Cell Death Differ (2003) 1.62
Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis. Proc Natl Acad Sci U S A (1997) 1.60
Detection of an element of the SV40 late promoter in vectors used for expression studies in COS cells. EMBO J (1983) 1.57
Interferon-modulated expression of genes encoding the nuclear-dot-associated proteins Sp100 and promyelocytic leukemia protein (PML). Eur J Biochem (1996) 1.50
The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein. J Biol Chem (2000) 1.49
Identification of human Sm and (U1) RNP antigens by immunoblotting. J Immunol Methods (1983) 1.45
Nuclear dots: actors on many stages. Immunobiology (1997) 1.45
Heterogeneity and common features of defective hepatitis B virus genomes derived from spliced pregenomic RNA. Virology (1997) 1.42
A new avian hepadnavirus infecting snow geese (Anser caerulescens) produces a significant fraction of virions containing single-stranded DNA. Virology (1999) 1.38
Amplification of full-length hepatitis B virus genomes from samples from patients with low levels of viremia: frequency and functional consequences of PCR-introduced mutations. J Clin Microbiol (1998) 1.34
Epitope mapping with a recombinant human 68-kDa (U1) ribonucleoprotein antigen reveals heterogeneous autoantibody profiles in human autoimmune sera. J Immunol (1988) 1.34
Monoclonal antibody directed against RNA polymerase II of Drosophila melanogaster. Mol Gen Genet (1980) 1.33
Internal entry of ribosomes and ribosomal scanning involved in hepatitis B virus P gene expression. J Virol (1989) 1.31
Precore mutant hepatitis B virus infection and liver disease. Gastroenterology (1992) 1.31
Scl 70 autoantibodies from scleroderma patients recognize a 95 kDa protein identified as DNA topoisomerase I. Chromosoma (1986) 1.30
Hepatitis B virus nucleocapsid/pre-S2 fusion proteins expressed in attenuated Salmonella for oral vaccination. J Immunol (1990) 1.27
PIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemia. Mol Cell Biol (1999) 1.25
Identification and analysis of a new hepadnavirus in white storks. Virology (2001) 1.24
A new hepatitis B virus strain in patients with severe anti-HBe positive chronic hepatitis B. J Hepatol (1990) 1.24
A recombinant Chinese hamster ovary cell line containing a 300-fold amplified tetramer of the hepatitis B genome together with a double selection marker expresses high levels of viral protein. J Mol Biol (1986) 1.23
Enhancement of hepatitis B virus infection by noninfectious subviral particles. J Virol (1998) 1.22
Isolation and characterization of the human hepatic lipase gene. J Biol Chem (1990) 1.22
Type, prevalence, and significance of core promoter/enhancer II mutations in hepatitis B viruses from immunosuppressed patients with severe liver disease. J Virol (1996) 1.21
A new hepatitis B virus variant in a chronic carrier with multiple episodes of viral reactivation and acute hepatitis. Virology (1990) 1.21
Expression mechanism of the hepatitis B virus (HBV) C gene and biosynthesis of HBe antigen. Virology (1989) 1.21
Full-length and truncated versions of the hepatitis B virus (HBV) X protein (pX) transactivate the cmyc protooncogene at the transcriptional level. Biochem Biophys Res Commun (1991) 1.20
Transcriptional regulation of apolipoprotein A-I gene expression by the nuclear receptor RORalpha. J Biol Chem (1997) 1.18
The interferon (IFN)-stimulated gene Sp100 promoter contains an IFN-gamma activation site and an imperfect IFN-stimulated response element which mediate type I IFN inducibility. J Biol Chem (1996) 1.17
Membrane-type-2 matrix metalloproteinase can initiate the processing of progelatinase A and is regulated by the tissue inhibitors of metalloproteinases. Eur J Biochem (1997) 1.16
Hepatitis B virus genomes that cannot synthesize pre-S2 proteins occur frequently and as dominant virus populations in chronic carriers in Italy. Virology (1992) 1.15
Frequent and rapid emergence of mutated pre-C sequences in HBV from e-antigen positive carriers who seroconvert to anti-HBe during interferon treatment. Virology (1992) 1.15
Absence of mutations in the YMDD motif/B region of the hepatitis B virus polymerase in famciclovir therapy failure. J Hepatol (1999) 1.14
Alterations in thyroid status modulate apolipoprotein, hepatic triglyceride lipase, and low density lipoprotein receptor in rats. Endocrinology (1990) 1.14
Effect of interferon alpha on hepatitis B virus replication and gene expression in transiently transfected human hepatoma cells. J Hepatol (1999) 1.13
Potent inhibition of hepatitis B virus production in vitro by modified pyrimidine nucleosides. Antimicrob Agents Chemother (1990) 1.12
A recombinant autoantigen derived from the human (U1) small nuclear RNP-specific 68-kd protein. Expression in Escherichia coli and serodiagnostic application. Arthritis Rheum (1988) 1.12
Wild-type levels of pregenomic RNA and replication but reduced pre-C RNA and e-antigen synthesis of hepatitis B virus with C(1653) --> T, A(1762) --> T and G(1764) --> A mutations in the core promoter. J Gen Virol (1998) 1.11
Naturally occurring hepatitis B virus genomes bearing the hallmarks of retroviral G-->A hypermutation. Virology (1997) 1.11
Prevalence and type of pre-C HBV mutants in anti-HBe positive carriers with chronic liver disease in a highly endemic area. Virology (1991) 1.10
Increased hepatocyte turnover and inhibition of woodchuck hepatitis B virus replication by adefovir in vitro do not lead to reduction of the closed circular DNA. Hepatology (2000) 1.09
Detailed characterization of the binding site of the lipoprotein lipase-specific monoclonal antibody 5D2. J Lipid Res (1998) 1.09
Duck hepatitis B virus expresses a regulatory HBx-like protein from a hidden open reading frame. J Virol (2001) 1.08
Splice variants of the nuclear dot-associated Sp100 protein contain homologies to HMG-1 and a human nuclear phosphoprotein-box motif. J Cell Sci (1999) 1.05
Hepatitis B virus genomes of patients with fulminant hepatitis do not share a specific mutation. Hepatology (1996) 1.05
Human hepatic triglyceride lipase: cDNA cloning, amino acid sequence and expression in a cultured cell line. Differentiation (1987) 1.03
Prevalence, kinetics, and therapeutic modulation of autoantibodies against Sp100 and promyelocytic leukemia protein in a large cohort of patients with primary biliary cirrhosis. Hepatology (1997) 1.03
Interrupted replication of hepatitis B virus in liver tissue of HBsAg carriers with hepatocellular carcinoma. Virology (1988) 1.02
Cellular localization, expression, and structure of the nuclear dot protein 52. J Cell Biol (1997) 1.02
The RNA-binding protein La contributes to cell proliferation and CCND1 expression. Oncogene (2010) 1.02
Autoantibodies against "nuclear dots" in primary biliary cirrhosis. Semin Liver Dis (1997) 1.01
Latency and reactivation of a precore mutant hepatitis B virus in a chronically infected patient. J Hepatol (1990) 1.01